HOW CELLS RESPOND TO INTERFERONS

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Functional diversity of helper T lymphocytes

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NITRIC OXIDE AND MACROPHAGE FUNCTION

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STATs and Gene Regulation

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Virus interference. I. the interferon

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Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by <i>Listeria</i> -Induced Macrophages

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CELLULAR RESPONSES TO INTERFERON-γ

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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A family of cytokine-inducible inhibitors of signalling

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Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

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Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

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INTERFERONS AND THEIR ACTIONS

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TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

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Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

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Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

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The Cell Biology of Macrophage Activation

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Immune Response in Mice that Lack the Interferon-γ Receptor

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Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

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A new protein containing an SH2 domain that inhibits JAK kinases

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STATs: Signal Transducers and Activators of Transcription

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Interleukin-6 family of cytokines and gp130.

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The Molecular Cell Biology of Interferon-gamma and its Receptor

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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Structure and function of a new STAT-induced STAT inhibitor

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Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

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A Mutation in the Interferon-γ –Receptor Gene and Susceptibility to Mycobacterial Infection

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Identification and Characterization of an IκB Kinase

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Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

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THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme

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Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

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Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

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Jaks and Stats in signaling by the cytokine receptor superfamily.

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The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response

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Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV

Moore, P. S., Boshoff, C., Weiss, R. A., & Chang, Y. (1996) · Science · doi:10.1126/science.274.5293.1739 · Cited by 900 · see citing works

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

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Interferon-γ –Receptor Deficiency in an Infant with Fatal Bacille Calmette–Guérin Infection

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Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages

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Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

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Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

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Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein

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Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

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A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

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Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

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pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

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Interleukin 6 and its receptor: ten years later

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Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein.

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Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

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Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

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Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

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The human interferon $alpha;/$beta; receptor: Characterization and molecular cloning

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Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

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Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

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Defective Lymphoid Development in Mice Lacking Jak3

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Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.

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ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX

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Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.

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Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.Preprint

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Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

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Interferon action and apoptosis are defective in mice devoid of 2′,5′‐oligoadenylate‐dependent RNase L

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Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

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Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

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A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain.Preprint

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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

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Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action

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Defective TNF-α-Induced Apoptosis in STAT1-Null Cells Due to Low Constitutive Levels of Caspases

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Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α

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Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species soecificity

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REGULATION OF MHC CLASS II GENES: Lessons from a Disease

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Two contact regions between Stat1 and CBP/p300 in interferon γ signaling

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Regulation of Interleukin 12 p40 Expression through an NF-κB Half-Site

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Cooperative DNA Binding and Sequence-Selective Recognition Conferred by the STAT Amino-Terminal Domain

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Cathepsin D protease mediates programmed cell death induced by interferon‐gamma, Fas/APO‐1 and TNF‐alpha.

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Ligand‐induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

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Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.

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GAS Elements: A Few Nucleotides with a Major Impact on Cytokine-Induced Gene Expression

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An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.

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Contribution of STAT SH2 Groups to Specific Interferon Signaling by the Jak-STAT pathway

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Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300

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Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

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DAP‐kinase is a Ca2+/calmodulin‐dependent, cytoskeletal‐associated protein kinase, with cell death‐inducing functions that depend on its catalytic activity

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Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways.

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Regulation of Interferon-γ-Activated STAT1 by the Ubiquitin-Proteasome Pathway

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DAP kinase links the control of apoptosis to metastasis

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