The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Chemical Synthesis of Proteins
Open accessAbstract
▪ Abstract Proteins have become accessible targets for chemical synthesis. The basic strategy is to use native chemical ligation, Staudinger ligation, or other orthogonal chemical reactions to couple synthetic peptides. The ligation reactions are compatible with a variety of solvents and proceed in solution or on a solid support. Chemical synthesis enables a level of control on protein composition that greatly exceeds that attainable with ribosome-mediated biosynthesis. Accordingly, the chemical synthesis of proteins is providing previously unattainable insight into the structure and function of proteins.
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Cites
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Cited by
Chemical synthesis of proteins using peptide hydrazides as thioester surrogates
Zheng, J.-S., Tang, S., Qi, Y.-K., Wang, Z.-P., & Liu, L. (2013) · Nature Protocols · doi:10.1038/nprot.2013.152 · Cited by 537
Selective Covalent Protein Immobilization: Strategies and Applications
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Protein chemical synthesis by serine and threonine ligation
Zhang, Y., Xu, C., Lam, H. Y., Lee, C. L., & Li, X. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1221012110 · Cited by 272
Dual Native Chemical Ligation at Lysine
Yang, R., Pasunooti, K. K., Li, F., Liu, X.-W., & Liu, C.-F. (2009) · Journal of the American Chemical Society · doi:10.1021/ja905491p · Cited by 260
Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis
Shi, X., DeCiucis, M., Grabinska, K. A., Kanyo, J., Liu, A., Lam, T. T., & Shen, H. (2024) · Molecular Cell · doi:10.1016/j.molcel.2023.12.008 · Cited by 54
Metadata
- Authors
- Nilsson, B. L., Soellner, M. B., & Raines, R. T.
- Venue
- Annual Review of Biophysics and Biomolecular Structure
- Publisher
- Annual Reviews
- Published
- 2005-06-01
- Volume
- 34
- Issue
- 1
- Pages
- 91-118
- ISSN
- 1056-8700 (ISSN-L)
- 1545-4266
- OpenAlex
- W2103008129
- Cited by
- 329
- References
- 98
- FWCI
- 8.76
- Type
- journal article
- Language
- en
- Open access
- green
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