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Adrenal Masses: Characterization with Combined Unenhanced and Delayed Enhanced CT

Caoili, Elaine M., Korobkin, Melvyn, Francis, Isaac R., Cohan, Richard H., Platt, Joel F., Dunnick, N. Reed, Raghupathi, Kartik I.·2002·Radiology

Abstract

PURPOSE: To assess the accuracy of a dedicated adrenal computed tomographic (CT) protocol. MATERIALS AND METHODS: One hundred sixty-six adrenal masses were evaluated with a protocol consisting of unenhanced CT, and, for those with attenuation values greater than 10 HU, contrast material-enhanced and delayed enhanced CT. Attenuation values and enhancement washout calculations were obtained. An adenoma was diagnosed if a mass had an attenuation value of 10 HU or less at unenhanced CT or a percentage enhancement washout value of 60% or higher. RESULTS: The final diagnosis was adenoma in 127 masses and non-adenoma in 39. Masses measuring more than 10 HU on unenhanced CT scans were confirmed at biopsy (n = 28) or were examined for stability or change in size at follow-up CT performed at a minimum interval of 6 months (n = 33). Thirty-six (92%) of 39 non-adenomas and 124 (98%) of 127 adenomas were correctly characterized. The sensitivity and specificity of this protocol were 98% and 92%, respectively. This protocol correctly characterized 160 (96%) of 166 masses. CONCLUSION: With a combination of unenhanced and delayed enhanced CT, nearly all adrenal masses can be correctly categorized as adenomas or non-adenomas.

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Metadata

Authors
Caoili, E. M., Korobkin, M., Francis, I. R., Cohan, R. H., Platt, J. F., Dunnick, N. R., & Raghupathi, K. I.
Venue
Radiology
Published
2002-03
Volume
222
Issue
3
Pages
629-633
ISSN
  • 0033-8419 (ISSN-L)
  • 1527-1315
OpenAlex
W2018257960
Cited by
690
References
2
FWCI
14.52
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Adrenal Masses: Characterization with Combined Unenhanced and Delayed Enhanced CT. https://app.cochat.ai/papers/10.1148/radiol.2223010766
The paper
Caoili, E. M., Korobkin, M., Francis, I. R., Cohan, R. H., Platt, J. F., Dunnick, N. R., & Raghupathi, K. I. (2002). Adrenal Masses: Characterization with Combined Unenhanced and Delayed Enhanced CT. Radiology. https://doi.org/10.1148/radiol.2223010766

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