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GENE AMPLIFICATION AND GENOMIC PLASTICITY IN PROKARYOTES
Abstract
▪ Abstract Gene amplification is a common feature of the genome of prokaryotic organisms. In this review, we analyze different instances of gene amplification in a variety of prokaryotes, including their mechanisms of generation and biological role. Growing evidence supports the concept that gene amplification be considered not as a mutation but rather as a dynamic genomic state related to the adaptation of bacterial populations to changing environmental conditions or biological interactions. In this context, the potentially amplifiable DNA regions impose a defined dynamic structure on the genome. If such structure has indeed been selected during evolution, it is a particularly challenging hypothesis.
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Citations
Cited by
The evolution of gene duplications: classifying and distinguishing between models
Innan, H., & Kondrashov, F. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2689 · Cited by 1,307
Turning a hobby into a job: How duplicated genes find new functions
Conant, G. C., & Wolfe, K. H. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2482 · Cited by 1,281
Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae
Dunham, M. J., Badrane, H., Ferea, T., Adams, J., Brown, P. O., Rosenzweig, F., & Botstein, D. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242624799 · Cited by 564
Horizontal Transfer, Not Duplication, Drives the Expansion of Protein Families in Prokaryotes
Treangen, T. J., & Rocha, E. P. C. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1001284 · Cited by 509
“Duplication processes in prokaryotes produce tandem, strictly identical copies of genes [8,38,39].”
BackgroundOhno's dilemma: Evolution of new genes under continuous selection
Bergthorsson, U., Andersson, D. I., & Roth, J. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707158104 · Cited by 405
Metadata
- Authors
- Romero, D., & Palacios, R.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 1997-12
- Volume
- 31
- Issue
- 1
- Pages
- 91-111
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2140029549
- Cited by
- 237
- References
- 0
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: GENE AMPLIFICATION AND GENOMIC PLASTICITY IN PROKARYOTES. https://app.cochat.ai/papers/10.1146/annurev.genet.31.1.91
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- Romero, D., & Palacios, R. (1997). GENE AMPLIFICATION AND GENOMIC PLASTICITY IN PROKARYOTES. Annual Review of Genetics. https://doi.org/10.1146/annurev.genet.31.1.91
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
