Cited by 284Sperm and Testicular FunctionReproductive biology and impacts on aquatic speciesReproductive Biology and Fertility

Mechanisms of sperm chemotaxis

Kaupp, U. Benjamin, Kashikar, Nachiket D., Weyand, Ingo·2008·Annual Review of Physiology

Abstract

Sperm are attracted by chemical factors that are released by the egg-a process called chemotaxis. Most of our knowledge on sperm chemotaxis originates from the study of marine invertebrates. In recent years, the main features of the chemotactic signaling pathway and the swimming behavior evoked by chemoattractants have been elucidated in sea urchins. In contrast, our understanding of mammalian sperm chemotaxis is still rudimentary and subject to an ongoing debate. In this review, we raise new questions and discuss current concepts of sperm chemotaxis. Finally, we highlight commonalities and differences of sensory signaling in sperm, photoreceptors, and olfactory neurons.

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Crossref · 10.1146/annurev.physiol.70.113006.100654

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146 of 146 references verified0 citation errors · 0 not checkable

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  • Various single-celled eukaryotes (protists) and ciliated larvae of sponges devoid of neurons can display sophisticated behaviours, including phototaxis, gravitaxis or chemotaxis.

    “Various single-celled eukaryotes (protists) and the ciliated larvae of sponges devoid of neurons can display sophisticated behaviours, including phototaxis, gravitaxis or chemotaxis.”

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Authors
Kaupp, U. B., Kashikar, N. D., & Weyand, I.
Affiliations
Forschungszentrum Jülich (DE)
Venue
Annual Review of Physiology
Published
2008-03-01
Volume
70
Issue
1
Pages
93-117
ISSN
  • 0066-4278 (ISSN-L)
  • 1545-1585
OpenAlex
W2155214806
Cited by
284
References
144
Citations by year
2026: 4 · 2025: 8 · 2024: 12 · 2023: 7 · 2022: 11 · 2021: 18 · 2020: 18 · 2019: 14 · 2018: 8 · 2017: 19 · 2016: 10 · 2015: 19 · 2014: 23 · 2013: 23 · 2012: 14
FWCI
2.15
Type
journal article
Language
en
Open access
closed
Locations
  • Annual Review of Physiology (publishedVersion)
  • PubMed (publishedVersion)
  • JuSER (Forschungszentrum Jülich) (submittedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Keywords
sperm chemotaxis, chemotactic signaling, chemoattractants, sea urchin sperm, mammalian sperm, sensory signaling, photoreceptors, olfactory sensory neurons
MeSH terms
Animals, Chemotaxis, Humans, Male, Sperm Motility, Spermatozoa, Signal Transduction

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