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Cited by 709

The DOI matches its Crossref record; 585 of the 585 references it cites were found in a registry or an index.

Physiology and Pathophysiology of the Calcium Store in the Endoplasmic Reticulum of Neurons

Verkhratsky, Alexei·2005·Physiological Reviews
DOI 10.1152/physrev.00004.2004
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Abstract

The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present in all types of nerve cells. The ER is an interconnected, internally continuous system of tubules and cisterns, which extends from the nuclear envelope to axons and presynaptic terminals, as well as to dendrites and dendritic spines. Ca 2+release channels and Ca 2+pumps residing in the ER membrane provide for its excitability. Regulated ER Ca 2+release controls many neuronal functions, from plasmalemmal excitability to synaptic plasticity. Enzymatic cascades dependent on the Ca 2+concentration in the ER lumen integrate rapid Ca 2+signaling with long-lasting adaptive responses through modifications in protein synthesis and processing. Disruptions of ER Ca 2+homeostasis are critically involved in various forms of neuropathology.

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Crossref · 10.1152/physrev.00004.2004

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Metadata

Authors
Verkhratsky, A.
Venue
Physiological Reviews
Publisher
American Physiological Society
Published
2005-01
Volume
85
Issue
1
Pages
201-279
ISSN
  • 0031-9333 (ISSN-L)
  • 1522-1210
DOI
10.1152/physrev.00004.2004
OpenAlex
W2122054000
Cited by
709
References
585
FWCI
2.17
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.