The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.
Complementary and Alternative Therapies for Autism Spectrum Disorder
Open accessAbstract
Background. Complementary and alternative medicine (CAM) represents a popular therapeutic option for patients with autism spectrum disorder (ASD). Unfortunately, there is a paucity of data regarding the efficacy of CAM in ASD. The aim of the present systematic review is to investigate trials of CAM in ASD. Material and Methods. We searched the following databases: MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, CINAHL, Psychology and Behavioral Sciences Collection, Agricola, and Food Science Source. Results. Our literature search identified 2687 clinical publications. After the title/abstract screening, 139 publications were obtained for detailed evaluation. After detailed evaluation 67 studies were included, from hand search of references we retrieved 13 additional studies for a total of 80. Conclusion. There is no conclusive evidence supporting the efficacy of CAM therapies in ASD. Promising results are reported for music therapy, sensory integration therapy, acupuncture, and massage.
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“Neuroprotective action of carnosine has been reported, and beneficial effects on behavior of subjects with ASD have been observed in some studies, however, they were not confirmed by other studies. At present, there is insufficient support for efficacy of carnosine in ASD [60].”
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Metadata
- Authors
- Brondino, N., Fusar-Poli, L., Rocchetti, M., Provenzani, U., Barale, F., & Politi, P.
- Affiliations
- University of Pavia (IT)
- Department of Brain and Behavioral Sciences, Section of Psychiatry, University of Pavia, Via Bassi 21, 27100 Pavia, Italy
- Corresponding author
- Brondino, Natascia
- Venue
- Evidence-Based Complementary and Alternative Medicine
- Publisher
- Wiley
- Published
- 2015
- Volume
- 2015
- Pages
- 1-31
- ISSN
- 1741-427X (ISSN-L)
- 1741-4288
- PMC
- PMC4439475
- OpenAlex
- W1518643840
- Cited by
- 116
- References
- 142
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 13 · 2023: 8 · 2022: 20 · 2021: 10 · 2020: 15 · 2019: 13 · 2018: 7 · 2017: 4 · 2016: 5 · 2015: 1
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Evidence-based Complementary and Alternative Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, complementary and alternative medicine, music therapy, sensory integration therapy, acupuncture, massage, clinical trials
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