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Cited by 356

The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.

Molecular Biology and Pathology of Lymphangiogenesis

Karpanen, Terhi, Alitalo, Kari·2008·Annual Review of Pathology: Mechanisms of Disease

Abstract

The lymphatic vasculature is essential for the maintenance of tissue fluid balance, immune surveillance, and adsorption fatty acids in the gut. The lymphatic vessels are also crucially involved in the pathogenesis of diseases such as tumor metastasis, lymphedema, and various inflammatory conditions. Attempts to control or treat these diseases have drawn a lot of interest to lymphatic vascular research during the past few years. Recently, several markers specific for lymphatic endothelium and models for lymphatic vascular research have been characterized, enabling great technical progress in lymphatic vascular biology, and many critical regulators of lymphatic vessel growth have been identified. Despite these significant achievements, our understanding of the lymphatic vessel development and pathogenesis is still rather limited. Several key questions remain to be resolved, including the relative contributions of different pathways targeting lymphatic vasculature, the molecular and cellular processes of lymphatic maturation, and the detailed mechanisms of tumor metastasis via the lymphatic system.

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Crossref · 10.1146/annurev.pathmechdis.3.121806.151515

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Metadata

Authors
Karpanen, T., & Alitalo, K.
Venue
Annual Review of Pathology: Mechanisms of Disease
Published
2008-02-01
Volume
3
Issue
1
Pages
367-397
ISSN
  • 1553-4006 (ISSN-L)
  • 1553-4014
OpenAlex
W2125621940
Cited by
356
References
143
FWCI
2.15
Type
journal article
Language
en
Open access
closed

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This page
CoChat. (2026). Citation check: Molecular Biology and Pathology of Lymphangiogenesis. https://app.cochat.ai/papers/10.1146/annurev.pathmechdis.3.121806.151515
The paper
Karpanen, T., & Alitalo, K. (2008). Molecular Biology and Pathology of Lymphangiogenesis. Annual Review of Pathology: Mechanisms of Disease. https://doi.org/10.1146/annurev.pathmechdis.3.121806.151515

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.