Efficacy of Laparoscopic Mini Gastric Bypass for Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Open accessAbstract
Background. Controversies on the utility of laparoscopic mini gastric bypass (LMGB) in weight loss and type 2 diabetes mellitus (T2DM) control still exist.Methods. We conducted a comprehensive literature search of PubMed, EMBASE, and Cochrane Library. Review Manager was used to perform the meta-analysis and the weighted mean difference (WMD) and/or odds ratio with 95% confidence interval (95% CI) were used to evaluate the overall size effect.Results. The literature search identified 16 studies for systematic review and 15 articles for meta-analysis. Compared with LAGB, LSG, and LRYGB, LMGB showed significant weight loss [WMD, −6.58 (95% CI, −9.37, −3.79),P<0.01(LAGB); 2.86 (95% CI, 1.40, 5.83),P=0.004(LSG); 10.33 (95% CI, 4.30, 16.36),P<0.01(LRYGB)] and comparable/higher T2DM remission results [86.2% versus 55.6%,P=0.06(LAGB); 89.1% versus 76.3%,P=0.004(LAGB); 93.4% versus 77.6%,P=0.006(LAGB)]; LMGB also had shorter learning curve and less operation time than LRYGB [WMD, −35.2 (95% CI, −46.94, −23.46)].Conclusions. LMGB appeared to be effective in weight loss and T2DM remission and noninferior to other bariatric surgeries. However, clinical utility of LMGB needs to be further validated by future prospective randomized controlled trials.
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OAGB was associated with lower postoperative BMI compared with adjustable gastric banding (WMD -7 kg/m2, 95% CI -9 to -4).
“OAGB was associated with lower postoperative BMI (WMD − 7 kg/m2, 95% CI − 9 to − 4) and smaller waist circumference (WMD − 14 cm, 95% CI − 27 to − 1), whereas there was no difference in diabetes remission (RR 1.48, 95% CI 0.98 to 2.25) at a mean follow-up of 1 year (Supplementary Table S23).”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [115]
OAGB was associated with smaller waist circumference compared with adjustable gastric banding (WMD -14 cm, 95% CI -27 to -1).
“OAGB was associated with lower postoperative BMI (WMD − 7 kg/m2, 95% CI − 9 to − 4) and smaller waist circumference (WMD − 14 cm, 95% CI − 27 to − 1), whereas there was no difference in diabetes remission (RR 1.48, 95% CI 0.98 to 2.25) at a mean follow-up of 1 year (Supplementary Table S23).”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [115]
There was no difference in diabetes remission between OAGB and adjustable gastric banding at a mean follow-up of 1 year (RR 1.48, 95% CI 0.98 to 2.25).
“OAGB was associated with lower postoperative BMI (WMD − 7 kg/m2, 95% CI − 9 to − 4) and smaller waist circumference (WMD − 14 cm, 95% CI − 27 to − 1), whereas there was no difference in diabetes remission (RR 1.48, 95% CI 0.98 to 2.25) at a mean follow-up of 1 year (Supplementary Table S23).”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [115]
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Can bariatric surgery delay the need for knee replacement in morbidly obese osteoarthritis patients
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Surgical Management of Obesity: A Broad Overview of Bariatric and Metabolic Surgery
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Long-term Outcomes and Quality of Life Following Laparoscopic One-anastomosis Gastric Bypass
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- Authors
- Quan, Y., Huang, A., Ye, M., Xu, M., Zhuang, B., Zhang, P., Yu, B., & Min, Z.
- Affiliations
- Fudan University (CN)
- Corresponding author
- Quan, Yingjun
- Min, Zhijun
- Venue
- Gastroenterology Research and Practice
- Publisher
- Hindawi Limited
- Published
- 2015
- Volume
- 2015
- Pages
- 1-13
- ISSN
- 1687-6121 (ISSN-L)
- 1687-630X
- PMC
- PMC4488176
- OpenAlex
- W2154340533
- Cited by
- 93
- References
- 71
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 7 · 2022: 11 · 2021: 5 · 2020: 11 · 2019: 7 · 2018: 17 · 2017: 7 · 2016: 13 · 2015: 4
- FWCI
- 2.62
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Gastroenterology Research and Practice (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Keywords
- laparoscopic mini-gastric bypass, bariatric surgery, obesity, type 2 diabetes, weight loss, diabetes remission, laparoscopic adjustable gastric band, laparoscopic Roux-en-Y gastric bypass, learning curve, operative time
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