Cardiovascular regulatory mechanisms in advanced age.

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Lakatta, E. G., & Levy, D. (2003) · Circulation · doi:10.1161/01.cir.0000048892.83521.58 · Cited by 2,244

Mechanisms, Pathophysiology, and Therapy of Arterial Stiffness

Zieman, S. J., Melenovsky, V., & Kass, D. A. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000160548.78317.29 · Cited by 1,854

Sarcopenia: Aging-Related Loss of Muscle Mass and Function

Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., Kirkland, J. L., & Sandri, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00061.2017 · Cited by 1,797

Arterial Aging: Is It an Immutable Cardiovascular Risk Factor?

Najjar, S. S., Scuteri, A., & Lakatta, E. G. (2005) · Hypertension · doi:10.1161/01.hyp.0000177474.06749.98 · Cited by 640

Impaired progenitor cell activity in age-related endothelial dysfunction

Heiss, C., Keymel, S., Niesler, U., Ziemann, J., Kelm, M., & Kalka, C. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.074 · Cited by 573

Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

Berkowitz, D. E., White, R., Li, D., Minhas, K. M., Cernetich, A., Kim, S., Burke, S., Shoukas, A. A., Nyhan, D., Champion, H. C., et al. (2003) · Circulation · doi:10.1161/01.cir.0000092948.04444.c7 · Cited by 486

How to assess sympathetic activity in humans

Grassi, G., & Esler, M. (1999) · Journal of Hypertension · doi:10.1097/00004872-199917060-00001 · Cited by 455

Age-associated Cardiovascular Changes in Health: Impact on Cardiovascular Disease in Older Persons

Lakatta, E. G. (2002) · Heart Failure Reviews · doi:10.1023/a:1013797722156 · Cited by 445

Senescence and Death of Primitive Cells and Myocytes Lead to Premature Cardiac Aging and Heart Failure

Chimenti, C., Kajstura, J., Torella, D., Urbanek, K., Heleniak, H., Colussi, C., Di Meglio, F., Nadal-Ginard, B., Frustaci, A., Leri, A., et al. (2003) · Circulation Research · doi:10.1161/01.res.0000093985.76901.af · Cited by 386

Effects of Aging on Mitochondrial DNA Copy Number and Cytochromec Oxidase Gene Expression in Rat Skeletal Muscle, Liver, and Heart

Barazzoni, R., Short, K. R., & Nair, K. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.5.3343 · Cited by 367

Restoration of Diastolic Function in Senescent Rat Hearts Through Adenoviral Gene Transfer of Sarcoplasmic Reticulum Ca2+-ATPase

Schmidt, U., del Monte, F., Miyamoto, M. I., Matsui, T., Gwathmey, J. K., Rosenzweig, A., & Hajjar, R. J. (2000) · Circulation · doi:10.1161/01.cir.101.7.790 · Cited by 230

Vascular senescence in cardiovascular and metabolic diseases

Katsuumi, G., Shimizu, I., Yoshida, Y., & Minamino, T. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00018 · Cited by 196

Effects of Aging on the Responsiveness of the Human Cardiac Sympathetic Nerves to Stressors

Esler, M. D., Thompson, J. M., Kaye, D. M., Turner, A. G., Jennings, G. L., Cox, H. S., Lambert, G. W., & Seals, D. R. (1995) · Circulation · doi:10.1161/01.cir.91.2.351 · Cited by 183

Meta-analysis of the effectiveness of the Trier Social Stress Test in eliciting physiological stress responses in children and adolescents

Seddon, J. A., Rodriguez, V. J., Provencher, Y., Raftery-Helmer, J., Hersh, J., Labelle, P. R., & Thomassin, K. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104582 · Cited by 117

Orthostatic hypotension in very old individuals living in nursing homes: the PARTAGE study

Valbusa, F., Labat, C., Salvi, P., Vivian, M. E., Hanon, O., & Benetos, A. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834d3d73 · Cited by 91

Ageing, the autonomic nervous system and arrhythmia: From brain to heart

Chadda, K. R., Ajijola, O. A., Vaseghi, M., Shivkumar, K., Huang, C. L.-H., & Jeevaratnam, K. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.09.005 · Cited by 77

Cardiac autonomic control and the effects of age, race, and sex: The CARDIA study

Sloan, R. P., Huang, M.-H., McCreath, H., Sidney, S., Liu, K., Dale Williams, O., & Seeman, T. (2008) · Autonomic Neuroscience · doi:10.1016/j.autneu.2008.01.006 · Cited by 65

Roadmap for alleviating the manifestations of ageing in the cardiovascular system

Liberale, L., Tual-Chalot, S., Sedej, S., Ministrini, S., Georgiopoulos, G., Grunewald, M., Bäck, M., Bochaton-Piallat, M.-L., Boon, R. A., Ramos, G. C., et al. (2025) · Nature Reviews Cardiology · doi:10.1038/s41569-025-01130-5 · Cited by 59

Contactless magnetocardiographic mapping in anesthetized Wistar rats: evidence of age-related changes of cardiac electrical activity

Brisinda, D., Caristo, M. E., & Fenici, R. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01048.2005 · Cited by 23

Attenuated sarcomere lengthening of the aged murine left ventricle observed using two-photon fluorescence microscopy

Nance, M. E., Whitfield, J. T., Zhu, Y., Gibson, A. K., Hanft, L. M., Campbell, K. S., Meininger, G. A., McDonald, K. S., Segal, S. S., & Domeier, T. L. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00315.2015 · Cited by 17