The DOI matches its Crossref record; 244 of the 245 references it cites were found in a registry or an index.
Salicylic Acid, a Multifaceted Hormone to Combat Disease
Abstract
For more than 200 years, the plant hormone salicylic acid (SA) has been studied for its medicinal use in humans. However, its extensive signaling role in plants, particularly in defense against pathogens, has only become evident during the past 20 years. This review surveys how SA in plants regulates both local disease resistance mechanisms, including host cell death and defense gene expression, and systemic acquired resistance (SAR). Genetic studies reveal an increasingly complex network of proteins required for SA-mediated defense signaling, and this process is amplified by several regulatory feedback loops. The interaction between the SA signaling pathway and those regulated by other plant hormones and/or defense signals is also discussed.
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“SAR represents a systemic induced immune response of plants, contributing to a durable and broad spectrum resistance to a vast majority of harmful microbes, such as bacteria, fungi, or viruses (Vlot et al., 2009).”
From Intensify production, transform biomass to energy and novel goods and protect soils in Europe—A vision how to mobilize marginal lands (2018) · cites this paper as Vlot et al., 2009
Citations
Cites
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Contrasting Mechanisms of Defense Against Biotrophic and Necrotrophic Pathogens
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Foyer, C. H., & Noctor, G. (2005) · The Plant Cell · doi:10.1105/tpc.105.033589 · Cited by 2,961
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
Chisholm, S. T., Coaker, G., Day, B., & Staskawicz, B. J. (2006) · Cell · doi:10.1016/j.cell.2006.02.008 · Cited by 2,957
Isochorismate synthase is required to synthesize salicylic acid for plant defence
Wildermuth, M. C., Dewdney, J., Wu, G., & Ausubel, F. M. (2001) · Nature · doi:10.1038/35107108 · Cited by 2,333
A Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling
Navarro, L., Dunoyer, P., Jay, F., Arnold, B., Dharmasiri, N., Estelle, M. A., Voinnet, O., & Jones, J. D. G. (2006) · Science · doi:10.1126/science.1126088 · Cited by 2,004
Requirement of Salicylic Acid for the Induction of Systemic Acquired Resistance
Gaffney, T. D., Friedrich, L., Vernooij, B., Negrotto, D. V., Nye, G., Uknes, S. J., Ward, E. R., Keßmann, H., & Ryals, J. A. (1993) · Science · doi:10.1126/science.261.5122.754 · Cited by 1,855
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A Central Role of Salicylic Acid in Plant Disease Resistance
Delaney, T. P., Uknes, S. J., Vernooij, B., Friedrich, L., Weymann, K. B., Negrotto, D. V., Gaffney, T. D., Gut-Rella, M., Keßmann, H., Ward, E. R., et al. (1994) · Science · doi:10.1126/science.266.5188.1247 · Cited by 1,754
Research works printed but not linked: 1
- 10.1104/pp.010096 · DOI
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Sorted by citations
Induced systemic resistance by beneficial microbes
Pieterse, C. M. J., Zamioudis, C., Berendsen, R. L., Weller, D. M., Van Wees, S. C. M., & Bakker, P. A. H. M. (2014) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-082712-102340 · Cited by 3,272
Hormonal Modulation of Plant Immunity
Pieterse, C. M. J., van der Does, D., Zamioudis, C., León-Reyes, A., & Wees, S. C. M. V. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154055 · Cited by 3,128
Wasternack, C., & Hause, B. (2013) · Annals of Botany · doi:10.1093/aob/mct067 · Cited by 2,629
Mittler, R., Vanderauwera, S., Suzuki, N., Miller, G., Tognetti, V. B., Vandepoele, K., Gollery, M., Shulaev, V., & Breusegem, F. V. (2011) · Trends in Plant Science · doi:10.1016/j.tplants.2011.03.007 · Cited by 2,324
Growth–Defense Tradeoffs in Plants: A Balancing Act to Optimize Fitness
Huot, B., Yao, J., Montgomery, B. L., & He, S. Y. (2014) · Molecular Plant · doi:10.1093/mp/ssu049 · Cited by 1,916
Metadata
- Authors
- Vlot, A. C., Dempsey, D. A., & Klessig, D. F.
- Affiliations
- Helmholtz Munich (DE)
- Boyce Thompson Institute (US)
- Venue
- Annual Review of Phytopathology
- Publisher
- Annual Reviews
- Published
- 2009-09-01
- Volume
- 47
- Issue
- 1
- Pages
- 177-206
- ISSN
- 0066-4286 (ISSN-L)
- 1545-2107
- OpenAlex
- W2143014195
- Cited by
- 2,568
- References
- 245
- Citations by year
- 2026: 130 · 2025: 145 · 2024: 140 · 2023: 172 · 2022: 218 · 2021: 210 · 2020: 227 · 2019: 167 · 2018: 159 · 2017: 142 · 2016: 134 · 2015: 150 · 2014: 158 · 2013: 150 · 2012: 119
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Phytopathology (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- Site cant be reached (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- National Science Foundation
- Institute of Materials Research and Engineering
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Pathogenic Bacteria Studies
- Keywords
- salicylic acid, plant disease resistance, systemic acquired resistance, plant defense signaling, host cell death, defense gene expression, plant hormones, feedback loops, plant-pathogen interaction
- MeSH terms
- Plant Diseases, Plant Growth Regulators, Plant Proteins, Plants, Signal Transduction, Salicylic Acid
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