The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Head and Neck Lesions: Characterization with Diffusion-weighted Echo-planar MR Imaging
Abstract
PURPOSE: To evaluate whether apparent diffusion coefficients (ADCs) calculated from diffusion-weighted echo-planar magnetic resonance (MR) images can be used to characterize head and neck lesions. MATERIALS AND METHODS: Diffusion-weighted echo-planar MR imaging was performed with a 1.5-T MR unit in 97 head and neck lesions in 97 patients. Images were obtained with a diffusion-weighted factor, factor b, of 0, 500, and 1,000 sec/mm(2), and an ADC map was constructed. The ADCs of lesions, cerebrospinal fluid, and spinal cord were calculated. RESULTS: Acceptable images for ADC measurement were obtained in 81 (84%) patients. The mean ADC of malignant lymphomas, (0.66 +/- 0.17[SD]) x 10(-3) mm(2)/sec (n = 13), was significantly smaller (P <.001) than that of carcinomas. The mean ADC of carcinomas, (1.13 +/- 0.43) x 10(-3) mm(2)/sec (n = 36), was significantly smaller (P =.002) than that of benign solid tumors. The mean ADC of benign solid tumors, (1.56 +/- 0.51) x 10(-3) mm(2)/sec (n = 22), was significantly smaller (P =.035) than that of benign cystic lesions, (2.05 +/- 0.62) x 10(-3) mm(2)/sec (n = 10). No significant differences were seen in the mean ADC of cerebrospinal fluid and of spinal cord among four groups of lesions. When an ADC smaller than 1.22 x 10(-3) mm(2)/sec was used for predicting malignancy, the highest accuracy of 86%, with 84% sensitivity and 91% specificity, was obtained. CONCLUSION: Measurement of ADCs may be used to characterize head and neck lesions.
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Cited by
Hamstra, D. A., Chenevert, T. L., Moffat, B. A., Johnson, T. D., Meyer, C. R., Mukherji, S. K., Quint, D. J., Gebarski, S. S., Fan, X., Tsien, C. I., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508347102 · Cited by 287
Nakayama, T., Yoshimitsu, K., Irie, H., Aibe, H., Tajima, T., Nishie, A., Asayama, Y., Matake, K., Kakihara, D., Matsuura, S., et al. (2005) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20369 · Cited by 168
Metadata
- Authors
- Wang, J., Takashima, S., Takayama, F., Kawakami, S., Saito, A., Matsushita, T., Momose, M., & Ishiyama, T.
- Venue
- Radiology
- Published
- 2001-09
- Volume
- 220
- Issue
- 3
- Pages
- 621-630
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2035359738
- Cited by
- 566
- References
- 22
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wang, J., Takashima, S., Takayama, F., Kawakami, S., Saito, A., Matsushita, T., Momose, M., & Ishiyama, T. (2001). Head and Neck Lesions: Characterization with Diffusion-weighted Echo-planar MR Imaging. Radiology. https://doi.org/10.1148/radiol.2202010063
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