The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse
Abstract
Conjugated linoleic acid (CLA) is a naturally occurring group of dienoic derivatives of linoleic acid found in the fat of beef and other ruminants. CLA is reported to have effects on both tumor development and body fat in animal models. To further characterize the metabolic effects of CLA, male AKR/J mice were fed a high-fat (45 kcal%) or low-fat (15 kcal%) diet with or without CLA (2.46 mg/kcal; 1.2 and 1.0% by weight in high- and low-fat diets, respectively) for 6 wk. CLA significantly reduced energy intake, growth rate, adipose depot weight, and carcass lipid and protein content independent of diet composition. Overall, the reduction of adipose depot weight ranged from 43 to 88%, with the retroperitoneal depot most sensitive to CLA. CLA significantly increased metabolic rate and decreased the nighttime respiratory quotient. These findings demonstrate that CLA reduces body fat by several mechanisms, including a reduced energy intake, increased metabolic rate, and a shift in the nocturnal fuel mix.
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Chin, S. F., Liu, W., Storkson, J. M., Ha, Y. L., & Pariza, M. W. (1992) · Journal of Food Composition and Analysis · doi:10.1016/0889-1575(92)90037-k · Cited by 1,197
Effect of conjugated linoleic acid on body composition in mice
Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., & Pariza, M. W. (1997) · Lipids · doi:10.1007/s11745-997-0109-x · Cited by 1,163
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Park, Y., Storkson, J. M., Albright, K. J., Liu, W., & Pariza, M. W. (1999) · Lipids · doi:10.1007/s11745-999-0358-8 · Cited by 815
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Metadata
- Authors
- West, D. B., Delany, J. P., Camet, P. M., Blohm, F., Truett, A. A., & Scimeca, J.
- Venue
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Publisher
- American Physiological Society
- Published
- 1998-09-01
- Volume
- 275
- Issue
- 3
- Pages
- R667-R672
- ISSN
- 0363-6119 (ISSN-L)
- 1522-1490
- OpenAlex
- W1930140290
- Cited by
- 466
- References
- 2
- FWCI
- 24.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- West, D. B., Delany, J. P., Camet, P. M., Blohm, F., Truett, A. A., & Scimeca, J. (1998). Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. https://doi.org/10.1152/ajpregu.1998.275.3.r667
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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