Cited by 2,244Cardiovascular Health and Disease PreventionCardiovascular Function and Risk FactorsCardiovascular Health and Risk Factors

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Lakatta, Edward G., Levy, Daniel·2003·Circulation

Integrity signals

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Crossref · 10.1161/01.cir.0000048892.83521.58

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47 of 47 references verified0 citation errors · 0 not checkable

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  • Decreased fluid conservation increases vulnerability of older adults to syncope.

    “The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”
  • An increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis increases vulnerability of older adults to syncope.

    “The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”
  • Age-associated cardiovascular and autonomic changes increase vulnerability of older adults to syncope.

    “The vulnerability of older adults to syncope increases because of age-associated cardiovascular and autonomic changes, decreased fluid conservation (45,671,676–678), and an increased probability of developing multiple concurrent morbidities (with their associated pharmacological treatments) that can overwhelm homeostasis.”

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Authors
Lakatta, E. G., & Levy, D.
Affiliations
National Institutes of Health (US)
Venue
Circulation
Published
2003-01-07
Volume
107
Issue
1
Pages
139-146
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W3015544325
Cited by
2,244
References
47
Citations by year
2026: 101 · 2025: 111 · 2024: 98 · 2023: 88 · 2022: 118 · 2021: 110 · 2020: 113 · 2019: 119 · 2018: 118 · 2017: 114 · 2016: 109 · 2015: 125 · 2014: 115 · 2013: 85 · 2012: 109
FWCI
9.48
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
arterial aging, cardiac aging, cardiovascular disease, vascular aging
MeSH terms
Aged, Aging, Arteries, Arteriosclerosis, Blood Pressure, Carotid Arteries, Demography, Elasticity, Humans, Hypertension, Risk Factors, Vascular Diseases, Vasodilation, Prevalence

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