The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
MicroRNAs in Cancer
Open accessAbstract
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent, and abundant miRNome data are currently available for various cancers. The pattern of miRNA expression can be correlated with cancer type, stage, and other clinical variables, so miRNA profiling can be used as a tool for cancer diagnosis and prognosis. miRNA expression analyses also suggest oncogenic (or tumor-suppressive) roles of miRNAs. miRNAs play roles in almost all aspects of cancer biology, such as proliferation, apoptosis, invasion/metastasis, and angiogenesis. Given that many miRNAs are deregulated in cancers but have not yet been further studied, it is expected that more miRNAs will emerge as players in the etiology and progression of cancer. Here we also discuss miRNAs as a tool for cancer therapy.
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Cites
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Cited by
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Metadata
- Authors
- Lee, Y. S., & Dutta, A.
- Venue
- Annual Review of Pathology: Mechanisms of Disease
- Publisher
- Annual Reviews
- Published
- 2009-02-01
- Volume
- 4
- Issue
- 1
- Pages
- 199-227
- ISSN
- 1553-4006 (ISSN-L)
- 1553-4014
- OpenAlex
- W3146360245
- Cited by
- 1,505
- References
- 28
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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