The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Dehydration reduces cardiac output and increases systemic and cutaneous vascular resistance during exercise
Abstract
This investigation determined the manner in which the cardiovascular system copes with the dehydration-induced reductions in cardiac output (Q) during prolonged exercise in the heat. On two separate occasions, seven endurance-trained subjects (maximal O2 consumption 4.70 +/- 0.41 l/min) cycled in the heat (35 degrees C) for 2 h, beginning at 62 +/- 2% maximal O2 consumption. During exercise, they randomly received either 0.2 liter of fluid and became dehydrated by 4.9 +/- 0.2% of their body weight [i.e., dehydration trial (DE)] or 3.6 +/- 0.4 liter of fluid and replaced 95% of fluid losses [i.e., euhydration trial (EU)]. During the 10- to 120-min period of EU, Q, mean arterial pressure (MAP), systemic vascular resistance (SVR), cutaneous vascular resistance (CVR), and plasma catecholamines did not change while esophageal temperature stabilized at 38.0 +/- 0.1 degrees C. Conversely, after 120 min of DE, Q and MAP were reduced 18 +/- 3 and 5 +/- 2%, respectively, compared with EU (P < 0.05). This was associated with a significantly higher SVR (17 +/- 6%) and plasma norepinephrine concentration (50 +/- 19%, P < 0.05). In addition, CVR was also significantly higher (126 +/- 16 vs. 102 +/- 6% of 20-min value; P < 0.05) during DE despite a 1.2 +/- 0.1 degrees C greater esophageal temperature (P < 0.05). In conclusion, significant reductions in Q are accompanied by significant increases in SVR and plasma norepinephrine and a slight although significant decline in MAP. The cutaneous circulation participates in this systemic vasoconstriction as indicated by increases in CVR despite significant hyperthermia.
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“Hypovolemia results in a decrease in stroke volume and a compensatory increase in heart rate to maintain a given cardiac output [123–125].”
From Fluid Balance in Team Sport Athletes and the Effect of Hypohydration on Cognitive, Technical, and Physical Performance (2017) · cites this paper as [123]
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“and maintain cardiovascular function. 7,28,29”
From National Athletic Trainers' Association Position Statement: Fluid Replacement for the Physically Active (2017) · cites this paper as [28]
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“Hypohydration leads to increased cardiovascular stress during exercise.”
From National Athletic Trainers' Association Position Statement: Fluid Replacement for the Physically Active (2017) · cites this paper as [28]
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“A potential consequence of hypohydration is a generally linear increase in core temperature during physical activity, with core temperature rising approximately 0.15 8 C to 0.20 8 C for every 1% of body weight lost (due to sweating) during activity. 5,28,64”
From National Athletic Trainers' Association Position Statement: Fluid Replacement for the Physically Active (2017) · cites this paper as [28]
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Citations
Cites
Influence of graded dehydration on hyperthermia and cardiovascular drift during exercise
Montain, S. J., & Coyle, E. F. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.73.4.1340 · Cited by 769
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Sawka, M. N., Leon, L. R., Montain, S. J., & Sonna, L. A. (2011) · Comprehensive Physiology · doi:10.1002/cphy.c100082 · Cited by 470
McDermott, B. P., Anderson, S. A., Armstrong, L. E., Casa, D. J., Cheuvront, S. N., Cooper, L., Kenney, W. L., O'Connor, F. G., & Roberts, W. O. (2017) · Journal of Athletic Training · doi:10.4085/1062-6050-52.9.02 · Cited by 438
Fluid and fuel intake during exercise
Coyle, E. F. (2004) · Journal of Sports Sciences · doi:10.1080/0264041031000140545 · Cited by 423
Self-citationCollins, J., Maughan, R. J., Gleeson, M., Bilsborough, J., Jeukendrup, A., Morton, J. P., Phillips, S. M., Armstrong, L., Burke, L. M., Close, G. L., et al. (2021) · British Journal of Sports Medicine · doi:10.1136/bjsports-2019-101961 · Cited by 303
Nuccio, R. P., Barnes, K. A., Carter, J. M., & Baker, L. B. (2017) · Sports Medicine · doi:10.1007/s40279-017-0738-7 · Cited by 252
ter Steege, R. W. F., & Kolkman, J. J. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04980.x · Cited by 145
Creatine and Glycerol Hyperhydration in Trained Subjects before Exercise in the Heat
Easton, C., Turner, S., & Pitsiladis, Y. P. (2007) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.17.1.70 · Cited by 65
Goulet, E. D. B., Aubertin-Leheudre, M., Plante, G. E., & Dionne, I. J. (2007) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.17.4.391 · Cited by 60
The HEAT-SHIELD project — Perspectives from an inter-sectoral approach to occupational heat stress
Morris, N. B., Piil, J. F., Morabito, M., Messeri, A., Levi, M., Ioannou, L. G., Ciuha, U., Pogačar, T., Kajfež Bogataj, L., Kingma, B., et al. (2021) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2021.03.001 · Cited by 47
Logan-Sprenger, H. M., Heigenhauser, G. J. F., Jones, G. L., & Spriet, L. L. (2013) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.23.3.220 · Cited by 43
Physiological and performance effects of glycerol hyperhydration and rehydration
van Rosendal, S. P., Osborne, M. A., Fassett, R. G., & Coombes, J. S. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2009.00254.x · Cited by 37
Fleming, J., & James, L. J. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0044 · Cited by 36
Beis, L. Y., Polyviou, T., Malkova, D., & Pitsiladis, Y. P. (2011) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-8-24 · Cited by 36
Jardine, W. T., Aisbett, B., Kelly, M. K., Burke, L. M., Ross, M. L., Condo, D., Périard, J. D., & Carr, A. J. (2023) · Sports Medicine · doi:10.1007/s40279-023-01885-2 · Cited by 32
Metadata
- Authors
- Gonzalez-Alonso, J., Mora-Rodriguez, R., Below, P. R., & Coyle, E. F.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1995-11-01
- Volume
- 79
- Issue
- 5
- Pages
- 1487-1496
- ISSN
- 8750-7587
- 1522-1601
- Cited by
- 215
- References
- 1
- Language
- en
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