Lipoatrophy Revisited

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405 · see citing works

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

Randle, P. J., Garland, P. B., Hales, C. N., & Newsholme, E. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)91500-9 · Cited by 5,093 · see citing works

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

Carr, A., Samaras, K., Burton, S., Law, M. G., Freund, J., Chisholm, D. J., & Cooper, D. A. (1998) · AIDS · doi:10.1097/00002030-199807000-00003 · Cited by 2,364 · see citing works

Environmental Contributions to the Obesity Epidemic

Hill, J. O., & Peters, J. C. (1998) · Science · doi:10.1126/science.280.5368.1371 · Cited by 2,206 · see citing works

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4318 · Cited by 2,164 · see citing works

Missense Mutations in the Rod Domain of the Lamin A/C Gene as Causes of Dilated Cardiomyopathy and Conduction-System Disease

Fatkin, D., MacRae, C. A., Sasaki, T., Wolff, M. R., Porcu, M., Frenneaux, M. P., Atherton, J. J., Vidaillet, H. J., Jr., Spudich, S., Girolami, U. D., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199912023412302 · Cited by 1,354 · see citing works

Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

Bonne, G., di Barletta, M. R., Varnous, S., Bécane, H. M., Hammouda, E.-H., Merlini, L., Francesco Muntoni, A., Greenberg, C. R., Gary, F., Urtizberea, J. A., et al. (1999) · Nature Genetics · doi:10.1038/6799 · Cited by 1,353 · see citing works

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

Shimomura, I., Hammer, R. E., Ikemoto, S., Brown, M. S., & Goldstein, J. L. (1999) · Nature · doi:10.1038/43448 · Cited by 1,038 · see citing works

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice.

Halaas, J. L., Boozer, C., Blair-West, J., Fidahusein, N., Denton, D. A., & Friedman, J. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8878 · Cited by 1,033 · see citing works

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

Shimomura, I., Hammer, R. E., Richardson, J. A., Ikemoto, S., Bashmakov, Y., Goldstein, J. L., & Brown, M. S. (1998) · Genes & Development · doi:10.1101/gad.12.20.3182 · Cited by 790 · see citing works

Life without white fat: a transgenic mousePreprint

Moitra, J., Mason, M. M., Olive, M., Krylov, D. Y., Gavrilova, O., Marcus‐Samuels, B., Feigenbaum, L., Lee, E., Aoyama, T., Eckhaus, M., et al. (1998) · Genes & Development · doi:10.1101/gad.12.20.3168 · Cited by 776 · see citing works

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy

Shackleton, S., Lloyd, D. J., Jackson, S. N. J., Evans, R. S., Niermeijer, M. F., Singh, B. M., Schmidt, H., Brabant, G. E., Kumar, S., Durrington, P. N., et al. (2000) · Nature Genetics · doi:10.1038/72807 · Cited by 701 · see citing works

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

Gavrilova, O., Marcus-Samuels, B., Graham, D., Kim, J. K., Shulman, G. I., Castle, A. L., Vinson, C., Eckhaus, M., & Reitman, M. L. (2000) · Journal of Clinical Investigation · doi:10.1172/jci7901 · Cited by 676 · see citing works

Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy

Cao, H. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.1.109 · Cited by 668 · see citing works

What if Minkowski Had Been Ageusic? An Alternative Angle on Diabetes

McGarry, J. D. (1992) · Science · doi:10.1126/science.1439783 · Cited by 657 · see citing works

Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Shimabukuro, M., Koyama, K., Chen, G., Wang, M.-Y., Trieu, F., Lee, Y., Newgard, C. B., & Unger, R. H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4637 · Cited by 646 · see citing works

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity.

Kopecky, J., Clarke, G., Enerbäck, S., Spiegelman, B., & Kozak, L. P. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118363 · Cited by 553 · see citing works

The Search for Human Obesity Genes

Comuzzie, A. G., & Allison, D. B. (1998) · Science · doi:10.1126/science.280.5368.1374 · Cited by 547 · see citing works

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

Katz, E. B., Stenbit, A. E., Hatton, K. S., DePinho, R. A., & Charron, M. J. (1995) · Nature · doi:10.1038/377151a0 · Cited by 467 · see citing works

Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice

Kim, J. K., Gavrilova, O., Chen, Y., Reitman, M. L., & Shulman, G. I. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.8456 · Cited by 443 · see citing works

Different Mutations in the LMNA Gene Cause Autosomal Dominant and Autosomal Recessive Emery-Dreifuss Muscular Dystrophy

di Barletta, M. R., Ricci, E., Galluzzi, G., Tonali, P. A., Mora, M., Morandi, L. O., Romorini, A., Voït, T., Ørstavik, K. H., Merlini, L., et al. (2000) · The American Journal of Human Genetics · doi:10.1086/302869 · Cited by 415 · see citing works

Troglitazone action is independent of adipose tissue.

Burant, C., Sreenan, S., Hirano, K., Tai, T. A., Lohmiller, J. J., Lukens, J. N., Davidson, N. O., Ross, S. R., & Graves, R. A. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119839 · Cited by 333 · see citing works

Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

Chen, G., Koyama, K., Yuan, X., Lee, Y., Zhou, Y.-T., O'Doherty, R. M., Newgard, C. B., & Unger, R. H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.25.14795 · Cited by 315 · see citing works

Efficacy and Safety of Troglitazone in the Treatment of Lipodystrophy Syndromes

Arioglu, E., Duncan-Morin, J., Sebring, N., Rother, K. I., Gottlieb, N., Lieberman, J., Herion, D., Kleiner, D. E., Reynolds, J., Premkumar, A., et al. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-133-4-200008150-00009 · Cited by 303 · see citing works

Generalized lipodystrophy, congenital and acquired (lipoatrophy)

Seip, M., & Trygstad, O. (1996) · Acta Paediatrica · doi:10.1111/j.1651-2227.1996.tb14262.x · Cited by 293 · see citing works

LIPODYSTROPHY AND HEPATOMEGALY WITH DIABETES, LIPÆMIA, AND OTHER METABOLIC DISTURBANCES

Lawrence, R. D. (1946) · The Lancet · doi:10.1016/s0140-6736(46)90528-4 · Cited by 287 · see citing works

Mutational and Haplotype Analyses of Families with Familial Partial Lipodystrophy (Dunnigan Variety) Reveal Recurrent Missense Mutations in the Globular C-Terminal Domain of Lamin A/C

Speckman, R. A., Garg, A., Du, F., Bennett, L. B., Veile, R. A., Oral, E. A., Taylor, S. I., Lovett, M., & Bowcock, A. M. (2000) · The American Journal of Human Genetics · doi:10.1086/302836 · Cited by 273 · see citing works

The Complement Abnormalities of Lipodystrophy

Sissons, J. G. P., West, R. J., Fallows, J., Williams, D. G., Boucher, B. J., Amos, N., & Peters, D. K. (1976) · New England Journal of Medicine · doi:10.1056/nejm197602262940902 · Cited by 269 · see citing works

Regulating Adipogenesis*

Mandrup, S., & Lane, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.9.5367 · Cited by 262 · see citing works

Torpor in mice is induced by both leptin-dependent and -independent mechanisms

Gavrilova, O., Leon, L. R., Marcus‐Samuels, B., Mason, M. M., Castle, A. L., Refetoff, S., Vinson, C., & Reitman, M. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14623 · Cited by 210 · see citing works

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.

Ogawa, Y., Masuzaki, H., Hosoda, K., Aizawa‐Abe, M., Suga, J., Suda, M., Ebihara, K., Iwai, H., Matsuoka, N., Satoh, N., et al. (1999) · Diabetes · doi:10.2337/diabetes.48.9.1822 · Cited by 205 · see citing works

A Gene for Congenital Generalized Lipodystrophy Maps to Human Chromosome 9q34

Garg, A., Wilson, R., Barnes, R., Arioǧlu, E., Zaidi, Z., Gürakan, F., Koçak, N., O’Rahilly, S., Taylor, S. I., Patel, S. B., et al. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.9.6103 · Cited by 192 · see citing works

Lipodystrophy in patients naive to HIV protease inhibitors

Madge, S., Loes, S. K., Mercey, D., Johnson, M. A., & Weller, I. V. D. (1999) · AIDS · doi:10.1097/00002030-199904160-00020 · Cited by 184 · see citing works

Mesenteric Lipodystrophy

KIPFER, R. E., MOERTEL, C. G., & DAHLIN, D. C. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-80-5-582 · Cited by 170 · see citing works

Inhibition of Adipocyte Differentiation by HIV Protease Inhibitors

Zhang, B., MacNaul, K. L., Szalkowski, D., Li, Z., Berger, J. P., & Moller, D. E. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.11.4274 · Cited by 165 · see citing works

Endocrine and Metabolic Evaluation of Human Immunodeficiency Virus-Infected Patients with Evidence of Protease Inhibitor-Associated Lipodystrophy

Yanovski, J. A., Miller, K. D., Kino, T., Friedman, T. C., Chrousos, G. P., Tsigos, C., & Falloon, J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5740 · Cited by 156 · see citing works

Familial partial lipodystrophy: two types of an X linked dominant syndrome, lethal in the hemizygous state.

Köbberling, J., & Dunnigan, M. G. (1986) · Journal of Medical Genetics · doi:10.1136/jmg.23.2.120 · Cited by 152 · see citing works

Transcriptional activation of adipogenesis

Wu, Z., Puigserver, P., & Spiegelman, B. M. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)00037-x · Cited by 138 · see citing works

Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity

Ross, S. R., Graves, R. A., & Spiegelman, B. M. (1993) · Trends in Genetics · doi:10.1016/0168-9525(93)90035-g · Cited by 136 · see citing works

Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity.Preprint

Ross, S. R., Graves, R. A., & Spiegelman, B. M. (1993) · Genes & Development · doi:10.1101/gad.7.7b.1318 · Cited by 134 · see citing works

Adverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV disease.

Vigouroux, C., Gharakhanian, S., Salhi, Y., Nguyen, T. H., Adda, N., Rozenbaum, W., & Capeau, J. (1999) · PubMed · Cited by 104 · see citing works

Leptin and diabetes in lipoatrophic mice

Gavrilova, O., Marcus-Samuels, B., Leon, L. R., Vinson, C., & Reitman, M. L. (2000) · Nature · doi:10.1038/35002663 · Cited by 88 · see citing works

HIV protease inhibitors block human preadipocyte differentiation, but not via the PPARgamma/RXR heterodimer

Wentworth, J. M., Burris, T. P., & Chatterjee, K. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.164r007 · Cited by 80 · see citing works

Early manifestations of the carbohydrate-deficient glycoprotein syndrome

Petersen, M. B., Brostrøm, K., Stibler, H., & Skovby, F. (1993) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)83488-2 · Cited by 69 · see citing works

Autosomal dominant partial lipodystrophy associated with Rieger anomaly, short stature, and insulinopenic diabetes

Aarskog, D., Ose, L., Pande, H., Eide, N. A., & Opitz, J. M. (1983) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320150104 · Cited by 58 · see citing works

Annular and semicircular lipoatrophies

Rongioletti, F., & Rebora, A. (1989) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(89)70053-0 · Cited by 49 · see citing works

Juvenile dermatomyositis associated with partial lipoatrophy

Kavanagh, G. M., Colaço, C. B., & Kennedy, C. (1993) · Journal of the American Academy of Dermatology · doi:10.1016/0190-9622(93)70052-u · Cited by 46 · see citing works

Partial Lipodystrophy and Dermatomyositis

Torrelo, A. (1991) · Archives of Dermatology · doi:10.1001/archderm.127.12.1846 · Cited by 41 · see citing works

Dysregulation of insulin-like growth factors in a case of generalized acquired lipoatrophic diabetes mellitus (Lawrence Syndrome) connected with autoantibodies against adipocyte membranes

Hübler, A., Abendroth, K., Keiner, T., STÖCKER, W., Kauf, E., Hein, G. P., & Stein, G. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1211955 · Cited by 40 · see citing works

Partial Lipodystrophy and Familial C3 Deficiency

McLean, R. H., & HOEFNAGEL, D. (1980) · Human Heredity · doi:10.1159/000153119 · Cited by 40 · see citing works

Transgenic Mice Overexpressing the 1-Adrenergic Receptor in Adipose Tissue Are Resistant to Obesity

Soloveva, V. (1997) · Molecular Endocrinology · doi:10.1210/me.11.1.27 · Cited by 36 · see citing works

Partial Lipodystrophy Associated with Juvenile Dermatomyositis: Report of Two Cases

Quecedo, E., Febrer, I., Serrano, G., Martinez‐Aparicio, A., & Aliaga, A. (1996) · Pediatric Dermatology · doi:10.1111/j.1525-1470.1996.tb00728.x · Cited by 35 · see citing works

Insulin-Resistant Diabetes Mellitus and Hypermetabolism in Mandibuloacral Dysplasia: A Newly Recognized Form of Partial Lipodystrophy*

Cutler, D. L., KAUFMANN, S., & Freidenberg, G. R. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-5-1056 · Cited by 34 · see citing works

SHORT syndrome and insulin resistance

Schwingshandl, J., Mache, C. J., Rath, K., & Borkenstein, M. H. (1993) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320470619 · Cited by 33 · see citing works

ABNORMAL BLOOD GLUCOSE REGULATION IN COCKAYNE'S SYNDROME

Cotton, R. B., Keats, T. E., & McCoy, E. E. (1970) · PEDIATRICS · doi:10.1542/peds.46.1.54 · Cited by 25 · see citing works

Late-onset lipoatrophic diabetes. Phenotypic and genotypic familial studies and effect of treatment with metformin and lispro insulin analog.

Vantyghem, M., Vigouroux, C., Magré, J., Desbois‐Mouthon, C., Pattou, F. N., Fontaine, P., Lefebvre, J., & Capeau, J. (1999) · Diabetes Care · doi:10.2337/diacare.22.8.1374 · Cited by 22 · see citing works

Barraquer-Simons syndrome (with sensorineural deafness): A contribution to the differential diagnosis of lipodystrophy syndromes

Spranger, S., Spranger, M., Tasman, A., Reith, W., Voigtländer, T., & Voigtländer, V. (1997) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19970905)71:4 · Cited by 19 · see citing works

Localized skin reactions to insulin: insulin lipodystrophies and skin reactions to pumped subcutaneous insulin therapy.

Levandoski, L. A., White, N. H., & Santiago, J. V. (1984) · PubMed · Cited by 18 · see citing works

Genetic Exclusion of 14 Candidate Genes in Lipoatropic Diabetes Using Linkage Analysis in 10 Consanguineous Families

Vigouroux, C. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.10.3438 · Cited by 16 · see citing works

Localized Lipoatrophy due to Recombinant Growth Hormone Therapy in a Child with 6.7 Kilobase Gene Deletion Isolated Growth Hormone Deficiency

Büyükgebiz, A., Aydın, A., Dündar, B. N., & Yörükoğlu, K. (1999) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.1999.12.1.95 · Cited by 9 · see citing works

A case of acquired partial lipodystrophy associated with localized scleroderma and undifferentiated connective tissue disease

Biasi, D., Caramaschi, P., Carletto, A., & Bambara, L. M. (1999) · Rheumatology International · doi:10.1007/s002960050106 · Cited by 9 · see citing works

Thiazolidinediones

Yki-Järvinen, H. (2004) · New England Journal of Medicine · doi:10.1056/nejmra041001 · Cited by 1,830 · see citing works

Leptin-Replacement Therapy for Lipodystrophy

Oral, E. A., Simha, V., Ruiz, E., Andewelt, A., Premkumar, A., Snell, P., Wagner, A. J., DePaoli, A. M., Reitman, M. L., Taylor, S. I., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012437 · Cited by 1,247 · see citing works

Fat Accumulation in the Liver Is Associated with Defects in Insulin Suppression of Glucose Production and Serum Free Fatty Acids Independent of Obesity in Normal Men

Seppala-Lindroos, A. (2002) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.7.3023 · Cited by 168 · see citing works

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

Combs, T. P., Berg, A. H., Obici, S., Scherer, P. E., & Rossetti, L. (2001) · Journal of Clinical Investigation · doi:10.1172/jci14120 · Cited by 935 · see citing works

Type 2 diabetes across generations: from pathophysiology to prevention and management

Nolan, C. J., Damm, P., & Prentki, M. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60614-4 · Cited by 923 · see citing works

Diabetes, Obesity, and the Brain

Schwartz, M. W., & Porte, D. (2005) · Science · doi:10.1126/science.1104344 · Cited by 841 · see citing works

Fatty Liver

Kotronen, A., & Yki‐Järvinen, H. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.147538 · Cited by 787 · see citing works

Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass

Gavrilova, O., Haluzı́k, M., Matsusue, K., Cutson, J. J., Johnson, L. K., Dietz, K. R., Nicol, C. J. B., Vinson, C., Gonzalez, F. J., & Reitman, M. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300043200 · Cited by 759 · see citing works

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ

Garofalo, R. S., Orena, S. J., Rafidi, K., Torchia, A. J., Stock, J. L., Hildebrandt, A. L., Coskran, T., Black, S. C., Brees, D. J., Wicks, J. R., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16885 · Cited by 726 · see citing works

Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

Petersen (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215001 · Cited by 622 · see citing works

Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin

Havel, P. J. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200202000-00008 · Cited by 575 · see citing works

Causes and Metabolic Consequences of Fatty Liver

Stefan, N., Kantartzis, K., & Häring, H. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0009 · Cited by 529 · see citing works

Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity

Hammarstedt, A., Gogg, S., Hedjazifar, S., Nerstedt, A., & Smith, U. (2018) · Physiological Reviews · doi:10.1152/physrev.00034.2017 · Cited by 462 · see citing works

Adipocyte Differentiation: From Fibroblast to Endocrine Cell

Gregoire, F. M. (2001) · Experimental Biology and Medicine · doi:10.1177/153537020122601106 · Cited by 433 · see citing works

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

Savage, D. B., Tan, G. D., Acerini, C. L., Jebb, S. A., Agostini, M., Gurnell, M., Williams, R., Umpleby, A. M., Thomas, E. L., Bell, J. D., et al. (2003) · Diabetes · doi:10.2337/diabetes.52.4.910 · Cited by 423 · see citing works

Insulin resistance and impaired adipogenesis

Gustafson, B., Hedjazifar, S., Gogg, S., Hammarstedt, A., & Smith, U. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.01.006 · Cited by 398 · see citing works

Leptin: Structure, Function and Biology

Zhang, F. P. Y., Chen, Y., Heiman, M. L., & DiMarchi, R. D. (2005) · Vitamins and hormones · doi:10.1016/s0083-6729(05)71012-8 · Cited by 343 · see citing works

Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of cardiovascular risk

Westerbacka, J., Corn�r, A., Tiikkainen, M., Tamminen, M., Vehkavaara, S., H�kkinen, A.-M., Fredriksson, J., & Yki-J�rvinen, H. (2004) · Diabetologia · doi:10.1007/s00125-004-1460-1 · Cited by 338 · see citing works

Variation in Type 2 Diabetes-Related Traits in Mouse Strains Susceptible to Diet-Induced Obesity

Rossmeisl, M., Rim, J. S., Koza, R. A., & Kozak, L. P. (2003) · Diabetes · doi:10.2337/diabetes.52.8.1958 · Cited by 283 · see citing works

Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease

Qureshi, K. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i26.3540 · Cited by 278 · see citing works

Fat in the liver and insulin resistance

Yki‐Järvinen, H. (2005) · Annals of Medicine · doi:10.1080/07853890510037383 · Cited by 267 · see citing works

Visceral fat and metabolic inflammation: the portal theory revisited

Item, F., & Konrad, D. (2012) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01035.x · Cited by 273 · see citing works

Analysis of paradoxical observations on the association between leptin and insulin resistance

Ceddia, R. B., Koistinen, H. A., Zierath, J. R., & Sweeney, G. (2002) · The FASEB Journal · doi:10.1096/fj.02-0158rev · Cited by 256 · see citing works

Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy

Maldergem, L. V., Magré, J., Khallouf, T. E., Gedde‐Dahl, T., Délepine, M., Trygstad, O., Seemanová, E., Stephenson, T. J., Albott, C. S., Bonńici, F., et al. (2002) · Journal of Medical Genetics · doi:10.1136/jmg.39.10.722 · Cited by 250 · see citing works

Leptin Function and Regulation

Zhang, Y., & Chua, S. C. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160041 · Cited by 270 · see citing works

Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?

Crux, N. B., & Elahi, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00832 · Cited by 243 · see citing works

Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy

Javor, E. D., Cochran, E. K., Musso, C., Young, J. R., DePaoli, A. M., & Gorden, P. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1994 · Cited by 226 · see citing works

Hypoadiponectinemia Is Associated with Insulin Resistance, Hypertriglyceridemia, and Fat Redistribution in Human Immunodeficiency Virus-Infected Patients Treated with Highly Active Antiretroviral Therapy

Addy, C., Gavrila, A., Tsiodras, S., Brodovicz, K. G., Karchmer, A. W., & Mantzoros, C. S. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020795 · Cited by 218 · see citing works

Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy

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Lipin Expression Preceding Peroxisome Proliferator-activated Receptor-γ Is Critical for Adipogenesis in Vivo and in Vitro

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