Regulation of the immune response by the aryl hydrocarbon receptor

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

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IL-17 and th17 cells

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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

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A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

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Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22

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2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

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Antigen presentation and T cell stimulation by dendritic cells.

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Reciprocal T _H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

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IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells

Korn, T., Bettelli, E., Gao, W., Awasthi, A., Jäger, A., Strom, T. B., Oukka, M., & Kuchroo, V. K. (2007) · Nature · doi:10.1038/nature05970 · Cited by 1,841 · see citing works

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

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An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

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TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

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Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

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Induction and molecular signature of pathogenic TH17 cells

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Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

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Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin-Binding Ah Receptor

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

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Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

Boitano, A. E., Wang, J., Romeo, R., Bouchez, L. C., Parker, A. E., Sutton, S., Walker, J., Flaveny, C. A., Perdew, G., Denison, M., et al. (2010) · Science · doi:10.1126/science.1191536 · Cited by 1,058 · see citing works

The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

Fallarino, F., Grohmann, U., You, S., McGrath, B. C., Cavener, D. R., Vacca, C., Orabona, C., Bianchi, R., Belladonna, M. L., Volpi, C., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.11.6752 · Cited by 1,042 · see citing works

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

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Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.

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Treg cells expressing the co-inhibitory molecule TIGIT selectively inhibit pro-inflammatory Th1 and Th17 cell responses

Joller, N., Lozano, E., Burkett, P. R., Patel, B., Xiao, S., Zhu, C., Xia, J., Tan, T.-G., Sefik, E., Yajnik, V., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.02.012 · Cited by 904 · see citing works

<i>Lactobacillus reuteri</i> induces gut intraepithelial CD4 ⁺ CD8αα ⁺ T cells

Cervantes-Barragan, L., Chai, J. N., Tianero, M. D., Di Luccia, B., Ahern, P. P., Merriman, J., Cortez, V. S., Caparon, M. G., Donia, M. S., Gilfillan, S., et al. (2017) · Science · doi:10.1126/science.aah5825 · Cited by 896 · see citing works

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

Qiu, J., Heller, J. J., Guo, X.-H., Chen, Z.-M. E., Fish, K., Fu, Y.-X., & Zhou, L. (2011) · Immunity · doi:10.1016/j.immuni.2011.11.011 · Cited by 850 · see citing works

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

Li, Y., Innocentin, S., Withers, D. R., Roberts, N. A., Gallagher, A., Grigorieva, E. F., Wilhelm, C., & Veldhoen, M. (2011) · Cell · doi:10.1016/j.cell.2011.09.025 · Cited by 822 · see citing works

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells

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Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

Korn, T., Reddy, J., Gao, W., Bettelli, E., Awasthi, A., Petersen, T. R., Bäckström, B. T., Sobel, R. A., Wucherpfennig, K. W., Strom, T. B., et al. (2007) · Nature Medicine · doi:10.1038/nm1564 · Cited by 812 · see citing works

A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells

Awasthi, A., Carrier, Y., Peron, J. P. S., Bettelli, E., Kamanaka, M., Flavell, R. A., Kuchroo, V. K., Oukka, M., & Weiner, H. L. (2007) · Nature Immunology · doi:10.1038/ni1541 · Cited by 804 · see citing works

Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

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Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

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Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

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The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

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Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

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Aryl hydrocarbon receptor control of a disease tolerance defence pathway

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Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10

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The mammalian basic helix–loop–helix/PAS family of transcriptional regulators

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Identification of a novel mechanism of regulation of Ah (dioxin) receptor functionPreprint

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Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

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Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

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The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

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Feedback control of AHR signalling regulates intestinal immunity

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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

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Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

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Association of the Ah receptor with the 90-kDa heat shock protein.

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γδ T Cells and the Lymphoid Stress-Surveillance Response

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Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

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Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

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Th22 Cells are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria

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Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

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An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

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Ligand-dependent Interaction of the Aryl Hydrocarbon Receptor with a Novel Immunophilin Homolog in Vivo*

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Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

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Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

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Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine

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Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells

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IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

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Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

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