Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity

Hammarstedt, Ann, Gogg, Silvia, Hedjazifar, Shahram, Nerstedt, Annika, Smith, Ulf·2018·Physiological Reviews

Cites (336)

Items 201–337 of 337

  1. White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
    Andrea Frontini, Alessandra Vitali, Jessica Perugini, Incoronata Murano, Chiara Romiti, Daniel Ricquier, Mario Guerrieri, Saverio Cinti · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  2. Adipose tissue angiogenesis: Impact on obesity and type-2 diabetes
    Silvia Corvera, Olga Gealekman · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  3. BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis
    Birgit Gustafson, Ann Hammarstedt, Shahram Hedjazifar, Jenny M. Hoffmann, Per‐Arne Svensson, Joseph S. Grimsby, Cristina M. Rondinone, Ulf Smith · 2015 · Diabetes
  4. Angiogenesis and obesity
    Lijnen, H. R. · 2008 · Cardiovascular Research
  5. Subcutaneous adipocyte size and body fat distribution
    Yourka D. Tchoukalova, Christina Koutsari, Maksym V. Karpyak, Susanne B. Votruba, Eliana Wendland, Michael D. Jensen · 2008 · American Journal of Clinical Nutrition
  6. Adipocyte size predicts incidence of type 2 diabetes in women
    Malin Lönn, Kirsten Mehlig, Calle Bengtsson, Lauren Lissner · 2009 · The FASEB Journal
  7. Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
    Stefania Maria Filomena Mitola, Cosetta Ravelli, Emanuela Moroni, Valentina Salvi, Daria Leali, Kurt Ballmer‐Hofer, Luca Arrigo Zammataro, Marco Presta · 2010 · Blood
  8. The Small Molecule Harmine Is an Antidiabetic Cell-Type-Specific Regulator of PPARγ Expression
    Hironori Waki, Kye Won Park, Nico Mitro, Liming Pei, Robert D. Damoiseaux, Damien C. Wilpitz, Karen Reue, Enrique Sáez, Peter Tontonoz · 2007 · Cell Metabolism
  9. Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance
    Elisa Álvarez Hernández, SABINE KAHL, Anett Seelig, Paul Begovatz, Martin Irmler, Yuliya Kupriyanova, Bettina Nowotny, P. Nowotny, Christian Herder, Cristina Barosa et al. · 2017 · Journal of Clinical Investigation
  10. Lipoatrophy Revisited
    Reitman, Marc L., Arioglu, Elif, Gavrilova, Oksana, Taylor, Simeon I. · 2000 · Trends in Endocrinology & Metabolism
  11. Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease
    Roberto Catanzaro, Biagio Cuffari, Angelo Italia, Francesco Marotta · 2016 · World Journal of Gastroenterology
  12. Lipid metabolism and signaling in cardiac lipotoxicity
    Kenneth D’Souza, Carine Nzirorera, Petra C. Kienesberger · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  13. Nonalcoholic fatty liver disease: A comprehensive review of a growing epidemic
    Kareem Hassan · 2014 · World Journal of Gastroenterology
  14. Evidence of Early Alterations in Adipose Tissue Biology and Function and Its Association With Obesity-Related Inflammation and Insulin Resistance in Children
    Kathrin Landgraf, Denise Rockstroh, Isabel Viola Wagner, Sebastian Weise, Roy Tauscher, Julian Tristan Schwartze, Dennis Löffler, Ulf Bühligen, Magdalena Wojan, Holger Till et al. · 2014 · Diabetes
  15. Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Müller Cell–Derived Inflammatory Cytokine Production in Diabetes
    Yimin Zhong, Jingming Li, Yan-Ming Chen, J. Wang, R. Ratan, Sarah X. Zhang · 2012 · Diabetes
  16. Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties
    Ondřej Kuda, Marie Březinová, Martina Rombaldová, Barbora Slavı́ková, Martin Pošta, Petr Beier, Petra Janovská, Jiří Veleba, Ján Kopecký, Eva Kudová et al. · 2016 · Diabetes
  17. Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance
    Maura Agostini, Erik Schoenmakers, Catherine Mitchell, István Szatmári, David B. Savage, Aaron G. Smith, Odelia Rajanayagam, Robert K. Semple, Jian’an Luan, Louise Bath et al. · 2006 · Cell Metabolism
  18. Intramuscular lipid metabolism, insulin action, and obesity
    Consitt, Leslie A., Bell, Jill A., Houmard, Joseph A. · 2009 · IUBMB Life
  19. Circulating regulatory T cells are reduced in obesity and may identify subjects at increased metabolic and cardiovascular risk
    Nana‐Maria Wagner, Gunnar Brandhorst, Frauke S. Czepluch, Mareike Lankeit, Christoph S. Eberle, Sebastian Herzberg, Vivien Faustin, Joachim Riggert, Michael Oellerich, Gerd P Hasenfuss et al. · 2013 · Obesity
  20. Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis
    Yuwei Jiang, Daniel C. Berry, Wei Tang, Jonathan M. Graff · 2014 · Cell Reports
  21. Adipocyte hypertrophy, fatty liver, and metabolic risk factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE)
    Anand, Sonia S., Tarnopolsky, Mark A., Rashid, Shirya, Schulze, Karleen M., Desai, Dipika, Mente, Andrew, Rao, Sandy, Yusuf, Salim, Gerstein, Hertzel C., Sharma, Arya M. · 2011 · PLoS ONE
  22. Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
    Olga Gealekman, Alison Burkart, My Chouinard, Sarah M. C. Nicoloro, Juerg Straubhaar, Silvia Corvera · 2008 · American Journal of Physiology-Endocrinology and Metabolism
  23. Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity
    Robert A. Scott, Tove Fall, Dorota Pasko, Adam Barker, Stephen J. Sharp, Larraitz Arriola, Beverley Balkau, Aurelio Barricarte, Inês Barroso, Heiner Boeing et al. · 2014 · Diabetes
  24. Fat cell turnover in humans
    Peter Arner, Kirsty L. Spalding · 2010 · Biochemical and Biophysical Research Communications
  25. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
    Amit R. Majithia, Jason A. Flannick, Peter Shahinian, Michael H. Guo, Mark‐Anthony Bray, Pierre Fontanillas, Stacey Gabriel, NHGRI JHS/FHS Allelic Spectrum Project, Evan D. Rosen, David Altshuler et al. · 2014 · Proceedings of the National Academy of Sciences
  26. Lipotoxicity in obesity and diabetes-related cardiac dysfunction
    Igor Zlobine, Keshav Gopal, John R. Ussher · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  27. Body Fat Distribution and Incident Cardiovascular Disease in Obese Adults
    Ian J. Neeland, Aslan Teyfik Turer, Colby R. Ayers, Jarett D. Berry, Anand K. Rohatgi, Sandeep R. Das, Amit Khera, Gloria Lena Vega, Darren K. McGuire, Scott M. Grundy et al. · 2015 · Journal of the American College of Cardiology
  28. Evidence of impaired adipogenesis in insulin resistance
    Xiaolin Yang, Per‐Anders Jansson, Ivan Nagaev, Maia M Jack, Eugénia Carvalho, Katharina Stibrant Sunnerhagen, Margaret C. Cam, Samuel W. Cushman, Ulf Smith · 2004 · Biochemical and Biophysical Research Communications
  29. NF-κB is important for TNF-α-induced lipolysis in human adipocytes
    Jurga Laurencikiene, Vanessa van Harmelen, Elisabet Arvidsson Nordström, Andrea Dicker, Blomqvist Lennart, Erik B. Näslund, Dominique Langin, Peter Arner, Mikael Rydén · 2007 · Journal of Lipid Research
  30. Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis
    Vila, Isabelle K., Badin, Pierre-Marie, Marques, Marie-Adeline, Monbrun, Laurent, Lefort, Corinne, Mir, Lucile, Louche, Katie, Bourlier, Virginie, Roussel, Balbine, Gui, Philippe et al. · 2014 · Cell Reports
  31. Functional implication of BMP4 expression on angiogenesis in malignant melanoma
    Tanja Rothhammer-Hampl, F Bataille, Thilo Spruß, Guenther Eissner, Anja‐Katrin Bosserhoff · 2006 · Oncogene
  32. The multifaceted activity of VEGF in angiogenesis – Implications for therapy responses
    Stijn Moens, Jermaine Goveia, Peter Conrad Stapor, Anna Rita Cantelmo, Peter Carmeliet · 2014 · Cytokine & Growth Factor Reviews
  33. Lymphocytes in obesity-related adipose tissue inflammation
    Antonios Chatzigeorgiou, Katia P. Karalis, Stefan Richard Bornstein, Triantafyllos Chavakis · 2012 · Diabetologia
  34. WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4
    Ann Hammarstedt, Shahram Hedjazifar, Lachmi E. Jenndahl, Silvia Gogg, John R. Grünberg, Birgit Gustafson, Eva Klimčáková, Vladimír Štich, Dominique Langin, Markku Laakso et al. · 2013 · Proceedings of the National Academy of Sciences
  35. Visceral adipocyte hypertrophy is associated with dyslipidemia independent of body composition and fat distribution in women
    Veilleux, Alain, Caron-Jobin, Maude, Noël, Suzanne, Laberge, Philippe Y., Tchernof, André · 2011 · Diabetes
  36. Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance
    Hannele Yki‐Järvinen · 2015 · Nutrients
  37. Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure
    Kai Sun, Christine M. Kusminski, Katherine Luby‐Phelps, Stephen B. Spurgin, Yu An, Qiong A Wang, William L. Holland, Philipp E. Scherer · 2014 · Molecular Metabolism
  38. Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
    Kyle Jablonski, Andrew D. Gaudet, Stephanie A. Amici, Phillip G. Popovich, Mireia Guerau‐de‐Arellano · 2016 · PLoS ONE
  39. Ovarian Hormone Status and Abdominal Visceral Adipose Tissue Metabolism
    André Tchernof, Annie Desmeules, Christian Richard, Philippe Yves Laberge, Marleen Daris, Jacques R. Mailloux, Caroline Rhéaume, Pierre Dupont · 2004 · The Journal of Clinical Endocrinology & Metabolism
  40. Adipose Tissue Dysfunction and Impaired Metabolic Health in Human Obesity: A Matter of Oxygen?
    Gijs H. Goossens, Ellen E. Blaak · 2015 · Frontiers in Endocrinology
  41. Genetic Predisposition for Type 2 Diabetes, but Not for Overweight/Obesity, Is Associated with a Restricted Adipogenesis
    Arner, Peter, Arner, Erik, Hammarstedt, Ann, Smith, Ulf · 2011 · PLoS ONE
  42. Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity
    E. Bazzan, G. Turato, M. Tiné, C. Radu, E. Balestro, Chiara Rigobello, D. Biondini, M. Schiavon, F. Lunardi, S. Baraldo et al. · 2017 · Respiratory Research
  43. GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects
    Pedro M. Moraes‐Vieira, Alan Saghatelian, Barbara B. Kahn · 2016 · Diabetes
  44. Apfeltyp erhöht Diabetes- und KHK-Risiko
    2017 · DMW - Deutsche Medizinische Wochenschrift
  45. Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor
    Helena Stabile, Stefania Maria Filomena Mitola, Emanuela Moroni, Mirella Belleri, Stefania Nicoli, Daniela Coltrini, Francesco Peri, Antonello Pessi, Laura Orsatti, Fabio Talamo et al. · 2006 · Blood
  46. Adipocyte Size Threshold Matters: Link with Risk of Type 2 Diabetes and Improved Insulin Resistance After Gastric Bypass
    Aurélie Cotillard, Christine Poitou, Adriana Torcivia, Jean‐Luc Bouillot, Arne Dietrich, Nora Klöting, Cécile Grégoire, Karine Lolmède, Matthias Blüher, Karine Clément · 2014 · The Journal of Clinical Endocrinology & Metabolism
  47. Insulin resistance with low cellular IRS‐1 expression is also associated with low GLUT4 expression and impaired insulin‐stimulated glucose transport 1
    Eugénia Carvalho, Per‐Anders Jansson, Ivan Nagaev, Anne‐marie Wenthzel, Ulf Smith · 2001 · The FASEB Journal
  48. Association of fat cell size and paracrine growth factors in development of hyperplastic obesity
    Brenda G. Marques, Dorothy Bouillon Hausman, Roy Joseph Martin · 1998 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  49. Restricted Adipogenesis in Hypertrophic Obesity
    Birgit Gustafson, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith · 2013 · Diabetes
  50. Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis
    Mikael Rydén, Johan W. E. Jocken, Vanessa van Harmelen, Andrea Dicker, Johan Hoffstedt, Mikael Wirén, Lennart Blomqvist, Aline Mairal, Dominique Langin, Ellen E. Blaak et al. · 2007 · American Journal of Physiology-Endocrinology and Metabolism
  51. The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans
    Birgit Gustafson, Ulf Smith · 2012 · Diabetes
  52. Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity
    Leanne Hodson, Sandy M. Humphreys, Fredrik Karpe, Keith N. Frayn · 2012 · Diabetes
  53. Four‐week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue
    Denis P. Blondin, Amani Daoud, Taryn R. Taylor, Hans Christian Tingelstad, Véronic Bézaire, Denis Richard, André C. Carpentier, Albert W. Taylor, Mary‐Ellen Harper, Céline Aguer et al. · 2016 · The Journal of Physiology
  54. Epicardial Fat in the Maintenance of Cardiovascular Health
    Yang Fang Wu, Aijun Zhang, Dale J. Hamilton, Tuo Deng · 2017 · Methodist DeBakey Cardiovascular Journal
  55. Adipocyte Fetuin-A Contributes to Macrophage Migration into Adipose Tissue and Polarization of Macrophages
    Priyajit Chatterjee, Soma Seal, Sandip Mukherjee, Rakesh Kundu, Sutapa Mukherjee, Sukanta Ray, Satinath Mukhopadhyay, Subeer S. Majumdar, Samir Bhattacharya · 2013 · Journal of Biological Chemistry
  56. Regulation of Early Adipose Commitment by Zfp521
    Sona Kang, Peter Åkerblad, Riku Kiviranta, Rana K. Gupta, Shingo Kajimura, Michael J. Griffin, Jie Min, Roland Baron, Evan D. Rosen · 2012 · PLoS Biology
  57. Obesity-associated Inflammation Induces microRNA-155 Expression in Adipocytes and Adipose Tissue: Outcome on Adipocyte Function
    Esma Karkeni, Julien Astier, Franck Tourniaire, Mouna El Abed, Béatrice Romier, Erwan Gouranton, Lin Wan, Patrick Borel, Jérôme Salles, Stéphane Walrand et al. · 2016 · The Journal of Clinical Endocrinology & Metabolism
  58. Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity
    Séverine Ledoux, Isabelle Quéguiner, Simon Msika, Sophie Caldérari, Pierre Rufat, Jean‐Marie Gasc, Pierre L. Corvol, Étienne Larger · 2008 · Diabetes
  59. Adipocyte Hypertrophy, Inflammation and Fibrosis Characterize Subcutaneous Adipose Tissue of Healthy, Non-Obese Subjects Predisposed to Type 2 Diabetes
    A. M. Josefin Henninger, Björn Eliasson, Lachmi E. Jenndahl, Ann Hammarstedt · 2014 · PLoS ONE
  60. Adipose tissue and metabolic alterations: regional differences in fat cell size and number matter, but differently: a cross-sectional study.
    Rydén, Mikael, Andersson, Daniel P., Bergström, Ingrid B., Arner, Peter · 2014 · The Journal of Clinical Endocrinology & Metabolism
  61. Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells
    Ann Hammarstedt, Timothy E. Graham, Barbara B. Kahn · 2012 · Diabetology & Metabolic Syndrome
  62. BMPs Promote Proliferation and Migration of Endothelial Cells via Stimulation of VEGF-A/VEGFR2 and Angiopoietin-1/Tie2 Signalling
    Y. Suzuki, Kévin Montagne, A. Nishihara, Tetsuro Watabe, K. Miyazono · 2007 · The Journal of Biochemistry
  63. TLR4 is a link between diabetes and Alzheimer’s disease
    Nanqu Huang, Hai Dan Jin, Shaoyu Zhou, Jingshan Shi, Feng Jie Jin · 2016 · Behavioural Brain Research
  64. Role of WNT pathway in the determination of human mesenchymal stem cells into preadipocytes
    Matthias Laudes · 2011 · Journal of Molecular Endocrinology
  65. Diabetes Risk Among Overweight and Obese Metabolically Healthy Young Adults
    Gilad Twig, Arnon B. Afek, Estela Derazne, Dorit Tzur, Tali Cukierman‐Yaffe, Hertzel C. Gerstein, Amir Tirosh · 2014 · Diabetes Care
  66. Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants
    Francisco José Ortega, María Moreno, Josep Maria Mercader, José María Moreno‐Navarrete, Núria Fuentes-Batllevell, Mònica Sabater, Wifredo Ricart, José Manuel Fernández‐Real · 2015 · Clinical Epigenetics
  67. Regulation of white adipogenesis and its relation to ectopic fat accumulation and cardiovascular risk
    Birgit Gustafson, Ulf Smith · 2015 · Atherosclerosis
  68. Early B-Cell Factor (O/E-1) Is a Promoter of Adipogenesis and Involved in Control of Genes Important for Terminal Adipocyte Differentiation
    Peter Åkerblad, Ulrika Lind, David Liberg, Krister Bamberg, Mikael Sigvardsson · 2002 · Molecular and Cellular Biology
  69. The Size of Large Adipose Cells Is a Predictor of Insulin Resistance in First‐Degree Relatives of Type 2 Diabetic Patients
    Jian Yang, Björn Eliasson, Ulf Smith, Samuel W. Cushman, Arthur Sherman · 2012 · Obesity
  70. MECHANISMS IN ENDOCRINOLOGY: Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes: a causal mechanism or an innocent bystander?
    Charlotte Brøns, Louise Groth Grunnet · 2016 · European Journal of Endocrinology
  71. Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease
    Adil Mardinoğlu, Alena Stančáková, Luca Andrea Lotta, Johanna Kuusisto, Jan Borén, Matthias Blüher, Nicholas J. Wareham, Ele Ferrannini, Per‐Henrik Groop, Markku Laakso et al. · 2017 · Cell Metabolism
  72. Adipocytes Secrete Leukotrienes
    Isabelle Mothe‐Satney, Chantal Filloux, Hind Amghar, Catherine Pons, Virginie Bourlier, Jean Galitzky, Paul André Grimaldi, Chloé C. Féral, Anne Bouloumié, Emmanuel VAN OBBERGHEN et al. · 2012 · Diabetes
  73. Functional annotation of the human fat cell secretome
    Ingrid A. Dahlman, Manuela Elsen, Norbert Tennagels, Marcus Korn, Barbara Brockmann, Henrike Sell, Jürgen Eckel, Peter Arner · 2012 · Archives of Physiology and Biochemistry
  74. Toll-Like Receptor 4 Knockout Mice Are Protected against Endoplasmic Reticulum Stress Induced by a High-Fat Diet
    Nicolas Pierre, Louise Deldicque, Caroline Barbé, Damien Naslain, Patrice D. Cani, Marc Francaux · 2013 · PLoS ONE
  75. Cidea improves the metabolic profile through expansion of adipose tissue
    Gustavo Abreu-Vieira, Alexander W. Fischer, Charlotte L. Mattsson, Jasper M. A. de Jong, Irina G. Shabalina, Mikael Rydén, Jurga Laurencikiene, Peter Arner, Barbara Cannon, Jan Nedergaard et al. · 2015 · Nature Communications
  76. Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro
    Srijan K. Pinnamaneni, Robert J. Southgate, Mark Anthony Febbraio, Matthew J. Watt · 2006 · Diabetologia
  77. Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology
    Falk Bernhard, Kathrin Landgraf, Nora Klöting, Antje Berthold, Petra G Buttner, Daniela Friebe, W. Kiess, Peter Louis Kovacs, Matthias Blüher, Antje Körner · 2012 · Diabetologia
  78. Direct Transcriptional Repression of Zfp423 by Zfp521 Mediates a Bone Morphogenic Protein-Dependent Osteoblast versus Adipocyte Lineage Commitment Switch
    William N. Addison, Martin Ming-Jen Fu, Helen X. Yang, Lin Zhao, Kenichi Nagano, Francesca Gori, Roland Baron · 2014 · Molecular and Cellular Biology
  79. The Differential Role of Hif1β/Arnt and the Hypoxic Response in Adipose Function, Fibrosis, and Inflammation
    Kevin Y. Lee, Stéphane Gesta, Jérémie Boucher, Xiaohui L. Wang, C. Ronald Kahn · 2011 · Cell Metabolism
  80. Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab
    Atsushi Ogata, Atsuyoshi Morishima, Toru Hirano, Yoshihiro Hishitani, Keisuke Hagihara, Yoshihito Shima, Masashi Narazaki, Toshio Tanaka · 2010 · Annals of the Rheumatic Diseases
  81. Evidence for a Relationship between VEGF and BMI Independent of Insulin Sensitivity by Glucose Clamp Procedure in a Homogenous Group Healthy Young Men
    Michaela Loebig, Johanna Klement, André Schmoller, Simone Betz, Nicole Heuck, Ulrich Schweiger, Achim Peters, Bernd Schultes, Kerstin M. Oltmanns · 2010 · PLoS ONE
  82. Family history of type 2 diabetes increases the risk of both obesity and its complications: is type 2 diabetes a disease of inappropriate lipid storage?
    Henna Cederberg, Alena Stančáková, Johanna Kuusisto, Markku Laakso, Ulf Smith · 2014 · Journal of Internal Medicine
  83. Hepatokines and non-alcoholic fatty liver disease
    Lebensztejn, Dariusz M., Flisiak-Jackiewicz, Marta, Białokoz-Kalinowska, Irena, Bobrus-Chociej, Anna, Kowalska, Irina · 2016 · Acta Biochimica Polonica
  84. Specific Inhibition of Hormone-Sensitive Lipase Improves Lipid Profile while Reducing Plasma Glucose
    Thomas H. Claus, Derek Lowe, Yin Tong Liang, Arthur I. Salhanick, Christine Keiper Lubeski, Ling Yang, Lynn Lemoine, Jian Zhu, Kevin B. Clairmont · 2005 · Journal of Pharmacology and Experimental Therapeutics
  85. Good fat/bad fat
    Craig James McClain, Shirish S. Barve, Ion V. Deaciuc · 2007 · Hepatology
  86. Obesity, Insulin Resistance, and Alzheimer's Disease
    Hildreth, Kerry L., Van Pelt, Rachael E., Schwartz, Robert S. · 2012 · Obesity
  87. Saturated- and n-6 Polyunsaturated-Fat Diets Each Induce Ceramide Accumulation in Mouse Skeletal Muscle: Reversal and Improvement of Glucose Tolerance by Lipid Metabolism Inhibitors
    Georgia Frangioudakis, J M Garrard, Katy Raddatz, Jerry L. Nadler, Todd W. Mitchell, Carsten Schmitz‐Peiffer · 2010 · Endocrinology
  88. Obesity and Cancer
    Ruth Percik, Michael Stümvoll · 2009 · Experimental and Clinical Endocrinology & Diabetes
  89. Epicardial adipose tissue in endocrine and metabolic diseases
    Gianluca Iacobellis · 2013 · Endocrine
  90. Antiangiogenic Actions of Vascular Endothelial Growth Factor-A 165 b, an Inhibitory Isoform of Vascular Endothelial Growth Factor-A, in Human Obesity
    Doan T M Ngo, Melissa G. Farb, Ryosuke Kikuchi, Shakun Karki, Stephanie Tiwari, Sherman Bigornia, David O. Bates, Michael P. LaValley, Naomi M. Hamburg, Joseph A. Vita et al. · 2014 · Circulation
  91. Lower Total Adipocyte Number but No Evidence for Small Adipocyte Depletion in Patients With Type 2 Diabetes
    Magdalena Pasarica, Hui Xie, David Hymel, George A. Bray, Frank L. Greenway, Éric Ravussin, Steven R. Smith · 2009 · Diabetes Care
  92. The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT
    John R. Grünberg, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith · 2014 · Journal of Biological Chemistry
  93. BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue
    Jenny M. Hoffmann, John R. Grünberg, CHRISTOPHER D. CHURCH, Ivet Elias, Vilborg Pálsdóttir, John‐Olov Jansson, Fátima Bosch, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith · 2017 · Cell Reports
  94. Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects
    Mikael Rydén, Daniel Peter Andersson, Samuel Bernard, Kirsty L. Spalding, Peter Arner · 2013 · Journal of Lipid Research
  95. Metreleptin for injection to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy
    Cristina Adelia Meehan, Elaine K. Cochran, Andrea Kassai, Rebecca J. Brown, Phillip Görden · 2015 · Expert Review of Clinical Pharmacology
  96. Triglycerides in the Human Kidney Cortex: Relationship with Body Size
    I. A. Bobulescu, Y. Lotan, Jian-Ning Zhang, T. Rosenthal, J. Rogers, B. Adams-Huet, K. Sakhaee, O. Moe · 2014 · PLoS ONE
  97. Roles of Chronic Low-Grade Inflammation in the Development of Ectopic Fat Deposition
    Lulu Liu, Mei Mei, Shumin Yang, Qifu Li · 2014 · Mediators of Inflammation
  98. Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
    Saif Alhusaini, Kirsty C. McGee, Bruno Schisano, Alison L. Harte, Philip G. McTernan, Sudhesh Kumar, Gyanendra Tripathi · 2010 · Biochemical and Biophysical Research Communications
  99. Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population
    Tinashe Chikowore, Pedro Pisa, Tertia van Zyl, Edith J. M. Feskens, Edelweiss Wentzel‐Viljoen, Karin R. Conradie · 2017 · Nutrients
  100. Therapeutic Targets of Multiple Angiogenic Factors for the Treatment of Cancer and Metastasis
    Yihai Cao, Qi Liu · 2007 · Advances in cancer research
  101. Perivascular adipose tissue, inflammation and insulin resistance: link to vascular dysfunction and cardiovascular disease
    Guido Lastra, Camila Margarita Manrique · 2015 · Hormone Molecular Biology and Clinical Investigation
  102. Macrophage gene expression is related to obesity and the metabolic syndrome in human subcutaneous fat as well as in visceral fat
    Eva Klimčáková, B. Roussel, Z. Kovacova, Michaela Kováčiková, Michaela Šiklová, Marion Combes, Jindra Hejnová, Pauline Decaunes, Jean-José Maoret, T Vedral et al. · 2011 · Diabetologia
  103. Ectopic fat: the true culprit linking obesity and cardiovascular disease?
    Mariangela Morelli, Melania Gaggini, Giuseppe Daniele, Paolo Marraccini, Rosa Sicari, Amalia Gastaldelli · 2013 · Thrombosis and Haemostasis
  104. Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells
    Mae Sheikh‐Ali, Senan Sultan, Abdul-Razzak Alamir, Michael John Haas, Arshag D. Mooradian · 2010 · Nutrition
  105. Perivascular adipose tissue: An unique fat compartment relevant for the cardiometabolic syndrome
    Dorothea I. Siegel-Axel, Hans‐Ulrich Häring · 2016 · Reviews in Endocrine and Metabolic Disorders
  106. Relationship of visceral adipose tissue to metabolic risk factors for coronary heart disease: Is there a contribution of subcutaneous fat cell hypertrophy?
    Pascal Imbeault, Simone Lemieux, Denis Prud’homme, Angelo Tremblay, André Nadeau, Jean‐Pierre Després, Pascale Mauriège · 1999 · Metabolism
  107. Mechanistic link between nonalcoholic fatty liver disease and cardiometabolic disorders
    Soo Kyung Lim, Tae Jung Oh, Kwang Kon Koh · 2015 · International Journal of Cardiology
  108. New Evidence for the Role of Ceramide in the Development of Hepatic Insulin Resistance
    Karolina Konstantynowicz-Nowicka, Ewa Harasim‐Symbor, Marcin Baranowski, Adrian Chabowski · 2015 · PLoS ONE
  109. Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone
    Abdelkrim Khadir, Sina Kavalakatt, Jehad Ahmed Abubaker, Preethi Cherian, Dhanya Madhu, Irina Al‐Khairi, Mohamed Abu‐Farha, Samia Warsame, Naser B. Elkum, Mohammed Dehbi et al. · 2016 · Metabolism
  110. Early hematopoietic zinc finger protein—zinc finger protein 521: A candidate regulator of diverse immature cells
    Heather Mandy Bond, Maria Mesuraca, Nicola Amodio, Tiziana Mega, Valter Agosti, Delia Fanello, Daniela Pelaggi, Lars Bullinger, Michèle Grieco, Malcolm A.S. Moore et al. · 2007 · The International Journal of Biochemistry & Cell Biology
  111. Type 2 diabetes: Does pancreatic fat really matter?
    Valeria Guglielmi, Paolo Sbraccia · 2017 · Diabetes/Metabolism Research and Reviews
  112. Control of Adipose Tissue Expandability in Response to High Fat Diet by the Insulin-like Growth Factor-binding Protein-4
    Olga Gealekman, Kunal Gurav, My Chouinard, Juerg Straubhaar, Michael JW Thompson, Samir Malkani, Celia Hartigan, Silvia Corvera · 2014 · Journal of Biological Chemistry
  113. Bone morphogenetic protein 4 regulates microRNAs miR-494 and miR-126–5p in control of endothelial cell function in angiogenesis
    Erika Saretzki, Franziska Pankratz, Bianca Engert, Sebastian Grundmann, Christoph Bode, Martin Moser, Qian Zhou, Jennifer Susanne Esser · 2017 · Thrombosis and Haemostasis
  114. Lipodystrophies: adipose tissue disorders with severe metabolic implications
    Vı́ctor Cortés, Marta Fernández‐Galilea · 2015 · Journal of Physiology and Biochemistry
  115. Abdominal subcutaneous and omental adipocyte morphology and its relation to gene expression, lipolysis and adipocytokine levels in women
    Andréanne Michaud, Marie Michèle Boulet, Alain Veilleux, Suzanne Noël, Gaëtan Paris, André Tchernof · 2013 · Metabolism
  116. Traditional Anthropometric Parameters Still Predict Metabolic Disorders in Women With Severe Obesity
    Séverine Ledoux, Muriel Coupaye, Marie Essig, Simon Msika, Carine Roy, Isabelle Quéguiner, Christine Clérici, Étienne Larger · 2009 · Obesity
  117. Common and distinct regulation of human and mouse brown and beige adipose tissues: a promising therapeutic target for obesity
    Xuejiao Liu, Christopher L. Cervantes, Feng Liu · 2017 · Protein & Cell
  118. Numerous Genes in Loci Associated With Body Fat Distribution Are Linked to Adipose Function
    Ingrid A. Dahlman, Mikael Rydén, David Brodin, Harald Grallert, Rona J. Strawbridge, Peter Arner · 2016 · Diabetes
  119. Nutrition and the HIV-associated lipodystrophy syndrome
    Cathríona Loonam, Anne Mullen · 2012 · Nutrition Research Reviews
  120. Alterations in glucose transporter expression and function in diabetes: Mechanisms for insulin resistance
    Barbara B. Kahn · 1992 · Journal of Cellular Biochemistry
  121. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans
    Shakun Karki, Doan T M Ngo, Melissa G. Farb, Song‐Young Park, Samantha M. Saggese, Naomi M. Hamburg, Brian J. Carmine, Donald Thomas Hess, Kenneth Walsh, Noyan Gokce · 2017 · American Journal of Physiology-Heart and Circulatory Physiology
  122. Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner
    Junna Yamaguchi, Tetsuhiro Tanaka, Hisako Saito, Seitaro Nomura, Hiroyuki Aburatani, Hironori Waki, Takashi Kadowaki, Masaomi Nangaku · 2017 · Scientific Reports
  123. Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance
    John R. Grünberg, Jenny M. Hoffmann, Shahram Hedjazifar, Annika Nerstedt, Lachmi E. Jenndahl, Johannes Elvin, John J. Castellot, Lan Wei, Sofia Movérare‐Skrtic, Claes Ohlsson et al. · 2017 · Scientific Reports
  124. Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines
    Hui Zhang, M. Ram Sairam · 2014 · Hormone Molecular Biology and Clinical Investigation
  125. BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue
    Yan Tang, Shuwen Qian, Mengyuan Wu, Jue Wang, Ping Lü, Xi Li, Haiyan Huang, Liang Guo, Xia Sun, Congjian Xu et al. · 2016 · Journal of Molecular Cell Biology
  126. Interleukin-19 induces angiogenesis in the absence of hypoxia by direct and indirect immune mechanisms
    Farah Kako, Khatuna Gabunia, Mitali Ray, Sheri E. Kelemen, Ross N. England, Bashar Kako, Rosario G. Scalia, Michael V. Autieri · 2016 · American Journal of Physiology-Cell Physiology
  127. Induction of adipocyte hyperplasia in subcutaneous fat depot alleviated type 2 diabetes symptoms in obese mice
    Qiqi Lu, Mingming Li, Yu Shan Zou, Tong Cao · 2014 · Obesity
  128. CCN5, a secreted protein, localizes to the nucleus
    Kristina C. Wiesman, Wei Lan, Cassandra B. Baughman, Joshua W. Russo, Mark R. Gray, John J. Castellot · 2010 · Journal of Cell Communication and Signaling
  129. Relationship of Adipocyte Size with Adiposity and Metabolic Risk Factors in Asian Indians
    Ved Prakash Meena, V. Seenu, M. C. Sharma, Saumyaranjan Mallick, Ashu Seith Bhalla, Nandita Gupta, Anant Mohan, Randeep Guleria, Ravindra Mohan Pandey, Kalpana Luthra et al. · 2014 · PLoS ONE
  130. Adipocyte size is associated with NAFLD independent of obesity, fat distribution, and PNPLA3 genotype
    Elina M. Petäjä, Ksenia Sevastianova, Antti Hakkarainen, Marju Orho‐Melander, Nina M I Lundbom, Hannele Yki‐Järvinen · 2013 · Obesity
  131. The rediscovery of BAT in adult humans using imaging
    Kirsi A. Virtanen · 2016 · Best Practice & Research Clinical Endocrinology & Metabolism
  132. Family history of type 2 diabetes, abdominal adipocyte size and markers of the metabolic syndrome
    Pimjai Anthanont, Paola A. Ramos, Michael D. Jensen, Kazanna C. Hames · 2017 · International Journal of Obesity
  133. Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway
    Gail E. Kilroy, David H. Burk, Z. Elizabeth Floyd · 2016 · Journal of Biological Chemistry
  134. The effects of diet and lifestyle interventions on insulin resistance in patients with nonalcoholic fatty liver disease: a systematic review
    Tonya Paris, Elena S. George, Stuart Keith Roberts, Audrey C. Tierney · 2017 · European Journal of Gastroenterology & Hepatology
  135. Adipose cell size in obese Africans: evidence against the existence of insulin resistance in some patients.
    Barry I. Joffe, Ronald B Goldberg, J Feinstein, ALLAN E. KARK, Harold C Seftel · 1979 · Journal of Clinical Pathology
  136. Considerable disturbances of cardiovascular risk factors in women with diabetes and myocardial infarction
    Annika Dotevall, Lars Wilhelmsen, Georg Lappas, Annika Rosengren · 2005 · Journal of Diabetes and its Complications
  137. PReS-FINAL-2188: Insulin sensitivity is improved in sjia children with insulin resistance after tocilizumab treatment: results from the tender study
    Hoda Mirjafari, Nicolino Ruperto, Hermine I. Brunner, Zbigniew Michał Żuber, Francesco Zulian, María del Rocío Maldonado-Velázquez, Evangelia Mantzourani, Kevin J. Murray, J Roth, Josef Rovensky et al. · 2013 · Pediatric Rheumatology