Role of Myokines in Exercise and Metabolism

The anti-inflammatory effect of exercise

Petersen, A. M. W., & Pedersen, B. K. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00164.2004 · Cited by 3,100 · cited 3× · see citing works

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

Kahn, B. B., Alquier, T., Carling, D., & Hardie, D. G. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2004.12.003 · Cited by 2,799 · see citing works

Interleukin-8 as a macrophage-derived mediator of angiogenesis

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Exercise and the immune system: regulation, integration, and adaptation

Pedersen, B. K., & Hoffman-Goetz, L. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.1055 · Cited by 1,710 · see citing works

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

Grabstein, K. H., Eisenman, J. R., Shanebeck, K. D., Rauch, C. T., Srinivasan, S., Fung, V., Beers, C., Richardson, J. S., Schoenborn, M. A., Ahdieh, M., et al. (1994) · Science · doi:10.1126/science.8178155 · Cited by 1,422 · see citing works

Interleukin-6 in Biology and Medicine

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Interleukin-6-deficient mice develop mature-onset obesity

Wallenius, V., Wallenius, K., Ahrén, B., Rudling, M., Carlsten, H., Dickson, S. L., Ohlsson, C., & Jansson, J.-O. (2002) · Nature Medicine · doi:10.1038/nm0102-75 · Cited by 1,213 · see citing works

IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans

Steensberg, A., Fischer, C. P., Keller, C., Møller, K., & Pedersen, B. K. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00074.2003 · Cited by 1,135 · see citing works

Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6

Steensberg, A., van Hall, G., Osada, T., Sacchetti, M., Saltin, B., & Pedersen, B. K. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.00237.x · Cited by 1,095 · see citing works

Pro‐ and anti‐inflammatory cytokine balance in strenuous exercise in humans

Ostrowski, K., Rohde, T., Asp, S., Schjerling, P., & Pedersen, B. K. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.287ad.x · Cited by 1,014 · see citing works

Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

Carey, A. L., Steinberg, G. R., Macaulay, S. L., Thomas, W. G., Holmes, A. G., Ramm, G., Prelovsek, O., Hohnen-Behrens, C., Watt, M. J., James, D. E., et al. (2006) · Diabetes · doi:10.2337/db05-1404 · Cited by 898 · see citing works

Muscle‐derived interleukin‐6: mechanisms for activation and possible biological roles

FEBBRAIO, M. A., & PEDERSEN, B. K. (2002) · The FASEB Journal · doi:10.1096/fj.01-0876rev · Cited by 875 · see citing works

Interleukin-6 in acute exercise and training: what is the biological relevance?

Fischer, C. P. (2026) · PubMed · doi:10.22029/eir.2006.1620 · Cited by 817 · see citing works

Exercise and IL‐6 infusion inhibit endotoxin‐induced TNF‐α production in humans

Starkie, R., Ostrowski, S. R., Jauffred, S., Febbraio, M., & Pedersen, B. K. (2003) · The FASEB Journal · doi:10.1096/fj.02-0670fje · Cited by 790 · see citing works

Treatment of rheumatoid arthritis with humanized anti–interleukin‐6 receptor antibody: A multicenter, double‐blind, placebo‐controlled trial

Nishimoto, N., Yoshizaki, K., Miyasaka, N., Yamamoto, K., Kawai, S., Takeuchi, T., Hashimoto, J., Azuma, J., & Kishimoto, T. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20303 · Cited by 786 · see citing works

Interleukin-6 stimulates lipolysis and fat oxidation in humans

van Hall, G., Steensberg, A., Sacchetti, M., Fischer, C., Keller, C., Schjerling, P., Hiscock, N., Møller, K., Saltin, B., Febbraio, M. A., et al. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021687 · Cited by 767 · see citing works

Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease

Bassuk, S. S., & Manson, J. E. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00160.2005 · Cited by 744 · see citing works

Chemokines in pathology and medicine

Baggiolini, M. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00867.x · Cited by 710 · see citing works

IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.

Tilg, H., Dinarello, C., & Mier, J. (1997) · Immunology today (Amsterdam. Regular ed.) · doi:10.1016/s0167-5699(97)01103-1 · Cited by 687 · see citing works

IL-6 signal transduction and its physiological roles: the signal orchestration model

Kamimura, D., Ishihara, K., & Hirano, T. (2003) · Reviews of Physiology, Biochemistry and Pharmacology · doi:10.1007/s10254-003-0012-2 · Cited by 673 · see citing works

Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running

Ostrowski, K., Rohde, T., Zacho, M., Asp, S., & Pedersen, B. K. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.949bp.x · Cited by 673 · see citing works

Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation

Plomgaard, P., Bouzakri, K., Krogh-Madsen, R., Mittendorfer, B., Zierath, J. R., & Pedersen, B. K. (2005) · Diabetes · doi:10.2337/diabetes.54.10.2939 · Cited by 627 · see citing works

Identification and cloning of a novel IL‐15 binding protein that is structurally related to the alpha chain of the IL‐2 receptor.

Giri, J. G., Kumaki, S., Ahdieh, M., Friend, D. J., Loomis, A., Shanebeck, K. D., DuBose, R. F., Cosman, D. J., Park, L. S., & Anderson, D. M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00035.x · Cited by 623 · see citing works

Muscle‐derived interleukin‐6: possible biological effects

Pedersen, B. K., Steensberg, A., & Schjerling, P. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0329c.xd · Cited by 599 · see citing works

The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity

Addison, C., Daniel, T. O., Burdick, M. D., Liu, H., Ehlert, J. E., Xue, Y., Buechi, L., Walz, A., Richmond, A. J., & Strieter, R. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.9.5269 · Cited by 578 · see citing works

Searching for the exercise factor: is IL-6 a candidate?

Pedersen (2003) · Journal of Muscle Research and Cell Motility · doi:10.1023/a:1026070911202 · Cited by 564 · see citing works

Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial

Choy, E. H. S., Isenberg, D. A., Garrood, T., Farrow, S., Ioannou, Y., Bird, H., Cheung, N., Williams, B., Hazleman, B., Price, R., et al. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10623 · Cited by 526 · see citing works

Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content

Keller, C., Steensberg, A., Pilegaard, H., Osada, T., Saltin, B., Pedersen, B. K., & Neufer, P. D. (2001) · The FASEB Journal · doi:10.1096/fj.01-0507fje · Cited by 514 · see citing works

Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells Are Mediated by CXCR2

Heidemann, J., Ogawa, H., Dwinell, M. B., Rafiee, P., Maaser, C., Gockel, H. R., Otterson, M. F., Ota, D. M., Lügering, N., Domschke, W., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m208231200 · Cited by 478 · see citing works

Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction

Febbraio, M. A., Hiscock, N., Sacchetti, M., Fischer, C. P., & Pedersen, B. K. (2004) · Diabetes · doi:10.2337/diabetes.53.7.1643 · Cited by 455 · see citing works

Interleukin‐6 production in contracting human skeletal muscle is influenced by pre‐exercise muscle glycogen content

Steensberg, A., Febbraio, M. A., Osada, T., Schjerling, P., van Hall, G., Saltin, B., & Pedersen, B. K. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00633.x · Cited by 444 · see citing works

Systemic inflammatory response to exhaustive exercise : Cytokine kinetics

鈴木, 克. (2002) · Medical Entomology and Zoology · Cited by 416 · see citing works

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.

Bamford, R. N., Grant, A. J., Burton, J. D., Peters, C., Kurys, G., Goldman, C. K., Brennan, J., Roessler, E., & Waldmann, T. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.4940 · Cited by 411 · see citing works

IL-6 and TNF-α expression in, and release from, contracting human skeletal muscle

Steensberg, A., Keller, C., Starkie, R. L., Osada, T., Febbraio, M. A., & Pedersen, B. K. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00255.2002 · Cited by 410 · see citing works

Contraction-Induced Myokine Production and Release: Is Skeletal Muscle an Endocrine Organ?

Febbraio, M. A., & Pedersen, B. K. (2005) · Exercise and Sport Sciences Reviews · doi:10.1097/00003677-200507000-00003 · Cited by 402 · see citing works

Regulation of the in vitro antibody response by neuroendocrine hormones

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A trauma‐like elevation of plasma cytokines in humans in response to treadmill running

Ostrowski, K., Hermann, C., Bangash, A., Schjerling, P., Nielsen, J. N., & Pedersen, B. K. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.889ba.x · Cited by 398 · see citing works

Impact of a Competitive Marathon Race on Systemic Cytokine and Neutrophil Responses

Suzuki, K., Nakaji, S., Yamada, M., Liu, Q., Kurakake, S., Okamura, N., Kumae, T., Umeda, T., & Sugawara, K. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000048861.57899.04 · Cited by 366 · see citing works

Physical activity and plasma interleukin-6 in humans - effect of intensity of exercise

Ostrowski, K., Schjerling, P., & Pedersen, B. K. (2000) · European Journal of Applied Physiology · doi:10.1007/s004210000312 · Cited by 355 · see citing works

Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run

Nieman, D. C., Davis, J. M., Henson, D. A., Walberg-Rankin, J., Shute, M., Dumke, C. L., Utter, A. C., Vinci, D. M., Carson, J. A., Brown, A., et al. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01130.2002 · Cited by 353 · see citing works

Cytokine changes after a marathon race

Nieman, D. C., Henson, D. A., SMITH, L. L., Utter, A. C., Vinci, D. M., Davis, J. M., Kaminsky, D. E., & Shute, M. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.1.109 · Cited by 331 · see citing works

Prolactin and Growth Hormone in the Regulation of the Immune System

Gala, R. R. (1991) · Experimental Biology and Medicine · doi:10.3181/00379727-198-43286b · Cited by 318 · see citing works

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise.

Kelly, M., Keller, C., Avilucea, P. R., Keller, P., Luo, Z., Xiang, X., Giralt, M., Hidalgo, J., Saha, A. K., Pedersen, B. K., et al. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.05.188 · Cited by 289 · see citing works

The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor?

Pedersen, B. K., Steensberg, A., Fischer, C. P., Keller, C., Keller, P., Plomgaard, P., Petersen, E. W., & Febbraio, M. A. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2004338 · Cited by 273 · see citing works

Skeletal myocytes are a source of interleukin‐6 mRNA expression and protein release during contraction: evidence of fiber type specificity

Hiscock, N. J., Chan, S. M. H., Bisucci, T., Darby, I. A., & Febbraio, M. A. (2004) · The FASEB Journal · doi:10.1096/fj.03-1259fje · Cited by 273 · see citing works

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

Karni, R., Jove, R., & Levitzki, A. (1999) · Oncogene · doi:10.1038/sj.onc.1202835 · Cited by 242 · see citing works

Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects

Pedersen, B. K., Steensberg, A., Keller, P., Keller, C., Fischer, C., Hiscock, N., van Hall, G., Plomgaard, P., & Febbraio, M. A. (2003) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-002-0981-z · Cited by 228 · see citing works

Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses

Riechman, S. E., Balasekaran, G., Roth, S. M., & Ferrell, R. E. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00491.2004 · Cited by 228 · see citing works

Cytokines and chemokines are both expressed by human myoblasts: possible relevance for the immune pathogenesis of muscle inflammation.

Rossi, M. D. (2000) · International Immunology · doi:10.1093/intimm/12.9.1329 · Cited by 227 · see citing works

Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders

Quinn, L. S., Anderson, B. G., Drivdahl, R. H., Alvarez, B., & Argilés, J. M. (2002) · Experimental Cell Research · doi:10.1006/excr.2002.5624 · Cited by 226 · see citing works

Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: Evidence for a skeletal muscle-to-fat signaling pathway

QUINN, L., STRAITBODEY, L., ANDERSON, B., ARGILES, J., & HAVEL, P. (2005) · Cell Biology International · doi:10.1016/j.cellbi.2005.02.005 · Cited by 199 · see citing works

Influence of vitamin C supplementation on oxidative and immune changes after an ultramarathon

Nieman, D. C., Henson, D. A., McAnulty, S. R., McAnulty, L., Swick, N. S., Utter, A. C., Vinci, D. M., Opiela, S. J., & Morrow, J. D. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00961.2001 · Cited by 198 · see citing works

Cross-talk between skeletal muscle and adipose tissue: A link with obesity?

Argilés, J. M. A., López‐Soriano, J., Almendro, V., Busquets, S., & López-Soriano, F. J. (2004) · Medicinal Research Reviews · doi:10.1002/med.20010 · Cited by 194 · see citing works

Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

Pedersen, B. K., & Febbraio, M. A. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01208.2006 · Cited by 177 · see citing works

Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: A potential role in body weight control

Carbó, N., López-Soriano, J., Costelli, P., Alvarez, B., Busquets, S., Baccino, F. M., Quinn, L. S., López-Soriano, F. J., & Argilés, J. M. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(00)00188-4 · Cited by 174 · see citing works

Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training

Nieman, D. C., Davis, J. M., Brown, V. A., Henson, D. A., Dumke, C. L., Utter, A. C., Vinci, D. M., Downs, M. F., Smith, J., Carson, J. A., et al. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01064.2003 · Cited by 166 · see citing works

Cytokine gene expression in human skeletal muscle during concentric contraction: evidence that IL-8, like IL-6, is influenced by glycogen availability

Chan, S. M. H., Carey, A. L., Watt, M. J., & Febbraio, M. A. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00030.2004 · Cited by 156 · see citing works

Interleukin‐6 production in human subcutaneous abdominal adipose tissue: the effect of exercise

Lyngsø, D., Simonsen, L., & Bülow, J. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.019380 · Cited by 155 · see citing works

The T cell and NK cell immune response to exercise.

Gleeson, M., & BISHOP, N. C. (2005) · PubMed · Cited by 152 · see citing works

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans

Steensberg, A., Fischer, C. P., Sacchetti, M., Keller, C., Osada, T., Schjerling, P., van Hall, G., Febbraio, M. A., & Pedersen, B. K. (2003) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.00631.x · Cited by 152 · see citing works

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans

Steensberg, A., Fischer, C. P., Sacchetti, M., Keller, C., Osada, T., Schjerling, P., van Hall, G., Febbraio, M. A., & Pedersen, B. K. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.032938 · Cited by 152 · see citing works

Chemokines are elevated in plasma after strenuous exercise in humans

Ostrowski, K., Rohde, T., Asp, S., Schjerling, P., & Pedersen, B. K. (2001) · European Journal of Applied Physiology · doi:10.1007/s004210170012 · Cited by 146 · see citing works

Role of the Cytokines in the Neuroendocrine-Immune System Axis

Spangelo, B. L., & Gorospe, W. C. (1995) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1995.1001 · Cited by 129 · see citing works

Interleukins and exercise

Gleeson, M. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.00001.x · Cited by 114 · see citing works

Interleukin-15 increases myosin accretion in human skeletal myogenic cultures

Furmanczyk, P. S., & Quinn, L. S. (2003) · Cell Biology International · doi:10.1016/s1065-6995(03)00172-0 · Cited by 109 · see citing works

Effects of interleukin-15 (IL-15) on adipose tissue mass in rodent obesity models: evidence for direct IL-15 action on adipose tissue

Alvarez, B., Carbó, N., López‐Soriano, J., Drivdahl, R. H., Busquets, S., López-Soriano, F. J., Argilés, J. M. A., & Quinn, L. S. (2002) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(02)00148-4 · Cited by 108 · see citing works

Exercise induces interleukin‐8 receptor (CXCR2) expression in human skeletal muscle

Frydelund‐Larsen, L., Penkowa, M., Akerstrom, T., Zankari, A., Nielsen, S., & Pedersen, B. K. (2007) · Experimental Physiology · doi:10.1113/expphysiol.2006.034769 · Cited by 106 · see citing works

The effect of hypophysectomy upon the involution of the thymus in the rat

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Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF

Fong, P., Argent, B. E., Guggino, W. B., et al. (2003) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00509.2002 · Cited by 86 · see citing works

Interleukins

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Interleukin-15 Stimulates C2 Skeletal Myoblast Differentiation

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Interleukin‐8 and de novo mammalian angiogenesis

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Influence of carbohydrate on cytokine and phagocytic responses to 2 h of rowing

Henson, D. A., Nieman, D. C., Nehlsen‐Cannarella, S. L., Fagoaga, O. R., SHANNON, M., BOLTON, M. R., Davis, J. M., GAFFNEY, C. T., Kelln, W., Austin, M. D., et al. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200008000-00005 · Cited by 63 · see citing works

Interleukins 1-beta, -8, and histamine increases in highly trained, exercising athletes

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Thymic hormone activity and spontaneous autoimmunity in dwarf mice and their littermates.

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The effect of diabetes on endothelin, interleukin-8 and vascular endothelial growth factor-mediated angiogenesis in rats

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Stress and infections.

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Atlizumab

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P025 - TNF-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of AS160 phosphorylation

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Muscles, exercise and obesity: skeletal muscle as a secretory organ

Pedersen, B. K., & Febbraio, M. A. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.49 · Cited by 2,909 · see citing works

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

Pedersen, B. K., & Febbraio, M. A. (2008) · Physiological Reviews · doi:10.1152/physrev.90100.2007 · Cited by 2,388 · see citing works

Muscle–Organ Crosstalk: The Emerging Roles of Myokines

Severinsen, M. C. K., & Pedersen, B. K. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa016 · Cited by 1,226 · see citing works

The role of exercise and PGC1α in inflammation and chronic disease

Handschin, C., & Spiegelman, B. M. (2008) · Nature · doi:10.1038/nature07206 · Cited by 1,083 · see citing works

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

Virtue, S., & Vidal-Puig, A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.12.006 · Cited by 1,013 · see citing works

Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance

Moreno-Navarrete, J. M., Ortega, F., Serrano, M., Guerra, E., Pardo, G., Tinahones, F., Ricart, W., & Fernández-Real, J. M. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2749 · Cited by 788 · see citing works

Exercise is the real polypill.

Fiuza-Luces, C., Garatachea, N., Berger, N. A., & Lucia, A. (2013) · Physiology · doi:10.1152/physiol.00019.2013 · Cited by 791 · see citing works

Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms

Booth, F. W., Roberts, C. K., Thyfault, J. P., Ruegsegger, G. N., & Toedebusch, R. G. (2017) · Physiological Reviews · doi:10.1152/physrev.00019.2016 · Cited by 696 · see citing works

Health Benefits of Exercise

Ruegsegger, G. N., & Booth, F. W. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029694 · Cited by 690 · see citing works

Muscles and their myokines

Pedersen, B. K. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.048074 · Cited by 668 · see citing works

The Role of Inflammation in Age-Related Sarcopenia

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An official European Respiratory Society statement on physical activity in COPD

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FGF21 is an Akt‐regulated myokine

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Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism

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Interleukin 6 as an Energy Allocator in Muscle Tissue

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Oversecretion of interleukin-15 from skeletal muscle reduces adiposity

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Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer

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Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

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IL-7 is expressed and secreted by human skeletal muscle cells

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Irisin is inversely associated with intrahepatic triglyceride contents in obese adults

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Anti-Inflammatory Properties of Irisin, Mediator of Physical Activity, Are Connected with TLR4/MyD88 Signaling Pathway Activation

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Musclin is an activity-stimulated myokine that enhances physical endurance

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Role of Adiposity-Driven Inflammation in Depressive Morbidity

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Identification of human exercise-induced myokines using secretome analysis

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Exercise and regulation of adipokine and myokine production

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Iron and the pathophysiology of diabetes

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The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

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The role of extracellular vesicles in skeletal muscle and systematic adaptation to exercise

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Exercise-Induced Myokines can Explain the Importance of Physical Activity in the Elderly: An Overview

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Cellular and molecular mechanisms of sarcopenia: The S100B perspective

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Myokines, physical activity, insulin resistance and autoimmune diseases

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Chronic exercise decreases cytokine production in healthy rat skeletal muscle

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A comparison of sex-specific immune signatures in Gulf War illness and chronic fatigue syndrome

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Ursolic acid-induced elevation of serum irisin augments muscle strength during resistance training in men

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Acute aerobic exercise leads to increased plasma levels of R- and S-β-aminoisobutyric acid in humans

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Exercise Counters the Age-Related Accumulation of Senescent Cells

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Candidate mechanisms accounting for effects of physical activity on breast carcinogenesis

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Myokines as possible therapeutic targets in cancer cachexia

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Adiponectin and Skeletal Muscle

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Is exercise an effective treatment for NASH? Knowns and unknowns

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The Addition of Beta-hydroxy-beta-methylbutyrate and Isomaltulose to Whey Protein Improves Recovery from Highly Demanding Resistance Exercise

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Beneficial effect of exercise on cognitive function during peripheral arterial disease: potential involvement of myokines and microglial anti-inflammatory phenotype enhancement

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Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

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The effect of resistance training on skeletal muscle inflammatory factors in diabetic rats

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Skeletal muscle is an endocrine organ

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