Cited by 809Angiogenesis and VEGF in CancerLymphatic System and DiseasesMathematical Biology Tumor Growth

The DOI matches its Crossref record; 270 of the 271 references it cites were found in a registry or an index.

Mechanisms of normal and tumor-derived angiogenesis

Papetti, Michael, Herman, Ira M.·2002·American Journal of Physiology-Cell Physiology

DOI 10.1152/ajpcell.00389.2001

Open this paper in CoChat — free account

Abstract

Often those diseases most evasive to therapeutic intervention usurp the human body's own cellular machinery or deregulate normal physiological processes for propagation. Tumor-induced angiogenesis is a pathological condition that results from aberrant deployment of normal angiogenesis, an essential process in which the vascular tree is remodeled by the growth of new capillaries from preexisting vessels. Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients. Within the confines of a tumor, the availability of nutrients is limited by competition among actively proliferating cells, and diffusion of metabolites is impeded by high interstitial pressure (Jain RK. Cancer Res 47: 3039–3051, 1987). As a result, tumor cells induce the formation of a new blood supply from the preexisting vasculature, and this affords tumor cells the ability to survive and propagate in a hostile environment. Because both normal and tumor-induced neovascularization fulfill the essential role of satisfying the metabolic demands of a tissue, the mechanisms by which cancer cells stimulate pathological neovascularization mimic those utilized by normal cells to foster physiological angiogenesis. This review investigates mechanisms of tumor-induced angiogenesis. The strategies used by cancer cells to develop their own blood supply are discussed in relation to those employed by normal cells during physiological angiogenesis. With an understanding of blood vessel growth in both normal and abnormal settings, we are better suited to design effective therapeutics for cancer.

Integrity signals

Registry

Crossref · 10.1152/ajpcell.00389.2001

Cites

270 of 270 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Angiogenesis in cancer and other diseases
Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070
Angiogenesis in cancer, vascular, rheumatoid and other disease
Folkman, J. (1995) · Nature Medicine · doi:10.1038/nm0195-27 · Cited by 7,627
Mechanisms of angiogenesis
Risau, W. (1997) · Nature · doi:10.1038/386671a0 · Cited by 5,727
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
Shweiki, D., Itin, A., Soffer, D., & Keshet, E. (1992) · Nature · doi:10.1038/359843a0 · Cited by 4,617
What Is the Evidence That Tumors Are Angiogenesis Dependent?
Folkman, J. (1990) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/82.1.4 · Cited by 4,509
Endostatin: an endogenous inhibitor of angiogenesis and tumor growth
O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., & Folkman, J. (1997) · Cell · doi:10.1016/s0092-8674(00)81848-6 · Cited by 4,486
Tumors: Wounds That Do Not Heal
Flier, J. S., Underhill, L. H., & Dvorak, H. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612253152606 · Cited by 4,391
Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid
Senger, D. R., Galli, S. J., Dvořàk, A. M., Perruzzi, C. A., Harvey, V. S., & Dvorak, H. F. (1983) · Science · doi:10.1126/science.6823562 · Cited by 3,969
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L., & Schuh, A. C. (1995) · Nature · doi:10.1038/376062a0 · Cited by 3,931
Vascular-specific growth factors and blood vessel formation
Yancopoulos, G. D., Davis, S., Gale, N. W., Rudge, J. S., Wiegand, S. J., & Holash, J. (2000) · Nature · doi:10.1038/35025215 · Cited by 3,699

Flagged first, then by citations

Show all 271 references

1 of the 271 references couldn’t be matched to a known paper.

Research works printed but not linked: 32

Ambs S, 1999, Cancer Res, 59, 5773
Borgstrom P, 1996, Cancer Res, 56, 4032
Clark RA, 1996, Am J Pathol, 148, 1407
Compagni A, 2000, Cancer Res, 60, 7163
Deroanne CF, 1997, Cancer Res, 57, 5590
Dumont DJ, 1992, Oncogene, 7, 1471
Dvorak HF, 1995, Am J Pathol, 146, 1029
Esser S, 1998, J Cell Sci, 110, 2065
Folkman J, 1988, Am J Pathol, 130, 393
Gately S, 1996, Cancer Res, 56, 4887
Goto F, 1993, Lab Invest, 69, 508
Healy AM, 1992, Eur J Cell Biol, 59, 56
Hughes S, 2000, Invest Ophthalmol Vis Sci, 41, 1217
Jain RK., 1987, Cancer Res, 47, 3039
Kitsukawa T, 1995, J Biol Chem, 121, 4309
Kohn S, 1992, Lab Invest, 67, 596
Korhonen J, 1994, Oncogene, 9, 395
Luca M, 1997, Am J Pathol, 151, 1105
Maglione D, 1993, Oncogene, 8, 925
Merwin JR, 1991, Am J Pathol, 138, 37
Millauer B, 1996, Cancer Res, 56, 1615
Nicosia RF, 1994, Am J Pathol, 145, 1023
Pajusola K, 1992, Cancer Res, 52, 5738
Pierce GF, 1992, Am J Pathol, 140, 1375
Senger DR, 1996, Am J Pathol, 149, 293
Senger DR, 1986, Cancer Res, 46, 5629
Takahashi Y, 1995, Cancer Res, 55, 3964
Tanaka T, 1998, Cancer Res, 58, 3362
Todaro GJ, 1990, Semin Cancer Biol, 1, 257
Topp MS, 1995, Cancer Res, 55, 2173
Vlodavsky I, 2000, Isr Med Assoc J, 2, 37
Ziche M, 1982, J Natl Cancer Inst, 69, 475

Sorted by citations

Items 601–700 of 808

Tumor Angiogenesis – factors influencing the development of a tumor vascular network and assessment of neoangiogenesis in histopathological samples
Sobczyńska-Rak, A., SILMANOWICZ, P., & Polkowska, I. (2016) · Medycyna Weterynaryjna · doi:10.21521/mw.5563 · Cited by 3
Immune Response Role of Angiogenesis Inhibitors
Nemunaitis, J. J., Devanaboyina, M., Ngo, N. T., Albalawy, R., Filipiak, L., Staats, H., Stanbery, L., Hamouda, D., & Nemunaitis, J. J. (2021) · Clinical Oncology and Research · doi:10.31487/j.cor.2021.02.01 · Cited by 2
Tumor Angiogenesis and Modulators
Xu, K. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.95139 · Cited by 3
Increased HIF-1alpha And VEGF Expression Found in Various T Stages of Clear Cell Renal Cell Carcinoma
Octavianda, Y., & Rahaju, A. S. (2018) · Folia Medica Indonesiana · doi:10.20473/fmi.v54i2.8858 · Cited by 3
Recent Advances in the Study of Chemical Constituents and Pharmacological Activities of Centipeda minima
赵, 荣. (2021) · Pharmacy Information · doi:10.12677/pi.2021.101004 · Cited by 3
GT198 Is a Target of Oncology Drugs and Anticancer Herbs
Pang, J., Gao, J., Zhang, L., Mivechi, N. F., & Ko, L. (2021) · Frontiers in Oral Health · doi:10.3389/froh.2021.679460 · Cited by 3
The Cellular Microenvironment of Head and Neck Squamous Cell Carcinoma
Mathew, M., & Mary, S. (2012) · InTech eBooks · doi:10.5772/25652 · Cited by 3
In Vitro Angiogenesis Assay: Endothelial Migration, Proliferation, and Tube Formation
Hayakawa, K., Liang, A. C., Xing, C., Lo, E. H., & Arai, K. (2015) · Springer eBooks · doi:10.1007/978-94-017-9716-0_1 · Cited by 3
Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging
Bitton, R. R., Zemp, R. J., Yen, J. T., Wang, L. H., & Shung, K. K. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4352754 · Cited by 3
Markers of Angiogenesis Associated with Surgical Attenuation of Congenital Portosystemic Shunts in Dogs
Tivers, M., House, A. K., Smith, K. C., Wheeler-Jones, C. P. D., & Lipscomb, V. J. (2014) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.12411 · Cited by 3
Helicobacter pylori bacteria: Tools for Eradication
Olivier, R. (2009) · Cited by 3
MDA‐MB‐231 and 8701BC breast cancer lines promote the migration and invasiveness of ECV304 cells on 2D and 3D type‐I collagen matrix
Saladino, S., Salamone, M., & Ghersi, G. (2017) · Cell Biology International · doi:10.1002/cbin.10817 · Cited by 3
Imaging of Tumor Metabolism: MR Spectroscopy
Rizwan, A., & Glunde, K. (2013) · Springer eBooks · doi:10.1007/978-3-642-40412-2_8 · Cited by 3
Microvesicles Produced by Natural Killer Cells Regulate the Formation of Blood Vessels
Markova, K. L., Козырева, А. Р., Соколов, Д. И., & Selkov, S. А. (2020) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-020-05017-y · Cited by 3
Angiogenesis in goitrogenesis
Eggo, M. C. (2003) · Current Opinion in Endocrinology & Diabetes · doi:10.1097/00060793-200310000-00007 · Cited by 3
An Overview of Cancer
De, S. K. (2022) · Wiley eBooks · doi:10.1002/9783527838561.ch1 · Cited by 4
Pro‐Angiogenic and Anti‐Angiogenic Effects of Phytochemicals as Nutraceuticals
Kumar, V., Ghosh, S., Saini, S., Agrawal, H., Milind, D. P., Sircar, D., & Roy, P. (2022) · Wiley eBooks · doi:10.1002/9781119746843.ch20 · Cited by 3
A primer on metabolic contributions in tumor angiogenic microenvironment
Ocaña, M. C., Bernal, M., Quesada, A. R., & Medina, M. Á. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189417 · Cited by 4
Deciphering the Angiogenic Switch: The Role of miRNAs in Breast Cancer
El‐Moaty, H. I. A., Doghish, A. S., Aly, S. H., Abd‐Elmawla, M. A., Tabaa, M. M. E., Rizk, N. I., Elesawy, A. E., Mageed, S. S. A., Mohammed, O. A., Elkhawaga, S. Y., et al. (2026) · IUBMB Life · doi:10.1002/iub.70102 · Cited by 2
Current Insights Into Canine Cutaneous Melanocytic Tumours Diagnosis
Resende, L., Moreira, J., Prada, J., QUEIROGA, F. L., & Pires, I. C. R. (2015) · InTech eBooks · doi:10.5772/59480 · Cited by 2
Novel Anti‐Tumor Effect of Natural Products from Aloe vera Resin and their In‐Vitro/In‐Silico Targeting Mechanism of Carbonic Anhydrase‐II and IX
Khan, M., Halim, S. A., Rehman, N. U., Khan, A., Gibbons, S., Csük, R., Uddin, J., & Al‐Harrasi, A. (2024) · Chemistry & Biodiversity · doi:10.1002/cbdv.202401978 · Cited by 2
Comparative safety profile of tyrosine kinase inhibitors in NSCLC: a network meta-analysis of hypertension and thrombotic risks
Tan, M., Pu, C., Wang, Z., & Jin, C. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1491990 · Cited by 2
Therapeutic targeting of protein arginine methyltransferases reduces breast cancer progression by disrupting angiogenic pathways
Maphalala, K., Ramali, D. P., Maebele, L. T., Mulaudzi, T. V., Mabeta, P., Dlamini, Z., & Damane, B. P. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.102172 · Cited by 2
Assessing blood vascular endothelial growth factor level in patients with vulvovaginal atrophy
Сергеевна, Г. О., Khizroeva, J. K., Солопова, А. Г., Ivanov, A. E., Blinov, D. V., & Tatarintseva, А. Y. (2025) · Obstetrics Gynecology and Reproduction · doi:10.17749/2313-7347/ob.gyn.rep.2025.684 · Cited by 2
Therapeutic Implications of Angiogenesis in Cancer
Makhoul, I., Atrash, S., Arnaoutakis, K., Safar, M., Pennisi, A., Huffman, L. B., & Griffin, R. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-61115-0_9 · Cited by 2
Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis
Yılmaz, Y., Güneş, A., Topel, H., & Atabey, N. (2017) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-017-9958-1 · Cited by 2
Electroporation of transplantable tumors for the enhanced accumulation of photosensitizers
Tamošiūnas, M., Labanauskiene, J., Juodkazis, S., Didžiapetrienė, J., & Rotomskis, R. (2004) · Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna · Cited by 2
Effects of Tumor Microenvironment on Hyperthermia, Photodynamic and Nanotherapy
Baronzio, G., Baronzio, A., Crespi, E., & Freitas, I. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9576-4_10 · Cited by 2
Effects of implantation of bone marrow cells on cytokine levels in the ischemic heart tissue. An experimental study
Ünlü, Y., & Karapolat, S. (2008) · Journal of Cardiothoracic Surgery · doi:10.1186/1749-8090-3-30 · Cited by 2
Clinical Development of Sorafenib (BAY 43–9006) VEGFR and RAF Inhibitor
Voliotis, D., & Dumas, J. (2007) · Springer eBooks · doi:10.1007/978-3-540-33177-3_36 · Cited by 2
The Dark Chocolate against Angiogenesis?
Khan, S. U. (2015) · Journal of Cancer Prevention & Current Research · doi:10.15406/jcpcr.2015.02.00050 · Cited by 2
Tumor Vascular Interaction in Melanomas and Neurogenesis: A Review
Iyengar, B. (2014) · Journal of Pigmentary Disorders · doi:10.4172/2376-0427.1000112 · Cited by 2
Assessment of Plasma Endostatin Levels in Patients with Acute Myeloblastic and Lymphoblastic Leukemia
Dağdaş, S. (2011) · International Journal of Hematology and Oncology · doi:10.4999/uhod.10015 · Cited by 2
Screening Functional Foods as Inhibitors of Angiogenesis Biomarkers
Losso, J. N. (2007) · Nutraceutical science and technology · doi:10.1201/9781420015584.ch23 · Cited by 2
Pyran-2-one Derivatives from the Roots of Croton crassifolius
Huang, W., Wang, J., Liang, Y., Li, Y.-L., & Wang, G. (2016) · Natural Product Communications · doi:10.1177/1934578x1601100626 · Cited by 2
Tumour Angiogenesis in Breast Cancer
Singh, P. G., Basalingappa, K. M., Gopenath, T. S., & Sushma, B. V. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.102944 · Cited by 2
Mechanism of Controlling Blood Vessel Growth and Development and Identification of Therapeutics Against Pathological Angiogenesis
Parida, S., & Mandal, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-803963-2.50001-6 · Cited by 2
Effect of THP-1 Cells on the Formation of Vascular Tubes by Endothelial EA.hy926 Cells in the Presence of Placenta Secretory Products
Lvova, T. Y., Belyakova, K. L., Selkov, S. А., & Соколов, Д. И. (2017) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-017-3657-6 · Cited by 2
Crucial Role of Diabetes Mellitus in Delayed Angiogenesis of Wound
Raghav, A. (2018) · Journal of pharmacology & clinical research · doi:10.19080/jpcr.2018.05.555662 · Cited by 2
Selectivity and Toxicity of Oncolytic Antimicrobial Peptides
Phoenix, D. A., Dennison, S. R., & Harris, F. (2013) · Wiley eBooks · doi:10.1002/9783527652853.ch6 · Cited by 2
THE ROLE OF VEGF FAMILY IN ANGIOGENESIS, TUMOR GROWTH AND METASTASIS
Yang, X. (2014) · Figshare · Cited by 2
Hepatic Tumor Growth: Target for Angiogenesis Inhibition?
Sarraf‐Yazdi, S., Mi, J., & Clary, B. M. (2005) · World Journal of Surgery · doi:10.1007/s00268-004-7810-9 · Cited by 2
Principles of Antiangiogenic Therapy
Chau, C. H., & Figg, W. D. (2010) · Springer eBooks · doi:10.1007/978-1-60327-829-4_17 · Cited by 2
Opto-acoustic imaging of relative blood oxygen saturation and total hemoglobin for breast cancer diagnosis
Zalev, J., Richards, L. M., Clingman, B. A., Harris, J., Cantu, E., Menezes, G. L. G., Avila, C., Bertrand, A., Saenz, X., Miller, S., et al. (2022) · doi:10.32920/21290946.v1 · Cited by 2
Mechanisms Involved in Apice Closure of Pulpless Teeth – Literature Review
Neto, A. P. D. S., Maia, S. M. A. S., Leão, J. C., Quidute, I. L., Guimarães, C. D. S., Alves, S., Álvares, P. R., Ribeiro, M. I. G., & Silva, L. B. (2021) · The Open Dentistry Journal · doi:10.2174/1874210602115010127 · Cited by 1
Antiangiogenic DPPA-nanoparticles combined with an immune checkpoint inhibitor for the treatment of unresectable hepatocellular carcinoma
Huang, Z., Tan, J., Tan, S., Yin, L. W., Li, S., Zhang, W., Zhang, F., Liang, Y., Fang, J., Lin, L., et al. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.103114 · Cited by 1
Mast Cells in and Their Cellular Interactions Within the Tumor Environment
Jackson, C. W., Reji, M. A., Pratt, C. M., Nguyen, S. M. T., & Krishnaswamy, G. A. (2025) · Springer eBooks · doi:10.1007/978-3-030-80962-1_21-2 · Cited by 1
Pretreatment arterial spin labeling combined with radiological depth of invasion predicts treatment outcome in nonmetastatic NPC
Yang, F., Peng, W., Wei, H., Li, X., Yu, X., Li, L., Zhao, Y., Xie, L., Lin, M., & Zhang, H. (2025) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2025.110765 · Cited by 1
Ultrasound-mediated targeted micro/nanobubbles: breaking new boundaries in precision tumor therapy
Yang, M., Zhang, Z., Zhou, H., Luo, Z., Wang, Y., Li, S., Liu, Z., & Zhang, X. (2026) · International Journal of Surgery · doi:10.1097/js9.0000000000004796 · Cited by 2
Dual-mechanism of phytochemicals in cancer therapy: synergistic anti-angiogenic potency in cancer and proangiogenic impact against chemotherapy-induced cytotoxicity in vital organs
Abouzed, D. E. E., Bayoumy, N. M. K., Hagar, H., Rabea, S. M., Hashem, H., & Khalifa, H. O. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1783390 · Cited by 1
PEG-β-Cyclodextrin polymer-based formulation to increase the antiangiogenic activity of rutin in vivo
Gaetano, F. D., Dossi, E., Cacciola, A., Totaro, N., Santonocito, D., Pulvirenti, L., Giofrè, S. V., Paladini, G., Pilloni, A., Germanò, M. P., et al. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.126812 · Cited by 1
Tumor Angiogenesis and Lymphangiogenesis: Microenvironmental Soil for Tumor Progression and Metastatic Dissemination
Paupert, J., de Velde, M. V., Kridelka, F., & Noël, A. (2014) · Springer eBooks · doi:10.1007/978-2-8178-0466-8_13 · Cited by 1
Histology of Microvascular Aging of Human Skin
Helmbold, P. (2015) · Springer eBooks · doi:10.1007/978-3-642-27814-3_2-2 · Cited by 1
Dendritic Cells: From Inducers of Specific T-Cell Responses to Promoters of Angiogenesis
Coukos, G., & Benencia, F. (2009) · Springer eBooks · doi:10.1007/978-0-387-88611-4_16 · Cited by 1
A single fusion signal for t(14;18)(q32;q21) translocation is present in both the follicular lymphoma and local endothelial cells
Zhou, X., Li, Q., Wang, Y., Huang, S., Jiang, L., Zhou, J., & Cao, Y. (2012) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-012-0056-0 · Cited by 1
Growth inhibition of breast cancer in rat by AAV mediated angiostatin gene
Li, R., Chen, H., & Ren, C.-S. (2007) · Chinese Journal of Cancer Research · doi:10.1007/s11670-007-0108-3 · Cited by 1
Ex vivoDetermination of an Estradiol Analogue-Induced Changes on Platelet Morphology and Angiogenic Biomarkers
Repsold, L., Pretorius, E., & Joubert, A. M. (2015) · Microscopy and Microanalysis · doi:10.1017/s1431927615015214 · Cited by 1
Development of Novel Anti-Cancer Strategies Based on Angiogenesis Inhibition
Gude, R. P., Patil, P. S., Kamran, M. Z., & Goel, P. N. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-803963-2.50005-3 · Cited by 1
Elucidation Of Structure - Function Relationship In Families Of Copper Binding Proteins In Homo Sapiens – A Bioinformatics Approach
Mathangi Jayaraman Sudarshana, N., Natarajan, V., Vetrivel, U., & Sulochana., K. N. (2012) · International Journal of Pharma and Bio Sciences · Cited by 1
The Value of Antiangiogenics in Breast Cancer Therapy
Banys-Paluchowski, M. J., Fehm, T. N., & Müller, V. (2017) · Springer eBooks · doi:10.1007/978-3-319-31215-6_24-1 · Cited by 1
The Cerebral Microvasculature and Responses to Ischemia
Hamann, G. F., & del Zoppo, G. J. (2004) · Elsevier eBooks · doi:10.1016/b0-44-306600-0/50045-6 · Cited by 1
Literature Review on the Benefits of Thermotherapy to Boost Immune System and Reduce Viral Replication
Grant, G., & Heuvel, J. P. V. (2020) · Acta Scientific Neurology · doi:10.31080/asne.2020.03.0193 · Cited by 1
Contrast‐enhanced ultrasound and pleura imaging: An underestimated pair
Machado, P. (2022) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23103 · Cited by 1
Histology of Microvascular Aging of Human Skin
Helmbold, P. (2009) · Springer eBooks · doi:10.1007/978-3-540-89656-2_2 · Cited by 1
Normal vascular identity (arteries, veins, and lymphatics) and malformations
Gonzalez, L. A., & Dardik, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822546-2.00016-2 · Cited by 1
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity
Kazemi‐Lomedasht, F., Taghizadeh‐Hesary, F., Faal, Z., & Behdani, M. (2024) · Current Protein and Peptide Science · doi:10.2174/0113892037292385240222074908 · Cited by 1
Vestibular schwannoma: structural characteristics, objectification of metabolic dysfunction and its clinical significance (controversial and promising issues)
Malysheva, O. Y., Vaslovych, V. V., Chernenko, O. H., Fedirko, V. O., Shmeleva, A., Skobska, О. Е., & Малышева, Т. А. (2024) · Ukrainian Interventional Neuroradiology and Surgery · doi:10.26683/2786-4855-2024-3(49)-40-58 · Cited by 1
Diabetic Retinopathy and Ocular Melanoma: How Far We Are?
Souto, E. B., Campos, J. R. S., da Ana, R., Fangueiro, J. F., Martins‐Gomes, C., Durazzo, A., Lucarini, M., Sánchez‐López, E., Espina, M., García, M. L., et al. (2020) · Applied Sciences · doi:10.3390/app10082777 · Cited by 1
Cell–biomaterial interactions for blood vessel formation
Kusuma, S., Dickinson, L. E., & Gerecht, S. (2014) · Elsevier eBooks · doi:10.1533/9780857096715.3.350 · Cited by 1
Histology of Microvascular Aging of Human Skin
Helmbold, P. (2016) · Springer eBooks · doi:10.1007/978-3-662-47398-6_2 · Cited by 1
Detection of Possible Symmetries in Vascular Networks by Computer-Assisted Image Analysis
Guidolin, D., Tortorella, C., & Ribatti, D. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2703-7_13 · Cited by 1
Homotypical Regulation of the Functional Activity of Multipotent Mesenchymal Stromal Cells: The Role of Gap Junctions
Ездакова, М. И., Константиновна, М. Д., & Andreeva, E. R. (2023) · Cell and Tissue Biology · doi:10.1134/s1990519x23020049 · Cited by 1
Effect of Monocyte-Like THP-1 Cells on the Formation of Vascular Tubes by EA.Hy926s Endothelial Cells in the Presence of Cytokines
Lvova, T. Y., Игоревна, С. О., Okorokova, L. S., Semenov, V. A., Rebezova, E. A., Selkov, S. А., & Соколов, Д. И. (2015) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-015-2911-z · Cited by 1
Formulations for Local, Magnetically Mediated Hyperthermia Treatment of Solid Tumors
Renard, P. L., Buchegger, F., Petri‐Fink, A., Doelker, É., & Jordan, O. (2012) · Archive ouverte UNIGE (University of Geneva) · Cited by 1
Exploring Means of Exploiting Tumor Pathophysiology
Wootton, T. (2006) · Cited by 1
Therapeutic Angiogenesis and Myocardial Regeneration
Hughes, G. C., & Annex, B. H. (2005) · Humana Press eBooks · doi:10.1385/1-59259-898-6:271 · Cited by 1
Molecular Targets in Gynecologic Cancers
Growdon, W., Foster, R., & Rueda, B. R. (2014) · doi:10.1002/9781118655344.ch1 · Cited by 1
Die Rolle der Rezeptortyrosinkinasen in der Angiogenese
Meyer, S., Hafner, C. M., & VOGT, T. M. (2002) · Der Hautarzt · doi:10.1007/s00105-002-0425-x · Cited by 1
Controlling angiogenesis : Functional studies of angiomotin
Ernkvist, M. (2007) · Figshare · Cited by 1
Foxf2 and Foxc2, two transcription factors that regulate adipocyte metabolism
Westergren, R. (2010) · Gothenburg University Publications Electronic Archive (Gothenburg University) · Cited by 1
Development of a Novel Bioassay Chamber to Optimize Autologous Endothelial Cell Viabiligy and Density on Topological and Topographical Substrates
Rubenstein, D. A. (2007) · SUNY Digital Repository Support (State University of New York System) · Cited by 1
Combination chemo and hyperoxia therapy in breast cancer cells using nanoemulsion delivery systems
Gopani, H. (2011) · doi:10.17760/d20001215 · Cited by 1
Imaging of Angiogenesis
Dobrucki, L. W., & Sinusas, A. J. (2007) · Springer eBooks · doi:10.1007/978-0-387-38295-1_26 · Cited by 1
THE ZEBRAFISH AS A MODEL TO ELUCIDATE HUMAN DISEASES AND DEVELOPMENT
Lee, S. L. C. (2011) · Figshare · Cited by 1
Antiangiogenic Proteins, Peptides, and Amino Acids
Losso, J. N., & Bawadi, H. A. (2005) · Nutraceutical science and technology · doi:10.1201/9781420028836.ch10 · Cited by 1
Functional assessment and development of treatment strategies for brain tumors: Promoting neurorestoration and reducing harm to bystander cells and neuroplasticity
Yang, H. (2007) · Texas ScholarWorks (Texas Digital Library)
4 Angiogenesis, Metastasis, and Epigenetics in Cancer
Plumb Claire, L., & Coomber, B. L. (2005) · Handbook of immunohistochemistry and in situ hybridization of human carcinomas · doi:10.1016/s1874-5784(05)80059-5
The role of Src-homology 2 domain containing tyrosine phosphatase 2 in growth factor dependent endothelial signalling and angiogenesis
Mannell, H. (2007) · doi:10.5282/edoc.7096
Differentiation plasticity of stromal vascular fraction cells towards adipose tissue and endothelial structures
Wosnitza, M., & Pallua, N. (2009) · RWTH Publications (RWTH Aachen)
Tratamento de metástases hepáticas de carcinoma colo-rectal
Martins, R. M. (2009) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Immunotherapy of Angiogenesis with DNA Vaccines
Hung, C., Monie, A., & Wu, T. ‐. (2008) · Springer eBooks · doi:10.1007/978-0-387-71518-6_39
Avaliação da atividade antiangiogênica do peptídeo sintético análogo a lunasina e do inibidor bowman-birk em membrana coriolantóica de gallus domesticus.
Vieira, F. S. (2014) · Americanae (AECID Library)
Estudo da correlação entre a incidência de metástases em tumores carcinóides típicos broncopulmonares e biomarcadores teciduais, variáveis clínicas e índice de risco
Pereira, J. C. D. N. (2004) · doi:10.11606/t.5.2004.tde-30102006-160335
ROLE D'ENDOCAN DANS LA CROISSANCE TUMORALE ET EFFETS DES ANTICORPS ANTI-ENDOCAN SUR LE DEVELOPPEMENT TUMORAL
Grigoriu, B.-D., & Lassalle, P. (2006) · OpenGrey (Institut de l'Information Scientifique et Technique)
Linking Endothelial Cell Stimulation to Tumor Growth and Vascular Density: The VEGF – Bcl-2 – CXCL8 Pathway
Jain, H. V., & Jackson, T. L. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0052-3_3
Predição do risco individual de metástase linfática e hematogênica em função da intensidade da linfangiogênese no tumor carcinóide típico broncopulmonar
Laloni, M. T. (2008) · doi:10.11606/t.5.2008.tde-14102008-154346
Rol de la proteína SPARC en los mecanismos de angiogénesis
Colussi, S., & Enrique, E. (2010)
Efeito de campos elétricos exógenos em células tumorais - utilização em quimioterapia de células melanocíticas B16F10.
Andrette, R. (2012) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.87.2012.tde-06062012-114304
Efeitos da terapia com laser baixa potência em melanoma: ensaios in vitro
Santos, A. J. D. S. (2012) · doi:10.11606/d.85.2012.tde-31052013-101630
Caracterização dos efeitos do Amblyomin-X sobre a angiogênese e a célula endotelial
Dias, R. Y. S. (2013) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.9.2013.tde-06092013-152354

Authors: Papetti, M., & Herman, I. M.
Affiliations: Tufts University (US)
ORCID: Herman, Ira M.
Venue: American Journal of Physiology-Cell Physiology
Publisher: American Physiological Society
Published: 2002-05-01
Volume: 282
Issue: 5
Pages: C947-C970
ISSN: 0363-6143 (ISSN-L)
1522-1563
DOI: 10.1152/ajpcell.00389.2001
OpenAlex: W2050499474
Cited by: 809
References: 271
Citations by year: 2026: 11 · 2025: 15 · 2024: 19 · 2023: 33 · 2022: 38 · 2021: 32 · 2020: 36 · 2019: 28 · 2018: 20 · 2017: 41 · 2016: 36 · 2015: 45 · 2014: 42 · 2013: 46 · 2012: 41
FWCI: 2.10
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Physiology-Cell Physiology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01gm055110-04)
National Eye Institute (R01EY009033, EY09033)
National Institute of General Medical Sciences (GM55110)
National Institute of Diabetes and Digestive and Kidney Diseases (P30DK034928)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
Health Sciences › Medicine › Oncology › Lymphatic System and Diseases
Physical Sciences › Mathematics › Modeling and Simulation › Mathematical Biology Tumor Growth
Keywords: tumor angiogenesis, physiological angiogenesis, tumor blood supply, vascular remodeling, capillary proliferation, interstitial fluid pressure, tumor microenvironment, cancer metabolism
MeSH terms: Blood Vessels, Growth Substances, Humans, Models, Cardiovascular, Neoplasms, Neovascularization, Pathologic, Proteins, Receptors, Cell Surface, Neovascularization, Physiologic, Receptor Protein-Tyrosine Kinases, Angiopoietin-2, Receptors, TIE

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Mechanisms of normal and tumor-derived angiogenesis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks