The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Where Have all the Antibiotics Gone?
Open accessAbstract
The discovery of antibiotics some 60 years ago was anticipated to herald the end of infectious diseases. However, microbial evolution and genetic jugglery have dispelled this notion; the constant increase in the appearance of resistant strains has not been matched by the introduction of new therapeutic agents. On the contrary, the dire need for novel antibiotics has coincided with a reduction in antibiotic discovery programs in the pharmaceutical industry. As a result, the treatment of microbial diseases has reached a point where many infections are essentially untreatable by the antimicrobial agents currently available. At the present time, numerous initiatives are being undertaken by physicians and by governments in an attempt to redress this situation. In addition, alternative approaches to antibiotics for the treatment of infectious diseases are being explored intensively.
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Citations
Cites
Sampling the Antibiotic Resistome
D'Costa, V. M., McGrann, K. M., Hughes, D. W., & Wright, G. D. (2006) · Science · doi:10.1126/science.1120800 · Cited by 1,594
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Combating Multidrug‐Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials
O'Connell, K. M. G., Hodgkinson, J. T., Sore, H. F., Welch, M., Salmond, G. P. C., & Spring, D. R. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201209979 · Cited by 435
New agents for the treatment of drug-resistant Mycobacterium tuberculosis
Hoagland, D. T., Liu, J., Lee, R. B., & Lee, R. E. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.026 · Cited by 328
Topical Antimicrobials for Burn Wound Infections
Dai, T., Huang, Y.-Y., K. Sharma, S., T. Hashmi, J., B. Kurup, D., & R. Hamblin, M. (2010) · Recent Patents on Anti-Infective Drug Discovery · doi:10.2174/157489110791233522 · Cited by 265
Joseph, R. J., Ser, H.-L., Kuai, Y.-H., Tan, L. T.-H., Arasoo, V. J. T., Letchumanan, V., Wang, L., Pusparajah, P., Goh, B.-H., Ab Mutalib, N.-S., et al. (2021) · Antibiotics · doi:10.3390/antibiotics10060719 · Cited by 68
Bacterial vaginosis: A state of microbial dysbiosis
Mondal, A. S., Sharma, R., & Trivedi, N. (2023) · Medicine in Microecology · doi:10.1016/j.medmic.2023.100082 · Cited by 44
Metadata
- Authors
- Davies, J.
- Venue
- Canadian Journal of Infectious Diseases and Medical Microbiology
- Publisher
- Wiley
- Published
- 2006-01
- Volume
- 17
- Issue
- 5
- Pages
- 287-290
- ISSN
- 1180-2332 (ISSN-L)
- 1712-9532
- 1918-1493
- OpenAlex
- W2126793166
- Cited by
- 228
- References
- 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
