The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Vacuolar Import of Proteins and Organelles From The Cytoplasm
Abstract
▪ Abstract Many cellular processes require a balance between protein synthesis and protein degradation. The vacuole/lysosome is the main site of protein and organellar turnover within the cell due to its ability to sequester numerous hydrolases within a membrane-enclosed compartment. Several mechanisms are used to deliver substrates, as well as resident hydrolases, to this organelle. The delivery processes involve dynamic rearrangements of membrane. In addition, continual adjustments are made to respond to changes in environmental conditions. In this review, we focus on recent progress made in analyzing these delivery processes at a molecular level. The identification of protein components involved in the recognition, sequestration, and transport events has begun to provide information about this important area of eukaryotic cell physiology.
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Cites
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Cited by
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Self-citationA ubiquitin-like system mediates protein lipidation
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Self-citationULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
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Metadata
- Authors
- Klionsky, D. J., & Ohsumi, Y.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 1999-11
- Volume
- 15
- Issue
- 1
- Pages
- 1-32
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2137690550
- Cited by
- 465
- References
- 81
- FWCI
- 1.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Klionsky, D. J., & Ohsumi, Y. (1999). Vacuolar Import of Proteins and Organelles From The Cytoplasm. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.15.1.1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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