The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Inteins: Structure, Function, and Evolution
Abstract
▪ Abstract Inteins are genetic elements that disrupt the coding sequence of genes. However, in contrast to introns, inteins are transcribed and translated together with their host protein. Inteins appear most frequently in Archaea, but they are found in organisms belonging to all three domains of life and in viral and phage proteins. Most inteins consist of two domains: One is involved in autocatalytic splicing, and the other is an endonuclease that is important in the spread of inteins. This review focuses on the evolution and technical application of inteins and only briefly summarizes recent advances in the study of the catalytic activities and structures of inteins. In particular, this review considers inteins as selfish or parasitic genetic elements, a point of view that explains many otherwise puzzling aspects of inteins.
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Citations
Cites
Quartet Puzzling: A Quartet Maximum-Likelihood Method for Reconstructing Tree Topologies
Strimmer, K., & von Haeseler, A. (1996) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025664 · Cited by 2,531
Production of cyclic peptides and proteins in vivo
Scott, C. P., Abel-Santos, E., Wall, M., Wahnon, D. C., & Benkovic, S. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.24.13638 · Cited by 402
Cited by
Horizontal gene transfer, genome innovation and evolution
Gogarten, J. P., & Townsend, J. P. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1204 · Cited by 1,020
Self-citationXie, H., Vucetic, S., Iakoucheva, L. M., Oldfield, C. J., Dunker, A. K., Obradovic, Z., & Uversky, V. N. (2007) · Journal of Proteome Research · doi:10.1021/pr060394e · Cited by 382
(2006) · doi:10.1007/978-3-540-28398-0 · Cited by 303
Nature's recipe for splitting inteins
Aranko, A. S., Wlodawer, A., & Iwai, H. (2014) · Protein Engineering Design and Selection · doi:10.1093/protein/gzu028 · Cited by 116
Drug Inducible CRISPR/Cas Systems
Zhang, J., Chen, L., Zhang, J., & Wang, Y. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.07.015 · Cited by 69
Metadata
- Authors
- Gogarten, J. P., Senejani, A. G., Zhaxybayeva, O., Olendzenski, L., & Hilario, E.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2002-10
- Volume
- 56
- Issue
- 1
- Pages
- 263-287
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2126528399
- Cited by
- 213
- References
- 2
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gogarten, J. P., Senejani, A. G., Zhaxybayeva, O., Olendzenski, L., & Hilario, E. (2002). Inteins: Structure, Function, and Evolution. Annual Review of Microbiology. https://doi.org/10.1146/annurev.micro.56.012302.160741
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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