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Cited by 637

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles

Brodsky, Frances M., Chen, Chih-Ying, Knuehl, Christine, Towler, Mhairi C., Wakeham, Diane E.·2001·Annual Review of Cell and Developmental Biology

Abstract

▪ Abstract There has recently been considerable progress in understanding the regulation of clathrin-coated vesicle (CCV) formation and function. These advances are due to the determination of the structure of a number of CCV coat components at molecular resolution and the identification of novel regulatory proteins that control CCV formation in the cell. In addition, pathways of (a) phosphorylation, (b) receptor signaling, and (c) lipid modification that influence CCV formation, as well as the interaction between the cytoskeleton and CCV transport pathways are becoming better defined. It is evident that although clathrin coat assembly drives CCV formation, this fundamental reaction is modified by different regulatory proteins, depending on where CCVs are forming in the cell. This regulatory difference likely reflects the distinct biological roles of CCVs at the plasma membrane and trans-Golgi network, as well as the distinct properties of these membranes themselves. Tissue-specific functions of CCVs require even more-specialized regulation and defects in these pathways can now be correlated with human diseases.

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Crossref · 10.1146/annurev.cellbio.17.1.517

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Metadata

Authors
Brodsky, F. M., Chen, C.-Y., Knuehl, C., Towler, M. C., & Wakeham, D. E.
Venue
Annual Review of Cell and Developmental Biology
Published
2001-11
Volume
17
Issue
1
Pages
517-568
ISSN
  • 1081-0706 (ISSN-L)
  • 1530-8995
OpenAlex
W2145333947
Cited by
637
References
6
FWCI
2.47
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.