Protease-activated receptors in health and disease

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EGFR Antagonists in Cancer Treatment

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The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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A dual thrombin receptor system for platelet activation

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Vorapaxar in the Secondary Prevention of Atherothrombotic Events

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Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

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TRP channel activation by reversible covalent modification

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Molecular cloning of a potential proteinase activated receptor.

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Protease-activated receptor 3 is a second thrombin receptor in humans

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PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells

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Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

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Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway

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β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2

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Cloning and characterization of human protease-activated receptor 4

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The cytoprotective protein C pathway

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Impaired Pressure Sensation in Mice Lacking TRPV4

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Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

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Proteinase-Activated Receptor-2 Mediates Itch: A Novel Pathway for Pruritus in Human Skin

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Inflammation, endothelium, and coagulation in sepsis

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Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms

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Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin

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Interactions of Mast Cell Tryptase with Thrombin Receptors and PAR-2

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Role for protease activity in visceral pain in irritable bowel syndrome

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PAR3 is a cofactor for PAR4 activation by thrombin

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Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation

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Increased Platelet Reactivity and Circulating Monocyte-Platelet Aggregates in Patients With Stable Coronary Artery Disease

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Role of thrombin signalling in platelets in haemostasis and thrombosis

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Role of the thrombin receptor in development and evidence for a second receptor

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Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype

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Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

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TGF-β is a critical mediator of acute lung injury

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Generic GPCR residue numbers – aligning topology maps while minding the gaps

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Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases.

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Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

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G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets.

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Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

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High-resolution crystal structure of human protease-activated receptor 1

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Membrane fission by dynamin: what we know and what we need to know

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Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

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Visceral pain

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Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

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Thrombin receptor overexpression in malignant and physiological invasion processes

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Protease-Activated Receptor 2 Sensitizes the Capsaicin Receptor Transient Receptor Potential Vanilloid Receptor 1 to Induce Hyperalgesia

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Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

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Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.

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Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

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Impairment of Store-Operated Ca 2+ Entry in TRPC4 −/− Mice Interferes With Increase in Lung Microvascular Permeability

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Protease-activated receptors in inflammation, neuronal signaling and pain

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Essential role for proteinase-activated receptor-2 in arthritis

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A protective role for protease-activated receptors in the airways

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The Proteinase-activated Receptor 2 Is Induced by Inflammatory Mediators in Human Endothelial Cells

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Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

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Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain

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Cathepsin G Activates Protease-activated Receptor-4 in Human Platelets

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Molecular Cloning and Functional Expression of the Gene Encoding the Human Proteinase‐Activated Receptor 2

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Mast Cell Tryptase Controls Paracellular Permeability of the Intestine

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Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq–based resource for pain and sensory neuroscience research

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Inhibition of tissue factor signaling suppresses tumor growth

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Characterization of Protease-activated Receptor-2 Immunoreactivity in Normal Human Tissues

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Thrombin modulates and reverses neuroblastoma neurite outgrowth.

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Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2

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Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets

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Whole-genome sequencing of 128 camels across Asia reveals origin and migration of domestic Bactrian camels

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Ligation of protease-activated receptor 1 enhances v 6 integrin-dependent TGF- activation and promotes acute lung injury

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The Genetics of Chronic Itch: Gene Expression in the Skin of Patients with Atopic Dermatitis and Psoriasis with Severe Itch

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Biphasic Kinetics of Activation and Signaling for PAR1 and PAR4 Thrombin Receptors in Platelets

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Thrombin Induces Apoptosis in Cultured Neurons and Astrocytes via a Pathway Requiring Tyrosine Kinase and RhoA Activities

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Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain

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