The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
CALCIUM-ACTIVATED CHLORIDE CHANNELS
Abstract
▪ Abstract Calcium-activated chloride channels (CaCCs) play important roles in cellular physiology, including epithelial secretion of electrolytes and water, sensory transduction, regulation of neuronal and cardiac excitability, and regulation of vascular tone. This review discusses the physiological roles of these channels, their mechanisms of regulation and activation, and the mechanisms of anion selectivity and conduction. Despite the fact that CaCCs are so broadly expressed in cells and play such important functions, understanding these channels has been limited by the absence of specific blockers and the fact that the molecular identities of CaCCs remains in question. Recent status of the pharmacology and molecular identification of CaCCs is evaluated.
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Citations
Cites
Amino acid pharmacology of mammalian central neurones grown in tissue culture
Barker, J. L., & Ransom, B. R. (1978) · The Journal of Physiology · doi:10.1113/jphysiol.1978.sp012387 · Cited by 265
Cited by
Namkung, W., Phuan, P.-W., & Verkman, A. S. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.175109 · Cited by 353
Cryo-EM structures of the TMEM16A calcium-activated chloride channel
Dang, S., Feng, S., Tien, J., Peters, C. J., Bulkley, D., Lolicato, M., Zhao, J., Zuberbühler, K., Ye, W., Qi, L., et al. (2017) · Nature · doi:10.1038/nature25024 · Cited by 333
Studies on expression and function of the TMEM16A calcium-activated chloride channel
Huang, F., Rock, J. R., Harfe, B. D., Cheng, T., Huang, X., Jan, Y. N., & Jan, L. Y. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911935106 · Cited by 310
Davis, M. J., Earley, S., Li, Y.-S., & Chien, S. (2023) · Physiological Reviews · doi:10.1152/physrev.00053.2021 · Cited by 273
WIMMERS, S., KARL, M., & STRAUSS, O. (2007) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2006.12.002 · Cited by 207
Metadata
- Authors
- Hartzell, C., Putzier, I., & Arreola, J.
- Venue
- Annual Review of Physiology
- Publisher
- Annual Reviews
- Published
- 2005-03-17
- Volume
- 67
- Issue
- 1
- Pages
- 719-758
- ISSN
- 0066-4278 (ISSN-L)
- 1545-1585
- OpenAlex
- W2112543188
- Cited by
- 626
- References
- 1
- FWCI
- 1.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hartzell, C., Putzier, I., & Arreola, J. (2005). CALCIUM-ACTIVATED CHLORIDE CHANNELS. Annual Review of Physiology. https://doi.org/10.1146/annurev.physiol.67.032003.154341
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.