Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease
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Decreased fluid conservation increases vulnerability of older adults to syncope.
“The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [676]
An increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis increases vulnerability of older adults to syncope.
“The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [676]
Age-associated cardiovascular and autonomic changes increase vulnerability of older adults to syncope.
“The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [676]
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- Authors
- Lakatta, E. G., & Levy, D.
- Affiliations
- National Institutes of Health (US)
- Venue
- Circulation
- Published
- 2003-01-07
- Volume
- 107
- Issue
- 1
- Pages
- 139-146
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W3015544325
- Cited by
- 2,244
- References
- 47
- Citations by year
- 2026: 101 · 2025: 111 · 2024: 98 · 2023: 88 · 2022: 118 · 2021: 110 · 2020: 113 · 2019: 119 · 2018: 118 · 2017: 114 · 2016: 109 · 2015: 125 · 2014: 115 · 2013: 85 · 2012: 109
- FWCI
- 9.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- arterial aging, cardiac aging, cardiovascular disease, vascular aging
- MeSH terms
- Aged, Aging, Arteries, Arteriosclerosis, Blood Pressure, Carotid Arteries, Demography, Elasticity, Humans, Hypertension, Risk Factors, Vascular Diseases, Vasodilation, Prevalence
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