The DOI matches its Crossref record.
A hemodynamic comparison of young and older endurance athletes during exercise
Abstract
This study assessed the hemodynamic responses to exercise of master athletes (56 +/- 5 yr of age) who placed in the top 10% of their age groups in local 10-km competitive events, competitive young runners (26 +/- 3 yr), young runners matched in training and performance to the master athletes (25 +/- 3 yr), and healthy older sedentary subjects (58 +/- 5 yr). The maximal O2 consumption (VO2max) of the master athletes was 9 and 19% lower than that of the matched young and competitive young runners, respectively. When compared at the same relative submaximal work rates, these three groups had similar stroke volumes and arteriovenous O2 (aVO2) differences, though the master athletes had lower VO2, cardiac output, and heart rate, and higher vascular resistance. The older sedentary group had a lower stroke volume, aVO2 difference, and higher vascular resistance than the master athletes. Maximal stroke volume and estimated aVO2 difference were the same in the three groups of athletes; the lower maximal heart rate of the master athletes appears to account for their lower VO2max. The older sedentary subjects' VO2max was 47% lower than that of the master athletes; this difference was almost equally the result of a lower stroke volume and a lower a-VO2 difference. Thus these older athletes did not exhibit the decline in maximum stroke volume and aVO2 difference that occurs with aging in sedentary individuals; they also appear to have retained a greater peripheral vasodilatory response than their sedentary peers.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It appears that stroke volume and oxygen extraction can be maintained by exercise training during aging.140, 146”
From Hormonal and Metabolic Changes of Aging and the Influence of Lifestyle Modifications (2021) · cites this paper as [146]
Citations
Cited by
Sorted by citations
Items 101–155 of 155
Holloszy, J. O., & Kohrt, W. M. (1995) · Comprehensive physiology · doi:10.1002/cphy.cp110124 · Cited by 14
Self-citationThe historical context and scientific legacy of John O. Holloszy
Hagberg, J. M., Coyle, E. F., Baldwin, K. M., Cartee, G. D., Fontana, L., Joyner, M. J., Kirwan, J. P., Seals, D. R., & Weiss, E. P. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00669.2018 · Cited by 11
Self-citationRequired muscle mass for preventing lifestyle-related diseases in Japanese women
Miyatani, M., Kawano, H., Masani, K., Gando, Y., Yamamoto, K., Tanimoto, M., Oh, T., Usui, C., Sanada, K., Higuchi, M., et al. (2008) · BMC Public Health · doi:10.1186/1471-2458-8-291 · Cited by 12
“It has been suggested that the age-related decline in Vo2max is a consequence of attenuation of central and peripheral functions such as stroke volume, heart rate max (HRmax), peripheral O2 extraction, and lean body mass (LBM) or muscle mass [19,21-25].”
BackgroundMethodStroke volume response to cycle ergometry in trained and untrained older men
McLaren, P., Nurhayati, Y., & Boutcher, S. H. (1997) · European Journal of Applied Physiology · doi:10.1007/s004210050201 · Cited by 12
“Endurance-trained older men have signi®cantly greater aerobic power or maximum oxygen consumption ( _V O2max) compared to that of untrained age-matched men (Hagberg and Holloszy 1985; Heath et al. 1981; Pollock and Schmidt (1987).”
BackgroundSex Differences in the Speed–Duration Relationship of Elite Runners across the Lifespan
Fulton, T. J., Sundberg, C. W., Arney, B. E., & Hunter, S. K. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003112 · Cited by 10
“CS was different between age groups in both men (H [5] = 57.”
BackgroundInfluentialInfluence of age and physical training on measures of cardiorespiratory and muscle endurance
Knapik, J. J., Banderet, L. E., Vogel, J. A., et al. (1996) · European Journal of Applied Physiology · doi:10.1007/bf00242280 · Cited by 10
Chodzko-Zajko, W. J. (1996) · Quest · doi:10.1080/00336297.1996.10484200 · Cited by 10
Skeletal muscle mitochondria: the aerobic gate?
Lindstedt, S. L., & Wells, D. J. (1988) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-5481-9_17 · Cited by 9
Lloyd, A. B., Fiala, D., Heyde, C., & Havenith, G. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00619.2021 · Cited by 9
Effect of age on 16.1-km time-trial performance
Balmer, J., Bird, S. R., Davison, R. R., & Lucía, A. (2007) · Journal of Sports Sciences · doi:10.1080/02640410701446901 · Cited by 11
“This finding has been confirmed by cross-sectional studies that reported significantly higher maximal values of the ventilatory equivalent of oxygen ( _ V Emax: _ V O2max) in veteran competitors (Fuchi, Iwaoka, Higuchi, & Kobayashi, 1989; Hagberg et al., 1985; Hagberg, Yerg, & Seals, 1988; Heath, Hagberg, Ehsani, & Ho…”
ResultHahn, H., Vincent, K. R., Herman, D. C., Chen, C., Zdziarski, L. A., Morgan, C., & Vincent, H. K. (2017) · Research in Sports Medicine · doi:10.1080/15438627.2017.1282359 · Cited by 8
“Separate studies have been conducted to compare metabolic and cardiovascular responses in younger and masters runners at a variety of speeds (preferred, set speeds or speeds based on ventilatory threshold values) (Dias Pantoja, Morin, Peyré-Tartaruga, & Brisswalter, 2016; Hagberg et al., 1985; Peiffer, Abbiss, Sultana…”
BackgroundAptitude physique aérobie et vieillissement
Prefaut, C., & Massé-Biron, J. (1989) · Science & Sports · doi:10.1016/s0765-1597(89)80054-1 · Cited by 7
Autonomic central coupling during daytime sleep differs between older and younger people
Chen, P., Simon, K. C. N. S., Sattari, N. S., Whitehurst, L. N., & Mednick, S. C. (2022) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2022.107646 · Cited by 10
“Possible influential factors include reduced SA node cell functionality, which results in greater time between heart beats; lower maximal aerobic exercise capacity caused by reduced physiological functioning; and reduced α and β adrenergic receptor sensitivity in the heart as a result of increased sympathetic activity…”
Beltrame, T., Karsten, M., Chacon‐Mikahil, M. P. T., Madruga, V. A., da Silva, E., Borghi‐Silva, A., Gallo, L., & Catai, A. M. (2012) · Revista Brasileira de Medicina do Esporte · doi:10.1590/s1517-86922012000500003 · Cited by 6
Age, muscle fatigue, and walking endurance in pre-menopausal women
Hunter, G. R., Bickel, C. S., Corral, P. D., Byrne, N. M., Hills, A. P., Larson‐Meyer, D. E., Bamman, M. M., & Newcomer, B. R. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1694-1 · Cited by 7
“…women are consistent with previous studies of older adults which showed that age is related to decreased walking endurance (Hunter et al. 2002; Hagberg et al. 1985; Makrides et al. Table 1 Means and standard deviations for all study variables African American European American P Age (years)…”
Saku, K., Tohyama, T., Shinoda, M., et al. (2017) · Physiological Reports · doi:10.14814/phy2.13406 · Cited by 6
“In addition, the peripheral vascular resistance is reduced in exercise (Hagberg et al. 1985).”
BackgroundRenlund, D. G., & Gerstenblith, G. (1987) · Cardiology Clinics · doi:10.1016/s0733-8651(18)30555-1 · Cited by 5
Deobil, S. J. (1989) · American Journal of Health Promotion · doi:10.4278/0890-1171-4.2.85 · Cited by 5
Physical Exercise in the Elderly
Goldberg, A. P., & Hagberg, J. M. (1990) · Elsevier eBooks · doi:10.1016/b978-0-12-627871-2.50024-2 · Cited by 5
Self-citationActive Control of Hypertension
Bove, A. A., SHERMAN, C., & DiNubile, N. A. (1998) · The Physician and Sportsmedicine · doi:10.3810/psm.1998.04.855 · Cited by 4
BENEFITS OF AEROBIC EXERCISE TRAINING WITH RECOMMENDATIONS FOR HEALTHY AGING
Lazzer, S., Rejc, E., & del Torto, A. (2018) · Annales Kinesiologiae · doi:10.35469/ak.2017.135 · Cited by 3
“However, a reduction in stroke volume during maximal exercise in older adults also contributes to the decline in cardiac output (Hagberg et al., 1985).”
BackgroundHaynes, G. R. (2017) · Springer eBooks · doi:10.1007/978-3-319-66878-9_16 · Cited by 3
Brochhagen, J., Barroso, M. T. C., Baumgart, C., Wasmus, D. T., Freiwald, J., & Hoppe, M. (2023) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2023.1218948 · Cited by 2
“Prior studies on endurance capacity revealed that trained adults possessed higher values in central (23, 25) but similar values in peripheral factors (23, 25, 28) compared to sedentary adults.”
BackgroundMethodResultInfluentialLepers, R., Mater, A., Assadi, H., Zanou, N., Grémeaux, V., & Place, N. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1508642 · Cited by 2
“HRmax −1 by 8.8% for cycling and 14.3% for running suggests that maximal stroke volume and/or arteriovenous O 2 difference decreased (Hagberg et al., 1985).”
InfluentialCapelli, C., Ferretti, G., di Prampero, P. E., & Tam, E. (2025) · European Journal of Applied Physiology · doi:10.1007/s00421-025-06031-6 · Cited by 2
Exercise as a Countermeasure for Sarcopenia
Rivas, D. A., & Fielding, R. A. (2010) · Springer eBooks · doi:10.1007/978-90-481-9713-2_15 · Cited by 2
Haynes, G. R. (2008) · Springer eBooks · doi:10.1007/978-0-387-72527-7_17 · Cited by 2
Running performance and physiological characteristics of one man over a twenty-year period.
Bale, P. (1988) · British Journal of Sports Medicine · doi:10.1136/bjsm.22.1.39 · Cited by 2
“Hagberg and co-workers in their study of young and older endurance runners, found that maximum oxygen pulse, maximum stroke volume and maximum arteriovenous difference for oxygen in both groups of runners were similar (Hagberg et al, 1985).”
ResultJackson, A. S., Beard, E. F., Wier, L. T., et al. (1992) · Proceedings of the Human Factors and Ergonomics Society Annual Meeting · doi:10.1177/154193129203600207 · Cited by 2
Seismocardiography: Interpretation and Clinical Application
Sørensen, K. (2021) · doi:10.54337/aau451017905 · Cited by 1
“reports that peak difference in arterial and venous oxygen concentration is not much different when comparing nonathletes to elite athletes [113, 114].”
ResultMAXIMAL OXYGEN UPTAKE AND LACTATE THRESHOLD IN MIDDLE-AGED AND OLDER RUNNERS
Takeshima, N., Kobayashi, F., Tanaka, K., Niihata, S., Watanabe, T., Sumi, K., Suzuki, M., KOMURA, T., MIYAHARA, M., Ueda, K., et al. (1989) · 体力科學 · doi:10.7600/jspfsm1949.38.197 · Cited by 1
The Effects of Endurance and Resistance Training on Blood Pressure
Hirth, V. A., & Schwartz, R. S. (1994) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/s1047-9651(18)30527-8 · Cited by 1
Hood, E. A., Chui, K. K., & Lusardi, M. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-60913-5.00002-7 · Cited by 1
Six-year follow-up of a world record-breaking master marathon runner
Romberger, N. T., Stock, J. M., McMillan, R. K., Overstreet, M. L., Lepers, R., Joyner, M. J., & Farquhar, W. B. (2024) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00474.2024 · Cited by 1
Daussin, F., Dufour, S. P., & Richard, R. (2008) · European Journal of Applied Physiology · doi:10.1007/s00421-008-0778-7 · Cited by 1
“on the question, it appears that some studies measured higher values of _ Qmax for similar _ VO2 max and then lower Da vO2 max compared to our study (Hagberg et al. 1985; McGuire et al. 2001).”
ResultCardiovascular Response to Exercise in Vertebrates: A ReviewPreprint
López-Román, A., Jiménez-Herranz, E., Calderón‐Montero, F. J., Ramos-Álvarez, J. J., & Lucas, R. G. (2023) · Preprints.org · doi:10.20944/preprints202307.0500.v1
Cardiovascular Response to Exercise in Vertebrates: UpdatePreprint
López-Román, A., Lucas, R. G., Jiménez-Herranz, E., Calderón‐Montero, F. J., & Ramos-Álvarez, J. J. (2024) · Preprints.org · doi:10.20944/preprints202307.0500.v2
CHARACTERIZING THE ACUTE MITOCHONDRIAL RESPONSE TO RESISTANCE EXERCISE IN AGING
Ogborn, D. I. (2013) · MacSphere (McMaster University) · doi:10.71548/15322 · Cited by 1
Daussin, F. (2007) · OpenGrey (Institut de l'Information Scientifique et Technique)
Physical Activity and Hypertension: An Overview
Rontoyannis, G. P. (2005) · KARGER eBooks · doi:10.1159/000088225
Aging obviates sex‐specific physiological responses to exercise
Deschenes, M. R., Taylor, J. L., & Mangis, K. A. (2013) · American Journal of Human Biology · doi:10.1002/ajhb.22354
“…studies investigating sex-related differences in physiological responses among the aged focus on a single physiological system, rather than assuming a whole body, or “global,” perspective (Gonzales et al., 2011; Hagberg et al., 1985; Martin et al., 1991; Ogawa et al., 1992; Parker et al., 2010).”
BackgroundFabre, C., Chamari, K., Anselme-Poujol, F., & Prefaut, C. (1994) · Science & Sports · doi:10.1016/s0765-1597(05)80066-8
Errors in facts and logic: what else?
Daussin, F., Dufour, S. P., & Richard, R. (2008) · European Journal of Applied Physiology · doi:10.1007/s00421-008-0906-4
The Role of Exercise Central Hemodynamics for the Clinical Classification of Heart Failure Patients
Iterson, E. H. V. (2015) · University of Minnesota Digital Conservancy (University of Minnesota)
RUNNINGPERFORMANCEAND PHYSIOLOGICALCHARACTERISTICSOFONE MAN OVER A TWENTY-YEARPERIOD
Polytechnic, B. (1988)
Viktigheten av fysisk aktivitet og trening blant eldre
Lohne‐Seiler, H., & Torstveit, M. K. (2012) · Norsk Epidemiologi · doi:10.5324/nje.v22i2.1562
Physiological Changes Affecting Performance of Masters Athletes
Dascombe, B. J., Elsworthy, N., Scott, B. R., Sculley, D., & Reaburn, P. R. J. (2014) · CRC Press eBooks · doi:10.1201/b17541-3
Vascular function, physical performance and aging
Dobrosielski, D. A. (2007) · Louisiana State University · doi:10.31390/gradschool_dissertations.3318
“Given that reduced cardiac outputs during maximal exercise are often observed in older adults [159, 160] it is to be expected that limb blood flow during peak cycling exercise would also decline with age [161-163].”
BackgroundChui, K. K., & Lusardi, M. M. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1936-9.00002-3
Dvig telesne in bojne pripravljenosti pripadnikov slovenske vojske
Šimunič, B., Pišot, R., Vodičar, J., Grabner, T., Dimec, B., Likavec, J., Kovčan, B., Glavač, A., Pruš, D., Pišot, S., et al. (2025) · doi:10.35469/978-961-7195-66-8
Lakatta, E. G. (1994) · Comprehensive physiology · doi:10.1002/j.2040-4603.1994.tb01689.x
Holloszy, J. O., & Kohrt, W. M. (1994) · Comprehensive physiology · doi:10.1002/j.2040-4603.1994.tb01696.x
“Each symbol in A is an average VO~,,, for groups of men or women of different ages from studies in the literature (14,42,45, 54, 56, 59, 66, 88, 98, 128, 135, 153, 155, 157, 173, 176, 186, 212, 223, 226, 228, 231, 303, 313, 322).”
InfluentialSelf-citationBrentano, M. A. (2004) · Americanae (AECID Library)
Metadata
- Authors
- Hagberg, J. M., Allen, W. K., Seals, D. R., Hurley, B. F., Ehsani, A. A., & Holloszy, J. O.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1985-06-01
- Volume
- 58
- Issue
- 6
- Pages
- 2041-2046
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2147230691
- Cited by
- 158
- References
- 0
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 2 · 2017: 6 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 8 · 2012: 8
- FWCI
- 5.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (AG-03038, AG 00078)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Keywords
- aging, endurance athletes, master athletes, exercise hemodynamics, VO2max, stroke volume, arteriovenous oxygen difference, cardiac output, heart rate, vascular resistance, peripheral vasodilation, sedentary older adults
- MeSH terms
- Adult, Aging, Body Composition, Cardiac Output, Physical Exertion, Heart Rate, Hemodynamics, Humans, Middle Aged, Oxygen Consumption, Physical Endurance, Running, Stroke Volume, Vascular Resistance
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
