The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Cell-Cell Communication Beyond Connexins: The Pannexin Channels
Abstract
Direct cell-to-cell communication through specialized intercellular channels is a characteristic feature of virtually all multi-cellular organisms. The remarkable functional conservation of cell-to-cell coupling throughout the animal kingdom, however, is not matched at the molecular level of the structural protein components. Thus protostomes (including nematodes and flies) and deuterostomes (including all vertebrates) utilize two unrelated families of gap-junction genes, innexins and connexins, respectively. The recent discovery that pannexins, a novel group of proteins expressed by several organisms, are able to form intercellular channels has started a quest to understand their evolutionary relationship and functional contribution to cell communication in vivo. There are three pannexin genes in mammals, two of which are co-expressed in the developing and adult brain. Of note, pannexin1 can also form Ca 2+-activated hemichannels that open at physiological extracellular Ca 2+concentrations and exhibit distinct pharmacological properties.
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ATP mediates rapid microglial response to local brain injury in vivo
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Nanotubular Highways for Intercellular Organelle Transport
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A network of fast-spiking cells in the neocortex connected by electrical synapses
Galarreta, M., & Hestrin, S. (1999) · Nature · doi:10.1038/47029 · Cited by 960
ELECTRICAL SYNAPSES IN THE MAMMALIAN BRAIN
Connors, B. W., & Long, M. A. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131128 · Cited by 784
Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro
Draguhn, A., Traub, R. D., Schmitz, D., & Jefferys, J. G. R. (1998) · Nature · doi:10.1038/28184 · Cited by 703
Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons
Tamás, G., Buhl, E. H., Lörincz, A., & Somogyi, P. (2000) · Nature Neuroscience · doi:10.1038/73936 · Cited by 648
Impaired Electrical Signaling Disrupts Gamma Frequency Oscillations in Connexin 36-Deficient Mice
Hormuzdi, S. G., Pais, I., LeBeau, F. E. N., Towers, S. K., Rozov, A., Buhl, E. H., Whittington, M. A., & Monyer, H. (2001) · Neuron · doi:10.1016/s0896-6273(01)00387-7 · Cited by 522
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Cited by
Intercellular Ca2+Waves: Mechanisms and Function
Leybaert, L., & Sanderson, M. J. (2012) · Physiological Reviews · doi:10.1152/physrev.00029.2011 · Cited by 331
Cheung, W. Y., Fritton, J. C., Morgan, S. A., Seref-Ferlengez, Z., Basta-Pljakic, J., Thi, M. M., Suadicani, S. O., Spray, D. C., Majeska, R. J., & Schaffler, M. B. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2740 · Cited by 89
Marcoli, M., Cervetto, C., Paluzzi, P., Guarnieri, S., Alloisio, S., Thellung, S., Nobile, M., & Maura, G. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05322.x · Cited by 70
Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria
Akula, S. K., Chen, A. Y., Neil, J. E., Shao, D. D., Mo, A., Hylton, N. K., DiTroia, S., Ganesh, V. S., Smith, R. S., O’Kane, K., et al. (2023) · JAMA Neurology · doi:10.1001/jamaneurol.2023.2363 · Cited by 37
Metadata
- Authors
- Barbe, M. T., Monyer, H., & Bruzzone, R.
- Venue
- Physiology
- Publisher
- American Physiological Society
- Published
- 2006-04
- Volume
- 21
- Issue
- 2
- Pages
- 103-114
- ISSN
- 0886-1714 (ISSN-L)
- 1548-9213
- 1548-9221
- OpenAlex
- W2119996978
- Cited by
- 270
- References
- 8
- FWCI
- 8.47
- Type
- journal article
- Language
- en
- Open access
- closed
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