The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
The Laboratory Diagnosis of Syphilis
Open accessAbstract
Syphilis has several clinical manifestations, making laboratory testing a very important aspect of diagnosis. In North America, many unsuspected cases are discovered by laboratory testing. The etiological agent, Treponema pallidum, cannot be cultured, and there is no single optimal alternative test. Serological testing is the most frequently used approach in the laboratory diagnosis of syphilis. The present paper discusses the various serological and alternative tests currently available along with their limitations, and relates their results to the likely corresponding clinical stage of the disease. The need to use multiple tests is discussed, and the importance of quality control is noted. The complexity of syphilis serology means that the services of reference laboratories and clinical experts are often needed.
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Sensitive detection of Treponema pallidum by using the polymerase chain reaction
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(2002) · PubMed · Cited by 159
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Cited by
Hussen, S., & Tadesse, B. T. (2019) · BioMed Research International · doi:10.1155/2019/4562385 · Cited by 63
Syphilis in pregnancy: The impact of “the Great Imitator”
Uku, A., Albujasim, Z., Dwivedi, T., Ladipo, Z., & Konje, J. C. (2021) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2021.01.010 · Cited by 39
Tsai, S., Sun, M. Y., Kuller, J. A., Rhee, E. H. J., & Dotters-Katz, S. (2019) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0000000000000713 · Cited by 36
Antibiotic therapy for adults with neurosyphilis
Buitrago-Garcia, D., Martí-Carvajal, A. J., Jimenez, A., Conterno, L. O., & Pardo, R. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011399.pub2 · Cited by 30
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