Cited by 203Sesquiterpenes and Asteraceae StudiesPhytochemistry and Biological ActivitiesPlant chemical constituents analysis

The DOI matches its Crossref record; 155 of the 156 references it cites were found in a registry or an index.

Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis

Open access

Ivanescu, Bianca, Miron, Anca, Corciova, Andreia·2015·Journal of Analytical Methods in Chemistry

DOI 10.1155/2015/247685PMC PMC4606394

Open this paper in CoChat — free account Open PDF

Abstract

Sesquiterpene lactones are a large group of natural compounds, found primarily in plants of Asteraceae family, with over 5000 structures reported to date. Within this family, genus Artemisia is very well represented, having approximately 500 species characterized by the presence of eudesmanolides and guaianolides, especially highly oxygenated ones, and rarely of germacranolides. Sesquiterpene lactones exhibit a wide range of biological activities, such as antitumor, anti-inflammatory, analgesic, antiulcer, antibacterial, antifungal, antiviral, antiparasitic, and insect deterrent. Many of the biological activities are attributed to the α-methylene-γ-lactone group in their molecule which reacts through a Michael-addition with free sulfhydryl or amino groups in proteins and alkylates them. Due to the fact that most sesquiterpene lactones are thermolabile, less volatile compounds, they present no specific chromophores in the molecule and are sensitive to acidic and basic mediums, and their identification and quantification represent a difficult task for the analyst. Another problematic aspect is represented by the complexity of vegetal samples, which may contain compounds that can interfere with the analysis. Therefore, this paper proposes an overview of the methods used for the identification and quantification of sesquiterpene lactones found in Artemisia genus, as well as the optimal conditions for their extraction and separation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1155/2015/247685

Cites

155 of 155 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Sesquiterpenoids Lactones: Benefits to Plants and People
Chadwick, M., Trewin, H., Gawthrop, F., & Wagstaff, C. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612780 · Cited by 698 · cited 4×
“NF-κB controls the response of other effectors such as cytokines, inflammatory molecules, and cell adhesion molecules [2].”
BackgroundInfluential
The Artemisia L. Genus: A Review of Bioactive Essential Oils
Abad, M. J., Bedoya, L. M., Ticona, L. A., & Bermejo, P. (2012) · Molecules · doi:10.3390/molecules17032542 · Cited by 620 · cited 1×
“Artemisia species are aromatic plants exploited for their volatile oil [12] and many of them are used all over the world in traditional medicine in order to treat conditions such as fever, malaria, inflammation, ulcer, diabetes, and intestinal worms.”
Background
The Molecular Mechanism of Action of Artemisinin—The Debate Continues
O’Neill, P. M., Barton, V., & Ward, S. A. (2010) · Molecules · doi:10.3390/molecules15031705 · Cited by 618 · cited 1×
“Artemisinin also targets the parasite mitochondria or the translationally controlled tumour protein and PfATP6, a parasite-encoded sarcoplasmic-endoplasmic reticulum calciumATPase, which is crucial for the development of the parasite [80].”
Background
What made sesquiterpene lactones reach cancer clinical trials?
Ghantous, A., Gali‐Muhtasib, H. U., Vuorela, H. J., Saliba, N. A., & Darwiche, N. (2010) · Drug Discovery Today · doi:10.1016/j.drudis.2010.06.002 · Cited by 618 · cited 2×
“Sesquiterpene lactones are a large group of natural compounds, found primarily in plants of Asteraceae family, with over 5000 structures reported to date.”
Background
Flavonoids from Artemisia annua L. as Antioxidants and Their Potential Synergism with Artemisinin against Malaria and Cancer
Ferreira, J., Luthria, D. L., Sasaki, T., & Heyerick, A. (2010) · Molecules · doi:10.3390/molecules15053135 · Cited by 532 · cited 1×
“One plant species usually produces one type of sesquiterpene lactones, found chiefly in leaves and flowers in concentrations of 0.01% to 8% dry weight [5, 10].”
BackgroundInfluential
The Antiviral Activities of Artemisinin and Artesunate
Efferth, T., Romero, M. R., Wolf, D. G., Stamminger, T., Marin, J. J. G., & Marschall, M. (2008) · Clinical Infectious Diseases · doi:10.1086/591195 · Cited by 503 · cited 1×
“Another NF-𝜅B inhibitor, artemisolide, was isolated from Artemisia asiatica by activity-guided fractionation using the NF-𝜅B mediated reporter gene assay [56, 57].”
Method
Molecular Modes of Action of Artesunate in Tumor Cell Lines
Efferth, T., Sauerbrey, A., Olbrich, A., Gebhart, E., Rauch, P., Weber, H. O., Hengstler, J. G., Halatsch, M., Volm, M., Tew, K. D., et al. (2003) · Molecular Pharmacology · doi:10.1124/mol.64.2.382 · Cited by 431 · cited 1×
“The 𝛾-lactone ring, usually with an 𝛼-methylene group, is a significant characteristic of SLs.”
Background
Artemisinins: their growing importance in medicine
Krishna, S., Bustamante, L. Y., Haynes, R. K., & Staines, H. M. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.07.004 · Cited by 396 · cited 1×
“Several in vitro studies showed that artemisinin has antiviral effect on hepatitis B and C viruses [92, 93], a range of human herpes viruses (human cytomegalovirus, herpes simplex virus type 1, and EpsteinBarr virus) [94–96], influenza virus A [97], and a bovine viral diarrhea virus [98] in the low micromolar range.”
Background
Biologically Active Substances from the GenusArtemisia
Tan, R. X., Zheng, W., & Tang, H. (1998) · Planta Medica · doi:10.1055/s-2006-957438 · Cited by 385 · cited 1×
“SLs barrelierin, artemalin, barrelin, and desoxyvulgarin from Artemisia barrelieri also exhibited anti-inflammatory activities [69].”
Background
Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
Crespo-Ortiz, M. D. P., & Wei, M. Q. (2011) · BioMed Research International · doi:10.1155/2012/247597 · Cited by 384 · cited 1×
“These pleiotropic effects can account for effectiveness of artemisinin compounds in multidrug resistant types of cancer [25].”
Background

Flagged first, then by citations

Show all 156 references

1 of the 156 references couldn’t be matched to a known paper.

Research works printed but not linked: 29

2011, Sesquiterpene lactones: diversity and their biological activities, 313
2011, Anticancer Research, 31, 4417
2005, Oncology Reports, 14, 1599
1995, Fitoterapia, 66, 142
1991, Fitoterapia, 62, 275
1997, Planta Medica, 63, 384
2010, Natural Products Chemistry, 76, 1710
1993, Biotechnology Therapeutics, 4, 77
2004, Eksperimental'naya i Klinicheskaya Farmakologiya, 67, 37
2011, Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 23, 460
2001, Zhonghua Jie He He Hu Xi Za Zhi, 24, 164
2009, Iranian Journal of Immunology, 6, 216
10.1002/(sici)1099-1565(199811/12)9:6lt;296::aid-pca421>3.0.co;2-m · DOI
2010, Oriental Journal of Chemistry, 26, 143
2010, International Journal of Pharma and Bio Sciences, 1
2010, Natural Product Sciences, 16, 143
2012, Journal of Pharmaceutical and Biomedical Sciences, 24, 6
2011, Eurasian Journal of Analytical Chemistry, 6, 104
2008, Journal of Vector Borne Diseases, 45, 281
2011, Journal of Chemical and Pharmaceutical Research, 3, 277
2008, Indian Journal of Chemical Technology, 15, 59
2009, Eurasian Journal of Analytical Chemistry, 4, 119
2008, African Journal of Biotechnology, 7, 3288
10.7324/japs.2013.3821 · DOI
2009, Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 8, 275
2006, Médecine Tropicale, 66, 602
2007, Records of Natural Products, 1, 36
2006, Revista Brasileira de Plantas Medicinais, 8, 119
2014, Annals of Biological Research, 5, 88

Sorted by citations

Items 101–200 of 203

Comparative Phytochemistry of Polyacetylenes of the Genus Artemisia (Asteraceae): Compounds with High Biological Activities and Chemotaxonomic Significance
Greger, H. (2025) · Molecules · doi:10.3390/molecules30030537 · Cited by 8
Current developments on the antimalarial, antileishmanial, and antitrypanosomal potential and mechanisms of action of Terminalia spp.
Tali, M. B. T., Kamdem, B. P., Tchouankeu, J. C., & Boyom, F. F. (2023) · South African Journal of Botany · doi:10.1016/j.sajb.2023.03.028 · Cited by 8
Artemdubinoids A–N: novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia
Gao, Z., Li, T.-Z., Ma, Y., Huang, X., Geng, C., Zhang, X., & Chen, J. (2023) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(23)60441-8 · Cited by 8
Isolation of Arborescin from Artemisia absinthium L. and Study of Its Antioxidant and Antimicrobial Potential by Use of In Vitro and In Silico Approaches
Hbika, A., Elbouzidi, A., Taibi, M., Ouahabi, S., Loukili, E. H., Bouyanzer, A., Yahyaoui, M. I., Asehraou, A., Hachlafi, N. E., Salamatullah, A. M., et al. (2024) · Separations · doi:10.3390/separations11070209 · Cited by 8
“9 of 22 The IR spectrum of the compound CR1 presented in Figure 2”
Background
Cadinenes and other metabolites from Verbesina sphaerocephala A. Gray
Arciniegas, A., Pérez‐Castorena, A., Villaseñor, J. L., & de Vivar, A. R. (2020) · Biochemical Systematics and Ecology · doi:10.1016/j.bse.2020.104183 · Cited by 8
Impact of sesquiterpene lactones on the skin and skin-related cells? A systematic review of in vitro and in vivo evidence
da Silva, L. P., Borges, B. A., Veloso, M. P., Chagas‐Paula, D. A., Gonçalves, R. V., & Novaes, R. D. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118815 · Cited by 9
Ornamental Asteraceae Species as New Sources of Secondary Metabolites
Burlec, A. F., ARSENE, C. C., Gille, E., Hăncianu, M., & Cioancă, O. (2017) · Indian Journal of Pharmaceutical Education and Research · doi:10.5530/ijper.51.3s.61 · Cited by 8
Effect of Plant Growth Regulators on Different Explants of Artemisia ludoviciana under Photoperiod and Darkness Conditions and Their Influence on Achillin Production
Sánchez‒Ramos, M., Berman-Bahena, S., Álvarez, L., Sánchez‐Carranza, J. N., Bernabé‐Antonio, A., Román‐Guerrero, A., Marquina‐Bahena, S., & Cruz‐Sosa, F. (2022) · Processes · doi:10.3390/pr10081439 · Cited by 7
Highly oxygenated antiplasmodial and non-hemolytic Δ7,9(11) stigmastane-type steroids from the twigs of Vernonia amygdalina Delile
Happi, G. M., Sikam, K. G., Dietl, A., Reinhardt, J. K., Dzouemo, L. C., Konfor, S. M., Rakhmanov, M., Wansi, J. D., & Teufel, R. (2024) · Phytochemistry · doi:10.1016/j.phytochem.2024.114286 · Cited by 7
Natural sesquiterpene lactones in prostate cancer therapy: mechanisms and sources
Kaushal, K., Kapoor, D. U., Kumar, S., Sony, A., Viswanath, A., Chaitanya, M., Singh, M., Singh, S. K., & Mazumder, A. (2025) · Medical Oncology · doi:10.1007/s12032-025-02740-2 · Cited by 7
Effects of exogenous indole‐3‐acetic acid on the density of trichomes, expression of artemisinin biosynthetic genes, and artemisinin biosynthesis in Artemisia annua
Guo, Z., Zhang, Q., Zhang, Y., Wu, C., Zheng, Y., Tong, F., Zhang, L., Lu, R., Pan, X., Tan, H., et al. (2023) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.2489 · Cited by 10
The First Phytochemical Investigation of Artemisia divaricate: Sesquiterpenes and Their Anti-Inflammatory Activity
Yan, S., Ke, C., Feng, Z., Tang, C., & Ye, Y. (2023) · Molecules · doi:10.3390/molecules28104254 · Cited by 7
“Sesquiterpenes, which are an essential class of secondary metabolites, have a wide distribution in plants, especially those of the Asteraceae family [2].”
Background
Determination of the antiplasmodial activity, cytotoxicity and active compound of Pechuel-loeschea leubnitziae O. Hoffm. (Asteraceae) of Namibia
Kadhila-Muandingi, N. P., Sekhoacha, M. P., Tselanyane, M., Chinsembu, K. C., & Molefe-Khamanga, D. M. (2020) · SN Applied Sciences · doi:10.1007/s42452-020-2926-6 · Cited by 7
Artemordosins A−L, cadinane-monoterpene heterodimers and sesquiterpenoids with antihepatoma activity from Artemisia ordosica
Wang, Y., Li, T.-Z., Ma, Y., Geng, C., Wang, Y. Q., & Chen, J. (2024) · Phytochemistry · doi:10.1016/j.phytochem.2024.114374 · Cited by 6
Furofuran lignans of Artemisia genus: Isolation, biosynthesis and biological activity
Ickovski, J. D., Pavlović, J., Mitić, M., Palić, I. R., Kostić, D. A., Petrović, G. M., & Stojanović, G. (2020) · Journal of the Serbian Chemical Society · doi:10.2298/jsc191210009i · Cited by 6
Sesquiterpene Lactones and Flavonoid from the Leaves of Basin Big Sagebrush (Artemisia tridentata subsp. tridentata): Isolation, Characterization and Biological Activities
Anibogwu, R., Jesus, K. D., Pradhan, S., Leuven, S. V., & Sharma, K. (2024) · Molecules · doi:10.3390/molecules29040802 · Cited by 6
“They constitute a diverse set of biologically active compounds and have been reported to show a wide range of biological activities, including cytotoxic, anti-inflammatory, antifungal, antibacterial, antimalarial and phytotoxic properties [17].”
Background
Sesquiterpenes and prostate cancer
Uzun, K., Bilen, C. Y., & Yalçın, F. N. (2025) · Phytochemistry Reviews · doi:10.1007/s11101-025-10088-8 · Cited by 6
Costunolide inhibits the progression of TPA-induced cell transformation and DMBA/TPA-induced skin carcinogenesis by regulation of AKT-mediated signaling
Wi, K., Hwang, S., Kim, Y.-G., Lee, S.-I., Lee, C., Bang, G., Lee, J., & Lee, M. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03742-w · Cited by 6
“Sesquiterpene lactones, a class of phytochemicals found in diverse plants, have attracted attention for their anti-inflammatory, antioxidant, and significantly, anticancer effects [16–20].”
Phenolics and eudesmanolide from aged common sage exudate with sugar
Kim, T. Y., Cho, J., Lee, Y. G., Jeong, H. Y., Lee, H. J., & Moon, J. (2017) · Food Science and Biotechnology · doi:10.1007/s10068-017-0234-8 · Cited by 6
Effects of diet on skin sensitization by nickel, poison ivy, and sesquiterpene lactones
An, N., Pourzal, S., Luccioli, S., & Vukmanović, S. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111137 · Cited by 6
Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review
Singh, G., Sharma, V., & Nnenna, U. B. (2026) · BioMed Research International · doi:10.1155/bmri/6998034 · Cited by 5
Magic bullets, magic shields, and antimicrobials in between
Prathapan, P. (2022) · Pharmaceutical Science Advances · doi:10.1016/j.pscia.2022.100002 · Cited by 5
“Artemisinin, a new, highly effective antimalarial compound, is a sesquiterpene lactone found in Artemisia annua [83].”
Germacrane-type sesquiterpenes from Artemisia atrovirens and their anti-inflammatory activity
Tang, C., Zheng, Y., Shao, Z., Ke, C., Feng, Z., & Yang, Y. (2024) · Fitoterapia · doi:10.1016/j.fitote.2024.106241 · Cited by 5
Dual Regulation of Cell Death and Cell Survival upon Induction of Cellular Stress by Isopimara-7,15-Dien-19-Oic Acid in Cervical Cancer, HeLa Cells In vitro
Abu, N., Yeap, S. K., Pauzi, A. Z. M., Akhtar, M. N., Zamberi, N. R., Ismail, J., Zareen, S., & Alitheen, N. B. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00089 · Cited by 5
“Collectively, Isopimara-7,15-Dien-19-Oic Acid managed to induce cellular stress in HeLa cells and activate several anti- and pro survival pathways.”
BackgroundResultInfluential
Effects on Other Microorganisms
Castelli, M. V., & López, S. N. (2018) · Springer eBooks · doi:10.1007/978-3-319-78274-4_12 · Cited by 5
Identification and characterization of a novel sesquiterpene synthase, 4-amorphen-11-ol synthase, from Artemisia maritima
Muangphrom, P., Seki, H., Matsumoto, S., Nishiwaki, M., Fukushima, E. O., & Muranaka, T. (2018) · Plant Biotechnology · doi:10.5511/plantbiotechnology.18.0324a · Cited by 5
“Previous studies have suggested that artemisinin is also produced in other Artemisia plant species (Arab et al. 2006; Dilshad et al. 2015; El Maggar 2012; Ivanescu et al. 2015; Mannan et al. 2010).”
Background
Analytical Procedures
Sülsen, V. P., Catalán, C. A. N., & Martino, V. S. (2018) · Springer eBooks · doi:10.1007/978-3-319-78274-4_6 · Cited by 5
Fermentation utilizing engineered microbes: revolutionizing the production of commercial products from plant-derived bioactive compounds
Chen, A., & Yuan, J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15584-0.00006-9 · Cited by 4
Computational approach for the evaluation of sesquiterpene lactone as a modulator of cannabinoid receptor type 2 for neurodegenerative disease prophylactics
Shrestha, R. L., Tamang, A., Dhital, S., Parajuli, N., Poudel, M., Adhikari, S., Shiva, M. C., Shrestha, A., Shrestha, T., Bharati, S., et al. (2025) · Molecular Diversity · doi:10.1007/s11030-025-11191-w · Cited by 4
In Vitro Antimalarial Activity and Phytochemical Analysis of Aerial Parts of Artemisia fragrans Willd.
Akbari, P., Asnaashari, S., Rahimpour, Y., & Asgharian, P. (2022) · Jundishapur Journal of Natural Pharmaceutical Products · doi:10.5812/jjnpp.117597 · Cited by 4
“Terpenes, particularly sesquiterpenes characterized by several Asteraceae species, especially the Artemisia genus, are highly diverse and abundant (26).”
Comparative study of different hexane extracts from Algerian Artemisia absinthium and Artemisia herba-alba : GC-MS profile, artemisinin content, and antioxidant properties
Belyagoubi-Benhammou, N., Zitouni-Nourine, S. H., Belyagoubi, L., Kebiri, H., Tahar, S. O., Marco, G. D., D’Agostino, A., Canini, A., & Gismondi, A. (2024) · Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology · doi:10.1080/11263504.2024.2384967 · Cited by 4
“A total of 839 phytochemicals have been isolated from 14 different species of Artemisia spp. using different techniques, such as HPLC-MS, GC-MS, HPLC-DAD, X-ray crystallography, and 1D and 2D NMR; these approaches have demonstrated that oxygenated terpenoids and hydrocarbons are the most abundant phy-toconstituents of…”
Artemisia: A Comprehensive Review of Phytochemistry, Medicinal Properties, and Biological Activities
Al‐Sowayan, N. S., Al-Harbi, F., & Alrobaish, S. A. (2024) · Journal of Biosciences and Medicines · doi:10.4236/jbm.2024.1211040 · Cited by 4
Botanical remedies ameliorate oxidative stress, immune response, and histopathology in Clarias gariepinus exposed to pyrogallol
Hamed, M., Said, R. E. M., Kotob, M. H., & Sayed, A. E. H. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126628 · Cited by 4
Diversity of chemical skeletons
Kotkar, G. D., Shetgaonkar, A. D., & Tilve, S. G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-15232-0.00023-0 · Cited by 4
PROMISING BIOLOGICAL ACTIVITIES OF SESQUITERPENE LACTONES
Burlec, A. F., Cioancă, O., Enache, L. C., & Hăncianu, M. (2017) · The Medical-Surgical Journal · Cited by 4
SESQUITERPENE LACTONS FROM AERIAL PARTS OF ARTEMISIA CAMPESTRIS (var. MARSCHALLIANA) SPRENG.
Kerimli, E. H., Aleskerova, A. N., & Serkerov, S. V. O. (2022) · chemistry of plant raw material · doi:10.14258/jcprm.20220210567 · Cited by 4
Functional and Mechanistic Studies of Two Anti-coccidial Herbs, Bidens pilosa and Artemisia indica
Yang, M., Lin, Y.-X., Yang, G. L., Kuo, T., Liang, Y.-C., Lee, T., Chang, C. L., & Yang, W. (2021) · Planta Medica · doi:10.1055/a-1527-9715 · Cited by 4
“The best known example is Artemisia annua and its compound artemisinin, which are commonly used to treat malaria [11].”
Background
Discovery of rearranged eudesmane-type sesquiterpenes from Artemisia tournefortiana
Kuerban, G., Turak, A., Xu, N., Tang, D., Zang, D., Abulimiti, X., Zhao, J., & Aisa, H. A. (2025) · Phytochemistry · doi:10.1016/j.phytochem.2025.114627 · Cited by 3
Antioxidant, antimicrobial, and toxicity profile of essential oils from endemic Moroccan Artemisia herba-alba
Saidi, S., Drioiche, A., Remok, F., Eddamsyry, B., Siddique, F., Amine, S., Gourich, A. A., Asbabou, A., Dawoud, T. M. S., Bourhia, M., et al. (2025) · International Journal of Food Properties · doi:10.1080/10942912.2025.2559051 · Cited by 3
Vernonia sesquiterpene lactones: a review of their chemical and pharmacological aspects
Happi, G. M., Sikam, K. G., Wansi, J. D., & Teufel, R. (2025) · Phytochemistry Reviews · doi:10.1007/s11101-025-10101-0 · Cited by 3
“The classiﬁcation of SLs according to their carbon skeleton helps in distinguishing several classes derived from germacrene A acid (GAA), which features a 10-mem-bered ring and is the biogenetic precusor for most SLs (Ivanescu et al. 2015) (Fig.”
Chemistry of Red Sanders
Pullaiah, T., Reddy, V. D., Umalatha, & Rashmi, B. S. (2019) · Springer eBooks · doi:10.1007/978-981-13-7627-6_4 · Cited by 3
Corchorus olitorius aqueous extract attenuates quorum sensing-regulated virulence factor production and biofilm formation
Al-Yousef, H. M., Alam, P., Khanam, Z., Amina, M., & Hassan, W. (2021) · Asian Pacific Journal of Tropical Biomedicine · doi:10.4103/2221-1691.303605 · Cited by 3
Exploring the Use of Medicinal Plants and Their Bioactive Derivatives as Alveolar NLRP3 Inflammasome Regulators during Mycobacterium tuberculosis Infection
Mvubu, N. E., & Chiliza, T. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179497 · Cited by 3
Antitumor Activity of Species of the Genus Artemisia L.: Current State and Prospects (Review)
Романтеева, Ю. В., Berezutsky, М. А., & Kurchatova, M. N. (2023) · Drug development & registration · doi:10.33380/2305-2066-2023-12-1-40-51 · Cited by 4
UPLC–QTOF/MS tentative identification of phytochemicals from Vernonia amygdalina Delile acetone and ethanol leaf extracts
Mkhonto, C., Makananise, V., Sagbo, I. J., Mashabela, N. M., Ndhlovu, P. T., Kubheka, B. P., & Otang-Mbeng, W. (2023) · Journal of Medicinal Plants for Economic Development · doi:10.4102/jomped.v7i1.181 · Cited by 3
The Phytochemical and Functional Characterization of the Aerial Parts of Artemisa alba Turra (Asteraceae) Grown in Romania
Țicolea, M., Pop, R. M., Pârvu, M., Usatiuc, L.-O., Uifălean, A., Brito, V. A., Fischer‐Fodor, E., Ranga, F., Rusu, C. C., Crişan, M., et al. (2025) · Foods · doi:10.3390/foods14081389 · Cited by 2
LC-MS/TOF Characterization and Stability Study of Artesunate in Different Solvent Systems
Oke, K., & Mugweru, A. M. (2022) · Separations · doi:10.3390/separations9080218 · Cited by 2
THE PLANT ARTEMISIA ANNUA (“SWEET WORMWOOD”) KAZAKHSTAN’S SOURSE OF BIOACTIVE COMPOUNDS POTENTIALLY CURE THE SARS-CoV-2 INFECTION
Maftakhova, A., Syzdykova, L., КЕЕР, В. В., Shustov, A. V., & Zhurinov, M. Z. (2022) · Eurasian journal of applied biotechnology · doi:10.11134/btp.3.2022.4 · Cited by 2
Unfolding phenolics biosynthetic plasticity of Artemisia alba Turra through plant tissue culture techniques
Trendafilova, A. B., Todorova, M. N., Wolfram, E., Peter, S., Ivanova, V., & Danova, K. (2024) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-024-02756-y · Cited by 2
“The main phytochemical classes of secondary metabolites characteristic for the genus are terpenoids, flavonoids, coumarins, caffeoylquinic acids, sterols and acetylenes (Bora and Sharma 2011; Ivanescu et al. 2015; Danova 2020).”
The Potential of Natural Products in Metabolic Disease Management: A Thorough Exploration of the Case of Uganda
Ahikiriza, A. A., Bukke, S. P. N., Yadesa, T. M., Nicholas, B., Daniel, K., Moses, K., Ddumba, S. M. B., & Prabhakar, P. K. (2025) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303320109241014064209 · Cited by 2
Specialized natural product analysis and chemophenetics of some Turkish endemic Centaurea L. (Asteraceae) taxa by electrospray ionization mass spectrometry fingerprinting and liquid chromatography-tandem mass spectrometry
Güzel, Y. (2020) · Biochemical Systematics and Ecology · doi:10.1016/j.bse.2020.104079 · Cited by 2
Development of Optimal Technology for Drying Herbal Medicinal Raw Materials from Autumn Wormwood (Artemisia serotina Bunge) Based on Comparative Analysis
Kadyrbay, A., Sakipova, Z. B., Krishtanova, N. A., Ibragimova, L., Ibrayeva, M. B., САКИПОВ, А. Е., Bekbolatova, E., Ridvanov, C., Сермухамедова, О. В., Adilbek, Y., et al. (2023) · Drug development & registration · doi:10.33380/2305-2066-2023-12-4-1578 · Cited by 2
Bio-guided isolation of a new sesquiterpene from Artemisia cina with anthelmintic activity against Haemonchus contortus L 3 infective larvaePreprint
la Pava, L. D. A.-D., González‐Cortazar, M., Zamilpa, A., Cuéllar-Ordaz, J. A., de la Crúz-Crúz, H. A., Higuera-Piedrahita, R. I., & López‐Arellano, R. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.26.582230 · Cited by 2
Synthesis and Biological Evaluation of Desacetylmatricarin Derivatives Isolated from Basin Big Sagebrush
Paucar, N. E., Leuven, S. V., Jesus, K. D., Pashikanti, S., Mateen, S., Pradhan, S., & Sharma, K. (2024) · Separations · doi:10.3390/separations11070217 · Cited by 1
Synthesis of new biologically active compounds based on α - santonin
Adekenov, S. M. (2025) · chemistry of plant raw material · doi:10.14258/jcprm.20250116408 · Cited by 1
“Меха-низм фармакологического действия α - сантонина (1) связывают с липофильностью сесквитерпеноида и его способностью проникать через плазматическую мембрану и, следовательно, взаимодействовать с внутри-клеточными рецепторами паразита [30, 31].”
Pharmacological insights into deoxyelephantopin: a multifunctional sesquiterpene with therapeutic promise in cancer and neurodegenerative disorders
Priyadarshni, A., Sharma, R., Bora, K. S., & Dewangan, H. K. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-11700-6 · Cited by 1
Synergistic anti-cancer activity of Artemisia vulgaris L. aqueous extract with cisplatin against A549 lung cancer cell line
Elhawary, S. S. E.-D., Ahmed, H. N., Choucry, M. A., Allam, R. M., Mohamed, O. G., Mahmoud, K., & Elmotayam, A. K. (2026) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-026-05481-5 · Cited by 1
“Quercetin-3-O-glucoside (Hyperoside) [39, 41] Artemisia species are known to be rich in sesquiterpene lactones, and the most recognized compound is artemisinin, which is isolated from A. annua [50].”
A Review on the Properties of Azadirachta indica, Ocimum tenuiflorum and Cymbopogon citratus
Bhagarathi, L. K., Pestano, F., Phillips-Henry, M. Z., Cossiah, C., DaSilva, M. P. N. B., & Singh, M. D. (2021) · International Journal of Scientific Research and Management (IJSRM) · doi:10.18535/ijsrm/v9i10.b01 · Cited by 1
Concise and Free-Metal Access to Lactone-Annelated Pyrrolo[2,1-a]isoquinoline Derivatives via a 1,2-Rearrangement Step
Obydennik, A. Y., Titov, A. А., Listratova, A. V., Borisova, T. N., Rybakov, V. B., Voskressensky, L. G., & Varlamov, A. V. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021085 · Cited by 1
Unveiling the preventive potential of artesin in brain-heart Axis: In-silico insights into Alzheimer's and cardiovascular diseases prevention
Javed, A., Youn, K., Ho, C., & Jun, M. (2025) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2025.110866 · Cited by 2
Artemisinin DNA Base Interaction Studies in Presence of Fe(II): LC/TOF MS Separation of Reaction Products
Oke, K., & Mugweru, A. M. (2021) · Separations · doi:10.3390/separations8090161 · Cited by 1
Testing The Antibacterial Activity of Crude Extracts of Tithonia diversifolia Leaves, Flowers, and Roots in Various Solvent Fraction
Susilowati, I. T., Soetjipto, H., & Hastuti, S. P. (2022) · EduChemia (Jurnal Kimia dan Pendidikan) · doi:10.30870/educhemia.v7i1.12403 · Cited by 1
Assessment of the protective effect of Artemisia herba-alba Asso against Eimeria tenella induced coccidiosis in broilers
Messaï, A., & Redouane-Salah, S. (2021) · Bangladesh Journal of Veterinary Medicine · doi:10.33109/bjvmjj21am1
New Guaianolide Sesquiterpene Lactones and Other Constituents from Pyrethrum pulchrum
Erdenetsogt, U., Nadmid, S., Paetz, C., Dahse, H., Voigt, K., Gotov, C., Boland, W., & Dagvadorj, E. (2021) · Planta Medica · doi:10.1055/a-1554-2866
“STLs possess a wide range of biological activities, including antitumor, antiulcer, antimicrobial, anti-inflammatory, and immunomodulatory properties [5,6].”
Background
IDENTIFICATION OF α-SANTONIN IN ARTEMISIA MARSCHALLIANA SPRENG. COLLECTED IN AZERBAIJAN
(2023) · Plant & fungal research · doi:10.30546/2664-5297.2023.1.22
Additional file 3 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643454
Additional file 2 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Yao, J., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643451
Additional file 4 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643457
Sesquiterpene lactone in Tapinanthus dodoneifolius (Dancer) DC: A phytochemistry according parasite’s host
Karama, I., Ouédraogo, V., Rouamba, A., & Kiendrébeogo, M. (2024) · Journal of Pharmacognosy and Phytochemistry · doi:10.22271/phyto.2024.v13.i3f.14987
SNAKE VENOM ENZYMES NEUTRALIZATION POTENTIAL OF PHYTOCHEMICALS EXTRACTED FROM DATURA ALBA SEEDS
Fatima, S., Tahir, W., Moin, M., Waheed, H., & Khan, H. (2024) · The Journal of Animal and Plant Sciences · doi:10.36899/japs.2024.5.0793
Comparative Analysis of Phytochemicals and Antioxidant Potential of Ethanol Leaf Extracts of Psidium guajava and Syzygium jambos
Santhosh, S. K., & Sarojini, S. (2024) · Journal of Natural Remedies · doi:10.18311/jnr/2024/36164
A Review of the Artemisia Species with Antiviral and Immunomodulatory Potential
BORDEAN, M.-E., MARȚIS, G., UNGUR, R., Anamaria, P. O. P., BORDA, I. M., Carmen, P. O. P., & Marcel, D. U. D. A. (2023) · Hop and Medicinal Plants · doi:10.15835/hamp3112722
Serbian Traditional Spirit Enriched With Yellow Gentian and Saline Wormwood: Volatile Profile and Sensory Traits
Veljović, S. P., Cvetković, D. J., Petrović, M., Luković, M. S., Karabegović, I., Vukosavljević, P. V., & Stevanović, Z. D. (2025) · Flavour and Fragrance Journal · doi:10.1002/ffj.3846
Development and Evaluation of the Antibacterial Properties of an Experimental Herbal Gel Against Cariogenic Bacteria
Sánchez-Tito, M. A., Tay, L. Y., Zea‐Gamboa, F., Cutipa, R. C., Flores‐Gómez, A., Spigno‐Paco, B., Salinas, B. R. M., Calcina, J. E. Z., & Díaz, I. E. C. (2025) · Clinical and Experimental Dental Research · doi:10.1002/cre2.70076
“Particularly, it has been discussed that the mechanism of action of sesqui-terpenoids is associated with the ability to destabilize the microbial cell membrane, due to a lipophilic activity on the cell wall (Ivanescu, Miron, and Corciova 2015; de Moura et al. 2021).”
Hirsutolide isolated from Arctotis fastuosa induces apoptosis and inhibits viability, migration, and invasion of MCF-7 breast cancer cell
Fadil, S. A., Binothman, N., Yonbawi, A. R., Almalki, A. J., Hareeri, R. H., Ashi, A., Alsulaimany, M., Almoghrabi, Y. M., Daghistani, H., Alshangiti, H. H., et al. (2025) · South African Journal of Botany · doi:10.1016/j.sajb.2025.04.005
Hemistepsin A induces apoptosis by modulating the reactive oxygen species-dependent PI3K/Akt signaling pathway in human lung carcinoma A549 cells
Kim, S. Y., Kim, G., & Choi, Y. H. (2025) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.25.044
Additional file 4 of In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms
Băieş, M.-H., Cotuţiu, V.-D., Spînu, M., Mathe, A., Cozma-Petruț, A. P., Bolboacǎ, S. D., Engberg, R. M., Collin, A., & Cozma, V. (2024) · Figshare · doi:10.6084/m9.figshare.26700143
Additional file 2 of In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms
Băieş, M.-H., Cotuţiu, V.-D., Spînu, M., Mathe, A., Cozma-Petruț, A. P., Bolboacǎ, S. D., Engberg, R. M., Collin, A., & Cozma, V. (2024) · Figshare · doi:10.6084/m9.figshare.26700137
Additional file 1 of In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms
Băieş, M.-H., Cotuţiu, V.-D., Spînu, M., Mathe, A., Cozma-Petruț, A. P., Bolboacǎ, S. D., Engberg, R. M., Collin, A., & Cozma, V. (2024) · Figshare · doi:10.6084/m9.figshare.26700134
Additional file 5 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643460
Additional file 7 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643466
Additional file 6 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643463
Additional file 8 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643469
Additional file 3 of In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms
Băieş, M.-H., Cotuţiu, V.-D., Spînu, M., Mathe, A., Cozma-Petruț, A. P., Bolboacǎ, S. D., Engberg, R. M., Collin, A., & Cozma, V. (2024) · Figshare · doi:10.6084/m9.figshare.26700140
Additional file 9 of ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
Cai, L., Gong, Q., Qi, L., Xu, T., Suo, Q., Li, X., Wang, W., Jing, Y., Yang, D., Xu, Z., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19643472
Bioactive Compounds and Amino Acids From Sweet and Southern Wormwood ( Artemisia spp.): Extraction, Characterization, and Antimicrobial Activity Against Opportunistic Pathogens
Kaleja, E., Radenkovs, V., Gāliņa, D., Juhnevica-Radenkova, K., Krasnova, I., & Valdovska, A. (2025) · Journal of Food Biochemistry · doi:10.1155/jfbc/6620031
The effects of Elephantopus mollis Extracts on the Migration, Invasion and Adhesion of Human Cervical Cancer Cells
Long, T. T., Linh, T. P., Phuc, D. M., Thảo, Đ. T. P., & Trinh, N. T. M. (2025) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2025.00828
ETHNOMEDICINAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL INSIGHTS INTO TEPHROSIA PURPUREA (FABACEAE): A COMPREHENSIVE UPDATE
Behera, S. P., Dighe, S. B., Dash, S., & DAS, S. N. (2026) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2026v19i1.57157
Chemical Diversity and Biological Activities of the Artemisia L. Genus Beyond Antimalarial Effects
Karoutzou, O., & Skaltsounis, A. (2026) · Planta Medica · doi:10.1055/a-2805-3483
“Certain artemisinin analogues have reached clinical trials for cancer; artesunate was efficient in combination therapy against breast and non-small-cell lung cancer, while dihydroarte-misinin showed effectiveness in patients with cervix carcinoma [54].”
Effect of Supplemental Lighting and Elicitors on Antioxidant-Related Metabolites of Artemisia annua
Agada, O. O., Onoja, E. A., & Ashiru, T. (2026) · Greener Journal of Agricultural Sciences · doi:10.15580/gjas.2026.1.030226031
“…is not equally as valuable since there is evidence that other compounds found in A. annua work synergistically with artemisinin for enhanced efficacy against malaria (Ferreira et al., 2010) and cancer (Ivanescu et al., 2015), making it pertinent to find means of enhancing in-plant production.”
Exploration of traditional medicines as source of bioactive compounds : from ethnobotany to pharmacomodulation
Ortíz, S. (2019) · doi:10.70675/57d4e95czd255z4610z858fza39d5c488623
Chicory-derived lactucins: research progress on its biological activity and extraction methods
Guo, X., Cheng, Y., Qiao, Z., Hu, Z., Xu, J., Song, W., Qi, J., Zeng, X., Yuan, Y., Ling, L., et al. (2026) · Food Chemistry · doi:10.1016/j.foodchem.2026.149210
Artemiannua A, new sesquiterpenoid from the aerial part of artemisia annua with anti-inflammatory activity
Nagdy, M. M., Meng, C., Yuan, H., Ju, F., Hallouty, S. E., Zeng, L., Meng, F., Dong, Z., Liao, Z., & Chen, M. (2026) · Natural Product Research · doi:10.1080/14786419.2026.2658145
Phytochemical Composition and Biological Properties of Plants of the Genus Parthenium
Jiménez, M. Á. A., Medina-Morales, M. Á., Silva‐Belmares, S. Y., Ríos-González, L. J., & Rivera, C. A. S. (2026) · World sustainability series · doi:10.1007/978-3-032-10314-7_26
Functional transcriptomic analysis and drought-induced regulation of secondary metabolism in Artemisia ludoviciana Nutt.
Fernández-Cortés, J. M., Iglesias, D., de Donato, M., Balderas-Robles, A. A., Angulo‐Bejarano, P. I., & Sharma, A. (2026) · BMC Plant Biology · doi:10.1186/s12870-026-08770-w
“Sesquiterpene lactones (SL) are another important group of bioactive compounds characteristic of A. ludoviciana and other species of the Asteraceae family [59].”
MS/MS-based molecular networking for exploring the chemical diversity of Chiliadenus montanus (Vahl.) brullo and Chiliadenus candicans (Delile) brullo and their anti-ulcer potential via modulation of Nrf2/ICAM-1 in rats
Shaheen, A. M., Abdel-Sattar, E. A., El-Kashoury, E.-S. A., Tawfik, W. A., Mohamed, T. A., Hegazi, N. M., Salama, A. A. A., & Hegazy, M. F. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.121954
Phytochemical characterization and bioactivity evaluation of Artemisia abyssinica methanolic extract as a baseline for bioresource exploration
Aldarhami, A., Alderhami, S. A., Harzali, H., Bazaid, A. S., Alzahrani, Z. I., Eladawy, H. A., Abdullah, N. H., Saeedi, N. H., Abdelshafeek, K. A., & Elhenawy, A. A. (2026) · Bioresources and Bioprocessing · doi:10.1186/s40643-026-01103-7
“…in Arte-misia , including essential oils, sesquiterpene lactones, flavonoids, coumarins, artemisinin, arglabin, and other phenolics (Preedy 2016, Ivanescu et al. 2015, Crozier et al. 2006, Stefanachi et al. 2018, Cui and Su 2009, Mehdi-khani et al. 2025, Clifford 2000, Zhang et al. 2026).”
In-vivo anthelmintic potential of Artemisia maritima and its effects on haematological parameters in sheep of Kashmir
Wani, T., Akhoon, Z. A., Wani, Z. A., John, M. A., Hussain, S. A., Tramboo, S. R., Beigh, Y. A., Shah, S. A., & Kawoosa, M. S. (2026) · Veterinary Parasitology Regional Studies and Reports · doi:10.1016/j.vprsr.2026.101562
Biological Activity of Artemisia mexicana: Antimalarial, Immunomodulatory, and Antioxidant Effects in Experimental Malaria
López-Padilla, M. S., Cervantes-Candelas, L. A., Aguilar-Castro, J., Nolasco-Pérez, T. D. J., Buendía-González, F. O., Ávila-Acevedo, J. G., Estrella-Parra, E. A., & Legorreta‐Herrera, M. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27177637
“Several Several compounds, including sesquiterpene lactones and volatile terpenoids, are chemically unstable and may undergo degradation during extraction, purification, or storage [46].”
Korean Artemisia species: phylogenomic authentication, ethnopharmacology, and commercial applications
Amin, A., Abbas, K., & de Oliveira, M. S. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1873437

Authors: Ivanescu, B., Miron, A., & Corciova, A.
Affiliations: Department of Pharmaceutical Botany, Faculty of Pharmacy, University of Medicine and Pharmacy “Grigore T. Popa”, 16 Universitatii Street, 700150 Iasi, Romania
Grigore T. Popa University of Medicine and Pharmacy (RO)
Department of Drug Analysis, Faculty of Pharmacy, University of Medicine and Pharmacy “Grigore T. Popa”, 16 Universitatii Street, 700150 Iasi, Romania
ORCID: Miron, Anca
Venue: Journal of Analytical Methods in Chemistry
Publisher: Wiley
Published: 2015
Volume: 2015
Pages: 1-21
ISSN: 2090-8865 (ISSN-L)
2090-8873
DOI: 10.1155/2015/247685
PMC: PMC4606394
OpenAlex: W1950362769
Cited by: 201
References: 156
Citations by year: 2026: 18 · 2025: 20 · 2024: 34 · 2023: 19 · 2022: 34 · 2021: 21 · 2020: 19 · 2019: 11 · 2018: 10 · 2017: 11 · 2016: 4
FWCI: 0.81
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (unspecified)
Locations: Journal of Analytical Methods in Chemistry (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: European Social Fund (POSDRU/159/1.5/S/136893)
Topics: Physical Sciences › Chemistry › Organic Chemistry › Sesquiterpenes and Asteraceae Studies
Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
Keywords: sesquiterpene lactones, Artemisia, eudesmanolides, guaianolides, germacranolides, α-methylene-γ-lactones, biological activity, natural product identification, quantification, extraction and separation, thermolabile compounds, Michael addition

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks