The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
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“Th1 cells produce large quantities of interferon-γ, induce delayed hypersensitivity reactions, activate macrophages, and are essential for defense against intracellular pathogens.”
From Cytokine storm (2020) · cites this paper as [19]
Citations
Cites
Mosmann, T. R., Cherwinski, H. M., Bond, M. W., Giedlin, M. A., & Coffman, R. L. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.7.2348 · Cited by 7,553
Self-citationInterferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production
Snapper, C. M., & Paul, W. E. (1987) · Science · doi:10.1126/science.3107127 · Cited by 1,927
Cherwinski, H., Schumacher, J., Brown, K., & Mosmann, T. (1987) · Journal of Experimental Medicine · doi:10.1084/jem.166.5.1229 · Cited by 1,118
Self-citationCantor, H., & Boyse, E. A. (1975) · The Journal of Experimental Medicine · doi:10.1084/jem.141.6.1376 · Cited by 1,106
Cher, D., & Mosmann, T. R. (1987) · The Journal of Immunology · doi:10.4049/jimmunol.138.11.3688 · Cited by 960
Self-citationRegulation of antibody isotype secretion by subsets of antigen-specific helper T cells
Stevens, T. L., Bossie, A., Sanders, V. M., Fernandez-Botran, R., Coffman, R. L., Mosmann, T. R., & Vitetta, E. S. (1988) · Nature · doi:10.1038/334255a0 · Cited by 933
Self-citationThe isolation and characterization of the human suppressor inducer T cell subset.
Morimoto, C., Letvin, N. L., Distaso, J. A., Aldrich, W. R., & Schlossman, S. F. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.134.3.1508 · Cited by 848
Gajewski, T. F., & Fitch, F. W. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.140.12.4245 · Cited by 839
Two types of mouse helper T-cell clone Implications for immune regulation.
Mosmann, T., & Coffman, R. (1987) · Immunology today (Amsterdam. Regular ed.) · doi:10.1016/0167-5699(87)90171-x · Cited by 826
Self-citationB cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.
Coffman, R. L., Ohara, J., Bond, M. W., Carty, J., Zlotnik, A., & Paul, W. E. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.12.4538 · Cited by 796
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Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992
Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873
Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., & Weaver, C. T. (2005) · Nature Immunology · doi:10.1038/ni1254 · Cited by 4,742
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G., & Glimcher, L. H. (2000) · Cell · doi:10.1016/s0092-8674(00)80702-3 · Cited by 3,589
Metadata
- Authors
- Mosmann, T. R., & Coffman, R. L.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1989-04
- Volume
- 7
- Issue
- 1
- Pages
- 145-173
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2172466148
- Cited by
- 7,692
- References
- 103
- Citations by year
- 2026: 43 · 2025: 73 · 2024: 90 · 2023: 70 · 2022: 73 · 2021: 112 · 2020: 109 · 2019: 102 · 2018: 124 · 2017: 142 · 2016: 147 · 2015: 161 · 2014: 198 · 2013: 208 · 2012: 228
- FWCI
- 60.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Keywords
- Th1 cells, Th2 cells, lymphokine secretion, T helper cell function, CD8+ T cell exhaustion, inhibitory receptors, chronic infection, tumor immunology
- MeSH terms
- Animals, Antibody Formation, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Lymphokines, Mice
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