The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Viral Persistence: HIV's Strategies of Immune System Evasion
Abstract
▪ Abstract In contrast to most animal viruses, infection with the human and simian immunodeficiency viruses results in prolonged, continuous viral replication in the infected host. Remarkably, viral persistence is not thwarted by the presence of apparently vigorous, virus-specific immune responses. Several factors are thought to contribute to persistent viral replication, most notably the destruction of virus-specific T helper cells, the emergence of antigenic escape variants, and the expression of an envelope complex that structurally minimizes antibody access to conserved epitopes. Not as well understood, though potentially important, is the ability of at least one viral encoded protein (Nef) to prevent presentation of viral antigens in the context of major histocompatibility complex. The future success of antiviral therapies and vaccination strategies may depend largely on understanding how and to what degree each of these factors (and presumably others) contributes to immune evasion.
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Cites
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
Finzi, D., Hermankova, M., Pierson, T., Carruth, L. M., Buck, C., Chaisson, R. E., Quinn, T. C., Chadwick, K., Margolick, J., Brookmeyer, R., et al. (1997) · Science · doi:10.1126/science.278.5341.1295 · Cited by 3,098
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
Wong, J. K., Hezareh, M., Günthard, H. F., Havlir, D. V., Ignacio, C. C., Spina, C. A., & Richman, D. D. (1997) · Science · doi:10.1126/science.278.5341.1291 · Cited by 2,186
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease
Berger, E. A., Murphy, P. M., & Farber, J. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.657 · Cited by 2,180
Starcich, B. R., Hahn, B. H., Shaw, G. M., McNeely, P. D., Modrow, S., Wolf, H., Parks, E. S., Parks, W. P., Josephs, S. F., Gallo, R. C., et al. (1986) · Cell · doi:10.1016/0092-8674(86)90778-6 · Cited by 767
Cited by
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
Petrovas, C., Casazza, J. P., Brenchley, J. M., Price, D. A., Gostick, E., Adams, W. C., Precopio, M. L., Schacker, T., Roederer, M., Douek, D. C., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061496 · Cited by 889
Hansen, S. G., Vieville, C., Whizin, N., Coyne-Johnson, L., Siess, D. C., Drummond, D. D., Legasse, A. W., Axthelm, M. K., Oswald, K., Trubey, C. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1935 · Cited by 675
Schindler, M., Münch, J., Kutsch, O., Li, H., Santiago, M. L., Bibollet-Ruche, F., Müller-Trutwin, M. C., Novembre, F. J., Peeters, M., Courgnaud, V., et al. (2006) · Cell · doi:10.1016/j.cell.2006.04.033 · Cited by 411
Efficient Targeting of Conserved Cryptic Epitopes of Infectious Agents by Single Domain Antibodies
Stijlemans, B., Conrath, K., Cortez-Retamozo, V., Van Xong, H., Wyns, L., Senter, P., Revets, H., De Baetselier, P., Muyldermans, S., & Magez, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m307341200 · Cited by 276
T Cell Receptor Recognition Motifs Govern Immune Escape Patterns in Acute SIV Infection
Price, D. A., West, S. M., Betts, M. R., Ruff, L. E., Brenchley, J. M., Ambrozak, D. R., Edghill-Smith, Y., Kuroda, M. J., Bogdan, D., Kunstman, K., et al. (2004) · Immunity · doi:10.1016/j.immuni.2004.10.010 · Cited by 272
Metadata
- Authors
- Johnson, W. E., & Desrosiers, R. C.
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 2002-02
- Volume
- 53
- Issue
- 1
- Pages
- 499-518
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2146161844
- Cited by
- 183
- References
- 4
- FWCI
- 1.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Johnson, W. E., & Desrosiers, R. C. (2002). Viral Persistence: HIV's Strategies of Immune System Evasion. Annual Review of Medicine. https://doi.org/10.1146/annurev.med.53.082901.104053
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
