The DOI matches its Crossref record; 224 of the 224 references it cites were found in a registry or an index.
THE REGULATION AND PHARMACOLOGY OF ENDOTHELIAL NITRIC OXIDE SYNTHASE
Abstract
▪ Abstract Nitric oxide (NO) is a small, diffusible, lipophilic free radical gas that mediates significant and diverse signaling functions in nearly every organ system in the body. The endothelial isoform of nitric oxide synthase (eNOS) is a key source of NO found in the cardiovascular system. This review summarizes the pharmacology of NO and the cellular regulation of endothelial NOS (eNOS). The molecular intricacies of the chemistry of NO and the enzymology of NOSs are discussed, followed by a review of the biological activities of NO. This information is then used to develop a more global picture of the pharmacological control of NO synthesis by NOSs in both physiologic conditions and pathophysiologic states.
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Metadata
- Authors
- Dudzinski, D. M., Igarashi, J., Greif, D., & Michel, T.
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 2006-02-01
- Volume
- 46
- Issue
- 1
- Pages
- 235-276
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- OpenAlex
- W2118272405
- Cited by
- 425
- References
- 224
- FWCI
- 3.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: THE REGULATION AND PHARMACOLOGY OF ENDOTHELIAL NITRIC OXIDE SYNTHASE. https://app.cochat.ai/papers/10.1146/annurev.pharmtox.44.101802.121844
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- Dudzinski, D. M., Igarashi, J., Greif, D., & Michel, T. (2006). THE REGULATION AND PHARMACOLOGY OF ENDOTHELIAL NITRIC OXIDE SYNTHASE. Annual Review of Pharmacology and Toxicology. https://doi.org/10.1146/annurev.pharmtox.44.101802.121844
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
