The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
PLANAR CELL POLARIZATION: An Emerging Model Points in the Right Direction
Abstract
Polarization is a feature common to many cell types. Epithelial cells, for example, exhibit a characteristic apical-basolateral polarity that is critical for their function. In addition to this ubiquitous form of polarity, whole fields of cells are often polarized in a plane perpendicular to the apical-basal axis. This form of polarity, referred to as planar cell polarity (PCP), exists in all adult Drosophila cuticular tissues, as well as in numerous vertebrate tissues, including the mammalian skin and inner ear epithelia. Recent advances in the study of PCP establishment are beginning to unravel the molecular mechanisms underlying this cellular process. This review discusses new developments in the molecular understanding of PCP in Drosophila and vertebrates and integrates the current data in a model to illustrate how interactions between PCP factors might function to generate planar polarity.
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Cites
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Self-citationDishevelled controls cell polarity during Xenopus gastrulation
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Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements
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Cited by
When cilia go bad: cilia defects and ciliopathies
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Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development
Morrisey, E. E., & Hogan, B. L. M. (2010) · Developmental Cell · doi:10.1016/j.devcel.2009.12.010 · Cited by 964
Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein
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Principles of planar polarity in animal development
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Planar Cell Polarity Signaling: From Fly Development to Human Disease
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Self-citation
Metadata
- Authors
- Klein, T. J., & Mlodzik, M.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2005-11-01
- Volume
- 21
- Issue
- 1
- Pages
- 155-176
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2146826296
- Cited by
- 314
- References
- 12
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Klein, T. J., & Mlodzik, M. (2005). PLANAR CELL POLARIZATION: An Emerging Model Points in the Right Direction. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.21.012704.132806
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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