The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling
Open accessAbstract
▪ Abstract During the last several years, the mechanism of IFNγ-dependent signal transduction has been the focus of intense investigation. This research has recently culminated in the elucidation of a comprehensive molecular understanding of the events that underlie IFNγ-induced cellular responses. The structure and function of the IFNγ receptor have been defined. The mechanism of IFNγ signal transduction has been largely elucidated, and the physiologic relevance of this process validated. Most recently, the molecular events that link receptor ligation to signal transduction have been established. Together these insights have produced a model of IFNγ signaling that is nearly complete and that serves as a paradigm for signaling by other members of the cytokine receptor superfamily.
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Essential role of Stat6 in IL-4 signalling
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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
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Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
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Ligand-Induced Assembly and Activation of the Gamma Interferon Receptor in Intact Cells
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Cancer immunotherapy using checkpoint blockade
Ribas, A., & Wolchok, J. D. (2018) · Science · doi:10.1126/science.aar4060 · Cited by 6,791
Interleukin-10 and the Interleukin-10 Receptor
Moore, K. W., de Waal Malefyt, R., Coffman, R. L., & O'Garra, A. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.683 · Cited by 6,737
Alternative activation of macrophages
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Interferon-γ: an overview of signals, mechanisms and functions
Schroder, K., Hertzog, P. J., Ravasi, T., & Hume, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0603252 · Cited by 4,120
HOW CELLS RESPOND TO INTERFERONS
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Metadata
- Authors
- Bach, E. A., Aguet, M., & Schreiber, R. D.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1997-04
- Volume
- 15
- Issue
- 1
- Pages
- 563-591
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2153398168
- Cited by
- 1,034
- References
- 9
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Bach, E. A., Aguet, M., & Schreiber, R. D. (1997). THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling. Annual Review of Immunology. https://doi.org/10.1146/annurev.immunol.15.1.563
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
