Gene Therapy with Viral Vectors

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Naldini, L., Blömer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996) · Science · doi:10.1126/science.272.5259.263 · Cited by 4,903

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

Graham, F. L., Russell, W. C., Smiley, J., & Nairn, R. (1977) · Journal of General Virology · doi:10.1099/0022-1317-36-1-59 · Cited by 4,793

A Third-Generation Lentivirus Vector with a Conditional Packaging System

Dull, T., Zufferey, R., Kelly, M., Mandel, R. J., Nguyen, M., Trono, D., & Naldini, L. (1998) · Journal of Virology · doi:10.1128/jvi.72.11.8463-8471.1998 · Cited by 3,341

Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5

Bergelson, J. M., Cunningham, J. A., Droguett, G., Kurt‐Jones, E. A., Krithivas, A., Hong, J. S., Horwitz, M. S., Crowell, R. L., & Finberg, R. W. (1997) · Science · doi:10.1126/science.275.5304.1320 · Cited by 3,102

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Cavazzana, M., Hacein‐Bey‐Abina, S., Basile, G. D. S., Gross, F., Yvon, E. S., Nusbaum, P., Selz, F., Hue, C., Dogniaux, S., Casanova, J., et al. (2000) · Science · doi:10.1126/science.288.5466.669 · Cited by 2,685

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

Wickham, T. J., Mathias, P., Cheresh, D. A., & Nemerow, G. R. (1993) · Cell · doi:10.1016/0092-8674(93)90231-e · Cited by 2,199

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L., & Trono, D. (1997) · Nature Biotechnology · doi:10.1038/nbt0997-871 · Cited by 1,977

Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

Zufferey, R., Dull, T., Mandel, R. J., Bukovsky, A., Quiroz, D., Naldini, L., & Trono, D. (1998) · Journal of Virology · doi:10.1128/jvi.72.12.9873-9880.1998 · Cited by 1,815

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

Mann, R., Mulligan, R. C., & Baltimore, D. (1983) · Cell · doi:10.1016/0092-8674(83)90344-6 · Cited by 1,776

T Lymphocyte-Directed Gene Therapy for ADA − SCID: Initial Trial Results After 4 Years

Blaese, R. M., Culver, K. W., Miller, A. D., Carter, C. S., Fleisher, T. A., Clerici, M., Shearer, G. M., Chang, L., Chiang, Y. L., Tolstoshev, P., et al. (1995) · Science · doi:10.1126/science.270.5235.475 · Cited by 1,546

Gene Therapy and Virus-Based Cancer Vaccines

Salem, M. L., Gadalla, K. K. E., Fielding, B. C., & Thorne, S. H. (2014) · Springer eBooks · doi:10.1007/978-3-662-44946-2_7 · Cited by 3

Selective Microvascular Tissue Transfection Using Minicircle DNA for Systemic Delivery of Human Coagulation Factor IX in a Rat Model Using a Therapeutic Flap

Than, P. A., Davis, C. R., Rennert, R. C., Morrison, S. D., Findlay, M. W., Kay, M. A., & Gurtner, G. C. (2021) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000008630 · Cited by 3

Coexpression of TP53, BIM, and PTEN Enhances the Therapeutic Efficacy of Non-Small-Cell Lung Cancer

Lu, L., Ma, D., & Xi, Z. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.3c00988 · Cited by 3

Plasma-mediated transfection of RPE

Palanker, D., Chalberg, T. W., Vankov, A., Huie, P., Molnar, F. E., Butterwick, A., Calos, M. P., Marmor, M. F., & Blumenkranz, M. S. (2006) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.649624 · Cited by 3

Problems, Side Effects, and Disappointments in Clinical Cancer Gene Therapy

Liu, T., & Kirn, D. H. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-222-9_20 · Cited by 3

Sugar-based systems

Shenoi, R. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-101750-0.00010-6 · Cited by 3

Lentivector Vaccines

Bryson, P. D., & Wang, P. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394295-1.00024-x · Cited by 3

Ultrasound-Mediated Gene TransfectionIn vitro: Enhanced Efficiency by Complexation of Plasmid DNA

Zhang, Y., Tachibana, R., Okamoto, A., Azuma, T., Sasaki, A., Yoshinaka, K., Osada, K., Kataoka, K., Takagi, S., & Matsumoto, Y. (2012) · Japanese Journal of Applied Physics · doi:10.7567/jjap.51.07gf29 · Cited by 3

RNA-based gene therapies for myotonic dystrophy type 1

Langlois, M. (2003) · Cited by 3

Subcloning of NGF Gene into pSecTag2/Hygro Secretory Vector and Expression in PC12 Cell Line

Kondori, B. J., Asadi, M. H., & Azemati, F. (2015) · The Neuroscience Journal of Shefaye Khatam · doi:10.18869/acadpub.shefa.3.1.21 · Cited by 2

Ligand-directed tumor targeting with hybrid viral phage nanoparticles

Dalal, B., Quinn, T. J., Foster, L., Lin, M. I., Matthews, M., & Yuhan, B. T. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813689-8.00013-6 · Cited by 2

Genetics of Hypertension and Cardiovascular Disease

Katsuya, T., Harrap, S. B., & Ogihara, T. (2010) · International Journal of Hypertension · doi:10.4061/2010/951254 · Cited by 2

Applications of Small-Animal Molecular Imaging in Drug Development

Niu, G., & Chen, X. S. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0894-3_24 · Cited by 2

Generation of HIV-1 based bi-cistronic lentiviral vectors for stable gene expression and live cell imaging.

Sehgal, L., Budnar, S., Bhatt, K., Sansare, S., Mukhopadhaya, A., Kalraiya, R. D., & Dalal, S. N. (2012) · PubMed · Cited by 2

Combining Stem Cells and Exon Skipping Strategy to Treat Muscular Dystrophy

Meregalli, M., Farini, A., & Torrente, Y. (2009) · Springer eBooks · doi:10.1007/978-1-4419-1207-7_15 · Cited by 2

Current Trends in the Development of Wound Dressings, Biomaterials and Devices

Banerjee, A., & Bhattacharyya, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820352-1.00117-6 · Cited by 2

SP7 transcription factor ameliorates bone defect healing in low-density lipoprotein receptor-related protein 5 (LRP5)-dependent osteoporosis mice

Xi, Y., Jiang, Q., Dai, W. H., Chen, C., Wang, Y., Miao, X., Lai, K., Jiang, Z., Yang, G., & Wang, Y. (2025) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2300531 · Cited by 1

Ex Vivo Gene Therapy for Spinal Fusion

Kaito, T., Stephanie, S. C., & Choi, J. H.-K. (2011) · InTech eBooks · doi:10.5772/18764 · Cited by 1

DNA delivery for regeneration

Seidlits, S. K., Hlavaty, K. A., & Shea, L. D. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9780511997839.029 · Cited by 1

Bioactive Inorganic and Organic Composite Materials for Bone Regeneration and Gene Delivery

Zhang, Y., & Wu, C. (2013) · CRC Press eBooks · doi:10.1201/b13926-8 · Cited by 1

Experimental therapeutic angiogenesis after myocardial infarction : Efficacy of different angiogenic factors and delivery methods

Hao, X. (2006) · Figshare · Cited by 1

The Blood – Brain Barrier and its Effect on Absorption and Distribution

de Boer, A. G., & Gaillard, P. J. (2010) · Wiley eBooks · doi:10.1002/9780470571224.pse041 · Cited by 1

Thérapie génique du déficit immunitaire combiné sévère lié à LX

Fischer, A. (1997) · Hematology and Cell Therapy · doi:10.1007/s00282-997-0097-1 · Cited by 1

Surface Recognition and Complexations Between Synthetic Poly(ribo)nucleotides and Neutral Phospholipids and Their Implications in Lipofection

Süleymanoğlu, E. (2006) · Iranian journal of pharmaceutical research · doi:10.22037/ijpr.2010.648 · Cited by 1

Engineering Viruses for CNS studies

Lansford, R. D. (2009) · Elsevier eBooks · doi:10.1016/b978-008045046-9.02006-4 · Cited by 1

New Technologies in Cardiovascular Research: Gene Therapy

Hedman, M., Turunen, M. P., & Ylä‐Herttuala, S. (2006) · Springer eBooks · doi:10.1007/0-387-23329-6_5 · Cited by 1

Chromosomal integration in vitro and in vivo of high capacity adenoviral vectors

Stephen, S. L. (2007) · Kölner Universitäts PublikationsServer (Universität zu Köln)

Cell-Delivered Gene Therapy for HIV

Ledger, S., Savkovic, B., Millington, M., Impey, H. L., Boyd, M. P., John, M., & Symonds, G. P. (2011) · InTech eBooks · doi:10.5772/22658

IMMOBILIZED COBALT AFFINITY PURIFICATION FOR HSV-1 BASED GENE THERAPY VECTORS

Jiang, C. (2006) · D-Scholarship@Pitt (University of Pittsburgh)

Progress toward a combined bacterial and viral gene delivery system for mammalian cells

Simper, M. (2004) · Texas ScholarWorks (Texas Digital Library)

Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas

Smith, T. L. (2013) · Digital Commons-TMC (Texas Medical Center)

Efficient gene transfer mediated by HIV-1-based defective lentivector and inhibition of HIV-1 replication

Zeng, L., Ye, L., & Lu, Y. (2007) · Virologica Sinica · doi:10.1007/s12250-007-0002-7

Biotechnological Applications of Artificial Microtissues

Sánchez-Bustamante, C. D. (2009) · TDX (Tesis Doctorals en Xarxa)

Vascular Endothelial Growth Factors B and C: Gene Regulation and Gene Transfer In Vivo

Enholm, B. (2004) · Työväentutkimus Vuosikirja

« Thérapie génique du déficit immunitaire combiné sévère lié à l'X : efficacité et complications / Gene therapy of children with X-linked severe combined immune deficiency : efficiency and complications »

Fischer, A., & Cavazzana, M. (2015)

Controlling Nonviral Gene Delivery through the Cell-Biomaterial Interface

Duensing, B. A. (2010) · Lincoln (University of Nebraska)

Structure and Assembly of Membrane-Containing dsDNA Bacteriophages

Huiskonen, J. T. (2005) · Työväentutkimus Vuosikirja

Current Concepts in Gene Therapy of the Musculoskeletal System Současné názory na genovou terapii pohybového systému

Ivković, A., Pascher, A., Hudetz, D., Jelić, M., Hašpl, M., Windhager, R. H., & Pecina, M. M. (2006)

HTx-Überlebenszeitverlängerung durch Langzeitexpression löslicher Spender-MHC Klasse I-Antigene und viralem IL-10 in der Leber durch AAV-Plasmid-vermittelten Gentransfer im Rattenmodell

Doenecke, A., Frank, E., Scherer, M. N., Schlitt, H. J., & Geissler, E. K. (2008) · Langenbecks Archiv für Chirurgie. Supplement · doi:10.1007/978-3-540-78833-1_73

HIV-derived lentiviral vectors engineered for regulated transgene expression

Guarino, B. M. (2005) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-a-005063290

Manipulation of host protein expression in primary human cells: a study on HIV infection and replication.

Iannucci, V. (2013) · Ghent University Academic Bibliography (Ghent University)

Linear and Branched Chitosan Oligomers as Delivery Systems for pDNA and siRNA In Vitro and In Vivo

Issa, M. (2006) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Gene Therapy Applications for Parkinson’s Disease

Torres, E. M., Monville, C., & Dunnett, S. B. (2006) · CRC Press eBooks · doi:10.3109/9781420016390-10

Bacteriophage-Targeted Nanomedicine and Molecular Imaging

Wang, T., & Narayanaswamy, R. (2014) · Frontiers in nanobiomedical research · doi:10.1142/9789814520652_0060

Retrovirus-mediated gene therapy for Farber disease.

Ramsubir, S. (2008) · TSpace (University of Toronto)

ŠTARGARDTO GELTONOSIOS DĖMĖS DISTROFIJOS SKIRTINGOS FENOTIPINĖS IŠRAIŠKOS

Liutkevičienė, R., Glebauskienė, B., Ašmonienė, V., Gelžinis, A., Kriaučiūnienė, L., Vaičiulienė, R., Trumpaitis, J., & Žemaitienė, R. (2016) · Medicinos teorija ir praktika · doi:10.15591/mtp.2016.007

HTx-Überlebenszeitverlängerung durch Langzeitexpression löslicher Spender-MHC Klasse I-Antigene und viralem IL-10 in der Leber durch AAV-Plasmid-vermittelten Gentransfer im Rattenmodell Prolongation of heart-allograft survival after long-term expression of soluble-MHC class I-antigens and viral IL-10 in the liver by AAV-plasmid mediated gene transfer in the rat model

Doenecke, A., Frank, E., Scherer, M. N., & Geissler, E. K. (2008)

Cellular Therapies for Wiskott-Aldrich Syndrome

Braun, C. J., & Klein, C. (2016) · Springer eBooks · doi:10.1007/978-3-319-39562-3_18

Development Of Molecular And Cellular Imaging Tools To Evaluate Gene And Cell Based Therapeutic Strategies In Vivo

Xia, J. (2011) · Journal of International Crisis and Risk Communication Research

Efficient Template-Based Nanomanufacturing of Carbon Nanotube Arrays for Cell Applications

Ahmed, A. (2017) · RIT Scholar Works (Rochester Institute of Technology)

Gene Therapy and Free Flaps for Therapeutic Reconstructive Surgery

Davis, C. R., Than, P. A., & Gurtner, G. C. (2018) · Springer eBooks · doi:10.1007/978-3-319-78957-6_7

Double UP: efficient in utero electroporation via internal controlsPreprint

Taylor, R. J., Carrington, J., Taylor, K. L., Richters, K. E., Gerlach, L. R., & Dent, E. W. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/571323

Humanized Chimeric Receptors in the Therapy of Multiple Sclerosis

Moisini, I. (2007) · doi:10.21007/etd.cghs.2007.0215

An improved lentivirus vector for safer transgene integration and protein transduction

Schenkwein, D. (2013) · UEF eRepo (University of Eastern Finland)

TREATMENT POSSIBILITIES FOR ACQUIRED AND HEREDITARY DISEASES BY GENE THERAPY: A REVIEW

KUMARI, P. V. K., & EKSHITHA, V. H. G. (2021) · International Journal of Applied Pharmaceutics · doi:10.22159/ijap.2021v13i2.39995

Lentiviral Vector Mediated Gene Transfer as an Antiviral and Antitumoral Intervention Strategy

Raina, S. (2015) · Shodhganga

Adventitial ex vivo gene transfer with autologous vascular smooth muscle cells: a superior approach for delivery of therapeutics into the arterial wall?

Min, W. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2003.12.003

Gene Therapy

Khan, M. M. (2016) · Springer eBooks · doi:10.1007/978-3-319-30273-7_11

Gene Therapy

Khan, M. M. (2008) · Springer eBooks · doi:10.1007/978-0-387-77976-8_10

Clinical Protocol: Phase I Study of an Adenovirus/Prostate-Specific Antigen Vaccine in Men with Metastatic Prostate Cancer

Lubaroff, D. M., Konety, B. R., Link, B. K., Link, T. L., Madsen, T., Shannon, M., Ecklund, D. J., & Williams, R. D. (2006) · Human Gene Therapy · doi:10.1089/hum.2006.17.ft-168

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Smirnova, M. P., Osipova, A. A., Borodinova, A. A., Bagrinovtseva, T. M., Dobryakova, Y. V., Смирнов, И. В., & Malyshev, A. Y. (2025) · Journal of Visualized Experiments · doi:10.3791/68235

Polymeric Delivery of DNA‐Encoded Biologics

Ting, J., Dykeman-Bermingham, P. A., Cairns, C. E., Petersen, S. R., Snell, N. J., Miskin, R. P., Fisher, J. D., Murthy, S. K., Kevlahan, S., Guzman, G., et al. (2026) · Macromolecular Chemistry and Physics · doi:10.1002/macp.202500421

Stargardt's Macular Dystrophy different phenotipical aspects

Liutkevičienė, R., Glebauskienė, B., Ašmonienė, V., Gelžinis, A., Kriaučiūnienė, L., Vaičiulienė, R., Trumpaitis, J., & Žemaitienė, R. (2015) · Lithuanian University of Health Sciences

Lentivirus and shRNA models for the delivery and regulation of bone sialoprotein functional domains

Johar, D., & Abdulrahman, M. S. (2026) · Next research. · doi:10.1016/j.nexres.2026.102037

Viral vectors in drug delivery: Design and applications

Chouhan, N. K., Sharma, M., Rawat, M., Talati, M. N., Kaur, H., Sharma, A., & Vinchurkar, K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40620-1.00009-1

Design of artificial microtissues

Kelm, J. M. (2005) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-a-005064702

First published online as a Review in Advance on March 11, 2005 GENE THERAPY: Twenty-First Century Medicine

Verma, I. M., & Weitzman, M. D. (2005)

GENE THERAPY: Twenty-First Century Medicine

Verma, I. M., & Weitzman, M. D. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.050304.091637 · Cited by 630

A Review on Gene Therapy

Pravalika, G., Maheshwari, K., Divya, B., Shirisha, G., & Balakoti, J. (2024) · International Journal of Pharmaceutical and Biological Science Archive

Gene Therapy: The Molecular Bandage for Treating Genetic Disorders

Karim, M. M. (1970) · Anwer Khan Modern Medical College Journal · doi:10.3329/akmmcj.v3i1.10110

Viral mediated gene therapy

Murphy, B. J. (1999) · Springer eBooks · doi:10.1007/978-94-017-0926-2_19 · Cited by 2