The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.
INITIATION AND PROCESSING OF SIGNALS FROM THE B CELL ANTIGEN RECEPTOR
Abstract
Current models of signal transduction from the antigen receptors on B and T cells still resemble equations with several unknown elements. Data from recent knock-out experiments in cell lines and mice contradict the assumption that Src-family kinase and tyrosine kinases of the Syk/Zap-70 family are the transducer elements that set signaling from these receptors in motion. Using a functional definition of signaling elements, we discuss the current knowledge of signaling events from the BCR and suggest the existence of an as-yet-unknown BCR transducer complex.
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Cites
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SH2 domains recognize specific phosphopeptide sequences
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Protein modules and signalling networks
Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420
Clonal selection and learning in the antibody system
Rajewsky, K. (1996) · Nature · doi:10.1038/381751a0 · Cited by 1,709
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Self-citationIhle, J. N. (1995) · Nature · doi:10.1038/377591a0 · Cited by 1,203
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain
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MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
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Cited by
Shaffer, A. L., Lin, K.-I., Kuo, T. C., Yu, X., Hurt, E. M., Rosenwald, A., Giltnane, J. M., Yang, L., Zhao, H., Calame, K., et al. (2002) · Immunity · doi:10.1016/s1074-7613(02)00335-7 · Cited by 1,047
Testing gene function early in the B cell lineage in mb1-cre mice
Hobeika, E., Thiemann, S., Storch, B., Jumaa, H., Nielsen, P. J., Pelanda, R., & Reth, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605944103 · Cited by 579
Self-citationSurvival of Resting Mature B Lymphocytes Depends on BCR Signaling via the Igα/β Heterodimer
Kraus, M., Alimzhanov, M. B., Rajewsky, N., & Rajewsky, K. (2004) · Cell · doi:10.1016/j.cell.2004.05.014 · Cited by 572
Fu (1998) · doi:10.1016/s1074-7613(00)80591-9 · Cited by 518
Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors
Wang, D., Feng, J., Wen, R., Marine, J.-C., Sangster, M. Y., Parganas, E., Hoffmeyer, A., Jackson, C. W., Cleveland, J. L., Murray, P. J., et al. (2000) · Immunity · doi:10.1016/s1074-7613(00)00005-4 · Cited by 475
Metadata
- Authors
- Reth, M., & Wienands, J.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1997-04
- Volume
- 15
- Issue
- 1
- Pages
- 453-479
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2134505654
- Cited by
- 437
- References
- 126
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: INITIATION AND PROCESSING OF SIGNALS FROM THE B CELL ANTIGEN RECEPTOR. https://app.cochat.ai/papers/10.1146/annurev.immunol.15.1.453
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- Reth, M., & Wienands, J. (1997). INITIATION AND PROCESSING OF SIGNALS FROM THE B CELL ANTIGEN RECEPTOR. Annual Review of Immunology. https://doi.org/10.1146/annurev.immunol.15.1.453
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
