The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.
Assembling Neural Crest Regulatory Circuits into a Gene Regulatory Network
Open accessAbstract
The neural crest is a multipotent stem cell–like population that gives rise to a wide range of derivatives in the vertebrate embryo including elements of the craniofacial skeleton and peripheral nervous system as well as melanocytes. The neural crest forms in a series of regulatory steps that include induction and specification of the prospective neural crest territory–neural plate border, specification of bona fide neural crest progenitors, and differentiation into diverse derivatives. These individual processes during neural crest ontogeny are controlled by regulatory circuits that can be assembled into a hierarchical gene regulatory network (GRN). Here we present an overview of the GRN that orchestrates the formation of cranial neural crest cells. Formulation of this network relies on information largely inferred from gene perturbation studies performed in several vertebrate model organisms. Our representation of the cranial neural crest GRN also includes information about direct regulatory interactions obtained from the cis-regulatory analyses performed to date, which increases the resolution of the architectural circuitry within the network.
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Cites
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Simões-Costa, M., & Bronner, M. E. (2015) · Development · doi:10.1242/dev.105445 · Cited by 649
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Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest
Rada-Iglesias, A., Bajpai, R., Prescott, S., Brugmann, S. A., Swigut, T., & Wysocka, J. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.07.006 · Cited by 314
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor
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Metadata
- Authors
- Betancur, P., Bronner-Fraser, M., & Sauka-Spengler, T.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2010-11-10
- Volume
- 26
- Issue
- 1
- Pages
- 581-603
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2144172863
- Cited by
- 305
- References
- 104
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- green
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