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Role of Myokines in Exercise and Metabolism

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FGF21 is an Akt‐regulated myokine

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Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers

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The function of previously unappreciated exerkines secreted by muscle in regulation of neurodegenerative diseases

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Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise

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Treadmill Exercise Enhances Post-Stroke Functional Recovery in Mice via the CX3CL1/CX3CR1 Signaling Pathway

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Myokines as potential mediators of changes in glucose homeostasis and muscle mass after bariatric surgery

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Resistance Exercise Selectively Mobilizes Monocyte Subsets: Role of Polyphenols

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Sulforaphane modulates CX3CL1/CX3CR1 axis and inflammation in palmitic acid-induced cell injury in C2C12 skeletal muscle cells

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Exercise Improves Insulin Sensitivity in the Absence of Changes in Cytokines

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Exercise‐evoked intramuscular neutrophil‐endothelial interactions support muscle performance and GLUT4 translocation: a mouse gnawing model study

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Highlighting the idea of exerkines in the management of cancer patients with cachexia: novel insights and a critical review

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Short-term swimming up-regulates pro-inflammatory mediators and cytokines in gilthead seabream (Sparus aurata)

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Effects of long-term exercise training on adipose tissue expression of fractalkine and MCP-1 in patients with type 2 diabetes and stable coronary artery disease: a substudy of a randomized controlled trial

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Exercise and inactivity as modifiers of β cell function and type 2 diabetes risk

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Effects of CX3CR1 and CXCR2 antagonists on running-dependent intramuscular neutrophil recruitments and myokine upregulation

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Charting the Molecular Terrain of Exercise: Energetics, Exerkines, and the Future of Multiomic Mapping

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Oral Administration of Sodium Nitrate to Metabolic Syndrome Patients Attenuates Mild Inflammatory and Oxidative Responses to Acute Exercise

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Endurance training alleviates MCP-1 and TERRA accumulation at old age in human skeletal muscle

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Regulation of toll-like receptors expression in muscle cells by exercise-induced stress

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Changes in Plasma Bioactive Lipids and Inflammatory Markers during a Half-Marathon in Trained Athletes

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Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery

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Circadian Rhythm, Exercise, and Heart.

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Treadmill Training Effect on the Myokines Content in Skeletal Muscles of Mice With a Metabolic Disorder Model

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Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome

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The Potential of Exerkines in Women’s COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise

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Omics Sciences in Regular Physical Activity

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Fractalkine is a key player in skeletal muscle metabolism and pathophysiology

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Skeletal Muscle

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Unilateral hindlimb ischaemia‐induced systemic inflammation is associated with non‐ischaemic skeletal muscle inflammation

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The effect of acute physical and mental stress on soluble cellular adhesion molecule concentration

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Intramuscular administration of fractalkine modulates mitochondrial properties and promotes fast glycolytic phenotype

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Exercise therapy for knee osteoarthritis pain: how does it work? A study protocol for a randomised controlled trial

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Voluntary exercise does not always suppress lung cancer progression

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Vital Role of Visceral Adipose Tissue in Maintaining Cognitive Functions

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Effects of aquatic versus land-based exercise on irisin and fibroblast growth factor 21 expression and triiodothyronine and free fatty acid levels in elderly women

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Acute Inflammatory Response to Eccentric Exercise in Young and Master Resistance-trained Athletes

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CCL2 Gene Expression and Protein Level Changes Observed in Response to Wingate Anaerobic Test in High-Trained Athletes and Non-Trained Controls

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Myokines and Metabolism

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Metabolomics and proteomics as tools to advance the understanding of exercise responses: The emerging role of gut microbiota in athlete health and performance

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The Myokine Adaptome in Health and Disease: Exercise-Induced Cellular Signaling, Muscle–Organ Crosstalk, and Therapeutic Plasticity

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High-intensity interval training with probiotic supplementation decreases gene expression of NF-κβ and CXCL2 in small intestine of rats with steatosis

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Global multi-omics analysis of exerkines in progressive treadmill-exercised rodentsPreprint

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Therapeutic potential of exerkines in neurodegenerative and mental disorders: a narrative review

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The Influence of Physical Activity on the Level of Chronic Inflammation in Health and in Noninfectious Diseases

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Myokines as a promising marker of metabolic disorders and physical activity

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Obesity, Myokines, and Metabolic Health

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Single Nucleotide Polymorphism in Interleukin-6 and Interleukin-8 Genes of Equines

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Cross-Platform Transcriptomic Analysis of 40 Human and Rodent Skeletal Muscle Exerkines

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Human multi‐tissue transcriptomics identifies galectin‐1 and follistatin‐like 1 as exerkines with distinct transcript‐to‐serum coupling after exercise

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Exercise-evoked immunometabolic niches coordinate context-dependent muscle metabolism

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The Systemic Effects of Exercise on Regulators of Muscle and Bone in Girls and Women

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Acute Sprint Interval Exercise Induces a Greater FGF-21 Response in Comparison to Work-Matched Continuous Exercise

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Myokines and Metabolism

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Histamine and the Exercise Responsome

Ely, M. R. (2020) · Scholars' Bank (University of Oregon) · Cited by 1

Peritoneal signalling improves hippocampal BDNF expression in aged mice

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Cytokines as Orchestrators of Skeletal Muscle Tissue Maintenance and the Inflammation Associated With Acquired Autoimmune and Hereditary Muscle Diseases

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Development in Exercise Science-Performances-Drugs: Atypical Scenario

Venkata, R. K. (2017) · MOJ Sports Medicine · doi:10.15406/mojsm.2017.01.00006

Adaptação mitocondrial induzida pelo exercício físico aeróbio: desvendando novos mecanismos moleculares

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Exercise and adipose tissue GLUT4

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Probing the regulation of cellular lipid metabolism by trans fatty acids and the lipid-sensitive ANGPTL4 protein

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Endurance races effects in non-elite runners by clinical biomarkers and bioimpedance measurements

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MYF6-mediated muscle-bone cross-talk and its effect on bone remodelling

Karam, N. (2020) · eScholarship@McGill (McGill) · doi:10.82308/48637

Myokines, Measurement, and Technical Considerations

Willis, C. R. G., Deane, C. S., & Etheridge, T. (2023) · Neuromethods · doi:10.1007/978-1-0716-3315-1_12

Obesity, Myokines, and Metabolic Health

Malandrino, N., & Ahima, R. S. (2023) · Springer eBooks · doi:10.1007/978-3-319-12125-3_56-1

Regulation of Metabolism and Exercise Functions Associated with Skeletal Muscle and Gut Crosstalk

Aoi, W. (2023) · Nippon Eiyo Shokuryo Gakkaishi · doi:10.4327/jsnfs.76.305

Effects of Extreme Physical and Mental Load on Circulating Exerkines in Professional Athletes

Ligetvári, R. (2024) · Pesci Egyetemi Archivum (University of Pécs) · doi:10.15170/pte.2024.013

Pratiquer des activités physiques ou sportives en minimisant les risques

Sultana, R. (2024) · Kinésithérapie la Revue · doi:10.1016/j.kine.2024.07.002

The influence of physical activity on the level of chronic inflammation in health and in non-infectious diseases

Pahomov, N. V., Kostunina, D. S., & Artemenkov, A. A. (2024) · Human Physiology · doi:10.31857/s0131164624030101 · Cited by 1

Role of Myokines and prospects for their role in Diabetes Mellitus Therapy

Nuriya, K., Farida, M., Sharma, R., Liliya, S., Mkhitaryan, X. E., Chergizova, B., Salikhova, Y., Niyazova, Y., Ryspayeva, G., Evnevich, A., et al. (2024) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2024.00786

Study of Blood Biomarkers in Athletes with Lower Gastrointestinal Symptoms After an Ultra-Trail Race

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Myokine-Mediated Muscle-Kidney Crosstalk

Formenti, P., & Umbrello, M. (2025) · Springer eBooks · doi:10.1007/978-3-032-01024-7_14

Myokines in Response to Exercise: Endocrine Function and Systemic Effects of Muscles

Çolak, H. (2025) · Herkes için Spor ve Rekreasyon Dergisi · doi:10.56639/jsar.1758342

Physical activity and microglial metabolism in neurodegenerative diseases

Andoh, M., & Koyama, R. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27340-7.00013-9

Blood Biochemical Responses to Acute Exercise: Findings from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)Preprint

Robbins, J., Katz, D. H., Many, G. M., Rao, P., Smith, G. R., Tiwari, G., Jin, C. A., Spielmann, G., Montalvo, S., Iyer, G. R., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.02.704798

Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity ConsortiumPreprint

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CXCL2 is a modifiable driver of sarcopenic inflammation attenuated by exercise in older women: Integrated transcriptomic and experimental evidence

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Exercise-Induced Skeletal Muscle Secretory Factors and Macrophage Functional Remodeling: Mechanistic Advances

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Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines

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The search for exercise factors in humans

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Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle

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Exercise-Induced Myokine Response Following 75-km Cycling

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Are the Myokines the Mediators of Physical Activity-Induced Health Benefits?

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