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Cited by 484

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

The Role of Pax Genes in the Development of Tissues and Organs:Pax3 and Pax7 Regulate Muscle Progenitor Cell Functions

Buckingham, Margaret, Relaix, Frédéric·2007·Annual Review of Cell and Developmental Biology

Abstract

Pax genes play key roles in the formation of tissues and organs during embryogenesis. Pax3 and Pax7 mark myogenic progenitor cells and regulate their behavior and their entry into the program of skeletal muscle differentiation. Recent results have underlined the importance of the Pax3/7 population of cells for skeletal muscle development and regeneration. We present our current understanding of different aspects of Pax3/7 function in myogenesis, focusing on the mouse model. This is compared with that of other Pax proteins in the emergence of tissue specific lineages and their differentiation as well as in cell survival, proliferation, and migration. Finally, we consider the molecular mechanisms that underlie the function of Pax transcription factors, including the cofactors and regulatory networks with which they interact.

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Crossref · 10.1146/annurev.cellbio.23.090506.123438

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Metadata

Authors
Buckingham, M., & Relaix, F.
Venue
Annual Review of Cell and Developmental Biology
Published
2007-11-01
Volume
23
Issue
1
Pages
645-673
ISSN
  • 1081-0706 (ISSN-L)
  • 1530-8995
OpenAlex
W2127314696
Cited by
484
References
6
FWCI
1.68
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Role of Pax Genes in the Development of Tissues and Organs:Pax3 and Pax7 Regulate Muscle Progenitor Cell Functions. https://app.cochat.ai/papers/10.1146/annurev.cellbio.23.090506.123438
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Buckingham, M., & Relaix, F. (2007). The Role of Pax Genes in the Development of Tissues and Organs:Pax3 and Pax7 Regulate Muscle Progenitor Cell Functions. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.23.090506.123438

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.