Protease-activated receptors in health and disease

Cites (635)

Items 201–400 of 635

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6. β-Arrestin-dependent Regulation of the Cofilin Pathway Downstream of Protease-activated Receptor-2
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8. Protease-Activated Receptor-1 Contributes to Cardiac Remodeling and Hypertrophy
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9. Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice
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11. Tumor Cell Invasion Is Promoted by Activation of Protease Activated Receptor-1 in Cooperation with the αvβ5 Integrin
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14. <i>Pseudomonas aeruginosa</i> Elastase Disables Proteinase-Activated Receptor 2 in Respiratory Epithelial Cells
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15. Interleukin-6 Production by Endothelial Cells via Stimulation of Protease-Activated Receptors Is Amplified by Endotoxin and Tumor Necrosis Factor-α
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16. Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells
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27. Kallikrein-related Peptidase 4 (KLK4) Initiates Intracellular Signaling via Protease-activated Receptors (PARs)
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28. Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function
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34. Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand
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36. Changes in the expression of protease‐activated receptor 1 and protease nexin‐1 mRNA during rat nervous system development and after nerve lesion
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37. Immune functions of the skin
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38. Localization of Protease-Activated Receptors -1 and -2 in Human Mast Cells: Indications for an Amplified Mast Cell Degranulation Cascade
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39. Mechanisms of Thrombin Receptor Agonist Specificity
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40. Protective Signaling by Activated Protein C Is Mechanistically Linked to Protein C Activation on Endothelial Cells
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41. Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice
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42. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)
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44. Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro
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46. Tryptase Activates the Mitogen-Activated Protein Kinase/Activator Protein-1 Pathway in Human Peripheral Blood Eosinophils, Causing Cytokine Production and Release
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47. Up-Regulation of Proteinase-Activated Receptor 1 Expression in Astrocytes During HIV Encephalitis
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48. A matrix metalloprotease‐PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis
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49. Role of Protease Activated Receptor 1 and 2 Signaling in Hypoxia-Induced Angiogenesis
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50. Coagulation and coagulation signalling in fibrosis
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51. Clathrin Adaptor AP2 Regulates Thrombin Receptor Constitutive Internalization and Endothelial Cell Resensitization
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52. Increased vascular permeability by a specific agonist of protease‐activated receptor‐2 in rat hindpaw
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53. Thrombin Receptor Activation Stimulates Astrocyte Proliferation and Reversal of Stellation by Distinct Pathways: Involvement of Tyrosine Phosphorylation
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54. Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways
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58. Neutrophil Elastase and Proteinase-3 Trigger G Protein-biased Signaling through Proteinase-activated Receptor-1 (PAR1)
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59. Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation
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61. Factor Xa stimulates fibroblast procollagen production, proliferation, and calcium signaling via PAR1 activation
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62. Trypsin Stimulates Integrin α5β1-dependent Adhesion to Fibronectin and Proliferation of Human Gastric Carcinoma Cells through Activation of Proteinase-activated Receptor-2
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63. Cloning of the cDNA encoding human brain trypsinogen and characterization of its product
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65. Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
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66. Cofactoring and Dimerization of Proteinase-Activated Receptors
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68. Functional Characterization and Expression Analysis of the Proteinase-Activated Receptor-2 in Human Cutaneous Mast Cells
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72. Evidence for the Presence of a Proteinase-Activated Receptor Distinct From the Thrombin Receptor in Vascular Endothelial Cells
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77. Protease-Activated Receptor-1–Mediated DNA Synthesis in Cardiac Fibroblast Is via Epidermal Growth Factor Receptor Transactivation
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78. Novel Agonists and Antagonists for Human Protease Activated Receptor 2
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83. Persistent Signaling by Dysregulated Thrombin Receptor Trafficking Promotes Breast Carcinoma Cell Invasion
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86. Proteinase‐activated receptor‐1 agonists attenuate nociception in response to noxious stimuli
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87. Trypsin IV or Mesotrypsin and p23 Cleave Protease-activated Receptors 1 and 2 to Induce Inflammation and Hyperalgesia
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89. Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
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90. Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-Dependent Mechanism in Mice
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91. Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle
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92. Multiple Independent Functions of Arrestins in the Regulation of Protease-Activated Receptor-2 Signaling and Trafficking
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93. A Rho Exchange Factor Mediates Thrombin and Gα12-induced Cytoskeletal Responses
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94. High density of tryptase‐positive mast cells in human colorectal cancer: a poor prognostic factor related to protease‐activated receptor 2 expression
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95. Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease
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96. PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke
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97. Application of classification schemes to the enteric nervous system
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98. Thrombin Receptor Activating Mutations
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99. Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage
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100. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells
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101. NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea
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102. The Clinical Significance of Cathepsin S Expression in Human Astrocytomas
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103. Proteolysis of the Exodomain of Recombinant Protease-Activated Receptors: Prediction of Receptor Activation or Inactivation by MALDI Mass Spectrometry
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108. Modulation of visceral pain and inflammation by protease‐activated receptors
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109. Neutrophils and the kallikrein–kinin system in proteinase‐activated receptor 4‐mediated inflammation in rodents
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110. Expression of Protease-Activated Receptor 2 in Ulcerative Colitis
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112. Evidence for tissue factor phosphorylation and its correlation with protease‐activated receptor expression and the prognosis of primary breast cancer
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