The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology
Open accessAbstract
Hydrogen sulfide (H 2 S) has emerged as a relevant signaling molecule in physiology, taking its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide (CO). After being merely regarded as a toxic poisonous molecule, it is now recognized that mammalian cells are equipped with sophisticated enzymatic systems for H 2 S production and breakdown. The signaling role of H 2 S is mainly related to its ability to modify different protein targets, particularly by promoting persulfidation of protein cysteine residues and by interacting with metal centers, mostly hemes. H 2 S has been shown to regulate a myriad of cellular processes with multiple physiological consequences. As such, dysfunctional H 2 S metabolism is increasingly implicated in different pathologies, from cardiovascular and neurodegenerative diseases to cancer. As a highly diffusible reactive species, the intra‐ and extracellular levels of H 2 S have to be kept under tight control and, accordingly, regulation of H 2 S metabolism occurs at different levels. Interestingly, even though H 2 S, NO, and CO have similar modes of action and parallel regulatory targets or precisely because of that, there is increasing evidence of a crosstalk between the three gasotransmitters. Herein are reviewed the biochemistry, metabolism, and signaling function of hydrogen sulfide, as well as its interplay with the other gasotransmitters, NO and CO.
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Cites
Nitric oxide and the immune response
Bogdan, C. (2001) · Nature Immunology · doi:10.1038/ni1001-907 · Cited by 3,447
H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase
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Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling
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Chemical foundations of hydrogen sulfide biology
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On the chemical biology of the nitrite/sulfide interaction
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PNP-Perthionitrit und PNP-Monothionitrit / PNP-Perthionitrite and PNP-M onothionitrite
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“In contrast, by characterizing pure crystalline SSNO prepared as a bis(triphenylphosphine)iminium (PNP) salt according to [179], Filipovic et al.”
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Cited by
Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace
Chinemerem Nwobodo, D., Ugwu, M. C., Oliseloke Anie, C., Al‐Ouqaili, M. T. S., Chinedu Ikem, J., Victor Chigozie, U., & Saki, M. (2022) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.24655 · Cited by 985
Metadata
- Authors
- Giuffrè, A., & Vicente, J. B.
- Venue
- Oxidative Medicine and Cellular Longevity
- Publisher
- Wiley
- Published
- 2018-01
- Volume
- 2018
- Issue
- 1
- Pages
- 6290931-6290931
- ISSN
- 1942-0994 (ISSN-L)
- 1942-0900
- OpenAlex
- W2810415057
- Cited by
- 165
- References
- 13
- FWCI
- 6.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Giuffrè, A., & Vicente, J. B. (2018). Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2018/6290931
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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