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Cited by 1,285

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Molecular Regulation of Adipogenesis

Rosen, Evan D., Spiegelman, Bruce M.·2000·Annual Review of Cell and Developmental Biology

Abstract

▪ Abstract Adipogenesis, or the development of fat cells from preadipocytes, has been one of the most intensely studied models of cellular differentiation. In part this has been because of the availability of in vitro models that faithfully recapitulate most of the critical aspects of fat cell formation in vivo. More recently, studies of adipogenesis have proceeded with the hope that manipulation of this process in humans might one day lead to a reduction in the burden of obesity and diabetes. This review explores some of the highlights of a large and burgeoning literature devoted to understanding adipogenesis at the molecular level. The hormonal and transcriptional control of adipogenesis is reviewed, as well as studies on a less well known type of fat cell, the brown adipocyte. Emphasis is placed, where possible, on in vivo studies with the hope that the results discussed may one day shed light on basic questions of cellular growth and differentiation in addition to possible benefits in human health.

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Crossref · 10.1146/annurev.cellbio.16.1.145

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Metadata

Authors
Rosen, E. D., & Spiegelman, B. M.
Venue
Annual Review of Cell and Developmental Biology
Published
2000-11
Volume
16
Issue
1
Pages
145-171
ISSN
  • 1081-0706 (ISSN-L)
  • 1530-8995
OpenAlex
W2097899015
Cited by
1,285
References
17
FWCI
4.14
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Molecular Regulation of Adipogenesis. https://app.cochat.ai/papers/10.1146/annurev.cellbio.16.1.145
The paper
Rosen, E. D., & Spiegelman, B. M. (2000). Molecular Regulation of Adipogenesis. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.16.1.145

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.