Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline

Lenders, Jacques W. M.; Duh, Quan-Yang; Eisenhofer, Graeme; Gimenez-Roqueplo, Anne-Paule; Grebe, Stefan K. G.; Murad, Mohammad Hassan; Naruse, Mitsuhide; Pacak, Karel; Young, William F.

doi:10.1210/jc.2014-1498

Cited by 2,827Adrenal and Paraganglionic TumorsNeuroendocrine Tumor Research AdvancesRenal cell carcinoma treatment

Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline

Open access

Lenders, Jacques W. M., Duh, Quan-Yang, Eisenhofer, Graeme, Gimenez-Roqueplo, Anne-Paule, Grebe, Stefan K. G., Murad, Mohammad Hassan, Naruse, Mitsuhide, Pacak, Karel +1 more·2014·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2014-1498

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: The aim was to formulate clinical practice guidelines for pheochromocytoma and paraganglioma (PPGL). PARTICIPANTS: The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), seven experts in the field, and a methodologist. The authors received no corporate funding or remuneration. EVIDENCE: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews. CONSENSUS PROCESS: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society, European Society of Endocrinology, and Americal Association for Clinical Chemistry reviewed drafts of the guidelines. CONCLUSIONS: The Task Force recommends that initial biochemical testing for PPGLs should include measurements of plasma free or urinary fractionated metanephrines. Consideration should be given to preanalytical factors leading to false-positive or false-negative results. All positive results require follow-up. Computed tomography is suggested for initial imaging, but magnetic resonance is a better option in patients with metastatic disease or when radiation exposure must be limited. (123)I-metaiodobenzylguanidine scintigraphy is a useful imaging modality for metastatic PPGLs. We recommend consideration of genetic testing in all patients, with testing by accredited laboratories. Patients with paraganglioma should be tested for SDHx mutations, and those with metastatic disease for SDHB mutations. All patients with functional PPGLs should undergo preoperative blockade to prevent perioperative complications. Preparation should include a high-sodium diet and fluid intake to prevent postoperative hypotension. We recommend minimally invasive adrenalectomy for most pheochromocytomas with open resection for most paragangliomas. Partial adrenalectomy is an option for selected patients. Lifelong follow-up is suggested to detect recurrent or metastatic disease. We suggest personalized management with evaluation and treatment by multidisciplinary teams with appropriate expertise to ensure favorable outcomes.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1210/jc.2014-1498

Cites

267 of 267 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

SDHB (10.3%) and SDHD (8.9%) mutations are the most frequent germline mutations in pheochromocytoma and paragangliomas.
“SDHB (10.3%) and SDHD (8.9%) mutations are the most frequent germline mutations in pheochromocytoma and paragangliomas (180).”
From Adrenal incidentaloma (2020) · cites this paper as [180]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Part of this paper’s reference list could not be split into single entries.

Grading quality of evidence and strength of recommendations
(2004) · BMJ · doi:10.1136/bmj.328.7454.1490 · Cited by 8,477 · see citing works
Williams Textbook of Endocrinology
Melmed, S., & Polonsky, K. С. (2016) · Elsevier eBooks · doi:10.1016/c2013-0-15980-6 · Cited by 3,716 · see citing works
Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene
Latif, F., Tory, K., Gnarra, J. R., Yao, M., Duh, F.-M. C., Orcutt, M. L., Stackhouse, T. M., Kuzmin, I., Modi, W. S., Geil, L., et al. (1993) · Science · doi:10.1126/science.8493574 · Cited by 2,971 · see citing works
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
Mulligan, L. M., Kwok, J. B., Healey, C. S., Elsdon, M. J., Eng, C., Gardner, E., Love, D. R., Mole, S., Moore, J. K., Papi, L., et al. (1993) · Nature · doi:10.1038/363458a0 · Cited by 1,956 · see citing works
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
Baysal, B. E., Ferrell, R. E., Willett-Brozick, J. E., Lawrence, E. C., Myssiorek, D., Bosch, A., Mey, A. V. D., Taschner, P. E. M., Rubinstein, W. S., Myers, E. N., et al. (2000) · Science · doi:10.1126/science.287.5454.848 · Cited by 1,638 · see citing works
Phaeochromocytoma
Lenders, J. W. M., Eisenhofer, G., Mannelli, M., & Pacák, K. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67139-5 · Cited by 1,541 · see citing works
Self-citation
Germ-Line Mutations in Nonsyndromic Pheochromocytoma
Neumann, H. P. H., Bausch, B., McWhinney, S. R., Bender, B., Gimm, O., Franke, G., Schipper, J., Klisch, J., Altehoefer, C., Zerres, K., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020152 · Cited by 1,350 · see citing works
Biochemical Diagnosis of Pheochromocytoma: Which Test Is Best?
Lenders, J. W. M., Pacak, K., Walther, M. M., Linehan, W. M., Mannelli, M., Friberg, P., Keiser, H. R., Goldstein, D. S., & Eisenhofer, G. (2002) · JAMA · doi:10.1001/jama.287.11.1427 · Cited by 1,134 · see citing works
Self-citation
Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
Astuti, D., Latif, F., Dallol, A., Dahia, P. L. M., Douglas, F., George, E., Sköldberg, F., Husebye, E. S., Eng, C., & Maher, E. R. (2001) · The American Journal of Human Genetics · doi:10.1086/321282 · Cited by 1,087 · see citing works
Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus
Viskochil, D. H., Buchberg, A. M., Xu, G., Cawthon, R., Stevens, J., Wolff, R. K., Culver, M., Carey, J. C., Copeland, N. G., Jenkins, N. A., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90252-a · Cited by 1,082 · see citing works
Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine
Eisenhofer, G., Kopin, I. J., & Goldstein, D. S. (2004) · Pharmacological Reviews · doi:10.1124/pr.56.3.1 · Cited by 1,072 · see citing works
Self-citation
Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results
Plon, S. E., Eccles, D. M., Easton, D., Foulkes, W. D., Genuardi, M., Greenblatt, M. S., Hogervorst, F. B. L., Hoogerbrugge, N., Spurdle, A. B., Tavtigian, S. V., et al. (2008) · Human Mutation · doi:10.1002/humu.20880 · Cited by 912 · see citing works
A Survey on Adrenal Incidentaloma in Italy
Mantero, F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.2.637 · Cited by 907 · see citing works
Distinct Clinical Features of Paraganglioma Syndromes Associated With <EMPH TYPE="ITAL">SDHB</EMPH> and <EMPH TYPE="ITAL">SDHD</EMPH> Gene Mutations
Neumann, H. P. H. (2004) · JAMA · doi:10.1001/jama.292.8.943 · Cited by 893 · see citing works
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
Niemann, S., & Müller, U. (2000) · Nature Genetics · doi:10.1038/81551 · Cited by 875 · see citing works
ACMG recommendations for standards for interpretation and reporting of sequence variations: Revisions 2007
Richards, C. S., Bale, S., Bellissimo, D. B., Das, S., Grody, W. W., Hegde, M. R., Lyon, E., & Ward, B. E. (2008) · Genetics in Medicine · doi:10.1097/gim.0b013e31816b5cae · Cited by 832 · see citing works
The clinically inapparent adrenal mass: update in diagnosis and management
Mansmann, G., Lau, J., Balk, E., Rothberg, M., Miyachi, Y., & Bornstein, S. R. (2004) · Endocrine Reviews · doi:10.1210/er.2002-0031 · Cited by 781 · see citing works
American Society of Clinical Oncology Policy Statement Update: Genetic Testing for Cancer Susceptibility
(2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.03.189 · Cited by 748 · see citing works
Williams Textbook of Endocrinology
Reutrakul, S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000323673.44568.e8 · Cited by 710 · see citing works
SDH5 , a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
Hao, H.-X., Khalimonchuk, O., Schraders, M., Dephoure, N., Bayley, J.-P., Kunst, H., Devilee, P., Cremers, C. W. R. J., Schiffman, J. D., Bentz, B. G., et al. (2009) · Science · doi:10.1126/science.1175689 · Cited by 702 · see citing works
Adrenal Masses: Characterization with Combined Unenhanced and Delayed Enhanced CT
Caoili, E. M., KOROBKIN, M. T., Francis, I. R., Cohan, R. H., Platt, J. F., Dunnick, N. R., & Raghupathi, K. I. (2002) · Radiology · doi:10.1148/radiol.2223010766 · Cited by 684 · see citing works
Genetic Testing in Pheochromocytoma or Functional Paraganglioma
Amar, L., Bertherat, J. Y., Baudin, É., Ajzenberg, C., Paillerets, B. B., Chabre, O., Chamontin, B., Delemer, B., Giraud, S., Murat, A., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.1484 · Cited by 683 · see citing works
Self-citation
SDHA is a tumor suppressor gene causing paraganglioma
Burnichon, N., Brière, J.-J., Libé, R., Vescovo, L., Rivière, J., Tissier, F., Jouanno, E., Jeunemaı̂tre, X., Bénit, P., Tzagoloff, A., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq206 · Cited by 645 · see citing works
Self-citation
Preoperative Management of the Pheochromocytoma Patient
Pacák, K. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1720 · Cited by 569 · see citing works
Clinical Presentation and Penetrance of Pheochromocytoma/Paraganglioma Syndromes
Benn, D. E., Gimenez‐Roqueplo, A., Reilly, J. R., Bertherat, J. Y., Burgess, J. R., Byth, K., CROXSON, M. S., Dahia, P. L. M., Elston, M. S., Gimm, O., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1862 · Cited by 565 · see citing works
Self-citation
Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan.
OMURA, M., SAITO, J., YAMAGUCHI, K., KAKUTA, Y., & NISHIKAWA, T. (2004) · Hypertension Research · doi:10.1291/hypres.27.193 · Cited by 562 · see citing works
Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas.
Gimenez‐Roqueplo, A., Favier, J., Rustin, P., Rieubland, C., Crespin, M., Nau, V., Kien, P. K. V., Corvol, P. L., Plouin, P., & Jeunemaı̂tre, X. (2003) · PubMed · Cited by 541 · see citing works
Self-citation
An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis
van Nederveen, F. H., Gaal, J., Favier, J., Korpershoek, E., Oldenburg, R. A., de Bruyn, E. M., Sleddens, H. F. B. M., Derkx, P., Rivière, J., Dannenberg, H., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70164-0 · Cited by 534 · see citing works
Self-citation
Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma
Comino‐Méndez, I., Gracia-Aznárez, F. J., Schiavi, F., Landa, I., Leandro-Garcia, L. J., Letón, R., Honrado, E., Ramos‐Medina, R., Caronia, D., Pita, G., et al. (2011) · Nature Genetics · doi:10.1038/ng.861 · Cited by 528 · see citing works
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer
Lee, S., Nakamura, E., Yang, H., Wei, W., Linggi, M. S., Sajan, M. P., Farese, R. V., Freeman, R. S., Carter, B. D., Kaelin, W. G., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.06.015 · Cited by 527 · see citing works
A Comparison of Biochemical Tests for Pheochromocytoma: Measurement of Fractionated Plasma Metanephrines Compared with the Combination of 24-Hour Urinary Metanephrines and Catecholamines
Sawka, A. M., Jaeschke, R., Singh, R. J., & Young, W. F. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021251 · Cited by 503 · see citing works
Self-citation
Biochemical Diagnosis of Pheochromocytoma: How to Distinguish True- from False-Positive Test Results
Eisenhofer, G., Goldstein, D. S., Walther, M. M., Friberg, P., Lenders, J. W. M., Keiser, H. R., & Pacak, K. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-030005 · Cited by 492 · see citing works
Self-citation
Clinical Experience Over 48 Years With Pheochromocytoma
Goldstein, R. E., O’Neill, J. A., Holcomb, G. W., III, Morgan, W. M., Neblett, W. W., Oates, J. A., Brown, N., Nadeau, J., Smith, B., Page, D. L., et al. (1999) · Annals of Surgery · doi:10.1097/00000658-199906000-00001 · Cited by 463 · see citing works
Succinate Dehydrogenase B Gene Mutations Predict Survival in Patients with Malignant Pheochromocytomas or Paragangliomas
Amar, L., Baudin, É., Burnichon, N., Peyrard, S., Silvera, S., Bertherat, J. Y., BERTAGNA, X. Y., Schlumberger, M. J., Jeunemaı̂tre, X., Gimenez‐Roqueplo, A., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0709 · Cited by 447 · see citing works
Self-citation
The effect of age on prevalence of secondary forms of hypertension in 4429 consecutively referred patients.
Anderson, G. H., Blakeman, N., & Streeten, D. H. P. (1994) · Journal of Hypertension · doi:10.1097/00004872-199405000-00015 · Cited by 403 · see citing works
SomaticHIF2AGain-of-Function Mutations in Paraganglioma with Polycythemia
Zhuang, Z., Yang, C., Lorenzo, F., Merino, M., Fojo, T., Kebebew, E., Popovic, V., Stratakis, C. A., Prchal, J. T., & Pacak, K. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1205119 · Cited by 397 · see citing works
Comparison of 18F-Fluoro-L-DOPA, 18F-Fluoro-Deoxyglucose, and 18F-Fluorodopamine PET and 123I-MIBG Scintigraphy in the Localization of Pheochromocytoma and Paraganglioma
Timmers, H. J. L. M., Chen, C. C., Carrasquillo, J. A., Whatley, M. A., Ling, A. L., Havekes, B., Eisenhofer, G., Martiniova, L., Adams, K. T., & Pacák, K. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1248 · Cited by 395 · see citing works
Self-citation
McARDLE'S SYNDROME
Mellick, R. S., Mahler, R., & Hughes, B. P. (1962) · The Lancet · doi:10.1016/s0140-6736(62)92145-1 · Cited by 390 · see citing works
Evolving Concepts in the Pathophysiology, Diagnosis, and Treatment of Pheochromocytoma
Bravo, E. L. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-3-356 · Cited by 385 · see citing works
Germline mutations in TMEM127 confer susceptibility to pheochromocytoma
Qin, Y., Yao, L., King, E. E., Buddavarapu, K., Lenci, R. E., Chocron, E. S., Lechleiter, J. D., Sass, M., Aronin, N., Schiavi, F., et al. (2010) · Nature Genetics · doi:10.1038/ng.533 · Cited by 379 · see citing works
Plasma methoxytyramine: A novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status
Eisenhofer, G., Lenders, J. W. M., Siegert, G., Bornstein, S. R., Friberg, P., Milosevic, D., Mannelli, M., Linehan, W. M., Adams, K. T., Timmers, H. J. L. M., et al. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.07.016 · Cited by 375 · see citing works
Self-citation
The Succinate Dehydrogenase Genetic Testing in a Large Prospective Series of Patients with Paragangliomas
Burnichon, N., Rohmer, V., Amar, L., Herman, P., Leboulleux, S., Darrouzet, V., Niccoli, P., Gaillard, D. A., Chabrier, G., Chabolle, F., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2504 · Cited by 374 · see citing works
Self-citation
Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas
Welander, J., Söderkvist, P., & Gimm, O. (2011) · Endocrine Related Cancer · doi:10.1530/erc-11-0170 · Cited by 356 · see citing works
Plasma Normetanephrine and Metanephrine for Detecting Pheochromocytoma in von Hippel–Lindau Disease and Multiple Endocrine Neoplasia Type 2
Eisenhofer, G., Lenders, J. W. M., Linehan, W. M., Walther, M. M., Goldstein, D. S., & Keiser, H. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906173402404 · Cited by 346 · see citing works
Self-citation
Germline SDHB Mutations and Familial Renal Cell Carcinoma
Ricketts, C. J., Woodward, E. R., Killick, P., Morris, M. R., Astuti, D., Latif, F., & Maher, E. R. (2008) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djn254 · Cited by 341 · see citing works
Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations inSDHBandSDHD
Ricketts, C. J., Forman, J., Rattenberry, E., Bradshaw, N., Lalloo, F. I., Izatt, L., Cole, T. R. P., Armstrong, R., Kumar, V. K. A., Morrison, P. J., et al. (2009) · Human Mutation · doi:10.1002/humu.21136 · Cited by 338 · see citing works
Superiority of Fluorodeoxyglucose Positron Emission Tomography to Other Functional Imaging Techniques in the Evaluation of Metastatic SDHB-Associated Pheochromocytoma and Paraganglioma
Timmers, H. J. L. M., Kozupa, A., Chen, C. C., Carrasquillo, J. A., Ling, A. L., Eisenhofer, G., Adams, K. T., Solis, D. C., Lenders, J. W. M., & Pacák, K. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.09.6297 · Cited by 337 · see citing works
Self-citation
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressorPreprint
Schlisio, S., Kenchappa, R. S., Vredeveld, L. C. W., George, R. E., Stewart, R. A., Greulich, H. E., Shahriari, K. S., Nguyen, N. V., Pigny, P., Dahia, P. L. M., et al. (2008) · Genes & Development · doi:10.1101/gad.1648608 · Cited by 331 · see citing works
MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma
Burnichon, N., Cascón, A., Schiavi, F., Morales, N. P., Comino‐Méndez, I., Abermil, N., Inglada‐Pérez, L., de Cubas, A. A., Amar, L., Barontini, M., et al. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-0160 · Cited by 331 · see citing works
Self-citation
Pheochromocytomas: Detection with18F DOPA Whole-Body PET—Initial Results
Hoegerle, S., Nitzsche, E. U., Altehoefer, C., et al. (2002) · Radiology · doi:10.1148/radiol.2222010622 · Cited by 326 · see citing works
PHD2 Mutation and Congenital Erythrocytosis with Paraganglioma
Ladroue, C., Carcenac, R., Leporrier, M., Gad, S., Le Hello, C., Galateau-Salle, F., Feunteun, J., Pouysségur, J., Richard, S., & Gardie, B. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806277 · Cited by 323 · see citing works
High Frequency ofSDHBGermline Mutations in Patients with Malignant Catecholamine-Producing Paragangliomas: Implications for Genetic Testing
Brouwers, F. M., Eisenhofer, G., Tao, J. J., Kant, J. A., Adams, K. T., Linehan, W. M., & Pacák, K. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0423 · Cited by 314 · see citing works
Self-citation
Pheochromocytomas in von Hippel-Lindau Syndrome and Multiple Endocrine Neoplasia Type 2 Display Distinct Biochemical and Clinical Phenotypes
Eisenhofer, G., Walther, M. M., Huynh, T., Li, S., Bornstein, S. R., Vortmeyer, A. O., Mannelli, M., Goldstein, D. S., Linehan, W. M., Lenders, J. W. M., et al. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.5.7496 · Cited by 313 · see citing works
Self-citation
The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney–Stratakis syndrome): molecular genetics and clinical implications
Stratakis, C. A., & Carney, J. A. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02110.x · Cited by 311 · see citing works
Pheochromocytomas: Imaging with 2-[Fluorine-18]fluoro-2-deoxy- d -glucose PET
Shulkin, B. L., Thompson, N. W., Shapiro, B., Francis, I. R., & Sisson, J. C. (1999) · Radiology · doi:10.1148/radiology.212.1.r99jl3035 · Cited by 303 · see citing works
A case for clarity, consistency, and helpfulness: state-of-the-art clinical practice guidelines in endocrinology using the grading of recommendations, assessment, development, and evaluation system.
Swiglo, B. A., Murad, M. H., Schünemann, H. J., Kunz, R., Vigersky, R. A., Guyatt, G. H., & Montori, V. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1907 · Cited by 302 · see citing works
Self-citation
Clinically Guided Genetic Screening in a Large Cohort of Italian Patients with Pheochromocytomas and/or Functional or Nonfunctional Paragangliomas
Mannelli, M., Castellano, M., Schiavi, F., Filetti, S., Giacchè, M., Mori, L., Pignataro, V., Bernini, G., Giaché, V., Bacca, A., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2419 · Cited by 300 · see citing works
Cardiovascular manifestations of phaeochromocytoma
Prejbisz, A., Lenders, J. W. M., Eisenhofer, G., & Januszewicz, A. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834a4ce9 · Cited by 292 · see citing works
Self-citation
Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma
Eisenhofer, G., Lenders, J. W., Timmers, H., Mannelli, M., Grebe, S. K., Hofbauer, L. C., Bornstein, S. R., Tiebel, O., Adams, K., Bratslavsky, G., et al. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.153320 · Cited by 290 · see citing works
Self-citation
An Update on the Genetics of Paraganglioma, Pheochromocytoma, and Associated Hereditary Syndromes
Gimenez‐Roqueplo, A., Dahia, P. L. M., & Robledo, M. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0031-1301302 · Cited by 289 · see citing works
Self-citation
Clinical Presentations, Biochemical Phenotypes, and Genotype-Phenotype Correlations in Patients withSuccinate Dehydrogenase Subunit B-Associated Pheochromocytomas and Paragangliomas
Timmers, H. J. L. M., Kozupa, A., Eisenhofer, G., Raygada, M. J., Adams, K. T., Solis, D. C., Lenders, J. W. M., & Pacák, K. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2315 · Cited by 278 · see citing works
Self-citation
Staging and Functional Characterization of Pheochromocytoma and Paraganglioma by 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography
Timmers, H. J. L. M., Chen, C. C., Carrasquillo, J. A., Whatley, M. A., Ling, A. L., Eisenhofer, G., King, K. S., Rao, J. U., WESLEY, R. A., Adams, K. T., et al. (2012) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djs188 · Cited by 278 · see citing works
Self-citation
SDHA immunohistochemistry detects germline SDHA gene mutations in apparently sporadic paragangliomas and pheochromocytomas
Korpershoek, E., Favier, J., Gaal, J., Burnichon, N., van Gessel, B., Oudijk, L., Badoual, C., Gadessaud, N., Venisse, A., Bayley, J.-P., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1043 · Cited by 277 · see citing works
Self-citation
A pharmacological guide to medicines which interfere with the biodistribution of radiolabelled meta-iodobenzylguanidine (MIBG)
SOLANKP, K. K., Bomanji, J., Moyes, J. S. E., et al. (1992) · Nuclear Medicine Communications · doi:10.1097/00006231-199207000-00006 · Cited by 277 · see citing works
Perioperative management of pheochromocytoma
Kinney, M. A. O., Narr, B. J., & Warner, M. A. A. (2002) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/jcan.2002.124150 · Cited by 277 · see citing works
SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma
Bayley, J., Kunst, H. P. M., Cascón, A., Sampietro, M. L., Gaal, J., Korpershoek, E., Hinojar‐Gutiérrez, A., Timmers, H. J. L. M., Hoefsloot, L. H., Hermsen, M. A. J. A., et al. (2010) · The Lancet Oncology · doi:10.1016/s1470-2045(10)70007-3 · Cited by 275 · see citing works
Self-citation
SDH mutations in tumorigenesis and inherited endocrine tumours: lesson from the phaeochromocytoma–paraganglioma syndromes
Pasini, B., & Stratakis, C. A. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02111.x · Cited by 268 · see citing works
Genotype-phenotype correlations in von Hippel-Lindau disease
Ong, K. R., Woodward, E. R., Killick, P., Lim, C., MacDonald, F., & Maher, E. R. (2006) · Human Mutation · doi:10.1002/humu.20385 · Cited by 250 · see citing works
Secondary Hypertension in a Blood Pressure Clinic
Sinclair, A. (1987) · Archives of Internal Medicine · doi:10.1001/archinte.1987.00370070103015 · Cited by 243 · see citing works
Plasma Metanephrines Are Markers of Pheochromocytoma Produced by Catechol- O -Methyltransferase Within Tumors
Eisenhofer, G., Keiser, H. R., Friberg, P., Mezey, É., Huynh, T., Hiremagalur, B., Ellingson, T., Duddempudi, S., Eijsbouts, A. M. M., & Lenders, J. W. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.6.4870 · Cited by 242 · see citing works
Self-citation
Plasma Metanephrines in the Diagnosis of Pheochromocytoma
Lenders, J. W. M., Keiser, H. R., Goldstein, D. S., Willemsen, J. J., Friberg, P., Jacobs, M.-C., Kloppenborg, P. W. C., Thien, T., & Eisenhofer, G. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-2-199507150-00004 · Cited by 242 · see citing works
Self-citation
Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants
Houdayer, C., Caux-Moncoutier, V., Krieger, S., Barrois, M., Bonnet, F., Bourdon, V., Bronner, M., Buisson, M., Coulet, F., Gaildrat, P., et al. (2012) · Human Mutation · doi:10.1002/humu.22101 · Cited by 239 · see citing works
Determination of metanephrines in plasma by liquid chromatography with electrochemical detection
Lenders, J. W. M., Eisenhofer, G., Armando, I., Keiser, H. R., Goldstein, D. S., & Kopin, I. J. (1993) · Clinical Chemistry · doi:10.1093/clinchem/39.1.97 · Cited by 220 · see citing works
Self-citation
Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma
Eisenhofer, G., Pacák, K., Huynh, T.-T., Qin, N., Bratslavsky, G., Linehan, W. M., Mannelli, M., Friberg, P., Grebe, S. K., Timmers, H. J. L. M., et al. (2010) · Endocrine Related Cancer · doi:10.1677/erc-10-0211 · Cited by 206 · see citing works
Self-citation
Spectrum and Prevalence of FP/TMEM127 Gene Mutations in Pheochromocytomas and Paragangliomas
Yao, L., Schiavi, F., Cascón, A., Qin, Y., Inglada‐Pérez, L., King, E. E., Toledo, R. A., Ercolino, T., Rapizzi, E., Ricketts, C. J., et al. (2010) · JAMA · doi:10.1001/jama.2010.1830 · Cited by 201 · see citing works
Outcomes From 3144 Adrenalectomies in the United States: Which Matters More, Surgeon Volume or Specialty?
Park, H. S. (2009) · Archives of Surgery · doi:10.1001/archsurg.2009.191 · Cited by 201 · see citing works
Factors Associated with Perioperative Morbidity and Mortality in Patients with Pheochromocytoma: Analysis of 165 Operations at a Single Center1
Plouin, P., Duclos, J. M., Soppelsa, F., Boublil, G., & Châtellier, G. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.4.7392 · Cited by 201 · see citing works
Is laparoscopic adrenalectomy indicated for pheochromocytomas?
Gagner, M., Breton, G., Pharand, D., & Pomp, A. (1996) · Surgery · doi:10.1016/s0039-6060(96)80058-4 · Cited by 195 · see citing works
Phaeochromocytomas discovered during coronial autopsies in Sydney, Melbourne and Auckland
McNeil, A. R., Blok, B., Koelmeyer, T. D., et al. (2000) · Australian and New Zealand Journal of Medicine · doi:10.1111/j.1445-5994.2000.tb04358.x · Cited by 195 · see citing works
A single pediatric center experience with 1025 children with hypertension
Wyszyńska, T., Cichocka, E., Wieteska-Klimczak, A., et al. (1992) · Acta Paediatrica · doi:10.1111/j.1651-2227.1992.tb12213.x · Cited by 193 · see citing works
Pheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintigraphy.
Quint, L. E., Glazer, G. M., Francis, I. R., et al. (1987) · Radiology · doi:10.1148/radiology.165.1.3628794 · Cited by 193 · see citing works
Metastatic Pheochromocytoma/Paraganglioma Related to Primary Tumor Development in Childhood or Adolescence: Significant Link to SDHB Mutations
King, K. S., Prodanov, T., Kantorovich, V., Fojo, T., Hewitt, J. K., Zacharin, M., WESLEY, R. A., Lodish, M. B., Raygada, M. J., Gimenez‐Roqueplo, A., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.34.6353 · Cited by 193 · see citing works
Self-citation
Comparison of CT Findings in Symptomatic and Incidentally Discovered Pheochromocytomas
Motta-Ramírez, G. A., Remer, E. M., Herts, B. R., et al. (2005) · American Journal of Roentgenology · doi:10.2214/ajr.185.3.01850684 · Cited by 191 · see citing works
Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Neumann, H. P. H., Erlic, Z., Boedeker, C. C., Rybicki, L. A., Robledo, M., Hermsen, M. A. J. A., Schiavi, F., Falcioni, M., Kwok, P., Bauters, C., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4057 · Cited by 191 · see citing works
Laparoscopic and Retroperitoneoscopic Treatment of Pheochromocytomas and Retroperitoneal Paragangliomas: Results of 161 Tumors in 126 Patients
Walz, M. K., Alesina, P. F., Wenger, F. A., Koch, J. A., Neumann, H. P. H., Petersenn, S., Schmid, K. W., & Mann, K. (2006) · World Journal of Surgery · doi:10.1007/s00268-005-0373-6 · Cited by 187 · see citing works
Prospective evaluation of 100 robotic-assisted unilateral adrenalectomies
Brunaud, L., Ayav, A., Zarnegar, R., Rouers, A., Klein, M., Boissel, P., & Bresler, L. (2008) · Surgery · doi:10.1016/j.surg.2008.08.032 · Cited by 186 · see citing works
Health Supervision for Children With Neurofibromatosis
Hersh, J. H. (2008) · PEDIATRICS · doi:10.1542/peds.2007-3364 · Cited by 184 · see citing works
Efficacy and Safety of Doxazosin for Perioperative Management of Patients with Pheochromocytoma
Prys-Roberts, C., & Farndon, J. R. (2002) · World Journal of Surgery · doi:10.1007/s00268-002-6667-z · Cited by 183 · see citing works
Understanding Catecholamine Metabolism as a Guide to the Biochemical Diagnosis of Pheochromocytoma
Eisenhofer, G., Huynh, T., Hiroi, M., & Pacák, K. (2001) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1011572617314 · Cited by 182 · see citing works
Self-citation
Regional release and removal of catecholamines and extraneuronal metabolism to metanephrines.
Eisenhofer, G., Rundquist, B., Åneman, A., Friberg, P., Dakak, N., Kopin, I. J., Jacobs, M. C., & Lenders, J. W. M. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.10.7559889 · Cited by 181 · see citing works
Self-citation
Diagnostic Efficacy of Unconjugated Plasma Metanephrines for the Detection of Pheochromocytoma
Raber, W., Raffesberg, W., Bischof, M. G., Scheuba, C., Niederle, B., Gasic, S., Waldhäusl, W. K., & Roden, M. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.19.2957 · Cited by 180 · see citing works
Clinical Predictors and Algorithm for the Genetic Diagnosis of Pheochromocytoma Patients
Erlic, Z., Rybicki, L. A., Pęczkowska, M., Golcher, H., Kann, P. H., Brauckhoff, M., Müssig, K., Muresan, M., Schäffler, A., Reisch, N., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-1237 · Cited by 175 · see citing works
Preoperative and operative management of patients with phaeochromocytoma.
Ross, E. J., Prichard, B. N. C., Kaufman, L., et al. (1967) · BMJ · doi:10.1136/bmj.1.5534.191 · Cited by 174 · see citing works
A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma
Lorenzo, F. R., Yang, C., Ng Tang Fui, M., Vankayalapati, H., Zhuang, Z., Huynh, T., Grossmann, M., Pacak, K., & Prchal, J. T. (2013) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0967-z · Cited by 171 · see citing works
Self-citation
The volume‐outcome relation in the surgical treatment of esophageal cancer
Wouters, M. W. J. M., Gooiker, G. A., van Sandick, J. W., et al. (2011) · Cancer · doi:10.1002/cncr.26383 · Cited by 170 · see citing works
Metyrosine and Pheochromocytoma
Steinsapir, J. (1997) · Archives of Internal Medicine · doi:10.1001/archinte.1997.00440290087009 · Cited by 170 · see citing works
Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis
Comino-Méndez, I., de Cubas, A. A., Bernal, C., Álvarez-Escolá, C., Sánchez-Malo, C., Ramírez-Tortosa, C. L., Pedrinaci, S., Rapizzi, E., Ercolino, T., Bernini, G., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt069 · Cited by 169 · see citing works
Low-Density Pheochromocytoma on CT:A Mimicker of Adrenal Adenoma
Blake, M. A., Krishnamoorthy, S. K., Boland, G. W., Sweeney, A. T., Pitman, M. B., Harisinghani, M., Mueller, P. R., & Hahn, P. F. (2003) · American Journal of Roentgenology · doi:10.2214/ajr.181.6.1811663 · Cited by 166 · see citing works
High Incidence of Cardiovascular Complications in Pheochromocytoma
Zelinka, T., Petrák, O., Turková, H., et al. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0032-1306294 · Cited by 166 · see citing works
Usefulness of 123I-MIBG Scintigraphy in the Evaluation of Patients with Known or Suspected Primary or Metastatic Pheochromocytoma or Paraganglioma: Results from a Prospective Multicenter Trial
Wiseman, G. A., Pacák, K., O'Dorisio, M. S., et al. (2009) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.058701 · Cited by 161 · see citing works
SUCCESSFUL OUTCOMES IN PHEOCHROMOCYTOMA SURGERY IN THE MODERN ERA
ULCHAKER, J. C., Goldfarb, D. A., Bravo, E. L., & Novick, A. C. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(01)61762-2 · Cited by 160 · see citing works
Is the Excess Cardiovascular Morbidity in Pheochromocytoma Related to Blood Pressure or to Catecholamines?
Stolk, R. F., Bakx, C., Mulder, J., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3669 · Cited by 160 · see citing works
18F-DOPA positron emission tomography for the detection of glomus tumours
Hoegerle, S., Ghanem, N., Altehoefer, C., Schipper, J., Brink, I., Moser, E. A., & Neumann, H. P. H. (2003) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-003-1115-3 · Cited by 160 · see citing works
Pheochromocytoma Crisis Is Not a Surgical Emergency
Scholten, A., Cisco, R. M., Vriens, M. R., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3020 · Cited by 158 · see citing works
123I-Meta-Iodobenzylguanidine Scintigraphy for the Detection of Neuroblastoma and Pheochromocytoma: Results of a Meta-Analysis
Jacobson, A. F., Deng, H., Lombard, J., Lessig, H. J., & Black, R. R. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2604 · Cited by 157 · see citing works
New Syndrome of Paraganglioma and Somatostatinoma Associated With Polycythemia
Pacák, K., Jochmanová, I., Prodanov, T., Yang, C., Merino, M. J., Fojo, T., Prchal, J. T., Tischler, A. S., Lechan, R. M., & Zhuang, Z. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.47.1912 · Cited by 156 · see citing works
6-[F-18]Fluoro- l -Dihydroxyphenylalanine Positron Emission Tomography Is Superior to Conventional Imaging with 123I-Metaiodobenzylguanidine Scintigraphy, Computer Tomography, and Magnetic Resonance Imaging in Localizing Tumors Causing Catecholamine Excess
Fiebrich, H., Brouwers, A. H., Kerstens, M. N., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1054 · Cited by 155 · see citing works
The effect of calcium channel blockers on outcome following the surgical treatment of phaeochromocytomas and paragangliomas
Lebuffe, G., Dosseh, E. D. J., Tek, G., et al. (2005) · Anaesthesia · doi:10.1111/j.1365-2044.2005.04156.x · Cited by 153 · see citing works
Adrenal pheochromocytoma remains a frequently overlooked diagnosis
Lo, C., Lam, K.-Y., Wat, M. S., et al. (2000) · The American Journal of Surgery · doi:10.1016/s0002-9610(00)00296-8 · Cited by 152 · see citing works
Imaging Work-Up for Screening of Paraganglioma and Pheochromocytoma inSDHxMutation Carriers: A Multicenter Prospective Study from the PGL.EVA Investigators
Gimenez‐Roqueplo, A., Caumont‐Prim, A., Houzard, C., Hignette, C., Hernigou, A., Halimi, P., Niccoli, P., Leboulleux, S., Amar, L., Borson‐Chazot, F., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2975 · Cited by 152 · see citing works
Self-citation
Comparison of Two Preoperative Medical Management Strategies for Laparoscopic Resection of Pheochromocytoma
Weingarten, T. N., Cata, J. P., O’Hara, J. F., Prybilla, D., Pike, T. L., Thompson, G. B., Grant, C. S., Warner, D. O., Bravo, E. L., & Šprung, J. (2010) · Urology · doi:10.1016/j.urology.2010.03.032 · Cited by 151 · see citing works
Effectiveness and limits of preoperative imaging studies for the localisation of pheochromocytomas and paragangliomas: a review of 282 cases
Jalil, N. D., Pattou, F. N., Combemale, F., Chapuis, Y., Henry, J., Peix, J., & Proye, C. A. G. (2002) · The European Journal of Surgery · doi:10.1080/110241598750004913 · Cited by 150 · see citing works
Dietary Influences on Plasma and Urinary Metanephrines: Implications for Diagnosis of Catecholamine-Producing Tumors
de Jong, W. H. A., Eisenhofer, G., Post, W. J., Muskiet, F. A. J., de Vries, E. G. E., & Kema, I. P. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0303 · Cited by 150 · see citing works
Self-citation
Comparison of 6-18F-Fluorodopamine PET with 123I-Metaiodobenzylguanidine and 111In-Pentetreotide Scintigraphy in Localization of Nonmetastatic and Metastatic Pheochromocytoma
Ilias, Ι., Chen, C. C., Carrasquillo, J. A., et al. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.052373 · Cited by 150 · see citing works
Risk of malignant paraganglioma in SDHB-mutation and SDHD-mutation carriers: a systematic review and meta-analysis
van Hulsteijn, L. T., Dekkers, O. M., Hes, F. J., Smit, J. W. A., & Corssmit, E. P. M. (2012) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2012-101192 · Cited by 149 · see citing works
Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma
Burnichon, N., Buffet, A., Parfait, B., Letouzé, É., Laurendeau, I., Loriot, C., Pasmant, É., Abermil, N., Valeyrie‐Allanore, L., Bertherat, J. Y., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds374 · Cited by 147 · see citing works
Self-citation
Plasma Free Metanephrine Measurement Using Automated Online Solid-Phase Extraction HPLC–Tandem Mass Spectrometry
de Jong, W. H. A., Graham, K. S., van der Molen, J. C., Links, T. P., Morris, M. R., Ross, H. A., de Vries, E. G. E., & Kema, I. P. (2007) · Clinical Chemistry · doi:10.1373/clinchem.2007.087114 · Cited by 146 · see citing works
Factors Associated with Perioperative Morbidity and Mortality in Patients with Pheochromocytoma: Analysis of 165 Operations at a Single Center
Plouin, P. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.4.1480 · Cited by 146 · see citing works
Point of controversy: perioperative care of patients undergoing pheochromocytoma removal–time for a reappraisal?
Lentschener, C., Gaujoux, S., Tesnière, A., & Dousset, B. E. (2011) · European Journal of Endocrinology · doi:10.1530/eje-11-0162 · Cited by 139 · see citing works
Functional Imaging ofSDHx-Related Head and Neck Paragangliomas: Comparison of18F-Fluorodihydroxyphenylalanine,18F-Fluorodopamine,18F-Fluoro-2-Deoxy- d -Glucose PET,123I-Metaiodobenzylguanidine Scintigraphy, and111In-Pentetreotide Scintigraphy
King, K. S., Chen, C. C., Alexopoulos, D. K., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0333 · Cited by 138 · see citing works
False-negative 123I-MIBG SPECT is most commonly found in SDHB-related pheochromocytoma or paraganglioma with high frequency to develop metastatic disease
Fonte, J. S., Robles, J., Chen, C. C., Reynolds, J. C., Whatley, M. A., Ling, A. L., MERCADO-ASIS, L. B., Adams, K. T., Martucci, V. L., Fojo, T., et al. (2011) · Endocrine Related Cancer · doi:10.1530/erc-11-0243 · Cited by 137 · see citing works
CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas)
Sahdev, A., Sohaib, A., Monson, J. P., Grossman, A. B., Chew, S. L., & Reznek, R. H. (2004) · European Radiology · doi:10.1007/s00330-004-2412-3 · Cited by 135 · see citing works
Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass
Unger, N., Pitt, C., Schmidt, I. L., Walz, M. K., Schmid, K. W., Philipp, T., Mann, K., & Petersenn, S. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02097 · Cited by 135 · see citing works
Genetics of Pheochromocytoma and Paraganglioma in Spanish Patients
Cascón, A., Pita, G., Burnichon, N., Landa, I., López-Jiménez, E. A., Montero‐Conde, C., Leskelä, S., Leandro-Garcia, L. J., Letón, R., Rodríguez‐Antona, C., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2756 · Cited by 134 · see citing works
Self-citation
6- 18 F-Fluoro- l -Dihydroxyphenylalanine Positron Emission Tomography Is Superior to 123 I-Metaiodobenzyl-Guanidine Scintigraphy in the Detection of Extraadrenal and Hereditary Pheochromocytomas and Paragangliomas: Correlation with Vesicular Monoamine Transporter Expression
Fottner, C., Helisch, A., Anlauf, M., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2352 · Cited by 133 · see citing works
Pheochromocytoma: effect of nonionic contrast medium in CT on circulating catecholamine levels.
Mukherjee, J. J., Peppercorn, P. D., Reznek, R. H., et al. (1997) · Radiology · doi:10.1148/radiology.202.1.8988215 · Cited by 132 · see citing works
Clinical aspects of SDHx-related pheochromocytoma and paraganglioma
Timmers, H. J. L. M., Gimenez‐Roqueplo, A., Mannelli, M., & Pacák, K. (2009) · Endocrine Related Cancer · doi:10.1677/erc-08-0284 · Cited by 131 · see citing works
Self-citation
123I‐metaiodobenzylguanidine (MIBG) scintigraphy for the detection of adrenal and extra‐adrenal phaeochromocytomas: CT and MRI correlation
Bhatia, K. S. S., Ismail, M., Sahdev, A., Rockall, A., Hogarth, K. M., Canizales, A., Avril, N. E., Monson, J. P., Grossman, A. B., & Reznek, R. H. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03256.x · Cited by 127 · see citing works
Measurement of Plasma Free Metanephrine and Normetanephrine by Liquid Chromatography–Tandem Mass Spectrometry for Diagnosis of Pheochromocytoma
Lagerstedt, S. A., O’Kane, D. J., & Singh, R. J. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2003.024703 · Cited by 127 · see citing works
Iodine-131-metaiodobenzylguanidine scintigraphy in preoperative and postoperative evaluation of paragangliomas: comparison with CT and MRI.
Maurea, S., Cuocolo, A., Reynolds, J. C., et al. (1993) · PubMed · Cited by 127 · see citing works
18F-FDG Avidity of Pheochromocytomas and Paragangliomas: A New Molecular Imaging Signature?
Taïeb, D., Sebag, F. A., Barlier, A., Tessonnier, L., Palazzo, F. F., Morange, I., Niccoli, P., Fakhry, N., Micco, C. D., Cammilleri, S., et al. (2009) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.060731 · Cited by 126 · see citing works
Isocitrate Dehydrogenase Mutations Are Rare in Pheochromocytomas and Paragangliomas
Gaal, J., Burnichon, N., Korpershoek, E., Roncelin, I., Bertherat, J. Y., Plouin, P., de Krijger, R. R., Gimenez‐Roqueplo, A., & Dinjens, W. N. M. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2170 · Cited by 126 · see citing works
Self-citation
Adrenal phaeochromocytoma: correlation of MRI appearances with histology and function
Jacques, A., Sahdev, A., Sandrasagara, M., Goldstein, R., Berney, D. M., Rockall, A., Chew, S. L., & Reznek, R. H. (2008) · European Radiology · doi:10.1007/s00330-008-1073-z · Cited by 126 · see citing works
Biochemically Silent Abdominal Paragangliomas in Patients with Mutations in the Succinate Dehydrogenase Subunit B Gene
Timmers, H. J. L. M., Pacák, K., Huynh, T., Abu-Asab, M. S., Tsokos, M., Merino, M. J., Baysal, B. E., Adams, K. T., & Eisenhofer, G. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1093 · Cited by 124 · see citing works
Self-citation
One Hundred Two Patients With Pheochromocytoma Treated at a Single Institution Since the Introduction of Laparoscopic Adrenalectomy
Shen, W. T. (2010) · Archives of Surgery · doi:10.1001/archsurg.2010.159 · Cited by 123 · see citing works
Metastatic Pheochromocytoma and Paraganglioma: Focus on Therapeutics
Plouin, P., Fitzgerald, P., Rich, T. A., et al. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0031-1299707 · Cited by 120 · see citing works
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatographytandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma
Peitzsch, M., Prejbisz, A., Kroiß, M., Beuschlein, F., Arlt, W., Januszewicz, A., Siegert, G., & Eisenhofer, G. (2013) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012112 · Cited by 120 · see citing works
Self-citation
Performance of plasma free metanephrines measured by liquid chromatography–tandem mass spectrometry in the diagnosis of pheochromocytoma
Peaston, R., Graham, K. S., Chambers, E. E., van der Molen, J. C., & Ball, S. L. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.01.012 · Cited by 120 · see citing works
Comparison of Diagnostic Accuracy of Urinary Free Metanephrines, Vanillyl Mandelic Acid, and Catecholamines and Plasma Catecholamines for Diagnosis of Pheochromocytoma
Boyle, J. G., Davidson, D. F., Perry, C. G., & Connell, J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2668 · Cited by 120 · see citing works
Is Supine Rest Necessary before Blood Sampling for Plasma Metanephrines?
Lenders, J. W. M., Willemsen, J. J., Eisenhofer, G., Ross, H. A., Pacák, K., Timmers, H. J. L. M., & Sweep, F. C. G. J. (2007) · Clinical Chemistry · doi:10.1373/clinchem.2006.076489 · Cited by 120 · see citing works
Self-citation
A Decade (2001-2010) of Genetic Testing for Pheochromocytoma and Paraganglioma
Buffet, A., Vénisse, A., Nau, V., et al. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0032-1304594 · Cited by 119 · see citing works
Estimated Risk of Pheochromocytoma Recurrence After Adrenal-Sparing Surgery in Patients With Multiple Endocrine Neoplasia Type 2A
Asari, R. (2006) · Archives of Surgery · doi:10.1001/archsurg.141.12.1199 · Cited by 118 · see citing works
111In-Octreotide Is Superior to 123I-Metaiodobenzylguanidine for Scintigraphic Detection of Head and Neck Paragangliomas
Koopmans, K. P., Jager, P. L., Kema, I. P., et al. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.047738 · Cited by 116 · see citing works
Iatrogenic pheochromocytomatosis: A previously unreported result of laparoscopic adrenalectomy
Li, M. L., Fitzgerald, P. A., Price, D. C., et al. (2001) · Surgery · doi:10.1067/msy.2001.118373 · Cited by 115 · see citing works
Diagnosis of pheochromocytoma using [123I]‐ compared with [131I]‐metaiodobenzylguanidine scintigraphy
Furuta, N., Kiyota, H., Yoshigoe, F., Hasegawa, N., & Ohishi, Y. (1999) · International Journal of Urology · doi:10.1046/j.1442-2042.1999.06310.x · Cited by 114 · see citing works
Role of Noncoding RNA ANRIL in Genesis of Plexiform Neurofibromas in Neurofibromatosis Type 1
Pasmant, É., Sabbagh, A., Masliah‐Planchon, J., Ortonne, N., Laurendeau, I., Melin, L., Ferkal, S., Hernandez, L., Leroy, K., Valeyrie‐Allanore, L., et al. (2011) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djr416 · Cited by 114 · see citing works
Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma
Eisenhofer, G., Lattke, P., Herberg, M., Siegert, G., Qin, N., Därr, R., Hoyer, J., Villringer, A., Prejbisz, A., Januszewicz, A., et al. (2013) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012066 · Cited by 113 · see citing works
Sensitivity and positive predictive value of CT, MRI and 123I-MIBG scintigraphy in localizing pheochromocytomas: A prospective study
Lumachi, F., Tregnaghi, A., Zucchetta, P., Marzola, M. C., Cecchin, D., Grassetto, G., & Bui, F. (2006) · Nuclear Medicine Communications · doi:10.1097/00006231-200607000-00006 · Cited by 113 · see citing works
The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma
Perry, C. G., Sawka, A. M., Singh, R., Thabane, L., Bajnárek, J., & Young, W. F. (2007) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2007.02805.x · Cited by 111 · see citing works
Self-citation
Age at Diagnosis of Pheochromocytoma Differs According to Catecholamine Phenotype and Tumor Location
Eisenhofer, G., Timmers, H. J. L. M., Lenders, J. W. M., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1588 · Cited by 111 · see citing works
Self-citation
Diagnostic Tests and Biomarkers for Pheochromocytoma and Extra-adrenal Paraganglioma: From Routine Laboratory Methods to Disease Stratification
Eisenhofer, G., Tischler, A. S., & de Krijger, R. R. (2011) · Endocrine Pathology · doi:10.1007/s12022-011-9188-1 · Cited by 111 · see citing works
Self-citation
Surgical Management of Pheochromocytoma with the Use of Metyrosine
Perry, R. R., Keiser, H. R., Norton, J. A., et al. (1990) · Annals of Surgery · doi:10.1097/00000658-199011000-00010 · Cited by 111 · see citing works
Urinary and plasma catecholamines and urinary catecholamine metabolites in pheochromocytoma: diagnostic value in 19 cases
Gerlo, E., & Sevens, C. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.2.250 · Cited by 110 · see citing works
Plasma free metanephrines are superior to urine and plasma catecholamines and urine catecholamine metabolites for the investigation of phaeochromocytoma
Hickman, P. E., Leong, M., Chang, J., Wilson, S. R., & McWhinney, B. C. (2009) · Pathology · doi:10.1080/00313020802579284 · Cited by 109 · see citing works
The Protean Manifestations of Pheochromocytoma
Manger, W. M. (2009) · Hormone and Metabolic Research · doi:10.1055/s-0028-1128139 · Cited by 107 · see citing works
Plasma Chromogranin A or Urine Fractionated Metanephrines Follow-Up Testing Improves the Diagnostic Accuracy of Plasma Fractionated Metanephrines for Pheochromocytoma
Algeciras‐Schimnich, A., Preissner, C. M., Young, W. F., Singh, R. J., & Grebe, S. K. G. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1354 · Cited by 106 · see citing works
Self-citation
Partial Adrenalectomy: Underused First Line Therapy for Small Adrenal Tumors
Kaye, D. R., Storey, B., Pacák, K., Pinto, P. A., Linehan, W. M., & Bratslavsky, G. (2010) · The Journal of Urology · doi:10.1016/j.juro.2010.03.052 · Cited by 105 · see citing works
Diagnostic accuracy of free and total metanephrines in plasma and fractionated metanephrines in urine of patients with pheochromocytoma
Grouzmann, E., Drouard-Troalen, L., Baudin, É., Plouin, P., Müller-Stich, B. P., Grand, D., & Buclin, T. (2010) · European Journal of Endocrinology · doi:10.1530/eje-09-0996 · Cited by 105 · see citing works
Critical size of residual adrenal tissue and recovery from impaired early postoperative adrenocortical function after subtotal bilateral adrenalectomy
Brauckhoff, M. (2003) · Surgery · doi:10.1016/j.surg.2003.08.005 · Cited by 105 · see citing works
Drugs and Pheochromocytoma — Don't Be Fooled by Every Elevated Metanephrine
Neary, N. M., King, K. S., & Pacák, K. (2011) · New England Journal of Medicine · doi:10.1056/nejmc1101502 · Cited by 105 · see citing works
Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy for pheochromocytoma
Dickson, P. V., Alex, G. C., Grubbs, E. G., et al. (2011) · Surgery · doi:10.1016/j.surg.2011.07.004 · Cited by 103 · see citing works
Drugs and pheochromocytoma--don't be fooled by every elevated metanephrine.
Neary, N. M., King, K. S., & Pacák, K. (2011) · PubMed · doi:10.1056/nejmc1101502#sa1 · Cited by 102 · see citing works
Simultaneous liquid chromatography tandem mass spectrometric determination of urinary free metanephrines and catecholamines, with comparisons of free and deconjugated metabolites
Peitzsch, M., Pelzel, D., Glöckner, S., Prejbisz, A., Faßnacht, M., Beuschlein, F., Januszewicz, A., Siegert, G., & Eisenhofer, G. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2012.12.031 · Cited by 99 · see citing works
Self-citation
The efficacy of iodine-123-MIBG as a screening test for pheochromocytoma.
Mozley, P. D., Kim, C. K., Mohsin, J., et al. (1994) · PubMed · Cited by 97 · see citing works
Long-Term Outcomes of Surgical Treatment for Hereditary Pheochromocytoma
Grubbs, E. G., Rich, T. A., Ng, C. S., Bhosale, P., Jiménez, C., Evans, D. B., Lee, J. E., & Perrier, N. D. (2013) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2012.10.012 · Cited by 96 · see citing works
Alpha blockade in preoperative preparation of patients with pheochromocytomas.
Koçak, S., Aydıntuğ, S., & Çanakçi, N. (2003) · PubMed · Cited by 91 · see citing works
Discordant localization of 2-[18F]-fluoro-2-deoxy-D-glucose in 6-[18F]-fluorodopamine- and [123I]-metaiodobenzylguanidine-negative metastatic pheochromocytoma sites
Mamede, M. H., Carrasquillo, J. A., Chen, C. C., et al. (2005) · Nuclear Medicine Communications · doi:10.1097/01.mnm.0000189780.54658.e8 · Cited by 91 · see citing works
Diagnostic imaging in patients with paragangliomas. Computed tomography, magnetic resonance and MIBG scintigraphy comparison.
Maurea, S., Cuocolo, A., Reynolds, J. C., Neumann, R. D., & Salvatore, M. (1996) · PubMed · Cited by 89 · see citing works
HYPERTENSIVE RESPONSE TO LABETALOL IN PHÆOCHROMOCYTOMA
BRIGGS, R. S. J., Birtwell, A. J., & Pohl, J. (1978) · The Lancet · doi:10.1016/s0140-6736(78)90772-9 · Cited by 87 · see citing works
Pheochromocytoma: value of computed tomography.
Welch, T. L., Sheedy, P. F., van Heerden, J. A., et al. (1983) · Radiology · doi:10.1148/radiology.148.2.6867349 · Cited by 85 · see citing works
Pheochromocytoma and paraganglioma: nimaging characteristics
Baez, J. C., Jagannathan, J. P., Krajewski, K. M., O'Regan, K. N., Zukotynski, K., Kulke, M. H., & Ramaiya, N. H. (2012) · Cancer Imaging · doi:10.1102/1470-7330.2012.0016 · Cited by 84 · see citing works
Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma
Eisenhofer, G., Huynh, T., ELKAHLOUN, A. G., Morris, J. C., Bratslavsky, G., Linehan, W. M., Zhuang, Z., Balgley, B. M., Lee, C. S., Mannelli, M., et al. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90591.2008 · Cited by 83 · see citing works
Self-citation
The role of 18 F‐FDOPA and 18 F‐FDG–PET in the management of malignant and multifocal phaeochromocytomas
Taïeb, D., Tessonnier, L., Sebag, F. A., Niccoli, P., Morange, I., Colavolpe, C., Micco, C. D., Barlier, A., Palazzo, F. F., Henry, J. F., et al. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03257.x · Cited by 82 · see citing works
Long-term Postoperative Follow-up in Patients with Apparently Benign Pheochromocytoma and Paraganglioma
Amar, L., Faßnacht, M., Gimenez‐Roqueplo, A., et al. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0031-1301339 · Cited by 80 · see citing works
Self-citation
Pheochromocytoma: Clinical Observations from a Brooklyn Tertiary Hospital
Ariton, M., JUAN, C. S., & AvRuskin, T. W. (2000) · Endocrine Practice · doi:10.4158/ep.6.3.249 · Cited by 79 · see citing works
Management and Treatment of Pheochromocytomas and Paragangliomas
Mannelli, M. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1353.044 · Cited by 78 · see citing works
Lipid Degeneration in Pheochromocytomas Mimicking Adrenal Cortical Tumors
Ramsay, J. A., Asa, S. L., Nostrand, A. W. P. V., et al. (1987) · The American Journal of Surgical Pathology · doi:10.1097/00000478-198706000-00009 · Cited by 78 · see citing works
Use of 6‐[18F]‐fluorodopamine positron emission tomography (PET) as first‐line investigation for the diagnosis and localization of non‐metastatic and metastatic phaeochromocytoma (PHEO)
Timmers, H. J. L. M., Eisenhofer, G., Carrasquillo, J. A., et al. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03496.x · Cited by 75 · see citing works
Self-citation
Preoperative pharmacological management of phaeochromocytoma.
van der Horst‐Schrivers, A. N. A., Kerstens, M. N., & Wolffenbuttel, B. H. R. (2006) · PubMed · Cited by 75 · see citing works
Preoperative alpha blockade for normotensive pheochromocytoma
Shao, Y., Chen, R., Shen, Z., et al. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834d24d9 · Cited by 73 · see citing works
Functional and Oncologic Outcomes of Partial Adrenalectomy for Pheochromocytoma in Patients With von Hippel-Lindau Syndrome After at Least 5 Years of Followup
Benhammou, J. N., Boris, R. S., Pacák, K., et al. (2010) · The Journal of Urology · doi:10.1016/j.juro.2010.06.102 · Cited by 73 · see citing works
Evaluation of SDHB , SDHD and VHL gene susceptibility testing in the assessment of individuals with non‐syndromic phaeochromocytoma, paraganglioma and head and neck paraganglioma
Jafri, M., Whitworth, J., Rattenberry, E., Vialard, L., Kilby, G., Kumar, A., Izatt, L., Lalloo, F. I., Brennan, P., Cook, J. A., et al. (2012) · Clinical Endocrinology · doi:10.1111/cen.12074 · Cited by 73 · see citing works
[11C]Metahydroxyephedrine and [18F]Fluorodeoxyglucose Positron Emission Tomography Improve Clinical Decision Making in Suspected Pheochromocytoma
Mann, G. N., Link, J. M., Pham, P., et al. (2006) · Annals of Surgical Oncology · doi:10.1245/aso.2006.04.022 · Cited by 72 · see citing works
Current and Future Anatomical and Functional Imaging Approaches to Pheochromocytoma and Paraganglioma
Timmers, H. J. L. M., Taïeb, D., & Pacák, K. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0031-1299712 · Cited by 72 · see citing works
Pheochromocytomas and paragangliomas: assessment of malignant potential
Korevaar, T. I. M., & Grossman, A. B. (2011) · Endocrine · doi:10.1007/s12020-011-9545-3 · Cited by 70 · see citing works
Complications in laparoscopic adrenalectomy: the value of experience
Bergamini, C., Martellucci, J., Tozzi, F., et al. (2011) · Surgical Endoscopy · doi:10.1007/s00464-011-1804-0 · Cited by 70 · see citing works
Phaeochromocytoma in children
Armstrong, R., Sridhar, M., Greenhalgh, K. L., Howell, L., Jones, C., Landes, C. J., McPartland, J., Moores, C., Losty, P., & Didi, M. (2008) · Archives of Disease in Childhood · doi:10.1136/adc.2008.139121 · Cited by 70 · see citing works
Death from Phaeochromocytoma: Lessons from a Post-Mortem Survey
Platts, J. K., Drew, P. J., & Harvey, J. N. (1995) · Journal of the Royal College of Physicians of London · doi:10.1016/s0035-8819(25)00567-7 · Cited by 69 · see citing works
Free plasma metanephrines as a screening test for pheochromocytoma in low-risk patients
Václavík, J., Stejskal, D., Lačňák, B., Lazárová, M., Jedelský, L., Kadalová, L., Janošová, M., Fryšák, Z., & Vlček, P. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e32813aeb5a · Cited by 68 · see citing works
Metaiodobenzylguanidine (MIBG) scintigraphy and computed tomography (CT) in clinical practice. Primary and secondary evaluation for localization of phaeochromocytomas
Berglund, A. S., Hulthén, U. L., Manhem, P., et al. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00792.x · Cited by 68 · see citing works
Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas
Alesina, P. F., Hinrichs, J., Meier, B., et al. (2011) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-011-0851-2 · Cited by 67 · see citing works
Diagnosis and localization of pheochromocytoma
Ganguly, A., Henry, D. P., Yune, H. Y., et al. (1979) · The American Journal of Medicine · doi:10.1016/0002-9343(79)90064-0 · Cited by 66 · see citing works
False Positive test Results for Pheochromocytoma from 2000 to 2008
Yu, R., & Wei, M. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1237699 · Cited by 66 · see citing works
Pheochromocytoma and paraganglioma: imaging characteristics
Baez, J. C., Jagannathan, J. P., Krajewski, K. M., et al. (2012) · Cancer Imaging · doi:10.1102/1470-5206.2012.0016 · Cited by 66 · see citing works
HIF2AMutations in Paraganglioma with Polycythemia
Favier, J., Buffet, A., & Gimenez‐Roqueplo, A. (2012) · New England Journal of Medicine · doi:10.1056/nejmc1211953 · Cited by 65 · see citing works
Self-citation
Influence of various confounding variables and storage conditions on metanephrine and normetanephrine levels in plasma
Deutschbein, T., Unger, N., Jaeger, A., Broecker‐Preuss, M., Mann, K., & Petersenn, S. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03761.x · Cited by 64 · see citing works
Value of 123I-MIBG Scintigraphy in Paraganglioma
Milardović, R., Corssmit, E. P. M., & Stokkel, M. P. M. (2009) · Neuroendocrinology · doi:10.1159/000242499 · Cited by 64 · see citing works
TMEM127Screening in a Large Cohort of Patients with Pheochromocytoma and/or Paraganglioma
Abermil, N., Guillaud-Bataille, M., Burnichon, N., Vénisse, A., Manivet, P., Guignat, L., Drui, D., Chupin, M., Josseaume, C., Affres, H., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3360 · Cited by 64 · see citing works
Self-citation
Clinical value of 18F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET/CT) for detecting pheochromocytoma
Luster, M., Karges, W., Zeich, K., et al. (2009) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-009-1294-7 · Cited by 64 · see citing works
Mortality associated with pheochromocytoma in a large Swedish cohort
Khorram‐Manesh, A., Ahlman, H. K., Nilsson, O., et al. (2004) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2004.03.006 · Cited by 64 · see citing works

Flagged first, then by citations

Research works printed but not linked: 5

Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromo- cytoma. Lancet. 2005;366:665-675.
Prejbisz A, Lenders JW, Eisenhofer G, Januszewicz A. Cardiovas- cular manifestations of phaeochromocytoma. J Hypertens. 2011; 29:2049 -2060.
Manu P, Runge LA. Biochemical screening for pheochromocy- toma. Superiority of urinary metanephrines measurements. Am J Epidemiol. 1984;120:788 -790.
Därr R, Lenders JW, Stange K, et al. Diagnosis of pheochromocy- toma and paraganglioma: the clonidine suppression test in patients with borderline elevations of plasma free normetanephrine [in Ger- man]. Dtsch Med Wochenschr. 2013;138:76 -81.
Shao Y, Chen R, Shen ZJ, et al. Preoperative ␣ blockade for nor- motensive pheochromocytoma: is it necessary? J Hypertens. 2011; 29:2429 -2432.

Sorted by citations

2018 ESC/ESH Guidelines for the management of arterial hypertension
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy339 · Cited by 10,286 · see citing works
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391 · see citing works
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000066 · Cited by 4,347 · see citing works
2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001940 · Cited by 2,885 · see citing works
2024 ESC Guidelines for the management of elevated blood pressure and hypertension
McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C., Christodorescu, R. M., Daskalopoulou, S. S., Ferro, C. J., Gerdts, E., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae178 · Cited by 2,298 · see citing works
Management of adrenal incidentalomas: European society of endocrinology clinical practice guideline in collaboration with the European network for the study of adrenal tumors
Fassnacht, M., Arlt, W., Bancos, I., Dralle, H., Newell-Price, J., Sahdev, A., Tabarin, A., Terzolo, M., Tsagarakis, S., & Dekkers, O. M. (2016) · European Journal of Endocrinology · doi:10.1530/eje-16-0467 · Cited by 1,566 · see citing works
Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association
Carey, R. M., Calhoun, D. A., Bakris, G. L., Brook, R. D., Daugherty, S. L., Dennison-Himmelfarb, C. R., Egan, B. M., Flack, J. M., Gidding, S. S., Judd, E., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000084 · Cited by 1,153 · see citing works
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000596 · Cited by 1,127 · see citing works
Pheochromocytoma and Paraganglioma
Neumann, H. P. H., Young, W. F., & Eng, C. (2019) · New England Journal of Medicine · doi:10.1056/nejmra1806651 · Cited by 736 · see citing works
Self-citation
Adrenal incidentaloma
Sherlock, M., Scarsbrook, A., Abbas, A., Fraser, S., Limumpornpetch, P., Dineen, R., & Stewart, P. M. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa008 · Cited by 347 · see citing works
“%) mutations are the most frequent germline mutations in pheochromocytoma and paragangliomas (180).”
Background
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism
Lussey-Lepoutre, C., Hollinshead, K. E. R., Ludwig, C., Menara, M., Morin, A., Castro-Vega, L.-J., Parker, S. J., Janin, M., Martinelli, C., Ottolenghi, C., et al. (2015) · Nature Communications · doi:10.1038/ncomms9784 · Cited by 227 · see citing works
Self-citation
Approach to the Patient With Adrenal Incidentaloma
Bancos, I., & Prete, A. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab512 · Cited by 201 · see citing works
Biochemical diagnosis of chromaffin cell tumors in patients at high and low risk of disease: plasma versus urinary free or deconjugated O-methylated catecholamine metabolites
Eisenhofer, G., Prejbisz, A., Peitzsch, M., Pamporaki, C., Masjkur, J., Rogowski-Lehmann, N., Langton, K., Tsourdi, E., Pęczkowska, M., Fliedner, S., et al. (2018) · Clinical Chemistry · doi:10.1373/clinchem.2018.291369 · Cited by 181 · see citing works
Self-citation
Clinical guidelines for the management of adrenal incidentaloma
Lee, J.-M., Kim, M. K., Ko, S.-H., Koh, J.-M., Kim, B.-Y., Kim, S. W., Kim, S.-K., Kim, H. J., Ryu, O.-H., Park, J., et al. (2017) · Endocrinology and Metabolism · doi:10.3803/enm.2017.32.2.200 · Cited by 147 · see citing works
CT characteristics of pheochromocytoma: relevance for the evaluation of adrenal incidentaloma
Canu, L., Van Hemert, J. A. W., Kerstens, M. N., Hartman, R. P., Khanna, A., Kraljevic, I., Kastelan, D., Badiu, C., Ambroziak, U., Tabarin, A., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01532 · Cited by 131 · see citing works
Self-citation
Validation of pathological grading systems for predicting metastatic potential in pheochromocytoma and paraganglioma
Koh, J.-M., Ahn, S. H., Kim, H., Kim, B.-J., Sung, T.-Y., Kim, Y. H., Hong, S. J., Song, D. E., & Lee, S. H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187398 · Cited by 114 · see citing works
Accuracy of recommended sampling and assay methods for the determination of plasma-free and urinary fractionated metanephrines in the diagnosis of pheochromocytoma and paraganglioma: a systematic review
Därr, R., Kuhn, M., Bode, C., Bornstein, S. R., Pacak, K., Lenders, J. W. M., & Eisenhofer, G. (2017) · Endocrine · doi:10.1007/s12020-017-1300-y · Cited by 105 · see citing works
Management of endocrine disease: differential diagnosis, investigation and therapy of bilateral adrenal incidentalomas
Bourdeau, I., El Ghorayeb, N., Gagnon, N., & Lacroix, A. (2018) · European Journal of Endocrinology · doi:10.1530/eje-18-0296 · Cited by 98 · see citing works
Unenhanced CT imaging is highly sensitive to exclude pheochromocytoma: a multicenter study
Buitenwerf, E., Korteweg, T., Visser, A., Haag, C. M. S. C., Feelders, R. A., Timmers, H. J. L. M., Canu, L., Haak, H. R., Bisschop, P. H. L. T., Eekhoff, E. M. W., et al. (2018) · European Journal of Endocrinology · doi:10.1530/eje-18-0006 · Cited by 72 · see citing works
Flushing in (neuro)endocrinology
Hannah-Shmouni, F., Stratakis, C. A., & Koch, C. A. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9394-8 · Cited by 67 · see citing works
Sinus Tachycardia: a Multidisciplinary Expert Focused Review
Mayuga, K. A., Fedorowski, A., Ricci, F., Gopinathannair, R., Dukes, J. W., Gibbons, C., Hanna, P., Sorajja, D., Chung, M., Benditt, D., et al. (2022) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.121.007960 · Cited by 59 · see citing works
Perioperative care of phaeochromocytoma
Connor, D., & Boumphrey, S. (2016) · BJA Education · doi:10.1093/bjaed/mkv033 · Cited by 54 · see citing works
First-line screening tests for Cushing’s syndrome in patients with adrenal incidentaloma: the role of urinary free cortisol measured by LC-MS/MS
Ceccato, F., Antonelli, G., Frigo, A. C., Regazzo, D., Plebani, M., Boscaro, M., & Scaroni, C. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-017-0644-8 · Cited by 44 · see citing works
Daily salivary cortisol and cortisone rhythm in patients with adrenal incidentaloma
Ceccato, F., Barbot, M., Albiger, N., Antonelli, G., Zilio, M., Todeschini, M., Regazzo, D., Plebani, M., Lacognata, C., Iacobone, M., et al. (2018) · Endocrine · doi:10.1007/s12020-017-1421-3 · Cited by 38 · see citing works
Flushing disorders associated with gastrointestinal symptoms: Part 1, neuroendocrine tumors, mast cell disorders and hyperbasophila
Rastogi, V., Singh, D., Mazza, J. J., Parajuli, D., & Yale, S. H. (2018) · Clinical Medicine & Research · doi:10.3121/cmr.2017.1379a · Cited by 32 · see citing works
The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma
Wang, Y., Liu, B., Li, F., Zhang, Y., Gao, X., Wang, Y., & Zhou, H. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1274239 · Cited by 18 · see citing works
An update on adrenal endocrinology: significant discoveries in the last 10 years and where the field is heading in the next decade
Kamilaris, C. D. C., & Stratakis, C. A. (2018) · HORMONES · doi:10.1007/s42000-018-0072-y · Cited by 7 · see citing works

Plasma metanephrines: a novel and cost-effective test for pheochromocytoma
Eisenhofer, G., Walther, M. M., Keiser, H. R., Lenders, J. W. M., Friberg, P., & Pacák, K. (2000) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2000001000005 · Cited by 44 · see citing works
Self-citation
Circulating and Urinary Catecholamines in Pheochromocytoma
Bravo, E. L., Tarazi, R. C., Gifford, R. W., et al. (1979) · New England Journal of Medicine · doi:10.1056/nejm197909273011302 · Cited by 361 · see citing works
Pheochromocytoma
Reda, S. A., Japp, E., Galati, S.-J., Krakoff, L. R., & Levine, A. C. (2022) · Springer eBooks · doi:10.1007/978-3-030-84367-0_19 · Cited by 2 · see citing works
Plasma free metanephrines in the diagnosis of pheochromocytoma: diagnostic accuracy and strategies for Japanese patients
Tanaka, Y., Isobe, K., Ma, E., Imai, T., Kikumori, T., Matsuda, T., Maeda, Y., Sakurai, A., Midorikawa, S., Hataya, Y., et al. (2014) · Endocrine Journal · doi:10.1507/endocrj.ej13-0277 · Cited by 13 · see citing works
A2320 Evaluation of an enzyme immunoassay for plasma-free metanephrines in the localization and qualitative diagnosis of Pheochromocytoma and Paraganglioma
Caini, F., Wang, H., & Zhao, H. (2018) · Journal of Hypertension · doi:10.1097/01.hjh.0000548541.44841.bf · Cited by 1 · see citing works

Authors: Lenders, J. W. M., Duh, Q.-Y., Eisenhofer, G., Gimenez-Roqueplo, A.-P., Grebe, S. K. G., Murad, M. H., Naruse, M., Pacak, K., & Young, W. F.
Affiliations: Radboud University Medical Center (NL)
San Francisco VA Medical Center (US)
University Hospital Dresden (G.E.), 01307 Dresden, Germany;
Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, (A.-P.G.-R.), F-75015 Paris, France;
Mayo Clinic (US)
Kyoto Medical Center (JP)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (K.P.), Bethesda, Maryland 20892;
ORCID: Lenders, Jacques W. M.
Duh, Quan-Yang
Murad, Mohammad Hassan
Naruse, Mitsuhide
Young, William F.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2014-06-01
Volume: 99
Issue: 6
Pages: 1915-1942
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2014-1498
OpenAlex: W2135003179
Cited by: 2,827
References: 267
Citations by year: 2026: 208 · 2025: 251 · 2024: 253 · 2023: 265 · 2022: 299 · 2021: 321 · 2020: 292 · 2019: 250 · 2018: 217 · 2017: 181 · 2016: 140 · 2015: 121 · 2014: 23
FWCI: 153.60
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 907 d)
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion)
Radboud Repository (Radboud University) (submittedVersion)
Funders: European Society of Endocrinology
Society for Endocrinology
Topics: Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
Health Sciences › Medicine › Epidemiology › Neuroendocrine Tumor Research Advances
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Renal cell carcinoma treatment
Keywords: pheochromocytoma, paraganglioma, metanephrine, pre-analytical variables, 123I-MIBG scintigraphy, genetic testing, SDHB mutation, SDHx mutations, adrenalectomy, partial adrenalectomy, metastatic disease, multidisciplinary management, lifelong follow-up
MeSH terms: Adrenal Gland Neoplasms, Adrenalectomy, Combined Modality Therapy, Diagnostic Techniques, Endocrine, Diagnostic Imaging, Endocrinology, Humans, Paraganglioma, Pheochromocytoma, Evidence-Based Medicine, Perioperative Care, Consensus, Precision Medicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks