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TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
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“Th1 cells produce large quantities of interferon-γ, induce delayed hypersensitivity reactions, activate macrophages, and are essential for defense against intracellular pathogens.”
From Cytokine storm (2020) · cites this paper as [19]
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Mosmann, T. R., Cherwinski, H. M., Bond, M. W., Giedlin, M. A., & Coffman, R. L. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.7.2348 · Cited by 7,553
Self-citationInterferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production
Snapper, C. M., & Paul, W. E. (1987) · Science · doi:10.1126/science.3107127 · Cited by 1,927
Cherwinski, H., Schumacher, J., Brown, K., & Mosmann, T. (1987) · Journal of Experimental Medicine · doi:10.1084/jem.166.5.1229 · Cited by 1,118
Self-citationCantor, H., & Boyse, E. A. (1975) · The Journal of Experimental Medicine · doi:10.1084/jem.141.6.1376 · Cited by 1,106
Cher, D., & Mosmann, T. R. (1987) · The Journal of Immunology · doi:10.4049/jimmunol.138.11.3688 · Cited by 960
Self-citationRegulation of antibody isotype secretion by subsets of antigen-specific helper T cells
Stevens, T. L., Bossie, A., Sanders, V. M., Fernandez-Botran, R., Coffman, R. L., Mosmann, T. R., & Vitetta, E. S. (1988) · Nature · doi:10.1038/334255a0 · Cited by 933
Self-citationThe isolation and characterization of the human suppressor inducer T cell subset.
Morimoto, C., Letvin, N. L., Distaso, J. A., Aldrich, W. R., & Schlossman, S. F. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.134.3.1508 · Cited by 848
Gajewski, T. F., & Fitch, F. W. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.140.12.4245 · Cited by 839
Two types of mouse helper T-cell clone Implications for immune regulation.
Mosmann, T., & Coffman, R. (1987) · Immunology today (Amsterdam. Regular ed.) · doi:10.1016/0167-5699(87)90171-x · Cited by 826
Self-citationB cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.
Coffman, R. L., Ohara, J., Bond, M. W., Carty, J., Zlotnik, A., & Paul, W. E. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.12.4538 · Cited by 796
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Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873
Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., & Weaver, C. T. (2005) · Nature Immunology · doi:10.1038/ni1254 · Cited by 4,742
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Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G., & Glimcher, L. H. (2000) · Cell · doi:10.1016/s0092-8674(00)80702-3 · Cited by 3,589
Macrophage activation and polarization
Martinez, F. O. (2008) · Frontiers in Bioscience · doi:10.2741/2692 · Cited by 3,160
Targan, S. R., Hanauer, S. B., van Deventer, S. J. H., Mayer, L., Present, D. H., Braakman, T., DeWoody, K. L., Schaible, T. F., & Rutgeerts, P. J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199710093371502 · Cited by 3,135
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Hsieh, C.-S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., & Murphy, K. M. (1993) · Science · doi:10.1126/science.8097338 · Cited by 3,134
Fajgenbaum, D. C., & June, C. H. (2020) · New England Journal of Medicine · doi:10.1056/nejmra2026131 · Cited by 3,196
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Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
Bethony, J., Brooker, S., Albonico, M., Geiger, S. M., Loukas, A., Diemert, D., & Hotez, P. J. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68653-4 · Cited by 2,478
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Zhu, C., Anderson, A. C., Schubart, A., Xiong, H., Imitola, J., Khoury, S. J., Zheng, X. X., Strom, T. B., & Kuchroo, V. K. (2005) · Nature Immunology · doi:10.1038/ni1271 · Cited by 2,057
A cell culture model for T lymphocyte clonal anergy
Schwartz, R. H. (1990) · Science · doi:10.1126/science.2113314 · Cited by 1,857
IL-17 family cytokines and the expanding diversity of effector T cell lineages
Weaver, C. T., Hatton, R. D., Mangan, P. R., & Harrington, L. E. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141557 · Cited by 1,842
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing
Gaffen, S. L., Jain, R., Garg, A. V., & Cua, D. J. (2014) · Nature reviews. Immunology · doi:10.1038/nri3707 · Cited by 1,585
Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
Laurence, A., Tato, C. M., Davidson, T. S., Kanno, Y., Chen, Z., Yao, Z., Blank, R. B., Meylan, F., Siegel, R., Hennighausen, L., et al. (2007) · Immunity · doi:10.1016/j.immuni.2007.02.009 · Cited by 1,507
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M., & Murphy, K. M. (2006) · Immunity · doi:10.1016/j.immuni.2006.06.002 · Cited by 1,422
Interleukin-17 and Type 17 Helper T Cells
Miossec, P., Korn, T., & Kuchroo, V. K. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0707449 · Cited by 1,409
Ito, T., Wang, Y.-H., Duramad, O., Hori, T., Delespesse, G. J., Watanabe, N., Qin, F. X.-F., Yao, Z., Cao, W., & Liu, Y.-J. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20051135 · Cited by 1,129
Proinflammatory Cytokines, Aging, and Age-Related Diseases
Michaud, M., Balardy, L., Moulis, G., Gaudin, C., Peyrot, C., Vellas, B., Cesari, M., & Nourhashemi, F. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.009 · Cited by 1,094
Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells
Sallusto, F., Mackay, C. R., & Lanzavecchia, A. (1997) · Science · doi:10.1126/science.277.5334.2005 · Cited by 1,050
TH17 cells in development: an updated view of their molecular identity and genetic programming
Dong, C. (2008) · Nature reviews. Immunology · doi:10.1038/nri2295 · Cited by 1,064
The pig: a model for human infectious diseases
Meurens, F., Summerfield, A., Nauwynck, H., Saif, L., & Gerdts, V. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2011.11.002 · Cited by 999
Le Gros, G., Ben-Sasson, S. Z., Seder, R., Finkelman, F. D., & Paul, W. E. (1990) · The Journal of experimental medicine · doi:10.1084/jem.172.3.921 · Cited by 954
Fidel, P. L., Vazquez, J. A., & Sobel, J. D. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.1.80 · Cited by 953
Stumhofer, J. S., Laurence, A., Wilson, E. H., Huang, E., Tato, C. M., Johnson, L. M., Villarino, A. V., Huang, Q., Yoshimura, A., Sehy, D., et al. (2006) · Nature Immunology · doi:10.1038/ni1376 · Cited by 955
γδ T cell effector functions: a blend of innate programming and acquired plasticity
Bonneville, M., O'Brien, R. L., & Born, W. K. (2010) · Nature Reviews Immunology · doi:10.1038/nri2781 · Cited by 952
Volpe, E., Servant, N., Zollinger, R., Bogiatzi, S. I., Hupé, P., Barillot, E., & Soumelis, V. (2008) · Nature Immunology · doi:10.1038/ni.1613 · Cited by 938
Dhabhar, F. S. (2009) · Neuroimmunomodulation · doi:10.1159/000216188 · Cited by 903
Nitric oxide in health and disease of the respiratory system
Ricciardolo, F. L. M., Sterk, P. J., Gaston, B., & Folkerts, G. (2004) · Physiological Reviews · doi:10.1152/physrev.00034.2003 · Cited by 903
McEwen, B. S., Biron, C. A., Brunson, K. W., Bulloch, K., Chambers, W. H., Dhabhar, F. S., Goldfarb, R. H., Kitson, R. P., Miller, A. H., Spencer, R. L., et al. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(96)00012-4 · Cited by 837
Cytokines and the Brain: Implications for Clinical Psychiatry
Kronfol, Z., & Remick, D. G. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.683 · Cited by 784
Interleukin-12: A Cytokine at the Interface of Inflammation and Immunity
Trinchieri, G. (1998) · Advances in Immunology · doi:10.1016/s0065-2776(08)60387-9 · Cited by 760
Ferrick, D. A., Schrenzel, M. D., Mulvania, T., Hsieh, B., Ferlin, W. G., & Lepper, H. (1995) · Nature · doi:10.1038/373255a0 · Cited by 662
Elaborate interactions between the immune and nervous systems
Steinman, L. (2004) · Nature Immunology · doi:10.1038/ni1078 · Cited by 556
Modolell, M., Corraliza, I. M., Link, F., Soler, G., & Eichmann, K. (1995) · European Journal of Immunology · doi:10.1002/eji.1830250436 · Cited by 554
Mizuhara, H., O'Neill, E., Seki, N., Ogawa, T., Kusunoki, C., Otsuka, K., Satoh, S., Niwa, M., Senoh, H., & Fujiwara, H. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.5.1529 · Cited by 517
The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
Weaver, C. T., Elson, C. O., Fouser, L. A., & Kolls, J. K. (2013) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130318 · Cited by 462
The IL-23-IL-17 axis in inflammatory arthritis
Lubberts, E. (2015) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2015.53 · Cited by 442
The role of IL-6 in host defence against infections: immunobiology and clinical implications
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Screpanti, I., Romani, L., Musiani, P., Modesti, A., Fattori, E., Lazzaro, D., Sellitto, C., Scarpa, S., Bellavia, D., & Lattanzio, G. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07185.x · Cited by 407
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., & Flavell, R. A. (2007) · Immunity · doi:10.1016/j.immuni.2007.05.021 · Cited by 396
Elevated cytokine levels in children with autism spectrum disorder
Molloy, C. A., Morrow, A. L., Meinzen-Derr, J., Schleifer, K., Dienger, K., Manning-Courtney, P., Altaye, M., & Wills-Karp, M. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.11.007 · Cited by 386
The TIM gene family: emerging roles in immunity and disease
Kuchroo, V. K., Umetsu, D. T., DeKruyff, R. H., & Freeman, G. J. (2003) · Nature Reviews Immunology · doi:10.1038/nri1111 · Cited by 388
Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
Li, C., Xu, X., Wei, S., Jiang, P., Xue, L., & Wang, J. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-001341 · Cited by 360
Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1
Taki, S., Sato, T., Ogasawara, K., Fukuda, T., Sato, M., Hida, S., Suzuki, G., Mitsuyama, M., Shin, E.-H., Kojima, S., et al. (1997) · Immunity · doi:10.1016/s1074-7613(00)80443-4 · Cited by 353
Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity
Sallusto, F., & Lanzavecchia, A. (2009) · European Journal of Immunology · doi:10.1002/eji.200939722 · Cited by 348
Beck, F. W., Prasad, A. S., Kaplan, J., Fitzgerald, J. T., & Brewer, G. J. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.6.e1002 · Cited by 345
Iron and immunity: a double-edged sword.
Weiss, G. (2002) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2002.0320s1070.x · Cited by 317
Zinc: Mechanisms of Host Defense1,
Prasad, A. S. (2007) · The Journal of Nutrition · doi:10.1093/jn/137.5.1345 · Cited by 314
Akimzhanov, A. M., Yang, X. O., & Dong, C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.c600322200 · Cited by 302
Human Th1 and Th2 lymphocytes: their role in the pathophysiology of atopy
Prete, G. D. (1992) · Allergy · doi:10.1111/j.1398-9995.1992.tb00662.x · Cited by 287
TH17 cell heterogeneity and its role in tissue inflammation
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Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells.
Suzuki, T., Suzuki, N., Daynes, R. A., & Engleman, E. G. (1991) · Clinical Immunology and Immunopathology · doi:10.1016/s0090-1229(05)80024-8 · Cited by 277
Vitamin A and retinoic acid in T cell-related immunity
Ross, A. C. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.034637 · Cited by 261
VIALLARD, J. F., PELLEGRIN, J. L., RANCHIN, V, SCHAEVERBEKE, T., DEHAIS, J., LONGY-BOURSIER, M., RAGNAUD, J. M., LENG, B., & MOREAU, J. F. (2001) · Clinical and Experimental Immunology · doi:10.1046/j.1365-2249.1999.00766.x · Cited by 247
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Glatigny, S., & Bettelli, E. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a028977 · Cited by 247
Cope, A. P., Londei, M., Chu, N. R., Cohen, S. B., Elliott, M. J., Brennan, F. M., Maini, R. N., & Feldmann, M. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117394 · Cited by 243
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STEIN-STREILEIN, J., & STREILEIN, J. W. (2002) · International Reviews of Immunology · doi:10.1080/08830180212066 · Cited by 218
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Jyonouchi, H., Zhang, L., Gross, M., & Tomita, Y. (1994) · Nutrition and Cancer · doi:10.1080/01635589409514303 · Cited by 183
IL-9 and its receptor are predominantly involved in the pathogenesis of UC
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Stummvoll, G. H., DiPaolo, R. J., Huter, E. N., Davidson, T. S., Glass, D., Ward, J. M., & Shevach, E. M. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.3.1908 · Cited by 170
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Keegan, A. D., Leonard, W. J., & Zhu, J. (2021) · Faculty Reviews · doi:10.12703/r/10-71 · Cited by 154
A hassle a day may keep the doctor away: stress and the augmentation of immune function
Dhabhar, F. S. (2002) · Integrative and Comparative Biology · doi:10.1093/icb/42.3.556 · Cited by 146
Lambert, K. C., Curran, E. M., Judy, B. M., Milligan, G. N., Lubahn, D. B., & Estes, D. M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.9.5716 · Cited by 142
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Thorson, J. A., Smith, K. M., Gomez, F., Naumann, P. W., & Kemp, J. D. (1991) · Cellular Immunology · doi:10.1016/0008-8749(91)90336-a · Cited by 98
Nonnecke, B. J., Foote, M. R., Smith, J. M., Pesch, B. A., & Van Amburgh, M. E. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73965-4 · Cited by 100
Murakami, M., Okuyama, Y., Ogura, H., Asano, S., Arima, Y., Tsuruoka, M., Harada, M., Kanamoto, M., Sawa, Y., Iwakura, Y., et al. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20100900 · Cited by 100
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Mitsdoerffer, M., Kuchroo, V., & Korn, T. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12118 · Cited by 91
Iwasaki, M., Nagata, K., Takano, S., Takahashi, K., Ishii, N., & Ikezawa, Z. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01862.x · Cited by 86
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Jyonouchi, H., Zhang, L., & Tomita, Y. (1993) · Nutrition and Cancer · doi:10.1080/01635589309514258 · Cited by 83
Sagawa, K., Nagatani, K., Komagata, Y., & Yamamoto, K. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21040 · Cited by 83
Bax, M., Kuijf, M. L., Heikema, A. P., van Rijs, W., Bruijns, S. C. M., García-Vallejo, J. J., Crocker, P. R., Jacobs, B. C., van Vliet, S. J., & van Kooyk, Y. (2011) · Infection and Immunity · doi:10.1128/iai.00009-11 · Cited by 82
Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.
Hensley, S. E., Cun, A. S., Giles-Davis, W., Li, Y., Xiang, Z., Lasaro, M. O., Williams, B. R. G., Silverman, R. H., & Ertl, H. C. J. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300024 · Cited by 78
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Tay, B. Q., Wright, Q., Ladwa, R., Perry, C., Leggatt, G., Simpson, F., Wells, J. W., Panizza, B. J., Frazer, I. H., & Cruz, J. L. G. (2021) · Vaccines · doi:10.3390/vaccines9050535 · Cited by 76
Signal transduction and Th17 cell differentiation
O'Shea, J. J., Steward-Tharp, S. M., Laurence, A., Watford, W. T., Wei, L., Adamson, A. S., & Fan, S. (2009) · Microbes and Infection · doi:10.1016/j.micinf.2009.04.007 · Cited by 73
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“, T helper 1 (Th1) cells, Th2 cells, and Th17 cells, which produce IFNγ, IL-4, and IL-17A, respectively (Mosmann and Coffman, 1989; Glimcher and Murphy, 2000; Cua et al., 2003; Harrington et al., 2005; Park et al., 2005; Veldhoen et al., 2006; Zhu et al., 2006; Bettelli et al., 2007; Nishihara et al., 2007) – may init…”
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Metadata
- Authors
- Mosmann, T. R., & Coffman, R. L.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1989-04
- Volume
- 7
- Issue
- 1
- Pages
- 145-173
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2172466148
- Cited by
- 7,692
- References
- 103
- Citations by year
- 2026: 43 · 2025: 73 · 2024: 90 · 2023: 70 · 2022: 73 · 2021: 112 · 2020: 109 · 2019: 102 · 2018: 124 · 2017: 142 · 2016: 147 · 2015: 161 · 2014: 198 · 2013: 208 · 2012: 228
- FWCI
- 60.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Keywords
- Th1 cells, Th2 cells, lymphokine secretion, T helper cell function, CD8+ T cell exhaustion, inhibitory receptors, chronic infection, tumor immunology
- MeSH terms
- Animals, Antibody Formation, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Lymphokines, Mice
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