The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.
Mitochondrial Morphology and Dynamics in Yeast and Multicellular Eukaryotes
Abstract
Mitochondria form dynamic tubular networks that continually change their shape and move throughout the cell. In eukaryotes, these organellar gymnastics are controlled by numerous pathways that preserve proper mitochondrial morphology and function. The best understood of these are the fusion and fission pathways, which rely on conserved GTPases and their binding partners to regulate organelle connectivity and copy number in healthy cells and during apoptosis. In budding yeast, mitochondrial shape is also maintained by proteins acting in the tubulation pathway. Novel proteins and pathways that control mitochondrial dynamics continue to be discovered, indicating that the mechanisms governing this organelle's behavior are more sophisticated than previously appreciated. Here we review recent advances in the field of mitochondrial dynamics and highlight the importance of these pathways to human health.
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Cites
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Cited by
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082
Mitochondrial fusion and fission in cell life and death
Westermann, B. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3013 · Cited by 2,002
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
Chan, D. C. (2006) · Cell · doi:10.1016/j.cell.2006.06.010 · Cited by 1,987
Mitochondria: More Than Just a Powerhouse
McBride, H. M., Neuspiel, M., & Wasiak, S. (2006) · Current Biology · doi:10.1016/j.cub.2006.06.054 · Cited by 1,985
The pathways of mitophagy for quality control and clearance of mitochondria
Ashrafi, G., & Schwarz, T. L. (2013) · Cell Death & Differentiation · doi:10.1038/cdd.2012.81 · Cited by 1,900
Metadata
- Authors
- Okamoto, K., & Shaw, J. M.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 2005-12-01
- Volume
- 39
- Issue
- 1
- Pages
- 503-536
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2157299674
- Cited by
- 747
- References
- 159
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Okamoto, K., & Shaw, J. M. (2005). Mitochondrial Morphology and Dynamics in Yeast and Multicellular Eukaryotes. Annual Review of Genetics. https://doi.org/10.1146/annurev.genet.38.072902.093019
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
