Response to exercise after blood loss and reinfusion

Ekblom, B; Goldbarg, A N; Gullbring, B

doi:10.1152/jappl.1972.33.2.175

Cited by 346Cardiovascular and exercise physiologyBlood transfusion and managementTrauma, Hemostasis, Coagulopathy, Resuscitation

Response to exercise after blood loss and reinfusion

Ekblom, B, Goldbarg, A N, Gullbring, B·1972·Journal of Applied Physiology

DOI 10.1152/jappl.1972.33.2.175

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Ekblom et al. demonstrated strong linear relationships between changes in hemoglobin and aerobic capacity.
“The experiments of Ekblom et al. (124) in 1972 (Fig. 4) demonstrated strong linear relationships between changes in hemoglobin [due to withdrawal or retransfusion of 1, 2 or 3 U (400 mL) of blood] and aerobic capacity, established by repeated testing of maximal exercise-induced oxygen consumption before and after each procedure (124).”
From Circulating Testosterone as the Hormonal Basis of Sex Differences in Athletic Performance (2018) · cites this paper as [124]
An 11% increase in circulating hemoglobin translates to a 10% difference in maximal oxygen transfer, which may account for virtually all the 12% sex difference in male and female circulating hemoglobin.
“An 11% increase in circulating hemoglobin translates to a 10% difference in maximal oxygen transfer (124), which may account for virtually all the 12% sex difference in male and female circulating hemoglobin (125).”
From Circulating Testosterone as the Hormonal Basis of Sex Differences in Athletic Performance (2018) · cites this paper as [124]

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“…athletes (and also in normal humans), aerobic power and time trial performance correlate well with the individuals’ normal haemoglobin mass (Figure 2C and E), but not with Htc (Figure 2D and F), whereas increases in either value will increase performance (Ekblom et al., 1972; 1976) (Figure 1).”
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Authors: Ekblom, B., Goldbarg, A. N., & Gullbring, B.
ORCID: Ekblom, B
Venue: Journal of Applied Physiology
Publisher: American Physiological Society
Published: 1972-08
Volume: 33
Issue: 2
Pages: 175-180
ISSN: 0161-7567 (ISSN-L)
8750-7587
1522-1601
DOI: 10.1152/jappl.1972.33.2.175
OpenAlex: W2144408971
Cited by: 346
References: 0
Citations by year: 2026: 5 · 2025: 3 · 2024: 23 · 2023: 10 · 2022: 9 · 2021: 10 · 2020: 9 · 2019: 6 · 2018: 4 · 2017: 6 · 2016: 10 · 2015: 10 · 2014: 8 · 2013: 8 · 2012: 10
FWCI: 6.61
Type: journal article
Language: en
Open access: closed
Locations: Journal of Applied Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Health Sciences › Medicine › Biochemistry › Blood transfusion and management
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Trauma, Hemostasis, Coagulopathy, Resuscitation
Keywords: exercise response, blood loss, blood reinfusion, blood transfusion, exercise physiology
MeSH terms: Adult, Blood Transfusion, Physical Exertion, Heart Rate, Hemoglobins, Humans, Lactates, Male, Motor Activity, Oxygen Consumption, Respiration, Spirometry, Time Factors

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