The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Cell mechanics and mechanotransduction: pathways, probes, and physiology
Abstract
Cells face not only a complex biochemical environment but also a diverse biomechanical environment. How cells respond to variations in mechanical forces is critical in homeostasis and many diseases. The mechanisms by which mechanical forces lead to eventual biochemical and molecular responses remain undefined, and unraveling this mystery will undoubtedly provide new insight into strengthening bone, growing cartilage, improving cardiac contractility, and constructing tissues for artificial organs. In this article we review the physical bases underlying the mechanotransduction process, techniques used to apply controlled mechanical stresses on living cells and tissues to probe mechanotransduction, and some of the important lessons that we are learning from mechanical stimulation of cells with precisely controlled forces.
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Cited by
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Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.010 · Cited by 3,941
Alcoholic liver disease: mechanisms of injury and targeted treatment
Louvet, A., & Mathurin, P. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.35 · Cited by 855
Polymer Mechanochemistry: From Destructive to Productive
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Biomechanics approaches to studying human diseases
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Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism
Malone, A. M. D., Anderson, C. T., Tummala, P., Kwon, R. Y., Johnston, T. R., Stearns, T., & Jacobs, C. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700636104 · Cited by 477
Metadata
- Authors
- Huang, H., Kamm, R. D., & Lee, R. T.
- Venue
- American Journal of Physiology-Cell Physiology
- Publisher
- American Physiological Society
- Published
- 2004-07
- Volume
- 287
- Issue
- 1
- Pages
- C1-C11
- ISSN
- 0363-6143 (ISSN-L)
- 1522-1563
- OpenAlex
- W2081892717
- Cited by
- 548
- References
- 94
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- Huang, H., Kamm, R. D., & Lee, R. T. (2004). Cell mechanics and mechanotransduction: pathways, probes, and physiology. American Journal of Physiology-Cell Physiology. https://doi.org/10.1152/ajpcell.00559.2003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
