Complementary and Alternative Therapies for Autism Spectrum Disorder

Pharmacological interventions for somatoform disorders in adults

Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,369

Complementary and Alternative Medicine Use Among Adults and Children: United States, 2007

Barnes, P. M., Bloom, B. E., & Nahin, R. L. (2008) · PsycEXTRA Dataset · doi:10.1037/e623942009-001 · Cited by 3,144

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D., & Rubin, R. A. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-22 · Cited by 1,076

Prevalence of autism-spectrum conditions: UK school-based population study

Baron-Cohen, S., Scott, F. J., Allison, C., Williams, J., Bolton, P., Matthews, F. E., & Brayne, C. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.059345 · Cited by 918

Internet survey of treatments used by parents of children with autism.

Green, V. A., Pituch, K. A., Itchon, J., Choi, A., O’Reilly, M., & Sigafoos, J. (2006) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2004.12.002 · Cited by 617

Hyperbaric oxygen: its uses, mechanisms of action and outcomes

Gill, A. L., & Bell, C. N. A. (2004) · QJM · doi:10.1093/qjmed/hch074 · Cited by 515

Gastrointestinal abnormalities in children with autistic disorder

Horváth, K., Papadimitriou, J. C., Rabsztyn, A., Drachenberg, C. B., & Tildón, J. T. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70052-1 · Cited by 489

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.61 · Cited by 480

GABA system dysfunction in autism and related disorders: From synapse to symptoms

Coghlan, S., Horder, J., Inkster, B., Méndez, M. A., Murphy, D., & Nutt, D. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.07.005 · Cited by 459

Music therapy for people with autism spectrum disorder

Geretsegger, M., Elefant, C., Mössler, K. A., & Gold, C. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004381.pub3 · Cited by 445

The interplay between sensory processing abnormalities, intolerance of uncertainty, anxiety and restricted and repetitive behaviours in autism spectrum disorder

Wigham, S., Rodgers, J., South, M., McConachie, H., & Freeston, M. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2248-x · Cited by 373 · cited 1×

Ketogenic diet and other dietary treatments for epilepsy

Martin-McGill, K. J., Jackson, C. F., Levy, R. G., & Cooper, P. N. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001903.pub3 · Cited by 372

The Effects of Improvisational Music Therapy on Joint Attention Behaviors in Autistic Children: A Randomized Controlled Study

Kim, J., Wigram, T., & Gold, C. (2008) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0566-6 · Cited by 371

Effectiveness of Sensory Integration Interventions in Children With Autism Spectrum Disorders: A Pilot Study

Pfeiffer, B., Koenig, K. P., Kinnealey, M., Sheppard, M., & Henderson, L. (2011) · American Journal of Occupational Therapy · doi:10.5014/ajot.2011.09205 · Cited by 369

Omega-3 fatty acids suppleMentation in children with autism: A double-blind randomized, placebo-controlled pilot study

Amminger, G. P., Berger, G. E., Schäfer, M. R., Klier, C., Friedrich, M. H., & Feucht, M. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.007 · Cited by 355

Yoga Asana Sessions Increase Brain GABA Levels: A Pilot Study

Streeter, C. C., Jensen, J. E., Perlmutter, R., Cabral, H., Tian, H., Terhune, D. B., Ciraulo, D. A., & Renshaw, P. F. (2007) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2007.6338 · Cited by 343

A Randomised, Controlled Study of Dietary Intervention in Autistic Syndromes

Knivsberg, A. M., Reichelt, K. L., Høien, T., & Nødland, M. (2002) · Nutritional Neuroscience · doi:10.1080/10284150290028945 · Cited by 315

Ketogenic diet and other dietary treatments for epilepsy

Levy, R. G., Cooper, P. N., Giri, P., & Weston, J. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001903.pub2 · Cited by 313

The Gluten-Free, Casein-Free Diet In Autism: Results of A Preliminary Double Blind Clinical Trial

Elder, J. H., Shankar, M. N., Shuster, J. J., Theriaque, D. W., Burns, S., & Sherrill, L. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0079-0 · Cited by 312

Altered brain-gut axis in autism: comorbidity or causative mechanisms

Mayer, E. A., Padua, D., & Tillisch, K. (2014) · BioEssays · doi:10.1002/bies.201400075 · Cited by 304

Use of Complementary and Alternative Medicine among Children Diagnosed with Autism Spectrum Disorder

Hanson, E. M., Kalish, L. A., Bunce, E., Curtis, C. M., McDaniel, S., Ware, J., & Petry, J. J. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0192-0 · Cited by 302

Effect of a vitamin/mineral supplement on children and adults with autism

Adams, J. B., AUDHYA, T. K., McDonough-Means, S. I., Rubin, R. A., Quig, D. W., Geis, E., Gehn, E., Loresto, M., Mitchell, J., Atwood, S., et al. (2011) · BMC Pediatrics · doi:10.1186/1471-2431-11-111 · Cited by 297

Quercetin, a Flavonoid Antioxidant, Prevents and Protects against Ethanol-Induced Oxidative Stress in Mouse Liver

Molina, M. F., Sánchez-Reus, I., Peinado, I. I., & Benedı́, J. (2003) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.26.1398 · Cited by 297

Music and Early Language Acquisition

Brandt, A., Gebrian, M., & Slevc, L. R. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00327 · Cited by 289

Application of a ketogenic diet in children with autistic behavior: Pilot study

Evangeliou, A., Vlachonikolis, I., Mihailidou, H., Spilioti, M., Skarpalezou, A., Makaronas, N., Prokopiou, A., Christodoulou, P., Liapi-Adamidou, G., Helidonis, E., et al. (2003) · Journal of Child Neurology · doi:10.1177/08830738030180020501 · Cited by 279

The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders

Whiteley, P., Haracopos, D., Knivsberg, A.-M., Reichelt, K. L., Parlar, S., Jacobsen, J., Seim, A., Pedersen, L., Schondel, M., & Shattock, P. (2010) · Nutritional Neuroscience · doi:10.1179/147683010x12611460763922 · Cited by 266

Calming Effects of Deep Touch Pressure in Patients with Autistic Disorder, College Students, and Animals

Grandin, T. (1992) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.1992.2.63 · Cited by 263

Musically Adapted Social Stories to Modify Behaviors in Students with Autism: Four Case Studies

Brownell, M. D. (2002) · Journal of Music Therapy · doi:10.1093/jmt/39.2.117 · Cited by 261

An Open-Label Pilot Study of a Formulation Containing the Anti-Inflammatory Flavonoid Luteolin and Its Effects on Behavior in Children With Autism Spectrum Disorders

Taliou, A., Zintzaras, E., Lykouras, L., & Francis, K. (2013) · Clinical Therapeutics · doi:10.1016/j.clinthera.2013.04.006 · Cited by 239

Essential fatty acids and the brain: From infancy to aging

Yehuda, S., Rabinovitz, S., & Mostofsky, D. I. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.09.013 · Cited by 227

Patterns of Complementary and Alternative Medical Therapy Use in Children Diagnosed with Autism Spectrum Disorders

Wong, H. H. L., & Smith, R. G. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0131-0 · Cited by 227

Mirroring in Dance/Movement Therapy: Potential mechanisms behind empathy enhancement

McGarry, L. M., & Russo, F. (2011) · The Arts in Psychotherapy · doi:10.1016/j.aip.2011.04.005 · Cited by 222

Double-Blind, Placebo-Controlled Study of L-Carnosine Supplementation in Children With Autistic Spectrum Disorders

Chez, M. G., Buchanan, C. P., Aimonovitch, M. C., Becker, M., Schaefer, K., Black, C., & Komen, J. (2002) · Journal of Child Neurology · doi:10.1177/08830738020170111501 · Cited by 221

Functional Foods and Nutraceuticals in the Primary Prevention of Cardiovascular Diseases

Alissa, E. M., & Ferns, G. A. (2012) · Journal of Nutrition and Metabolism · doi:10.1155/2012/569486 · Cited by 221

Complementary and Alternative Medicine Treatments for Children with Autism Spectrum Disorders

Levy, S. E., & Hyman, S. L. (2008) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2008.06.004 · Cited by 218

Use of Complementary and Alternative Medicine Among Children Recently Diagnosed with Autistic Spectrum Disorder

Levy, S. E., Mandell, D. S., Merhar, S. L., Ittenbach, R. F., & Pinto‐Martin, J. A. (2003) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200312000-00003 · Cited by 193

The level of arabinitol in autistic children after probiotic therapy

Kałużna-Czaplińska, J., & Błaszczyk, S. (2012) · Nutrition · doi:10.1016/j.nut.2011.08.002 · Cited by 189

The Effects of Occupational Therapy With Sensory Integration Emphasis on Preschool-Age Children With Autism

Case‐Smith, J., & Bryan, T. (1999) · American Journal of Occupational Therapy · doi:10.5014/ajot.53.5.489 · Cited by 184

A preliminary trial of ascorbic acid as supplemental therapy for autism

Dolske, M. C., Spollen, J., McKay, S., Lancashire, E., & Tolbert, L. (1993) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(93)90058-z · Cited by 168

Mercury Exposure: Evaluation and Intervention

Risher, J. F., & Amler, S. N. (2005) · NeuroToxicology · doi:10.1016/j.neuro.2005.05.004 · Cited by 168

Brief report: theatre as therapy for children with autism spectrum disorder

Corbett, B. A., Gunther, J. R., Comins, D., Price, J., Ryan, N., Simon, D., Schupp, C. W., & Rios, T. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1064-1 · Cited by 160

Brief Report: Improvements in the Behavior of Children with Autism Following Massage Therapy

Escalona, A., Field, T. M., Singer-Strunck, R., Cullen, C., & Hartshorn, K. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1012273110194 · Cited by 160

A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder

Bent, S., Bertoglio, K., Ashwood, P., Bostrom, A., & Hendren, R. L. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1078-8 · Cited by 156

Symptom Profile of ADHD in Youth With High-Functioning Autism Spectrum Disorder: A Comparative Study in Psychiatrically Referred Populations

Joshi, G., Faraone, S. V., Wozniak, J., Tarko, L., Fried, R., Galdo, M., Furtak, S. L., & Biederman, J. (2017) · Journal of Attention Disorders · doi:10.1177/1087054714543368 · Cited by 155

Brief report: A pilot study of auditory integration training in autism

Rimland, B., & Edelson, S. M. (1995) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02178168 · Cited by 154

Effect of "Developmental Speech and Language Training Through Music" on Speech Production in Children with Autism Spectrum Disorders

Lim, H. A. (2010) · Journal of Music Therapy · doi:10.1093/jmt/47.1.2 · Cited by 154

Combined vitamin B6-magnesium treatment in autism spectrum disorder

Nye, C., & Brice, A. E. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003497.pub2 · Cited by 153

Dietary intake and parents’ perception of mealtime behaviors in preschool-age children with autism spectrum disorder and in typically developing children

Lockner, D. W., Crowe, T. K., & Skipper, B. J. (2008) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2008.05.003 · Cited by 152

A Chinese Mind-Body Exercise Improves Self-Control of Children with Autism: A Randomized Controlled Trial

Chan, A. S.-Y., Sze, S. L., Siu, N. Y.-F., Lau, E. M., & Cheung, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068184 · Cited by 151

Effects of relational music therapy on communication of children with autism: a randomized controlled study

Gattino, G., Riesgo, R. D. S., Longo, D., Leite, J. C. L., & Faccini, L. S. (2011) · Nordic Journal of Music Therapy · doi:10.1080/08098131.2011.566933 · Cited by 150

Music Therapy for the Autistic Child

Alvin, J., & Warwick, A. (1992) · doi:10.1093/oso/9780198162766.001.0001 · Cited by 147

Efficacy of the Get Ready to Learn Yoga Program Among Children With Autism Spectrum Disorders: A Pretest–Posttest Control Group Design

Koenig, K. P., Buckley-Reen, A., & Garg, S. (2012) · American Journal of Occupational Therapy · doi:10.5014/ajot.2012.004390 · Cited by 146

Effects of Classroom Animal-Assisted Activities on Social Functioning in Children with Autism Spectrum Disorder

O’Haire, M. E., McKenzie, S. J., McCune, S., & Slaughter, V. P. (2013) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2013.0165 · Cited by 145

A Gluten-Free Diet as an Intervention for Autism and Associated Spectrum Disorders: Preliminary Findings

Whiteley, P., Rodgers, J., Savery, D., & Shattock, P. (1999) · Autism · doi:10.1177/1362361399003001005 · Cited by 140

Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)

AL-Ayadhi, L. Y., & Elamin, N. E. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/602834 · Cited by 140

Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)

James, S., Montgomery, P., & Williams, K. J. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007992.pub2 · Cited by 138

Effect of Long-Term Interactive Music Therapy on Behavior Profile and Musical Skills in Young Adults with Severe Autism

Boso, M., Emanuele, E., Minazzi, V., Abbamonte, M., & Politi, P. (2007) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2006.6334 · Cited by 138

Auditory integration training and other sound therapies for autism spectrum disorders (ASD)

Sinha, Y., Silove, N., Hayen, A. D., & Williams, K. J. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003681.pub3 · Cited by 137

The long-term effects of auditory training on children with autism

Bettison, S. (1996) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172480 · Cited by 137

Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury

Bennett, M. H., Trytko, B., & Jonker, B. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004609.pub3 · Cited by 137

Complementary and alternative medicine use in a large pediatric autism sample

Perrin, J. M., Coury, D. L., Hyman, S. L., Cole, L., Reynolds, A. M., & Clemons, T. (2012) · PEDIATRICS · doi:10.1542/peds.2012-0900e · Cited by 135

Advances in the Research of Melatonin in Autism Spectrum Disorders: Literature Review and New Perspectives

Tordjman, S., Najjar, I., Bellissant, E., Anderson, G., Barburoth, M., Cohen, D., Jaafari, N., Schischmanoff, O., Fagard, R., Lagdas, E., et al. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141020508 · Cited by 132

Role of polyunsaturated fatty acids in the management of Egyptian children with autism

Meguid, N. A., Atta, H. M., Gouda, A. S., & Khalil, R. O. (2008) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2008.05.013 · Cited by 128

Internet-Based, Randomized, Controlled Trial of Omega-3 Fatty Acids for Hyperactivity in Autism

Bent, S., Hendren, R. L., Zandi, T., Law, K., Choi, J., Widjaja, F., Kalb, L. G., Nestle, J., & Law, P. A. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2014.01.018 · Cited by 127

Markers of celiac disease and gluten sensitivity in children with autism

Lau, N. M., Green, P. H. R., Taylor, A. K., Hellberg, D., Ajamian, M., Tan, C. Z., Kosofsky, B. E., Higgins, J. J., Rajadhyaksha, A. M., & Alaedini, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066155 · Cited by 124

Fronto‐Temporal Connectivity is Preserved During Sung but Not Spoken Word Listening, Across the Autism Spectrum

Sharda, M., Midha, R., Malik, S., Mukerji, S., & Singh, N. C. (2014) · Autism Research · doi:10.1002/aur.1437 · Cited by 121

The Effects of Music Therapy Incorporated with Applied Behavior Analysis Verbal Behavior Approach for Children with Autism Spectrum Disorders

Lim, H. A., & Draper, E. S. (2011) · Journal of Music Therapy · doi:10.1093/jmt/48.4.532 · Cited by 120

The Effects of Signed and Spoken Words Taught with Music on Sign and Speech Imitation by Children with Autism

Buday, E. M. (1995) · Journal of Music Therapy · doi:10.1093/jmt/32.3.189 · Cited by 115

Pilot Study of the Effect of Methyl B12 Treatment on Behavioral and Biomarker Measures in Children with Autism

Bertoglio, K., James, S. J., Deprey, L., Brule, N., & Hendren, R. L. (2010) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2009.0177 · Cited by 113

Relaxation Response–Based Yoga Improves Functioning in Young Children with Autism: A Pilot Study

Rosenblatt, L. E., Gorantla, S., Torres, J. A., Yarmush, R. S., Rao, S., Park, E. R., Denninger, J. W., Benson, H., Fricchione, G. L., Bernstein, B., et al. (2011) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2010.0834 · Cited by 113

Prospective trial of equine-assisted activities in autism spectrum disorder.

Kern, J. K., Fletcher, C. L., Garver, C. R., Mehta, J. A., Grannemann, B. D., Knox, K. R., Richardson, T. A., & Trivedi, M. H. (2011) · PubMed · Cited by 111

High-Dose Pyridoxine and Magnesium Administration in Children with Autistic Disorder: An Absence of Salutary Effects in a Double-Blind, Placebo-Controlled Study

Findling, R. L., Maxwell, K., Scotese-Wojtila, L., Huang, J., Yamashita, T. S., & Wiznitzer, M. (1997) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1025861522935 · Cited by 110

The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study

Rossignol, D. A., Rossignol, L. W., James, S. J., Melnyk, S., & Mumper, E. A. (2007) · BMC Pediatrics · doi:10.1186/1471-2431-7-36 · Cited by 108

Interactions between carnosine and zinc and copper: implications for neuromodulation and neuroprotection.

Trombley, P. Q., Horning, M. S., & Blakemore, L. J. (2000) · PubMed · Cited by 104

Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial

Rossignol, D. A., Rossignol, L. W., Smith, S. A., Schneider, C., Logerquist, S., Usman, A., Neubrander, J., Madren, E. M., Hintz, G., Grushkin, B., et al. (2009) · BMC Pediatrics · doi:10.1186/1471-2431-9-21 · Cited by 97

Carnosine protects against permanent cerebral ischemia in histidine decarboxylase knockout mice by reducing glutamate excitotoxicity

Shen, Y., He, P., Fan, Y.-Y., Zhang, J.-X., Yan, H.-J., Hu, W.-W., Ohtsu, H., & Chen, Z. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.12.021 · Cited by 95

Dietary Docosahexaenoic Acid Supplementation in Children With Autism

Voigt, R. G., Mellon, M. W., Katusic, S. K., Weaver, A. L., Matern, D., Mellon, B., Jensen, C. L., & Barbaresi, W. J. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000260 · Cited by 94

Effects of Gluten Free / Casein Free Diet in Young Children with Autism: A Pilot Study

Johnson, C. R., Handen, B. L., Zimmer, M., Sacco, K. A., & Turner, K. S. (2010) · Journal of Developmental and Physical Disabilities · doi:10.1007/s10882-010-9217-x · Cited by 92

A Sensory Integration Therapy Program on Sensory Problems for Children with Autism

Fazlıoğlu, Y., & Baran, G. (2008) · Perceptual and Motor Skills · doi:10.2466/pms.106.2.415-422 · Cited by 92

Qigong Massage Treatment for Sensory and Self-Regulation Problems in Young Children With Autism: A Randomized Controlled Trial

Silva, L. M. T., Schalock, M. D., Ayres, R., Bunse, C., & Budden, S. S. (2009) · American Journal of Occupational Therapy · doi:10.5014/ajot.63.4.423 · Cited by 88

Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status

Frye, R. E., Melnyk, S., Fuchs, G. J., Reid, T., Jernigan, S., Pavliv, O., Hubanks, A., Gaylor, D. W., Walters, L., & James, S. J. (2013) · Autism Research and Treatment · doi:10.1155/2013/609705 · Cited by 87

Autism spectrum disorders and allergy: observation from a pediatric allergy/immunology clinic

Jyonouchi, H. (2010) · Expert Review of Clinical Immunology · doi:10.1586/eci.10.18 · Cited by 84

Music as a therapy: Role in psychiatry

Solanki, M. S., Zafar, M., & Rastogi, R. (2013) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2012.12.001 · Cited by 84

Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A - Medical results

Adams, J. B., Baral, M., Geis, E., Mitchell, J., Ingram, J., Hensley, A., Zappia, I., Newmark, S. C., Gehn, E., Rubin, R. A., et al. (2009) · BMC Clinical Pharmacology · doi:10.1186/1472-6904-9-16 · Cited by 82

Behavioral Effects of Omega-3 Fatty Acid Supplementation in Young Adults with Severe Autism: An Open Label Study

Politi, P., Cena, H., Comelli, M., Marrone, G., Allegri, C., Emanuele, E., & Nemi, S. U. D. (2008) · Archives of Medical Research · doi:10.1016/j.arcmed.2008.06.005 · Cited by 81

A Systematic Review and Meta-Analysis ofGinkgo bilobain Neuropsychiatric Disorders: From Ancient Tradition to Modern-Day Medicine

Brondino, N., Silvestri, A. D., Re, S., Lanati, N., Thiemann, P., Verna, A., Emanuele, E., & Politi, P. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/915691 · Cited by 76

Brief Report: The Smiles of a Child with Autism Spectrum Disorder During an Animal-assisted Activity May Facilitate Social Positive Behaviors—Quantitative Analysis with Smile-detecting Interface

Funahashi, A., Gruebler, A., Aoki, T., Kadone, H., & Suzuki, K. (2013) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-013-1898-4 · Cited by 75

A review of evidence-based early intervention for behavioural problems in children with autism spectrum disorder: the core components of effective programs, child-focused interventions and comprehensive treatment models

Tonge, B. J., Bull, K., Brereton, A., & Wilson, R. (2014) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000043 · Cited by 75

Antibodies against Food Antigens in Patients with Autistic Spectrum Disorders

de Magistris, L., Picardi, A., Siniscalco, D., Riccio, M. P., Sapone, A., Cariello, R., Abbadessa, S., Medici, N., Lammers, K. M., Schiraldi, C., et al. (2013) · BioMed Research International · doi:10.1155/2013/729349 · Cited by 73

Chelation treatment for autism spectrum disorders: A systematic review

Davis, T. N., O’Reilly, M. F., Kang, S., Lang, R. B., Rispoli, M. J., Sigafoos, J., Lancioni, G. E., Copeland, D., Attai, S. L., & Mulloy, A. M. (2012) · Research in Autism · doi:10.1016/j.rasd.2012.06.005 · Cited by 73

Metabolic effects of sapropterin treatment in autism spectrum disorder: a preliminary study

Frye, R. E., DeLaTorre, R., Taylor, H., Slattery, J. M., Melnyk, S., Chowdhury, N., & James, S. J. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.14 · Cited by 70

Effects of Thai Traditional Massage on Autistic Children's Behavior

Piravej, K., Tangtrongchitr, P., Chandarasiri, P., Paothong, L., & Sukprasong, S. (2009) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2009.0258 · Cited by 67

Family-Centered Music Therapy in the Home Environment: Promoting Interpersonal Engagement between Children with Autism Spectrum Disorder and Their Parents

Thompson, G. A. (2012) · Music Therapy Perspectives · doi:10.1093/mtp/30.2.109 · Cited by 67

A Double-Blind Placebo Controlled Trial of Ginkgo biloba Added to Risperidone in Patients with Autistic Disorders

Hasanzadeh, E., Mohammadi, M.-R., Ghanizadeh, A. J., Rezazadeh, S., Tabrizi, M. H., Rezaei, F., & Akhondzadeh, S. (2012) · Child Psychiatry & Human Development · doi:10.1007/s10578-012-0292-3 · Cited by 66

Dietary intervention in autistic syndromes.

Knivsberg, A. M., Wiig, K., Lind, G., Nødland, M., & Reichelt, K. L. (1990) · Cited by 66

Improvement in Sensory Impairment and Social Interaction in Young Children with Autism Following Treatment with an Original Qigong Massage Methodology

Silva, L. M. T., Cignolini, A., Warren, R., Budden, S. S., & Skowron-Gooch, A. (2007) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x07004916 · Cited by 64

National Center for Complementary and Alternative Medicine Website

Fan, K. (2005) · Europe PMC (PubMed Central) · Cited by 64

Tetrahydrobiopterin as a Treatment for Autism Spectrum Disorders: A Double-Blind, Placebo-Controlled Trial

Klaiman, C., Huffman, L. C., Masaki, L., & Elliott, G. R. (2013) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2012.0127 · Cited by 63

Effect of a combined dance/movement and music therapy on young adults diagnosed with severe autism

Mateos-Moreno, D., & Doña, L. A. (2013) · The Arts in Psychotherapy · doi:10.1016/j.aip.2013.09.004 · Cited by 63

Double-Blind, Placebo-Controlled Trial of Risperidone Plus Amantadine in Children With Autism

Mohammadi, M.-R., Yadegari, N., Hassanzadeh, E., Farokhnia, M., Yekehtaz, H., Mirshafiee, O., & Akhondzadeh, S. (2013) · Clinical Neuropharmacology · doi:10.1097/wnf.0b013e3182a9339d · Cited by 62

Nutritional status survey of children with autism and typically developing children aged 4–6 years in Heilongjiang Province, China

Sun, C., Xia, W. T., Zhao, Y., Li, N., Zhao, D., & Wu, L. (2013) · Journal of Nutritional Science · doi:10.1017/jns.2013.9 · Cited by 61

Restriction and Elimination Diets in ADHD Treatment

Nigg, J. T., & Holton, K. (2014) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2014.05.010 · Cited by 60

Joint Attention Responses of Children with Autism Spectrum Disorder to Simple versus Complex Music

Kalas, A. (2012) · Journal of Music Therapy · doi:10.1093/jmt/49.4.430 · Cited by 58

Effect of camel milk on thymus and activation-regulated chemokine in autistic children: double-blind study

Bashir, S., & AL-Ayadhi, L. Y. (2013) · Pediatric Research · doi:10.1038/pr.2013.248 · Cited by 57

Massage Therapy for Children With Autism Spectrum Disorders

Lee, M. S., Kim, J., & Ernst, E. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09r05848whi · Cited by 56

Decrease in 6R-5,6,7,8-tetrahydrobiopterin content in cerebrospinal fluid of autistic patients

Tani, Y., Fernell, E., Watanabe, Y., Kanai, T., & Långström, B. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90586-x · Cited by 54

Randomized trial of hyperbaric oxygen therapy for children with autism

Granpeesheh, D., Tarbox, J., Dixon, D. R., Wilke, A. E., Allen, M. S., & Bradstreet, J. J. (2009) · Research in Autism · doi:10.1016/j.rasd.2009.09.014 · Cited by 54

Brief report: Lack of response in an autistic population to a low dose clinical trial of pyridoxine plus magnesium

Tolbert, L. C., Haigler, T., Waits, M. M., & Dennis, T. A. (1993) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01066428 · Cited by 53

Dietary status and impact of risperidone on nutritional balance in children with autism: A pilot study

Lindsay, R. L., Eugene Arnold, L., Aman, M. G., Vitiello, B., Posey, D. J., McDougle, C. J., Scahill, L., Pachler, M., McCracken, J. T., Tierney, E., et al. (2006) · Journal of Intellectual & Developmental Disability · doi:10.1080/13668250601006924 · Cited by 52

Peptides’ role in autism with emphasis on exorphins

Reichelt, K. L., Tveiten, D., Knivsberg, A. M., & Brønstad, G. (2012) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v23i0.18958 · Cited by 52

Digestive Enzyme Supplementation for Autism Spectrum Disorders: A Double-Blind Randomized Controlled Trial

Munasinghe, S. A., Oliff, C., Finn, J., & Wray, J. A. (2010) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-0974-2 · Cited by 51

Scalp Acupuncture Effect on Language Development in Children with Autism: A Pilot Study

Allam, H., Hafez, N., & Helmy, G. (2008) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2007.0508 · Cited by 51

The Pathogenesis of Autism

Watts, T. J. (2008) · Clinical Medicine Insights Pathology · doi:10.4137/cpath.s1143 · Cited by 49

Effects of vibroacoustic music on challenging behaviors in individuals with autism and developmental disabilities

Lundqvist, L., Andersson, G. W., & Viding, J. (2008) · Research in Autism · doi:10.1016/j.rasd.2008.08.005 · Cited by 48

Tetrahydrobiopterin in the Treatment of Children With Autistic Disorder

Danfors, T., von Knorring, A.-L., Hartvig, P., Långström, B., Moulder, R., Strömberg, B., Torstenson, R., Oxelgren, U. W., Watanabe, Y., & Eeg‐Olofsson, O. (2005) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000177667.35016.e9 · Cited by 47

Potential Role of Brain-Derived Neurotrophic Factor in Omega–3 Fatty Acid Supplementation to Prevent Posttraumatic Distress after Accidental Injury: An Open-Label Pilot Study

Matsuoka, Y., Nishi, D., Yonemoto, N., Hamazaki, K., Hamazaki, T., & Hashimoto, K. (2011) · Psychotherapy and Psychosomatics · doi:10.1159/000322980 · Cited by 45

A clinical trial of combined anti-androgen and anti-heavy metal therapy in autistic disorders.

Geier, D. A., & Geier, M. R. (2006) · PubMed · Cited by 44

Auditory Integration Training

Edelson, S. M., Arin, D., Bauman, M. L., Lukas, S. E., Rudy, J. H., Sholar, M. B., & Rimland, B. (1999) · Focus on Autism and Other Developmental Disabilities · doi:10.1177/108835769901400202 · Cited by 44

Randomized Controlled Trial of Acupuncture Versus Sham Acupuncture in Autism Spectrum Disorder

Wong, V. C., & Sun, J.-G. (2010) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2007.0768 · Cited by 41

The Efficacy of Auditory Integration Training

Zollweg, W., Palm, D., & Vance, V. (1997) · American Journal of Audiology · doi:10.1044/1059-0889.0603.39 · Cited by 41

Effects of music-based social stories on comprehension and generalization of social skills in children with autism spectrum disorders: A randomized effectiveness study

Schwartzberg, E. T., & Silverman, M. J. (2013) · The Arts in Psychotherapy · doi:10.1016/j.aip.2013.06.001 · Cited by 39

Pyridoxine treatment in a subgroup of children with pervasive developmental disorders

Kuriyama, S., Kamiyama, M., Watanabe, M., Tamahashi, S., Muraguchi, I., Watanabe, T., Hozawa, A., Ohkubo, T., Nishino, Y., Tsubono, Y., et al. (2002) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162201232071 · Cited by 35

Hyperbaric oxygen in the treatment of childhood autism: a randomised controlled trial.

Sampanthavivat, M., Singkhwa, W., Chaiyakul, T., Karoonyawanich, S., & Ajpru, H. (2012) · PubMed · Cited by 34

MULTI-SENSORY INTERVENTION OBSERVATIONAL RESEARCH

Thompson, C. J. (2011) · International Journal of Special Education (IJSE) · Cited by 34

Sensorimotor versus Fine Motor Activities in Eliciting Vocalizations in Autistic Children

Reilly, C., Nelson, D. L., & Bundy, A. C. (1983) · The Occupational Therapy Journal of Research · doi:10.1177/153944928300300402 · Cited by 29

AChanDietary Intervention Enhances Executive Functions and Anterior Cingulate Activity in Autism Spectrum Disorders: A Randomized Controlled Trial

Chan, A. S.-Y., Sze, S. L., Han, Y. M. Y., & Cheung, M.-C. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/262136 · Cited by 27

Effectiveness and Tolerability of Switching to Aripiprazole From Risperidone in Subjects With Autism Spectrum Disorders

Ishitobi, M., Kosaka, H., Takahashi, T., Yatuga, C., Asano, M., Tanaka, Y., Ueno, K., Okazaki, R., Omori, M., Hiratani, M., et al. (2013) · Clinical Neuropharmacology · doi:10.1097/wnf.0b013e3182a31ec0 · Cited by 26

Seven-Star Needle Stimulation Improves Language and Social Interaction of Children with Autistic Spectrum Disorders

Chan, A. S.-Y., Cheung, M., Sze, S. L., & Leung, W. W.-M. (2009) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x09007004 · Cited by 26

Music in the Assessment and Treatment of Echolalia

Bruscia, K. E. (1982) · Music Therapy · doi:10.1093/mt/2.1.25 · Cited by 25

A Systematic Review of the Literature on the Chiropractic Care of Patients with Autism Spectrum Disorder

Alcantara, J., Alcantara, J., & Alcantara, J. (2011) · EXPLORE · doi:10.1016/j.explore.2011.08.001 · Cited by 24

The Immune System and Complementary and Alternative Medicine

Cooper, E. L. (2007) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/nem093 · Cited by 23

Adverse Effects of Risperidone in Children with Autism Spectrum Disorders in a Naturalistic Clinical Setting at Siriraj Hospital, Thailand

Boon‐yasidhi, V., Jearnarongrit, P., Tulayapichitchock, P., & Tarugsa, J. (2014) · Psychiatry Journal · doi:10.1155/2014/136158 · Cited by 23

Yokukansan (TJ-54) for treatment of pervasive developmental disorder not otherwise specified and Asperger’s disorder: a 12-week prospective, open-label study

Miyaoka, T., Wake, R., Furuya, M., Liaury, K., Ieda, M., Kawakami, K., Tsuchie, K., Inagaki, T., & Horiguchi, J. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-215 · Cited by 20

Energy consumption in spasticity

Roberts, A. P., Stewart, C., Cole, G. F., Farmer, S., & Patrick, J. (2002) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162201222075 · Cited by 20

Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury

Bennett, M. H., Trytko, B., & Jonker, B. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004609.pub2 · Cited by 17

Is the prevalence of autism increasing in the United States?

Blenner, S., & Augustyn, M. C. (2014) · BMJ · doi:10.1136/bmj.g3088 · Cited by 16

Influence of flavonoid-rich fraction from Spermacoce hispida seed on PPAR-alpha gene expression, antioxidant redox status, protein metabolism and marker enzymes in high-fat-diet fed STZ diabetic rats

Kaviarasan, K., & Pugalendi, K. V. (2009) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp.2009.20.2.141 · Cited by 16

An intranasal herbal medicine improves executive functions and activates the underlying neural network in children with autism

Chan, A. S.-Y., Sze, S. L., & Han, Y. M. Y. (2014) · Research in Autism · doi:10.1016/j.rasd.2014.03.007 · Cited by 13

‘Energy consumption in spasticity’

Roberts, A. P., Stewart, C., Cole, G. F., Farmer, S., & Patrick, J. (2002) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2002.tb00808.x · Cited by 7

Tongue Acupuncture and Autism Spectrum Disorder

Wong, Y.-M. (2010) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2010.0615 · Cited by 5

Music Therapy and Hormonal Responses in Autism

İşeri, E. (2014) · Gazi Medical Journal · doi:10.12996/gmj.2014.16 · Cited by 5

786 Elemental Formula Diet in Autistic Children

Karkelis, S., Papadaki-Papandreou, O., Lykogeorgou, M., Papandreou, T., Lianou, L., & Chrousos, G. P. (2010) · Pediatric Research · doi:10.1203/00006450-201011001-00786 · Cited by 2

Personal Control and the Ecology of Community Living Settings: Beyond Living-Unit Size and Type

Stancliffe, R. J., Abery, B. H., & Smith, J. (2000) · American Journal on Mental Retardation · doi:10.1352/0895-8017(2000)105

Identification, Evaluation, and Management of Children With Autism Spectrum Disorder

Hyman, S. L., Levy, S. E., Myers, S. M., COUNCIL ON CHILDREN WITH DISABILITIES, S. O. D. A. B. P., Kuo, D. Z., Apkon, S., Davidson, L. F., Ellerbeck, K. A., Foster, J. E. A., Noritz, G. H., et al. (2020) · Pediatrics · doi:10.1542/peds.2019-3447 · Cited by 1,798

Autism Spectrum Disorder: Classification, diagnosis and therapy

Sharma, S., Gonda, X., & Tarazi, F. I. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.05.007 · Cited by 745

Evidence-based support for autistic people across the lifespan: maximising potential, minimising barriers, and optimising the person–environment fit

Lai, M.-C., Anagnostou, E., Wiznitzer, M., Allison, C., & Baron-Cohen, S. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30034-x · Cited by 250

Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials

Mazahery, H., Stonehouse, W., Delshad, M., Kruger, M. C., Conlon, C. A., Beck, K. L., & von Hurst, P. R. (2017) · Nutrients · doi:10.3390/nu9020155 · Cited by 146

Music therapy for autistic people

Geretsegger, M., Fusar‐Poli, L., Elefant, C., Mössler, K. A., Vitale, G., & Gold, C. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004381.pub4 · Cited by 163

Review Article Complementary and Alternative Therapies for Autism Spectrum Disorder

Brondino, N., Fusar‐Poli, L., Rocchetti, M., Provenzani, U., Barale, F., & Politi, P. (2016)

Complementary and Alternative Medicine for Autism

Kim, T., Lee, M. S., Choi, J., & Ernst, E. K. (2013) · Springer eBooks · doi:10.1007/978-1-4614-4788-7_135

A Review for Existing Complementary and Alternative Medical Therapies for Autism Spectrum Disorder

Yin, X. (2020) · Journal of Psychological Research · doi:10.30564/jpr.v2i4.2236 · Cited by 1

The effects of complementary and alternative medicine therapies on individuals with autism spectrum disorder: A systematic review

Rawwash, A. A., Youssef, M. A. F. M., & Negm, S. H. I. (2025) · Journal of Research in Ayurvedic Sciences · doi:10.4103/jras.jras_349_25

Global characteristics of the use of complementary and alternative medicine for autism spectrum disorder: a scoping review protocol

Willcox, G. M., Shead, D. A., & Maseko, B. C. (2026) · JBI Evidence Synthesis · doi:10.11124/jbies-25-00264